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SCANNING ELECTRON MICROSCOPY OF CANDIDA ALBICANS CELL WALL ON TOOTH SURFACE AFTER FLUCONAZOLE-TREATED AND INCUBATED WITH GUAVA (PSIDIUM GUAJAVA L) Abdillah Imron Nasution; Basri Basri
Journal of Syiah Kuala Dentistry Society Vol 2, No 2 (2017): JULY
Publisher : Dentistry Faculty

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Abstract

The Candida albicans cell wall is a target of fluconazole. The content of guava (Psidium guajava L) known have contribute factors to resistance of fluconazole. Objective: characterize the surface alterations and the general shape changes of candida cells after in vitro exposure to fluconazole and guava. Material and Methods: six tooth specimen groups: Cells exposed without fungicidal doses (Negative Control), Positive Cells exposed to maximal fungicidal doses of Fluconazole (100g/ml) (Control), Guava (G), Guava+Fluconazole susceptibility (GFS), Guava+Fluconazole Susceptible-Dose Dependent (GFSDD), Guava+Fluconazole dose Resistance (GFR). Each group mixed with 10 ml artificial saliva, 2 ml glucose 2%, and 2 ml C. albicans. Fluconazole doses based on NCCLS approved M27-A. Scaninng Electron Microscopy conducted after 15 days incubation at Faculty of Veterinary University of Syiah Kuala and Faculty of Engineering University of Indonesia. Results, SEM of Negative Control presented smooth of blastospores; small clusters of interconnected cells, spherical to elongate in shape, lying down, polar buds, and hyphae on dental surface. SEM of Positive Control and Guava generally presented: wrinkled of blastospores, rough surfaces, cells fewer than Negative Control, and lying apart. Positive Control showed spherical to elongate in shape and Guava with spherical in shape presented more wrinkled than Positive Control. SEM of GGF and Guava+Fluconazole Susceptible-Dose Dependent presented wrinkled of blastospores, rough surfaces, decreased in number, spherical to elongate in shape, lying apart, and hyphae on surface. SEM of Guava+Fluconazole dose Resistance presented wrinkled of blastospores but more smooth than others, elongate in shape; buds orientations penetrate to dental tissue. Conclusion: Guava improving the integrity of cell wall of Candida albicans and contributed to resistance of Candida albicans to fluconazole.Keywords: Candida albicans, Guava, Fluconazole, Scanning Electron Microscopy
Internalization Internalization of Tolerance Values through Akidah Akhlak Learning at MAN 1 Pringsewu and MA Darul Ulum Mz, Riza Arif; Basri Basri; Ahmad Barizi
Khatulistiwa: Jurnal Pendidikan dan Sosial Humaniora Vol. 4 No. 4 (2024): Desember: Jurnal Pendidikan dan Sosial Humaniora
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/khatulistiwa.v4i4.7402

Abstract

The lack of integration of tolerance and multiculturalism education has resulted in the continued prevalence of intolerant and radical attitudes among society and the younger generation.This study aims to describe the implementation and internalization process of tolerance values ​​through Akidah Akhlak learning at MAN 1 Pringsewu and MA Darul Ulum and to identify its impact on students' attitudes. The study used a qualitative approach with data collection techniques through observation, interviews, and documentation. The results showed that MAN 1 Pringsewu emphasized cognitive and affective approaches in tolerance learning, such as through the delivery of material "Teenager Social Akhlak" and the screening of educational videos. Meanwhile, at MA Darul Ulum, the internalization process was carried out using a value classification approach, where students actively identified tolerant and intolerant attitudes through group discussions and the habituation of polite attitudes. The impact of the internalization of tolerance values ​​in both madrasas was seen in the increasing awareness of students to respect differences, maintain polite attitudes, and avoid deviant behavior both in and outside the school environment. This study emphasizes the importance of integrating tolerance values ​​in learning as a foundation for forming students' character amidst social diversity. Abstrak. Kurangnya integrasi pendidikan toleransi dan multikulturalisme menyebabkan masih maraknya sikap intoleran dan radikalisme di kalangan masyarakat dan generasi muda. Penelitian ini bertujuan untuk mendeskripsikan implementasi dan proses internalisasi nilai-nilai toleransi melalui pembelajaran Akidah Akhlak di MAN 1 Pringsewu dan MA Darul Ulum serta mengidentifikasi dampaknya terhadap sikap siswa. Penelitian menggunakan pendekatan kualitatif dengan teknik pengumpulan data melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa MAN 1 Pringsewu menekankan pendekatan kognitif dan afektif dalam pembelajaran toleransi, seperti melalui penyampaian materi “Akhlak Pergaulan Remaja” dan pemutaran video edukatif. Sementara itu, di MA Darul Ulum, proses internalisasi dilakukan dengan pendekatan klasifikasi nilai, di mana siswa aktif mengidentifikasi sikap toleran dan intoleran melalui diskusi kelompok dan pembiasaan sikap santun. Dampak dari internalisasi nilai toleransi di kedua madrasah tampak pada meningkatnya kesadaran siswa untuk menghargai perbedaan, menjaga sikap santun, serta menghindari perilaku menyimpang baik di lingkungan sekolah maupun di luar sekolah. Penelitian ini menegaskan pentingnya integrasi nilai-nilai toleransi dalam pembelajaran sebagai fondasi membentuk karakter peserta didik di tengah keberagaman sosial. Kata Kunci: Internalisasi, Nilai Toleransi, Akidah Akhlak, MAN 1 Pringsewu, MA Darul Ulum
The Influence Of The Quality Of Fiskus Services, Tax Sanctions, And The Taxpayer's Environment On Individual Taxpayer Compliance With Account Representative Professionalism As A Moderating Variable In The Pratama Batam North Tax Services Office Basri Basri; Yuliansyah Yuliansyah; Bambang Satriawan
International Journal of Economics and Management Research Vol. 2 No. 3 (2023): December : International Journal of Economics and Management Research
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijemr.v2i3.127

Abstract

Individual taxpayers who carry out their obligations experience fluctuations from year to year, but there are several years that actually experience a significant decline. The level of taxpayer compliance continues to experience waves of ups and downs, so it can be said that there is instability in taxpayer compliance which shows a less good trend. The percentage shown is quite high, but actually still has not reached the maximum target. The purpose of this study was to determine and analyze the effect of service quality, tax sanctions, and taxpayer environment on taxpayer compliance directly or moderated by Account Representative Professionalism the nature of testing the relationship between variables. The research population was 67,957 individual taxpayers registered at KPP Pratama Batam Utara with sampling techniques using the Slovin formula with a leeway of 100%, a sample of 100 people was obtained. The data analysis technique uses path analysis techniques with the help of PLS Ver statistical tools 3. The results of data analysis were obtained. The quality of Fiskus services has a positive and insignificant effect on individual taxpayer compliance at KPP Pratama Batam Utara. Tax sanctions have a positive and significant effect on individual taxpayer compliance at KPP Pratama Batam Utara. The taxpayer environment has a positive and significant effect on individual taxpayer compliance at KPP Pratama Batam Utara. Professional account representatives moderate the effect of the quality of tax authorities' services positively and insignificantly on individual taxpayer compliance at KPP Pratama Batam Utara with moderation qualification is Homologizer moderator. Professional account representatives moderate the effect of tax sanctions negatively and significantly on individual taxpayer compliance at KPP Pratama Batam Utara with moderation qualification is Quasi moderator. Professional account representative moderates the influence of taxpayer environment negatively and significantly on individual taxpayer compliance at KPP Pratama Batam Utara with moderation qualification as Quasi moderator.