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FORMULASI DAN UJI FISIK SALEP KOMBINASI EKSTRAK PUTRI MALU (Mimosa Pudica) DAN DAUN JARAK PAGAR (Jatropha Curcas) Enjelina, Sinta Mei; Pambudi, Risma Sakti; Ramadhani, Mutia; Subiyanto, Abyasa Fajari; Ilmi, Ibnul; Rahmadin, Mega Tri
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1114

Abstract

Indonesia is a tropical country that has the potential to experience skin diseases. The development of drugs from natural ingredients can be used to treat skin diseases. One of the appropriate pharmaceutical preparations for treating skin infections is ointment. Putri Malu (Mimosa Pudica) and Jatropha Leaves (Jatropha Cuscas) are plants that contain flavonoids, alkaloids, saponins, tannins and phenols which have the potential to inhibit bacterial growth. The aim of this research is to formulate an ointment preparation from the extract of putrimalu (mimosa pudica) and jatropha curcas leaves (jatropha curcas) which meets the requirements of an ointment preparation by means of a physical test of the ointment. This type of research was experimental, which was carried out by making 3 ointment formulations combining Putri Malu and Jatropha leaves using the ointment base Vasellin Album and Adeps Lanae. Physically tested ointment preparations include organoleptic tests, homogeneity tests, pH tests, viscosity tests, spreadability tests, and adhesiveness tests. Based on testing of a combination of ointment preparations from the extract of putrimalu (mimosa pudica) and jatropha leaves (jatrooha cuscas) with a base of vasellin album and adeps lanae, the organoleptic results were blackish brown, distinctive odor, semi-solid consistency, homogeneous ointment with a Ph value of 5 and viscosity test. adhesion and spreading power in accordance with ointment preparation standards. The best formulation of the ointment combination of the extract of the mollusk (mimosa pudica) and jatropha curcas (jatropha cusrcas) leaves is formulation 2 with a ratio of (2:2).
Efektivitas Biaya Antibiotik Pada Pasien Demam Tifoid Di Klinik X Sragen Akhyani, Nur; Pambudi, Risma Sakti; Khusna, Khotimatul
Majalah Farmaseutik Vol 20, No 4 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v20i4.85941

Abstract

Demam tifoid merupakan penyakit infeksi sistemik bersifat akut yang dapat disebabkan oleh bakteri Salmonella typhi dan dapat diterapi dengan menggunakan obat antibiotik. Penggunaan antibiotik yang tidak tepat dapat menimbulkan potensi peningkatan kejadian bakteri yang resisten terhadap antibiotik dan dapat meningkatkan biaya perawatan. Tujuan penelitian ini adalah untuk mengetahui efektivitas biaya penggunaan antibiotik pada pengobatan pasien demam tifoid di Klinik Pratama Gumilang Larasati Sragen tahun 2022. Penelitian ini bersifat deskriptif yaitu mengambil data secara retrospektif melalui data rekam medis yang berisi data seluruh pasien demam tifoid tahun 2022 yaitu sebanyak 96 rekam medis. Metode analisis biaya yang digunakan adalah Cost Effectiveness Analysis (CEA) dan metode Average Cost Effectiveness Ratio (ACER) untuk menganalisis terapi pengobatan demam tifoid yang paling cost effective. Hasil menunjukkan bahwa penggunaan terapi pasien demam tifoid di Klinik Pratama Gumilang Larasati Sragen tahun 2022 menggunakan terapi antibiotik injeksi cefotaxime dengan nilai ACER Rp. 18.513, injeksi ceftriaxone dengan nilai ACER Rp. 21.306 dan infus levofloxacin dengan nilai ACER Rp. 32.446. Kesimpulan dari penelitian ini adalah obat yang dinilai paling cost effective adalah penggunaan antibiotik injeksi cefotaxime dengan nilai ACER Rp. 18.513.
KAJIAN PENINGKATAN PENGETAHUAN FITOFARMAKA UNTUK SWAMEDIKASI PADA TIM PENGGERAK PKK DI SURAKARTA: A STUDY ON IMPROVING PHYTOPHARMACA KNOWLEDGE FOR SELF-MEDICATION IN THE PKK MOBILIZATION TEAM IN SURAKARTA Pambudi, Risma Sakti; Khusna, Khotimatul; Safitri, Desti Anggi; Windiasari, Farah Puteri
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1755

Abstract

Public knowledge related to the use of traditional medicine is still low and does not know other traditional medicine classes such as OHT (Standardized Herbal Medicine) and phytopharmaca groups. The purpose of this study was to determine the level of knowledge of the use of phytopharmaca for self-medication in the PKK team of Surakarta city. The method in this study used quantitative research with a quasi experimental design with one group pre and post test design. The pre-test was used at the time of the delivery of the material with the aim of knowing the extent to which the material was understood by the respondents. While the post-test is carried out at the end of the material treatment process with the aim of knowing the extent of understanding of the material provided.  Analyze respondents' knowledge by looking at the formula to measure the percentage of answers obtained from the questionnaire. The results showed the level of knowledge of respondents during the pre-test, namely having good knowledge (39.22%), sufficient knowledge (48.04%) and less (12.75%). After being given treatment, respondents filled out a questionnaire and obtained a value for the post-test knowledge level, namely good (63.73%), sufficient (30.39%), and less (12.75%). The results showed that there was a difference in the pre and post test scores of respondents after being treated with a sig value (2-tailed) of 0.000, which is <0.05. The conclusion of this study is that there is an average difference between pre and post and there is an effect with a sig value of 0.000, which is <0.05. Keywords:  Medicine, Phytopharmaca, Knowledge, Self-medication, Surakarta
Edukasi Pada Ibu PKK Tapak Siring Tentang Sistem Informasi Pengelolaan Obat Mandiri (SIPOM) Pambudi, Risma Sakti; Khusna, Khotimatul; Fitriyadi, Farid
Reswara: Jurnal Pengabdian Kepada Masyarakat Vol 6, No 1 (2025)
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/rjpkm.v6i1.4987

Abstract

Pengobatan secara mandiri tanpa pengetahuan yang baik dapat memiliki risiko terjadi kesalahan dalam penggunaan obat.  Terdapat Masyarakat yang kebingungan dalam mengelola obat yang tidak terpakai atau obat sisa di rumah. Semakin meningkatnya kemajuan teknologi informasi yang digunakan untuk berbagai aspek. Tujuan kegiatan Pengabdian Kepada Masyarakat ini adalah untuk memberikan pemahaman tentang pengelolaan obat mandiri melalui edukasi DAGUSIBU dengan menggunakan sistem informasi. Metode yang dilakukan yaitu dengan memberikan edukasi melalui media website dan diskusi. Evaluasi kegiatan dilakukan dengan melihat pemahaman peserta tentang menggunakan website SIPOM dan informasi penggunaan obat baik sebelum dan sesudah dilakukannya edukasi. Evaluasi kegiatan pengabdian dilihat dari jawaban peserta saat menjawab pertanyaan diberikan oleh pemateri. Hasil menunjukkan jumlah peserta kegiatan ini adalah 24 peserta. Hasil evaluasi menunjukkan terdapat peningkatan pengetahuan sebelum diberikan edukasi terdapat 10 orang (41,67%) yang memahami tentang pengelolaan obat secara mandiri dan setelah dilakukan edukasi terjadi peningkatan peserta yang memahami yaitu menjadi 24 peserta (100%) yang diuji dengan SPSS dengan nilai sig2-tailed p<0.05. Kesimpulan dari kegiatan ini adalah Kegiatan pengabdian masyarakat terkait edukasi SIPOM dapat mempermudah keterjangkauan Masyarakat dalam mencari informasi pengelolaan obat secara mandiri. 
Identifikasi Drug Related Problems Pasien Hipertensi dengan Gagal Ginjal Kronik di Instalasi Rawat Inap RSUD Raja Ahmad Tabib Kepulauan Riau Ruth Eva Betriana; Risma Sakti Pambudi; Khotimatul Khusna
An-Najat Vol. 3 No. 2 (2025): Mei : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i2.2525

Abstract

Hypertension is one of the risk factors for cardiovascular disease and kidney disease with prevalence increasing every year. Medications for a long period of time and using a combination of drugs (polypharmacy) are at risk of Drug Related Problems (DRPs). DRPs are events or conditions associated with drug therapy that actually or potentially interfere with desired clinical health outcomes. The purpose of this study was to determine the identification of Drug Related Problems that occurred in hypertensive patients with chronic renal failure in the inpatient installation of Raja Ahmad Tabib Hospital Riau Islands. The research method used is non-experimental, descriptive and retrospective research. The number of samples was 60 who met the inclusion criteria. The sample used is data from medical records of hypertensive patients with chronic renal failure for the period January to December 2022. Based on the results of the study, it was found that 52 patients (86.67%) experienced DRPs, with the number of potential DRPs indications without therapy as many as 5 patients (8.33%), inappropriate drug selection as many as 2 patients (3.33%) and drug interactions. as many as 45 patients (75%).
Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis pada Pasien TB di Puskesmas Kota II, Kabupaten Mappi, Provinsi Papua Selatan Grace Agnes Theresa Konowok; Khotimatul Khusna; Risma Sakti Pambudi
An-Najat Vol. 3 No. 2 (2025): Mei : An-Najat : Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v3i2.2528

Abstract

Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis bacteria. Transmission of TB can be transmitted through droplets from people infected with tuberculosis bacilli. Tuberculosis is very much determined by the success of treatment in order to prevent all complications caused by tuberculosis. This study aims to determine the level of compliance with the use of anti-tuberculosis drugs in TB patients at the Kota II health center, Mappi Regency, South Papua Province. This study is a study using a descriptive observational method. The research instrument used in this study was the MMAS-8 (Modified MoriskyAdherence 8-Scale) questionnaire with 8 questions that have been tested for validation and reliability. Based on the results of the study, it was found that 25% of patients had a good level of compliance, 21.25% of patients had a sufficient level of compliance, and 53.75% had a low level of compliance. The researcher's conclusion shows that most of the respondents at the Kota II Community Health Center, Mappi Regency, South Papua Province had a low level of compliance with a presentation of 53.75%.
Pengaruh Edukasi terhadap Tingkat Pengetahuan Penggunaan Antibiotik pada Pasien Rawat Jalan di Puskesmas Perawatan Buli: The Effect of Education on The Level of Knowledge of Antibiotic Use in Outpatients at Buli Health Care Center Primania Maria Puren; Khusna, Khotimatul; Risma Sakti Pambudi
Indonesian Journal of Pharmacy and Natural Product Vol. 8 No. 01 (2025): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v8i01.3003

Abstract

Antibiotics are drugs which has a function to kill bacteria. Antibiotics are ethical drugs that are often used in pharmacological therapy. Low levels of knowledge regarding the use of antibiotics can result in irrational use, thereby risking antibiotic side effects. Providing education is one way that can be used to increase knowledge about antibiotics in patients. The aim of this study was to determine the effect of providing education on the level of knowledge of outpatients about antibiotics at the Buli Health Care Center. This research method is quasi experimental using a one group pre and post-test design and data collection from a perspective using purposive sampling technique for 96 respondents. The research results showed that 57.3% (55 respondents) obtained antibiotics without a doctor's prescription and 42.7% (41 respondents) obtained a doctor's prescription. During the pre-test, 22.9% (22 respondents) were in the poor category, 41.7% (40 respondents) in the sufficient category, 35.4% (34 respondents) in the good category. In the post-test 20.8% (20 respondents) were in the fair category, 32.3% (31 respondents) in the good category, 46.9% (45 respondents) in the very good category. The results obtained were tested using the Wilcoxon signed rank which shows the difference in scores between before and after being given education with a significant value of 0.00 (p value <0.05). The conclusion of this study is that there is an influence of education on the level of knowledge of outpatients at the Buli Care Community Health Center.   ABSTRAK Antibiotik adalah obat yang berfungsi membunuh bakteri. Antibiotik termasuk dalam golongan obat keras yang sering digunakan pada tatalaksana terapi farmakologi. Rendahnya tingkat pengetahuan mengenai penggunaan antibiotik dapat mengakibatkan penggunaan yang tidak rasional, sehingga berisiko menimbulkan efek samping antibiotik. Pemberian edukasi adalah salah satu cara yang bisa digunakan untuk meningkatkan pengetahuan tentang antibiotik pada pasien. Tujuan penelitian ini untuk mengetahui pengaruh pemberian edukasi terhadap tingkat pengetahuan pasien rawat jalan tentang antibiotik di Puskesmas Perawatan Buli. Metode penelitian ini adalah quasi experimental menggunakan desain one group pre and post-test dan pengambilan data secara perspektif dengan tekhnik purposive sampling kepada 96 responden. Hasil penelitian didapatkan antibiotik diperoleh tanpa resep dokter 57,3% (55 responden) dan dengan resep dokter 42,7% (41 responden). Saat pre-test 22,9% (22 responden) kategori kurang, 41,7% (40 responden) kategori cukup, 35,4% (34 responden) kategori baik. Pada post-test 20,8% (20 responden) kategori cukup, 32,3% (31 responden) kategori baik, 46,9% (45 responden) kategori sangat baik. Hasil yang diperoleh diuji menggunakan Wilcoxon signed rank yang menunjukkan perbedaan skor antara sebelum dan sesudah diberikan edukasi dengan nilai signifikan 0,00 (pvalue<0,05). Kesimpulan pada penelitian ini adalah terdapat pengaruh edukasi terhadap tingkat pengetahuan pasien rawat jalan di Puskesmas Perawatan Buli.
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN MINUM OBAT PADA PASIEN HIPERTENSI DI PUSKESMAS MANAHAN SURAKARTA Widodo, Arvia Wahyu; Pambudi, Risma Sakti; Ahwan, Ahwan
Jurnal Farmasi & Sains Indonesia Vol 6 No 2 (2023)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol6no2p1-7

Abstract

Hypertension is an increase in systolic blood pressure more than equal to 140 mmHg and diastolic more than equal to 90 mmHg. Good knowledge must be possessed by people with hypertension in order to better understand the importance of routine blood pressure control and to know the dangers caused if they do not take medication regularly. Compliance with taking antihypertensive medication is very important to increase the effectiveness of treatment and prevent complications. This study aims to determine the relationship between the level of knowledge and medication adherence in hypertensive patients at the Manahan Surakarta Health Center. The method used is an analytic observational method with a cross sectional approach. The instruments used in this study were the HK-LS (Hypertension Knowledge-Level Scale) questionnaire and the MMAS-8 (Morisky Medication Adherence) questionnaire to obtain primary data. Data collection was conducted in March 2023 with a sample size of 100 hypertensive patients. Knowledge of hypertension is low knowledge of 8%, moderate knowledge of 23% and high knowledge of 69%. The results of the presentation of medication adherence are low adherence of 16%, moderate adherence of 29%, high adherence of 55%. Based on bivariate analysis using Spearman's rank analysis a correlation coefficient of 0.571 was obtained with a p value of 0.000 <0.05 which means that Ho was rejected and Ha was accepted, that is, there was a significant relationship between knowledge about hypertension and adherence to taking medication in hypertensive patients at the Manahan Surakarta Health Center.
TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK X KOTA SURAKARTA Pambudi, Risma Sakti; Ulfah, Amalia; Khusna, Khotimatul
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 2 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i2.8497

Abstract

Kepuasan pasien merupakan salah satu indikator penting dalam menilai kualitas pelayanan di apotek. Pelayanan kesehatan dikatakan bermutu apabila mampu memberikan kepuasan bagi pasien yang dilayani. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien terhadap pelayanan kefarmasian di Apotek x kota Surakarta. Penelitian ini menggunakan metode analisis deskriptif dengan menggunakan kuesioner yang diberikan kepada 100 responden. Pengambilan sampel menggunakan teknik accidental sampling. Kuesioner terdiri dari 15 pertanyaan yang mewakili 5 dimensi. Hasil kuesioner diukur menggunakan skala Likert. Hasil persentase berdasarkan dimensi bukti fisik (tangible) mendapat nilai skala 86,6% (sangat puas), dimensi kehandalan (reliability) mendapat nilai skala 82,7% (sangat puas), dimensi ketanggapan (responsiveness) mendapat nilai skala 89,3% (sangat puas), dimensi jaminan (assurance) mendapat nilai skala 87,5% (sangat puas), dimensi empati (empathy) mendapat nilai skala 90,8% (sangat puas). Berdasarkan kelima indikator kepuasan dapat disimpulkan bahwa tingkat kepuasan pasien terhadap pelayanan kefarmasian di Apotek x kota Surakarta yaitu sangat puas dengan rata-rata persentase sebesar 87,38%.
Profil Penggunaan Obat Tradisional pada Civitas Akademika Universitas Sahid Surakarta Rizal, Rafli Adnan; Ariastuti, Reni; Pambudi, Risma Sakti
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 2 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i2.8601

Abstract

Penggunaan obat tradisional di Indonesia masih menjadi pilihan masyarakat mengobati penyakit ringan. Tujuan dari penelitian ini adalah untuk mengetahui profil penggunaan obat tradisional pada civitas akademika Universitas Sahid Surakarta. Penelitian ini merupakan penelitian deskriptif kualitatif dengan instrumen penelitian berupa kuesioner dalam bentuk google form. Sampel dalam penelitian ini diambil menggunakan teknik purposive sampling, dengan total responden sebanyak 159 orang dari civitas akademika Universitas Sahid Surakarta. Teknik analisis dilakukan secara deskriptif dengan melihat persentase profil penggunaan obat tradisional. Kuesioner dilakukan uji validitas dengan metode Content Validity Index mendapatkan nilai 1 pada angket keseluruhan dan butir angket yang berarti valid. Hasil uji reliabilitas dengan nilai Cronbach’s Aalpha 0,89 untuk angket keseluruhan dan 0,91 untuk butir angket yang berarti reliabel. Hasil penelitian menunjukkan jamu merupakan jenis obat tradisional yang paling sering digunakan (50,94%), persentase terbesar menunjukkan bahwa sediaan yang paling sering digunakan adalah dalam bentuk cair (54,71%), sebagian besar responden memanfaatkan obat tradisional untuk mengatasi penyakit ringan (62,89%), dan kebanyakan responden memperoleh obat tradisional dari apotek (37,10%), sementara durasi penggunaannya paling banyak selama 2-3 (45,28%). Alasan menggunakan obat tradisional karena terbuat dari bahan alami (49,68%). Produk obat tradisional yang paling banyak digunakan adalah tolak angin (28,04%). Berdasarkan hasil penelitian dapat diketahui bahwa sebagian besar civitas akademika Universitas Sahid Surakarta menggunakan obat tradisional dalam bentuk jamu dengan alasan karena bebahan dasar alami dan untuk mengobati penyakit ringan.  
Co-Authors Ahmad Ghofar Wicaksono Ahwan Ahwan Ahwan Ahwan, Ahwan Akhyani, Nur Alvina Nia Diani Alvina Nia Diani Anniez Rachmawati Musslifah Ariastuti, Reni Arvia Wahyu Widodo Arvita Sari Ashinta, Faridani Anggun Astri Charolina Astuti, Winanti Puji Atika Azizah Widodo Bella Novela Dwi Utari Cahyani, Tiwi Nur Dewi, Oktaria Pratama Dwi Jayanti Indah Isnasari Dwi Jayanti Isnasari Endah Astuti Astuti Enjelina, Sinta Mei Evelyne Henny Lukitasari Fadilah Qonitah Fadilah Qonitah Farah Puteri Windiasari Firra Lurenza Pratiwi Fitriyadi, Farid Grace Agnes Theresa Konowok Grace Hestrivina Puren Hafidz, Rosyadah Hanafi, Affan Helviana Rista Rini Helviana Rista Rini Heni Rusita Ilmi, Ibnul Irfan Al Fahmi Ishariyanto, Riski Jannah, Danik Miftakhul Khotimatul Khusna Khotimatul Khusna Khusna, Khotimatul Kristianingsih, Kiki Kurniasari, Anisa Laili, Siti Annisa Alfia Lana, Bima Perkasa Putra Listiana, Endah Litta ‘Ifina Machfiroh Setianing Hati Mahmudah, Endar Asih Megananda, Jenny Meiga Susana Nabilah Rarayanthi. A Novitasari, Nur Cahyani Nur Cahyani Nur Cahyani Novitasari Novitasari Nurfadillah Nurfadillah Nursi, Ivan Nurdin Oktaria Pratama Dewi Patandung, Rosliana Primania Maria Puren Putri, Alinda Putri, Tania Ardea Rahmadin, Mega Tri Ramadhani, Mutia Reni Ariastuti Reni Ariastuti Rini, Helviana Rista Riska Dwi Astuti Rita Septiana Rita Septiana Rita Septiana Astuti Rizal, Rafli Adnan Ruth Eva Betriana Safitri, Desti Anggi Septiana, Rita Septiningrum, Chintya Hayu Solong, Sriwidyawati A. Subiyanto, Abyasa Fajari Suci, Dwi Buana Syifa Febiana Temok , Maria Gabriela M Tika Dwiyanti Tri Na'imah Ulfah, Amalia Utami, Winanti Puji Widagdo, Arisena Widodo, Arvia Wahyu Windiasari, Farah Puteri Yuliana, Sindi Wahyu Zuliana Styarini Zuriyah, Putri