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All Journal Jurnal Teknologi Dan Industri Pangan Majalah Kedokteran Bandung Jurnal Matematika & Sains Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) INDONESIAN JOURNAL OF PHARMACY Acta Pharmaceutica Indonesia JSKK (Jurnal Sains Keolahragaan dan Kesehatan) JFIOnline JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Buana Farma Jurnal Natural Kartika : Jurnal Ilmiah Farmasi
Elin Yulinah
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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EFEKTIVITAS-BIAYA PENGGUNAAN BEVACIZUMAB DAN RANIBIZUMAB SEBAGAI ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR PADA PASIEN DENGAN GANGGUAN MATA: TINJAUAN SISTEMATIS Cahyono, Nur Sidik; Sukandar, Elin Yulinah
Kartika : Jurnal Ilmiah Farmasi Vol 9 No 1 (2024)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v9i1.658

Abstract

Anti-vascular endothelial growth factor (VEGF) given by intravitreal injection can be used to treat patients with eye disorders. The anti-VEGF drugs used include bevacizumab, ranibizumab, aflibercept, and brolucizumab. These drugs are high-cost drugs, so the cost-effectiveness of each drug must be considered in order to save on treatment costs. This systematic review aims to provide a comprehensive picture of the cost-effectiveness of bevacizumab and ranibizumab. The databases used to identify relevant studies are PubMed, Science Direct and Google Scholar. This research is limited to randomized control trials (RCT), clinical trials, and research articles, studies that explain the cost-effectiveness of intravitreal injections of bevacizumab and ranibizumab and other drugs as anti-VEGF for patients with eye disorders, as well as articles in English. Electronic data-based searches resulted in 2414 articles; 27 articles were selected that had full text access and discussed the cost-effectiveness of ranibizumab or bevacizumab, but only 12 articles suitable for inclusion were considered. Bevacizumab is more cost-effective than ranibizumab.
REVIEW: INSTRUMEN KUESIONER PADA PASIEN DIABETES MELITUS Putra , Erwin Ekadharma; Hermanto, Faizal; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1113

Abstract

Diabetes mellitus (DM) is a chronic disease with increasing prevalence worldwide, posing major challenges in patient management and monitoring. Questionnaire instruments are an important tool in DM patient evaluation because they allow systematic and measurable data collection regarding various aspects of the disease, including quality of life, self-management, and perceptions of care. This review article provides a comprehensive overview of various questionnaire instruments used for DM patient evaluation, interpretation of questionnaire results, and grouping based on categories. The review results indicate that the selection of an appropriate instrument must take into account the specific context of the patient population and the evaluation goals. Additionally, we group the evaluation instruments into several categories, including the patient's level of knowledge, compliance with treatment, severity of symptoms, fear of needles, mental condition, and improvement in the patient's quality of life. The conclusion of this article emphasizes the importance of questionnaires in DM management, as well as the need for further research to develop more comprehensive and responsive instruments. Questionnaire instruments, when selected and used appropriately, can improve clinical decision-making and the quality of care provided to DM patients.
KAJIAN INTERAKSI OBAT PASIEN DIABETES DI BEBERAPA RUMAH SAKIT DI INDONESIA Aeni, Siti Nur; Sukandar, Elin Yulinah; Hermanto, Faizal
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1123

Abstract

Lebih dari 451 juta orang di seluruh dunia pada tahun 2017 diperkirakan menderita diabetes, suatu kelainan metabolik yang umum, dan diperkirakan akan meningkat menjadi 693 juta orang pada tahun 2045, atau 49,7% dari populasi orang dewasa (IDF Diabetes Atlas). Diabetes merupakan penyakit kronis yang seringkali memerlukan penggunaan kombinasi obat-obatan, sehingga meningkatkan risiko terjadinya interaksi obat. Tujuan dari penelitian ini adalah untuk menganalisis kemungkinan terjadinya interaksi obat potensial pada pasien diabetes melitus yang pernah berkunjung ke beberapa rumah sakit di Indonesia antara tahun 2014 dan 2024. Penelusuran pustaka dilakukan pada basis data Google Scholar, Pubmed dan jurnal-jurnal lainnya. Kriteria inklusi untuk publikasi artikel yang dipublikasikan selama dekade terakhir, artikel yang dipilih harus mengamati kasus-kasus interaksi obat pada pasien diabetes di rumah sakit. Penelusuran pustaka menghasilkan 10 jurnal yang relevan dan memenuhi kriteria. Hasil penelitian menyajikan potensi interaksi obat diabetes dengan berbagai obat lain berdasarkan mekanisme kerja, efek yang ditimbulkan, klasifikasi dan tingkat keparahan serta solusi yang ditampilkan. Obat diabetes yang paling banyak digunakan adalah Glimepirid dari golongan sulfonil urea. Studi interaksi obat sebagian besar bekerja secara farmakodinamik dengan tingkat keparahan sedang. Pentingnya pemantauan dan pengelolaan interaksi obat untuk meningkatkan efektivitas pengobatan dan keamanan pasien diabetes
PENGARUH KONSELING APOTEKER TERHADAP KEPATUHAN TERAPI PASIEN DIABETES MELITUS DI BEBERAPA PUSKESMAS DAN RUMAH SAKIT Putri, Mareta Ananda; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 3 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i3.1130

Abstract

Diabetes mellitus is a global health issue that requires a comprehensive management approach. Pharmacist interventions have proven effective in enhancing patient adherence to medication and improving clinical outcomes. This study aims to systematically review pharmacist interventions for diabetes mellitus patients and their impact on medication adherence and glycemic control. The research method used was a narrative literature review, analyzing 188 articles from PubMed and 200 articles from Google Scholar, with 20 studies meeting the inclusion criteria, including 12 studies conducted in community health centers (puskesmas) and 8 studies in hospitals. The findings indicate that pharmacist counseling interventions significantly improve medication adherence and lower HbA1c levels. In community health centers, adherence increased from 9.2% to 61%, and HbA1c decreased from 8.5% to 7.2%. In hospitals, the average HbA1c reduction was between 1.5% and 2%. The multifaceted counseling approach was more effective compared to telephone counseling, which showed an HbA1c reduction of 0.3%. These findings highlight the critical role of pharmacists in managing type 2 diabetes mellitus.
EVALUASI RASIONALITAS PENGGUNAAN OBAT GASTRITIS DI BEBERAPA RUMAH SAKIT : NARRATIVE LITERATURE RIVIEW Hernandi, Baso; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1191

Abstract

Gastritis is inflammation of the gastric mucosa caused by various factors, including lifestyle, food, irritation and infection. Inflammation of the stomach lining causes stomach ulcers. Based on the World Health Organization (WHO), 40.8% of Indonesia's population suffers from ulcers, and this disease is common in several large areas such as Jakarta, which is 274,396 cases out of 238,452,952 people. The World Health Organization (WHO) has turned its attention to the irrational use of drugs because more than 50% of drugs are prescribed, shipped, and sold globally without patient compliance or proper use. The purpose of this study was to review the rationality of the use of gastritis drugs in several hospitals. This study is a review of accredited journals and articles from the publication years 2019-2024. The data collection method involved analyzing fifteen journals using the relevant keywords "Rationality" and "Gastritis". Data sources were taken from the Google Scholar database, National Institutes of Health (NIH), PubMed, Sage Journal, and SinceDirect. Based on the review that has been conducted, the use of gastritis drugs in the hospital has been rational based on the accuracy of the diagnosis, indications, drug selection, dosage, route of administration, awareness of side effects and assessment of the patient's condition.
REVIEW: KEPATUHAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI DIBEBERAPA RUMAH SAKIT DAN PUSKESMAS DI INDONESIA Ardiansyah, Muhamad; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1294

Abstract

Hipertensi merupakan penyakit yang umum ditemukan dalam kehidupan sehari-hari dan merupakan salah satu penyebab kematian di seluruh dunia. Komplikasi hipertensi dapat mengenai berbagai organ target, seperti jantung, otak, ginjal dan mata. Kerusakan organ tersebut bergantung pada tingginya tekanan darah pasien dan berapa lama tekanan darah tinggi tersebut tidak terkontrol dan tidak diobati. Artikel review ini bertujuan untuk mengidentifikasi tingkat kepatuhan minum obat antihipertensi pada pasien hipertensi dibeberapa Rumah Sakit dan Puskesmas di Indonesia. Metode yang digunakan adalah naratif literatur review melalui penelusuran 15 artikel dengan tahun penerbitan 2015-2024. Penelusuran literatur dilakukan pada database Google Scholar, PubMed, Research Gate dan ScienceDirect. Kata kunci yang digunakan pada penulusuran yaitu Antihipertensi, dan Medication adherence. Hasil tinjauan literatur ini menunjukan bahwa masih sangat rendah tingkat kepatuhan penggunaan obat antihipertensi pada beberapa Rumah Sakit dan Puskesmas yang ada di Indonesia dari 15 artikel yang dianalisis kepatuhan pasien hipertensi dibeberapa rumah sakit bervariasi dengan rata-rata kepatuhan tinggi 25,38%, kepatuhan sedang 27,14% dan kepatuhan rendah 49,50%, kepatuhan pasien hipertensi dibeberapa puskesmas dengan rata-rata kepatuhan tinggi 23%, kepatuhan sedang 31% dan kepatuhan rendah 46,6%. Kesimpulannya masih sangat banyak pasien hipertensi yang tidak patuh dalam minum obat, kepatuhan minum obat merupakan faktor utama keberhasilan terapi hipertensi. Untuk meningkatkan kepatuhan minum obat pasien hipertensi diperlukan peran penting Apoteker untuk mengintervensi, monitoring, dan juga meningkatkan pengetahuan pasien hipertensi guna tercapainya tekanan darah yang stabil
EVALUASI PENGGUNAAN OBAT PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS : NARATIVE LITERATURE RIVIEW Irawan, Wira; Sukandar, Elin Yulinah
Jurnal Buana Farma Vol. 5 No. 1 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i1.1327

Abstract

Chronic kidney failure is a condition characterised by a gradual deterioration of renal function over months to years, resulting in the replacement of normal cells by fibrous tissue, impairing the kidneys' ability to effectively filter waste products from the bloodstream. This review article is to examine medications that demonstrate effective therapeutic outcomes in accordance with treatment guidelines for patients with chronic renal failure, based on the criteria of appropriate patient, appropriate drug, appropriate indication, and appropriate dosage. The employed methodology is a narrative literature review, encompassing an examination of 14 papers published between 2015 and 2025. Literature searches were performed using the Google Scholar, PubMed, and Science Direct databases. The search employs the terms "Chronic Kidney Failure" and "Hemodialysis". The journal review indicates that pharmacological interventions in hospitalised chronic kidney failure patients aim to optimise renal filtration rates, avert the exacerbation of chronic kidney failure, and ameliorate physiological disturbances resulting from renal impairment. The hospital treatment adheres to the precision of diagnosis, indications, pharmacological selection, dosage, administration method, awareness of adverse effects, and evaluation of the patient's state in accordance with established therapeutic recommendations.
STUDI INTERAKSI OBAT-OBAT JANTUNG YANG DILAKUKAN TERHADAP ORANG SEHAT: TINJAUAN SISTEMATIS Sumartin, Yunita; Sukandar, Elin Yulinah
Kartika : Jurnal Ilmiah Farmasi Vol 9 No 2 (2024)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v9i2.669

Abstract

Patients with cardiovascular disease have a higher prevalence of drug interactions than other patient groups. Drug interactions may result from pharmacokinetic or pharmacodynamic mechanisms. This study is a systematic review that aims to identify drug interactions related to cardiac drugs. Article searches were conducted on PubMed and ScienceDirect databases to identify all articles on cardiac drug-drug interaction studies. The search started from articles published in 2013 to 2023. The keywords used in the article search were as follows: drug-drug interactions, cardiac patient, cardiac drug, cardiovascular drug, pharmacokinetics interaction, pharmacodynamic interaction combined with the boolean operator "AND". Study articles that met the requirements were entered into the study for review. The total number of articles identified from the database used was 805 articles; 7 duplicate articles were excluded; 84 articles were available in full text; but only 30 articles in accordance with the inclusion were reviewed. Potential drug interactions related to cardiac drugs were most common in the Angiotensin II Receptor Blocker (ARB) class of drugs. Other cardiac drug interactions occurred with angiotensin receptor-neprilysin inhibitors (ARNI), anticoagulants, antiplatelets, digoxin, calcium channel blockers and beta blockers. The effects of these cardiac drug interactions vary. To avoid the occurrence of drug interactions, co-administration of cardiac drugs should be administered with caution, dose adjustments may be required, and monitoring for possible adverse drug events should be done.
Co-Authors . Endarti . Patonah Afifah B. Sutjiatmo Afifah Bambang Sutjiatmo, Afifah Bambang Afrillia Nuryanti Garmana Afrillia Nuryanti Garmana Agung Yuwono Aisyah, Salmanda Ame Suciati Setiawan Anam, M. Khairul Ardiansyah, Muhamad Asep Abdul Rahman Asep Gana Suganda Asep Gana Suganda Asri Wulandari Astuti, Niken Juni Attifah Zahra Shafira Atun Qowiyyah Cahyono, Nur Sidik Candra candra Christanti, Yohanna Daryono Hadi Tjahjono Dwi Lestari Evi Sovia Faizal Hermanto Goeswin Agoes Hartini, Sri Hernandi, Baso Hikmat Permana Hubbi Nashrullah Muhammad I Ketut Adnyana Irawan, Wira Irda Fidrianny Irianti Bahana Maulida Reyaan Iwang Soediro Joseph I. Sigit Joseph Iskendiarso Sigit Joseph Iskendiarso Sigit Komar Ruslan Wirasutisna Kosasih Padmawinata Kuatrina, Kuatrina Kusmaningati, Suswini Kusmaningati, Suswini L Broto S Kardono Leni Herliani Afrianti Lucy Dewi N. Sasongko Marianne Marianne Maulita Cut Nuria Muhamad Insanu Muna Anom Fitri Narvikasari, Suci Neng Fisheri Kurniati Neng Fisheri Kurniati Nova Suliska Primal Sudjana Puput Ayu Perdana, Puput Ayu Putra , Erwin Ekadharma Putri, Mareta Ananda Raras Adinindya Putri Redya Hernawati, Redya Rini Syafriani Rini Syafriani Ririn Sinaga, Ririn Rizkita, Putri Rosnani Nasution RR. Ella Evrita Hestiandari Setiani, Nur Asni Setiawan, Finna Sheba, Shiane Hanako Siftiani, Nindy Dwi Siti Nur Aeni, Siti Nur Slamet Ibrahim - Soediro Soetarno Solihah, Puspa Sari Dewi Suci Nar Vikasari, Suci Nar Suganda, Asep Gana Sujiatmo, Afifah Bambang Sukrasno Sukrasno Sumartin, Yunita Sumintir, Sumintir Suryani Suryani Sylvia Sylvia Teti Indrawati Tommy Apriantono Vanessa Claudia Wiharja Vidya Finanda Yani Mulyani Yeyet Cahyati Sumirtapura Yulia Ratnawati, Yulia Yuliet Yuliet