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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medula Jurnal Kesehatan Holistic Jurnal Dunia Kesmas JKM (Jurnal Kebidanan Malahayati) Jurnal Ilmu Kedokteran dan Kesehatan Community Development Journal Reswara: Jurnal Pengabdian Kepada Masyarakat JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Kedokteran Raflesia ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Pengabdian Pada Masyarakat
Novita Carolia
Bagian Farmakologi, Fakultas Kedokteran, Universitas Lampung
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Journal : Jurnal Kesehatan Holistic

 1 
Efek Perasan Rimpang Kunyit (Curcuma longa L.) Terhadap Gambaran Epitel Lambung Mencit yang Diinduksi Indometasin Shabrina, Annisa Firra; Carolia, Novita; Tjiptaningrum, Agustyas
Jurnal Kesehatan Holistic Vol. 8 No. 1 (2024): Jurnal Kesehatan Holistic Volume 8/ Nomor 1/ Juli 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan RS Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33377/jkh.v8i1.188

Abstract

Background: Gastric ulcers are stomach lesions characterized by depleted mucosa with the defect extending into the submucosa or muscularis propria. Gastric ulcers could be caused by the use of Indomethacin as an analgesic drug. Turmeric rhizome is a herbal plant that contains curcumin which has been suspected to play a role in gastric ulcer prevention. Objective: The aim of this study was to perceive the effect of turmeric rhizome juice with concentrations of 100%, 75%, and 50% on indomethacin-induced gastric epithelium image in mice. Methods: This experimental study with a Post Test Only Control design was conducted by using 25 samples of male ddY mice for 3 days intervention. Samples were divided into 5 groups, two control groups, and three intervention groups. The organ samples had been observed by assessing the gastric epithelium injury of mice on the antrum under a microscope with an objective lens 100x for eight fields of view. Results: The Kruskal-Wallis test had been used for analysis and showed a p-value of 0,025 which means it had a significant difference. Turmeric juice with concentrations of 100%, 75%, and 50% showed different effects on mice gastric epithelium image induced by Indomethacin (18 mg/kg). Conclusion: There were different effects of turmeric juice on gastric epithelium image induced by Indomethacin in mice.
Efek Perasan Rimpang Kunyit (Curcuma longa L.) Terhadap Gambaran Epitel Lambung Mencit yang Diinduksi Indometasin Shabrina, Annisa Firra; Carolia, Novita; Tjiptaningrum, Agustyas
Jurnal Kesehatan Holistic Vol. 8 No. 1 (2024): Jurnal Kesehatan Holistic Volume 8/ Nomor 1/ Juli 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan RS Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33377/jkh.v8i1.188

Abstract

Background: Gastric ulcers are stomach lesions characterized by depleted mucosa with the defect extending into the submucosa or muscularis propria. Gastric ulcers could be caused by the use of Indomethacin as an analgesic drug. Turmeric rhizome is a herbal plant that contains curcumin which has been suspected to play a role in gastric ulcer prevention. Objective: The aim of this study was to perceive the effect of turmeric rhizome juice with concentrations of 100%, 75%, and 50% on indomethacin-induced gastric epithelium image in mice. Methods: This experimental study with a Post Test Only Control design was conducted by using 25 samples of male ddY mice for 3 days intervention. Samples were divided into 5 groups, two control groups, and three intervention groups. The organ samples had been observed by assessing the gastric epithelium injury of mice on the antrum under a microscope with an objective lens 100x for eight fields of view. Results: The Kruskal-Wallis test had been used for analysis and showed a p-value of 0,025 which means it had a significant difference. Turmeric juice with concentrations of 100%, 75%, and 50% showed different effects on mice gastric epithelium image induced by Indomethacin (18 mg/kg). Conclusion: There were different effects of turmeric juice on gastric epithelium image induced by Indomethacin in mice.
Co-Authors Agustyas Tjiptaningrum Akbar, Muhammad Zakky Putra Amourisva, Azqiya Putri Anggraeni, Liza Ari Wahyuni Asep Sukohar Daulay, Suryani Agustina Dian Isti Angraini Dwi Indria Anggraini Dwiputri, Maliya Finda Efriyan Imantika Erna Kristin Fathaniah, Widya Fathia, Nauriel Fitri, Dilla Syahra Noor Fitria Saftarina Giska Tri Putri Hendra Tarigan Sibero Husnandari, Aqila Ihsanti Dwi Rahayu Indri Windarti Isti Anggraini, Dian Izdihar, Adinda Fairuz Jausal, Annisa Nuraisa Karyus, Aila Liana Sidharti, Liana Marcellia, Selvi Mayasari, Diana Mustofa Mustofa Naufal, Muhammad Ariq Ningrum, Adenias Lutfia Novadela, Nora Isa Tri Nurchairina, Nurchairina Putri, Meilani Putri, Meilani Dwi Putri, Syalika Dianisa Ramadhan, Muhammad Alif Rasmi Zakiah Oktarlina Rasyid, Risneni Risti Graharti Rosa, Emantis Shabrina, Annisa Firra Sofyan Musyabiq Wijaya Soraya Rahmanisa Sri Waluyo Susianti Sutarto Sutarto Syazili Mustofa TA Larasati Utama, WInda Trijayanti Wijaya, Sofyan Winda Trijayanthi Utama, Winda Trijayanthi Wisnugroho, Cahyo Wiwi Febriani Zetira, Zihan Zulfa, Fathimah