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All Journal Jurnal Farmasi Udayana Farmaka Jurnal Matematika & Sains Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Jurnal Kimia Riset Jurnal Pengabdian Pada Masyarakat Pharmacology and Clinical Pharmacy Research JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung JURNAL FARMASI GALENIKA JFM (Jurnal Farmasi Malahayati) ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Pada Masyarakat International Journal of Health and Medicine Jurnal Farmasi Galenika Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine

Ellin Febrina

Farmasi Universitas Padjadjaran

Author-ID : 259157

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Peningkatan Potensi Anggota KWT dalam Pemanfaatan Pekarangan untuk Tanaman Obat dan Kosmetika Menggunakan Metode Tanam Vertikal di Desa Cibiru Wetan, Kabupaten Bandung Widhya Aligita; Fauzan Zein Muttaqin; Soni Muhsinin; Ellin Febrina; Aiyi Asnawi
Jurnal Pengabdian Pada Masyarakat Vol 4 No 4 (2019)
Publisher : Universitas Mathla'ul Anwar Banten

POTENTIAL DEVELOPMENT OF WOMAN FARMING GROUP IN THE UTILIZATION OF THE YARD FOR DRUG AND COSMETICS PLANTS USING VERTICAL GARDEN METHOD IN CIBIRU WETAN VILLAGE, BANDUNG REGENCY. The village of Cibiru Wetan is largely a rice field and swidden area with hilly contours and insufficient water availability. One of the utilization of fields with a lack of water is by growing plants that require minimal water, including medicinal plants and cosmetics. The initiation of this activity has a high prospect of success due to the high initiative and participation of the population in the form of women's farmer groups and the family welfare team as evidenced by the many achievements, awards, and skills gained by the Cibiru Wetan Village through the participation of its citizens. Therefore, the purpose of the project activity was socialization and practice at women’s farmer group of Cibiru Wetan Village through the use of medicinal plants and cosmetics with simple appropriate technology through vertical gardening. The method of implementation used in the training program for planting medicinal plants was divided two stage, that was providing information about family medicinal plants ranging from understanding to the benefits of the plants, and the last step was explaining or training and direct practice of planting medicinal plants and cosmetics using vertical planting. The results showed a positive understanding of the two groups of women’s farmer group I and II and the family welfare team, both for the stage of socialization and counseling as well as for the practice phase of planting medicinal plants and cosmetics vertically. The conclusion was the use of medicinal plants and cosmetics could increase the understanding of the target group and the compost produced by residents could be utilized through this activity.

Kemitraan Asosiasi Profesi Kesehatan dalam Aplikasi Metode KESET untuk Menangani Stress di Masa Pandemi Covid-19 bagi Masyarakat Desa Cibiru Wetan dan Praktisi Apoteker Kabupaten Sumedang, Jawa Barat Aiyi Asnawi; Widhya Aligita; Soni Muhsinin; Nur Intan Hayati Husnul Khotimah; Eki Pratidina; Iceu Mulyati; Yulianti Anjayani; Ellin Febrina; Fauzan Z Muttaqin
Jurnal Pengabdian Pada Masyarakat Vol 6 No 1 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202161.671

PARTNERSHIP OF THE HEALTH PROFESSIONAL ASSOCIATION IN THE APPLICATION OF THE KESET METHOD TO MANAGE STRESS DURING THE COVID-19 PANDEMIC FOR THE PEOPLE OF CIBIRU WETAN VILLAGE AND PHARMACIST PRACTITIONERS IN SUMEDANG REGENCY, WEST JAVA. EFT (Emotional Freedom Technique) is an alternative treatment method that offers healing from physical and emotional pain and disease. EFT works by tapping on acupressure meridians to release blockages. When these blockages are released, the problem feeling can be released and move through the body. Learning EFT also empowers the client to take charge of handling their emotional state/ controls stress. because they can tap on a feeling any time, they want to move out a painful feeling. Impact of quarantine or PSBB, the restriction of movement of people, is the mental health toll became even steeper including for community of Desa Cibiru Wetan and pharmacist of Kabupaten Sumedang, West Java. Therefore, the purpose of this community service activity was to transfer knowledge about the EFT method for stress management during the Covid-19 pandemic for the Desa Cibiru Wetan community and pharmacist in Kabupaten Sumedang, West Java. The stages of this activity began from education about stress and its prevention, and continues with the introduction of the KESET method in managing stress independently. The critical point in this activity is how to transfer knowledge and skills in preparing the participants who use this technique believe tapping the body can create a balance in their energy system and treat pain. The results of the activity showed that community participation could improve the knowledge and ability of participants in handling their emotional state/ controls stress by using KESET method. In conclusion, this activity could be an alternative healing from emotional pain for participants.

Peningkatan Potensi Ibu Rumah Tangga Peternak Sapi Perah dalam Membuat Yoghurt di Desa Cibiru Wetan, Kabupaten Bandung, Jawa Barat Aiyi Asnawi; Widhya Aligita; Soni Muhsinin; Eki Pratidina; Iceu Mulyati; Ika Kana Trisnawati; Ellin Febrina; Fauzan Zein Muttaqin
Jurnal Pengabdian Pada Masyarakat Vol 6 No 3 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202163.775

INCREASING THE POTENTIAL OF DAIRY CATTLE HOUSEWIVES IN MAKING YOGHURT IN CIBIRU WETAN VILLAGE, BANDUNG REGENCY, WEST JAVA. Yogurt is the product of milk fermentation by Lactobacillus subspecies. The unique properties of yoghurt provided by its living bacteria and its nutrients have captured the interest of the community. The highest price of cow's milk in dairy farming centres of Cibiru Wetan Village, Kabupaten Bandung is purchased by the Milk Processing Industry (IPS) at around IDR 4,500 / litre. Therefore, the purpose of this community service activity was the utilization of fresh cow milk as yoghurt to increase the income of dairy cattle farmer. Yoghurt processing begins with the modification of the incoming milk composition. This process typically involves reducing the fat content and increasing the total solids in the milk by are Lactobacillus bulgaricus and Streptococcus thermophilus. The stages of this activity began from providing an understanding of milk and dairy products and training in making yoghurt from fresh cow milk. The critical point in this activity is how to transfer knowledge and skills in preparing the starter and sterile conditions of the cooking utensils. The results of the activity showed that community participation could improve the knowledge and ability of participants in the processing of fresh cow milk as yoghurt. In conclusion, this activity could be an alternative income for dairy cattle farmer.

PENDIDIKAN KESEHATAN DENGAN METODE HYBRID TENTANG COVID-19 DAN PENYAKIT HIPERTENSI PADA KADER PKK DESA CIKIDANG KECAMATAN LEMBANG Jutti Levita; Sri Adi Sumiwi; Mutakin Mutakin; Tiana Milanda; Irma Melyani Puspitasari; Sriwidodo Sriwidodo; Ellin Febrina; Yasmiwar Susilawati; Indah Suasani Wahyuni; Irma Erika Herawati; Renny Amelia; Gofarana Wilar
Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Vol 11, No 2 (2022): Juni. 2022
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/dharmakarya.v11i2.34927

Kegiatan Pengabdian Kepada Masyarakat (PPM) di Desa Cikidang sudah dilaksanakan selama tiga tahun berturut-turut. Masyarakat berpartisipasi sangat baik dan menginginkan kegiatan dapat dilakukan secara kontinu serta melibatkan masyarakat yang lebih luas. Desa Cikidang belum memiliki sarana kesehatan dan lokasi Puskesmas terdekat adalah di Desa Cikole, berjarak 3,5 km. Berdasarkan data dari Puskesmas Cikole periode tahun 2019, tercatat bahwa penyakit hipertensi memiliki angka kejadian tertinggi yaitu 135 kejadian. Kegiatan PPM ini bertujuan untuk meningkatkan pemahaman kader PKK tentang penyakit hipertensi dan juga tentang COVID-19. Kegiatan dilakukan dengan menerapkan metode hybrid luring dan daring (gabungan sinkronus dan asinkronus menggunakan media leaflet dan video). Dari sejumlah enam puluh undangan yang disebarkan, kegiatan PPM dihadiri oleh tiga puluh lima peserta. Hasil pre-test dan post-test menunjukkan adanya peningkatan pengetahuan peserta, sehingga dapat disimpulkan bahwa pendidikan kesehatan secara hybrid berhasil meningkatkan pengetahuan kader PKK tentang COVID-19 dan Penyakit Hipertensi sebesar 13,56%.Â

ATR-FTIR Method for Detection of Cassava Impurities in Indonesian Commercial White Pepper (Piper nigrum L.) Based on Principal Component Analysis Aiyi Asnawi; Ajeng Fitriani; Ellin Febrina; Emma Emawati
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 2 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i2.24664

White pepper (Piper nigrum L.) is one of the most popular flavourings targeted for adulteration, i.e., cassava, resulting in quality loss and infringement on consumer rights and interests. Because it is easy and quick cleanup, minimal sample preparation, and excellent performance with strongly or thickly absorbed samples, the Attenuated Total Reflection-Fourier Transform Infrared Spectroscopy (ATR-FTIR) spectrum signal is widely used to measure commercial herbal products. Manipulation of the spectrum signal can be used to quantify a sample as well as reduce its dimensionality. As a result, there is a lot of interest in developing methods for detecting cassava in commercial white pepper (Piper nigrum L.). The aim of the research was to get an ATR-FTIR spectroscopic technique combined with chemometrics to detect cassava as an adulterant in commercial white pepper (Piper nigrum L.). The chemical profiles of white pepper (Piper nigrum L.) and cassava were compared using principal component analysis (PCA). Bangka, Sudu, and Pontianak were used to collect white pepper (Piper nigrum L.) and cassava. White pepper (Piper nigrum L.) and cassava were macerated in 96 percent ethanol for 3×24 hours before being concentrated with a rotary evaporator until thick. Each extract's IR spectral was measured using ATR-FTIR spectroscopy in the 4000-650 cm-1range. In addition, the IR spectral was clustered using PCA in the R program. To obtain the appropriate PCA model, we applied two IR spectral manipulation procedures (normal and derivative IR spectra) of the pure material. The PCA chosen was of the normal IR spectral type, with PC1 and PC2 values of 82.3 percent and 7.5 percent, respectively.. The projection of three commercial samples from the markets revealed that samples A and B were negative for cassava adulterant, while Sample C was suspected to be positive. Finally, the ATR-FTIR spectroscopic method tandem PCA was successful in clustering the presence or absence of cassava content in the commercial of Indonesian White Pepper

Peningkatan Kesiapsiagaan Kader PKK Cibiru Wetan untuk Ketahanan Bencana di Masa Pandemi COVID-19 Nur Intan Hayati Husnul Khotimah; Fauzan Zein Mutaqin; Soni Muhsinin; Widhya Aligita; Eki Pratidina; Iceu Mulyati; Yulianti Anjayani; Untung Sudharmono; Etika Emaliyawati; Ellin Febrina; Aiyi Asnawi
Jurnal Pengabdian Pada Masyarakat Vol 7 No 2 (2022): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

IMPROVİNG THE PREPAREDNESS OF CİBİRU WETAN PKK CADRES FOR DİSASTER RESİLİENCE DURİNG THE COVİD-19 PANDEMİC. Cibiru is a high-risk area for natural and man-made disasters, so efforts must be made to reduce the risk of disaster impacts. One effort that can be made is to strengthen the Cibiru Wetan village's resilience by increasing preparedness to deal with emergency cases caused by disasters, such as cases of respiratory arrest, cardiac arrest, trauma, and respiratory emergencies caused by COVID-19. Community service is performed to improve the preparedness of Cibiru Wetan PKK cadres for disaster-resilient village resilience during the COVID-19 Pandemic. The method of implementing community service by simulating basic life support, trauma event handling, prevention and handling of COVID-19 emergencies, and the production of health drinks made from natural ingredients such as ginger, honey, lime, cardamom, and turmeric to boost immunity. As a result, the Cibiru Wetan PKK cadres were able to simulate basic life support, first aid in the event of trauma, and respiratory disorders caused by COVID-19, as well as process natural ingredients into healthy drinks to increase immunity, thereby increasing the Cibiru Wetan village's resilience.

Penambatan Molekul dan Dinamika Molekul beberapa Fitokimia dari Acalypha Indica L. sebagai Inhibitor Matriks Metalloproteinase9 Aiyi Asnawi; Ellin Febrina; Widhya Aligita; Anne Yuliantini; Arfan Arfan
Jurnal Sains Farmasi & Klinis Vol 10, No 1 (2023): J Sains Farm Klin 10(1), April 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.1.62-70.2023

Berbagai efek farmakologis telah dikaji terhadap ekstrak dan islolat dari Acalypha Indica L. terutama terkait dengan aktifitas anti kanker. Matrix metalloproteinases MMP9 merupakan contoh yang sangat baik dari kelompok proteinase terpenting yang terlibat dalam sel metastatic/kanker. MMP9 telah dikaitkan dengan berbagai macam penyakit, termasuk sistem pernapasan, sistem autoimun, dan bahkan kanker. Maka dari itu, makalah ini bertujuan untuk mendapatkan senyawa pemandu dari beberapa fitokimia Acalypha Indica L. yang bertanggung jawab dalam migrasi sel dengan menggunakan penambatan molekul dan dinamika molekul. Ligan ditambatkan ke situs aktif struktur kristal MMP9 (PDB ID: 5UE4) menggunakan aplikasi AutoDock Release 4.2.6. Proses penambatan molekul divalidasi dengan melakukan penambatan ulang ligan alami pada sisi aktif MMP9. Selanjutnya, menggunakan GROMACS dilakukan simulasi dinamika molekul (MD) ditandem dengan algoritma gmx_MMGBSA dan gmx_MMGBSA_ana untuk menghitung energi ikatan dan kontribusi residu terhadap terhadap kestabilan kompleks. Hasil menunjukkan hanya satu ligan dari 36 ligan yang dievaluasi tidak mampu berikatan dengan sisi aktif MMP9, dan enam dari ligan mampu mengikatnya lebih negatif daripada ligan alami. Kompleks dengan ligan S54 dan S56 yang memiliki energi paling negatif tetapi dari sisi parameter lainnya, kompleks S56 paling stabil. Dapat disimpulkan, g-sitosterol asetat (S56) memiliki potensi untuk berfungsi sebagai senyawa pemandu untuk MMP9

Potensi Senyawa Aktif Tanaman Herbal untuk Pengobatan Kanker Payudara dengan Metode Penambatan Molekuler: Review Artikel Alma Yunita Sari; Ellin Febrina
Jurnal Farmasi Udayana Vol. 12, No 1, Tahun 2023
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2023.v12.i01.p04

Breast cancer is one of the leading causes of death in women worldwide. Breast cancer can be triggered due to physical, chemical, environmental factors and can be passed down from generation to generation through genetics. Therefore, recently, studies have been intensively conducted on the use of medicinal plants for the treatment of breast cancer as an alternative because they have minimal side effects compared to other chemotherapy. This review aims to describe medicinal plants and their active compounds that have the potential as anticancer therapy which has been carried out in silico studies with molecular anchoring methods. The method used in writing this article is a literature review both nationally and internationally over the last five years using the keywords breast cancer, molecular docking, herbal plants, anticancer, in databases such as PubMed, Cochrane, and Google Scholar. Herbal plants in in silico research that have high potential for further research as cancer therapy include 33 herbal plants with different active compounds and protein targets.

Review Artikel: Spironolakton Sebagai Obat Off-Label Untuk Jerawat Pada Wanita Dewasa Zulfa, Aulia; Febrina, Ellin
Farmaka Vol 21, No 3 (2023): Farmaka (November)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v21i3.47905

Jerawat merupakan penyakit kulit yang umum terjadi pada remaja dan dewasa. Jerawat dewasa dapat berupa jerawat persisten (jerawat dari sejak remaja) atau onset (jerawat muncul >25 tahun). Prevalensi jerawat dewasa paling banyak terjadi pada wanita dibandingkan laki-laki. Peningkatan produksi sebum menjadi salah satu faktor terjadinya jerawat. Spironolakton sebagai obat anti-adrenergik memiliki efek antagonis reseptor androgen dengan mekanisme inhibisi reseptor androgen secara kompetitif dengan dihidrotestosteron untuk menurunkan produksi sebum. Penggunaan spironolakton untuk jerawat masih tergolong obat off-label. Obat off-label merupakan obat yang digunakan untuk pengobatan gejala klinis tetapi tidak sesuai dengan informasi obat yang disetujui oleh Food and Drug Administration (FDA) atau Badan POM. Penulisan artikel ini bertujuan untuk mengetahui efektifitas dan rentang dosis bagi spironolakton untuk terapi jerawat pada pasien Wanita dewasa. Artikel ini berupa kajian naratif dengan menggunakan database SpringerLink, PubMed dan ScienceDirect dengan kata kunci spironolactone dan acne dari 2013-2023. Hasilnya, beberapa penelitian menunjukkan bahwa spironolakton efektif dan dapat memberikan perbaikan klinis pada jerawat dengan pemberian dosis rendah (50-100 mg/hari). Pematauan serum kalium juga diperlukan untuk menjegah terjadinya efek samping hiperkalemia.

PENETAPAN KADAR PSEUDOEFEDRIN HCL DAN LORATADIN DALAM KOMBINASI SEDIAAN KAPSUL MENGGUNAKAN METODE KLT VIDEO DENSITOMETRI aiyi asnawi; Ellin Febrina; Deden Indra Dinata; Farizan Nur Fazrina
JURNAL FARMASI GALENIKA Vol 4 No 3 (2017): Jurnal Farmasi Galenika Volume 4 No. 3, 2017
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Sediaan pseudoefedrin HCl dan loratadine tersedia di perdagangan dalam bentuk kombinasi campuran. Sediaan yang berupa campuran, memerlukan metode analisis dengan perlakuan lanjut sebelum dilakukan pengukuran dikarenakan adanya perbedaan sifat farmakokimia dari zat yang terkandung di dalamnya. Oleh sebab itu diperlukan metode analisis yang akurat, jika memungkinkan sederhana dan murah, untuk menganalisis kandungan sediaan kombinasi tersebut. Salah satu metode yang sederhana yang mampu memberikan hasil yang akurat adalah KLT video densitometri. Tujuan dari penelitian ini untuk memvalidasi metode dalam menetapkan kadar pseudoefedrin HCl dan loratadine dalam sediaan kapsul menggunakan metode KLT video densitometri. Tahapan penelitian meliputi uji kesesuaian sistem menggunakan fase diam plat silika gel GF254 dan fase gerak campuran pelarut metanol-amonia (10mL : 4 tetes, v/v); validasi metode analisis, dan penetapan kadar dalam sediaan yang beredar di pasar. Perekaman gambar dilakukan dibawah lampu UV 255nm menggunakan alat video densitometri dan pengukuran luas dibawah kurva (AUC) dari gambar bercak menggunakan perangkat lunak TLC Analyzer. Penotolan sampel dilakukan secara manual menggunakan pipa kapiler. Hasil pengujian uji kesesuaian sistem diperoleh nilai Rf pseudoefedrin HCl dan loratadine berturut-turut adalah 0,35 dan 0,84. Persamaan kurva kalibarasi untuk pseudoefedrin HCl dan loratadine berturut-turut adalah Y = 0,3003X â€“ 715,94 dan Y = 6,8705X + 222,86. Setelah semua parameter validasi memenuhi persyaratan, diperoleh persen kadar pseudoefedrin HCl dan loratadine dalam sediaan kapsul berturut-turut adalah sebesar 99,42% dan 101%, memenuhi syarat yang ditetapkan dalam Farmakope Indonesia. Nilai-nilai parameter validasi tersebut memenuhi syarat yang telah ditetapkan sehingga metode KLT video densitometri layak untuk digunakan.

Co-Authors ABDUR RACHMAN Abdurahman Ridho Achmad Zaenudin Ade Zuhrotun Ahmad Muhtadi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Aiyi Asnawi Ajeng Fitriani Aligita, Widhya Aliya Nur Hasanah Alma Yunita Sari Ami Rahmati Syadiah Ami Tjitraresmi, Ami Aminah Nurhadiyah Anas Subarnas Andriansyah, Ivan Anis Yohana Chaerunisaa Anne Yuliantini Annisa Desy Aryanti Arfan Arfan Arfan Arfan Cindy Ivana Putri Daffa Anjabtsawa Dana Nasrullah Deden Indra Dinata Deden Indra Dinata, Deden Indra Destiani, Dika P. Devi Rahmawati Dewi Kurnia Dika Destiani Dika P. Destiani Eki Pratidina Eli Halimah, Eli Emma Emawati, Emma Erli Berlianti Etika Emaliyawati Farizan Nur Fazrina Fauzan Z Muttaqin Fauzan Zein Mutaqin Fauzan Zein Muttaqin Fikri Nazaruddin Ghozaly, Muchammad R. Gofarana Wilar Herawati, Irma E. Iceu Mulyati Iceu Mulyati Ika Kana Trisnawati Ilahi, Ade Rezki Indah Suasani Wahyuni Irma Erika Herawati Irma M. Puspitasari, Irma M. Irma Melyani Puspitasari Irma Meylani Puspitasari Ivan Andriansyah Ivan S. Pradipta Jutti Levita La Ode Aman Marline Abdassah MEGA HIJRIAWATI Muchammad R. Ghozaly Muhammad H. Ridwan Mutakin Mutakin Muttaqin, Fauzan Zein Naja, Syahrul Nur Intan Hayati Husnul Khotimah Nur Intan Hayati Husnul Khotimah Nurhadiyah, Aminah Nursamsiar Nursamsiar Pradipta, Ivan S. Priskila, Miranda PUTY PRIANTI NOVIRA Ramadaini, Tiara Rani Ratnawati Ratnawati, Rani Renny Amelia Ridwan, Muhammad H. Riezki Amalia Rika Rendrika Rini Hendriani Rusdianto, Aziiz M. Septian Riyadi Silviana, Lilis Sitti Rahmi Soni Muhsinin Sri Adi Sumiwi Sriwidodo Sriwidodo Sumiwi, Sri A. Syadiah, Ami Rahmati Syahrul Naja TIANA MILANDA Ulfinana Hafni Untung Sudharmono Wahyuni, Indah S. Wayan Ayu Puje Astuti Widhya Aligita Widhya Aligita Widhya Aligita Yasmiwar Susilawati Yuli Andriani Yulianti Anjayani Yulianti Anjayani Yuliantini, Anne Zaenudin, Achmad Zulfa, Aulia

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