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All Journal Jurnal Gizi dan Pangan MEDIA MEDIKA INDONESIANA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Andalas The Indonesian Biomedical Journal Sari Pediatri Padjadjaran Journal of Dentistry Paediatrica Indonesiana Jurnal Kesehatan Reproduksi Jurnal Ipteks Terapan Journal of Midwifery Majalah Kedokteran Andalas Jurnal Ners pendidikan, science, teknologi, dan ekonomi Andalas Dental Journal Cakradonya Dental Journal

Fadil Oenzil

Fakultas Kedokteran Universitas Andalas

Author-ID : 262562

Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences

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HUBUNGAN KEBIASAAN MEROKOK DENGAN DERAJAT KEASAMAN (pH) SALIVA PADA MAHASISWA JURUSAN TEKNIK SIPIL ANGKATAN 2010 FAKULTAS TEKNIK UNIVERSITAS ANDALAS Murniwati .; Fadil Oenzil; Idson Kamal; Minarni .
Cakradonya Dental Journal Vol 9, No 2 (2017): Desember 2017
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v9i2.9745

Saliva merupakan cairan biologis pertama yang terpapar oleh asap rokok di rongga mulut. Asap rokok mengandung berbagai macam zat kimia yang dapat menyebabkan perubahan struktural dan fungsional pada saliva. Penelitian ini bertujuan untuk mengetahui hubungan antara kebiasaan merokok dengan derajat keasaman (pH) saliva. Desain penelitian ini adalah Cross Sectional Study dengan sampel 48 mahasiswa jurusan Teknik Sipil angkatan 2010 Fakultas Teknik Universitas Andalas. Data kebiasaan merokok didapat melalui kuesioner dan pH saliva diukur menggunakan dental saliva pH indikator. Analisa data menggunakan Chi-Square dengan =0,05. Penelitian menunjukkan jenis rokok yang dikonsumsi adalah rokok putih (75%) dengan konsumsi per hari sebanyak 5-14 batang (54,2%). Responden telah mengkonsumsi rokok secara rutin selama lebih dari 4 tahun (37,2%). Sebagian besar responden memiliki pH saliva berkategori asam (52,1%). Tidak terdapat hubungan yang bermakna antara jenis rokok yang dikonsumsi dengan pH saliva ( p0,05 ). Terdapat hubungan yang bermakna antara tipe perokok dengan pH saliva ( p0,05 ) dan antara lama periode merokok dengan pH saliva (p0,05). Terdapat hubungan antara tipe perokok dan lama periode merokok dengan derajat keasaman (pH) saliva. Tidak terdapat hubungan antara jenis rokok dengan derajat keasaman (pH) saliva.Kata Kunci: Saliva, merokok, derajat keasaman

EFIKASI SUPLEMENTASI FORMULA TEMPE BENGKUANG TERHADAP KADAR ALBUMIN DAN Z-SKOR BERAT BADAN MENURUT UMUR (BB/U) PADA ANAK GIZI KURANG Symond, Denas; Oenzil, Fadil; Darwin, Eriyati; Lipoeto, Nur Indrawati
Jurnal Gizi dan Pangan Vol. 11 No. 1 (2016)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

The aim of this study was to determine the efficacy of formulated tempe-yam supplementation on weight for age z-score of underweight children aged 2-4 years. A quasi experiment pre-post test with control group design was applied in this study for four weeks. The intervention group consist of 19 children given formulated tempe-yam 100 g/d; and the control group consist of 19 children given biscuit 100 g/d in Padang Pariaman district, West Sumatera. Data collected included weight, height, and albumin level. Paired t-test was applied for the data analysis. The results of this study found significant differences in albumin level before and after on control group (p<0.05). Then, the results of this study also found significant differences in weight for age z-score before and after on intervention group (p<0.05). Therefore, formulated tempe-yam supplementation as food sumplementation need to be considered for underweight children.Keywords: albumin level, food suplementation, tempe-yam, weight-for age z-score

Pengaruh Likopen terhadap Kadar Soluble FMS-Like Tyrosine Kinase 1 pada Preeklamsi Basyir, Vaulinne; Fauziah, Prima Nanda; Pramatirta, Akhmad Yogi; Yanwirasti, Yanwirasti; Mose, Johanes C.; Oenzil, Fadil
Jurnal Kesehatan Andalas Vol. 9 No. 4 (2020): Online December 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i4.1513

Preeklamsi merupakan penyebab utama morbiditas dan mortalitas baik maternal maupun perinatal. Tujuan: Menganalisis pengaruh pemberian likopen terhadap kadar sFlt-1 secara in vitro pada sel trofoblas model preeklamsi. Metode: Penelitian ini dilakukan secara eksperimental di Laboratorium Genetika Molekuler dan Kultur Sel Fakultas Kedokteran Universitas Padjadjaran selama periode 2017-2018. Sampel serum diperoleh dari RS. Dr. Hasan Sadikin Bandung, sesuai kriteria inklusi dan eksklusi. Kriteria inklusi adalah pasien yang telah didiagnosis preeklamsi berdasarkan pemeriksaan tekanan darah dan protein urin, dan kriteria eksklusi adalag pasien yang tidak datang kontrol atau tidak bisa dihubungi. Penelitian ini terdiri dari dua tahap, pertama ditentukan nilai LD50 likopen terhadap sel trofoblas kemudian dijadikan dasar nilai konsentrasi yang akan digunakan, selanjutnya dilakukan pemeriksaan sFlt-1 menggunakan metode Elisa pada kultur sel trofoblas kondisi normal dan preeklamsi dengan analisa data menggunakan analisis varians (Anova) dan uji Duncan untuk mengetahui perbedaan antar variabel. Hasil: Nilai LD50 adalah 250 ug/ml dan serial konsentrasi yang digunakan mulai dari 1,953 sampai dengan 125 ug/ml. Didapatkan kadar sFlt-1 menurun secara signifikan (p0,05) dari 39,5445 menjadi 31,1342 pg/ml pada sel trofoblas yang diinduksi dengan serum preeklamsi setelah pemberian konsentrasi likopen sebesar 15,625-31,25 ug/ml yang nilainya mendekati keadaan pada sel trofoblas yang diinduksi serum kehamilan normal. Pemberian likopen dapat menurunkan kadar sFlt-1 pada sel trofoblas preeklamsi. Simpulan: Likopen dapat merubah kadar sFlt-1 dan perubahannya dipengaruhi oleh konsentrasi dan jenis serum.Kata kunci: likopen, preeklampsi, sFlt-1Â

Differences between dental health service quality and utilization of Community Health Centres in the City of Padang based on indicators of utilisation effectiveness Darma, Azri; Hidayati, Hidayati; Oenzil, Fadil
Padjadjaran Journal of Dentistry Vol 30, No 2 (2018): July 2018
Publisher : Universitas Padjadjaran

Introduction: The high prevalence of oral disease have not been followed by the availability of oral healthcare, especially at the community-based level. This study was aimed to determine the differences between dental health service quality and utilisation of community health centres in the city of Padang based on indicators of utilisation effectiveness. Methods: A cross-sectional survey was conducted towards two Community Health Services (Puskesmas) as the samples selected using random sampling technique. One Community Health Service was representing a rarely visited Community Health Service with ≤ 9 patients visit per day, and another Community Health Service was representing oppositely. As much as 131 respondents were included in this study, selected using the purposive sampling method. Dimensional satisfaction of service quality including tangibility, reliability, responsiveness, assurance, and empathy, were collected by interviewing the respondents based on a self-reported questionnaire. All data were analysed using the chi-square test. Results: The majority of respondents agreed that dimensional satisfaction such as tangibility, reliability, responsiveness, assurance, and empathy at both Community Health Services were at a good level. There was a significant relationship (p < 0.05) between several dimensional satisfaction of service quality variables (the wide and clean parking area; intense involvement of dentists on every oral examination; friendly service by the front-office; and empathetic affection of dentists towards the patient’s complain) and the utilisation of oral health services. Conclusion: No service differences found from relationship analysis between dental health service quality and utilisation of community health centres in the city of Padang based on indicators of utilisation effectiveness.Keywords: Service quality, dimensional satisfaction, oral health service, service utilisation, Community Health Centre.

The effect of pasteurized milk and pure soy milk on enamel remineralization Metly, Annesha; Sumantri, Dedi; Oenzil, Fadil
Padjadjaran Journal of Dentistry Vol 31, No 3 (2019): November 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no3.22833

Introduction: Tooth remineralization agent can be found in pasteurized milk and soy milk. Ca2+ and PO43- ions concentration in both products inhibited hydroxyapatite dissolution and enhanced remineralization. This study was aimed to investigate the effect of pasteurized milk and pure soy milk on tooth enamel remineralization. Methods: This study was an experimental laboratory with pre-test post-test control group design. Twenty-seven maxillary premolars were divided into 3 groups; 37% phosphoric acid used to demineralized the samples followed by initial enamel hardness measurement. All samples were immersed in aquadest, pasteurized milk, and pure soy milk for 14 days, 102 minutes per day. Final enamel hardness was measured with the Vickers hardness test. Results: Increasing enamel hardness was found in all groups. Two-way ANOVA test was used to compare the increase of enamel hardness in all group, which showed the p-value = 0.002. Post-hoc LSD test was then used to compare the increase of the enamel hardness in pasteurized milk and pure soy milk groups, which resulted in the p-value = 0.147. Conclusion: There was an effect of pasteurized milk and pure soy milk group on enamel remineralization. However, there was no difference in the increase of enamel hardness value between pasteurized milk and pure soy milk groups.Keywords: Pasteurized milk, pure soy milk, tooth enamel, remineralization.

HUBUNGAN PERSEPSI DENGAN TINGKAT KEBUTUHAN PERAWATAN ORTODONTI BERSADASARKAN DENTAL AESTHETIC INDEX THE RELATIONSHIP BETWEEN PERCEPTION WITH THE NEED OF ORTHODONTIC TREATMENT BASED ON DENTAL AESTHETIC INDEX K, Didin; Oenzil, Fadil; Lathiva, Muthia
Cakradonya Dental Journal Vol 14, No 1 (2022): Februari 2022
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v14i1.19504

Dental Aesthetic Index merupakan salah satu indeks yang memiliki fungsi untuk menilai kebutuhan perawatan ortodonti suatu individu.Tujuan penelitian ini adalah untuk mengetahui gambaran persepsi dan tingkat kebutuhan perawatan ortodonti serta hubungan persepsi dengan tingkat kebutuhan perawatan ortodonti berdasarkan Dental Aesthetic Index pada mahasiswa Fakultas Kedokteran Gigi Universitas Andalas.Penelitian menggunakan desain cross sectional. Subjek penelitian adalah Mahasiswa Fakultas Kedokteran Gigi Universitas Andalas umur 18-21 tahun berjumlah 28 orang yang dipilih berdasarkan teknik Purposive Sampling. Kebutuhan perawatan ortodonti dinilai dengan pemeriksaan model studi menggunakan Dental Aesthetic Index dan persepsi kebutuhan dinilai menggunakan kuesioner yang telah dilakukan uji validitas (Pearson Product Moment). Data dianalisis menggunakan uji Spearman Rank Correlation. Hasil penelitian menunjukkan mahasiswa yang memiliki persepsi baik 20 orang (71,4%) dan persepsi tidak baik 8 orang (28,6%). Hasil untuk tingkat kebutuhan perawatan ortodonti didapatkan 16 orang (57,1%) tidak/sedikit membutuhkan perawatan, 7 orang (25%) perawatan elektif, 3 orang (10,7%) sangat membutuhkan perawatan dan 2 orang (7,1%) wajib mendapatkan perawatan. Hasil Penelitian menunjukkan terdapat hubungan yang signifikan (p0,05) antara persepsi dengan tingkat kebutuhan perawatan ortodonti berdasarkan Dental Aesthetic Index dengan koefisien korelasi sebesar 0,446.Kesimpulan dari penelitian ini adalah Sebagian besar Mahasiswa Fakultas Kedokteran Gigi Universitas Andalas memiliki persepsi baik dan kebutuhan perawatan ortodonti dalam kategori perawatan tidak/ sedikit membutuhkan perawatan serta terdapat hubungan yang signifikan antara persepsi dengan tingkat kebutuhan perawatan ortodonti berdasarakan Dental Aesthetic Index pada mahasiswa fakultas kedokteran gigi Universitas Andalas.

Serum Prolactine Levels and Prolactine Receptor Expression in Premenopausal Breast Cancer: A Potential Predictive Biomarker? Tripriadi, Effif Syofra; Maulanisa, Sinta Chaira; Lipoeto, Nur Indrawati; Yanwirasti, Yanwirasti; Oenzil, Fadil; Harahap, Wirsma Arif; Utami, Tania Nugrah; Mardhiyah, Farah
Jurnal Ners Vol. 10 No. 1 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.52299

Introduction: Premenopausal breast cancer (PBC) is often more aggressive than postmenopausal cases, with prolactin playing a key role in tumor development. This study examines the relationship between serum prolactin levels, prolactin receptor (PRLR) expression, and clinicopathological features in PBC patients. Methods: This cross-sectional study was conducted from 2021 - 2022 at multiple hospitals in Pekanbaru, Indonesia. Thirty-five PBC patients and 35 healthy controls were included. Serum prolactin levels were measured using ELISA, and PRLR expression was assessed via IHC. Statistical analysis was performed using independent t-tests and correlation analysis (p < 0.05). Results: PBC patients had higher prolactin levels (51.96±80.40 ng/mL) than controls (20.83±15.74 ng/mL, p = 0.031). PRLR expression was detected in over 90% of tumors, with a significant correlation between prolactin levels and cancer stage (p = 0.035). Discussion: These findings suggest prolactin contributes to PBC progression, with higher levels linked to advanced stages, possibly through JAK2/STAT5 signaling. Conclusion: Serum prolactin levels and PRLR expression are associated with cancer stage, supporting their potential as biomarkers for early detection and disease progression. Further studies are needed for validation.

Co-Authors Akhmad Yogi Pramatirta, Akhmad Yogi Aldian Mulyanto Lokaria Amel Yanis Amirah Zatil Izzah Aria Fransiska Arni Amir Asterina Asterina Basyir, Vaulinne Darma, Azri Darma, Azri Deddy Satriya Putra Delmi Sulastri Denas Symond Desmawati Desmawati Desmiwarti Desmiwarti Detty Iryani Dia Rofinda, Zelly Dia Dian Pertiwi Didin Kustantiningtyastuti Dini Noviarti Dona Mirsa Putri Effif Syofra Tripriadi, Effif Syofra Efrida Efrida Eka Agustia Rini Endrinaldi Eriyati Darwin, Eriyati Erlina Rustam Eryati Darwin Eti Yerizel Eva Chundrayetti Fadma Yuliani Fasli Jalal Feby Ramadhani Fido Arif Firman Arbi Gusti Revilla Gustina Lubis Gustina Lubis Hafni Bachtiar Hannie Qalbina Syaiful Harsa Rusda Havis Dharma Rafke Hidayati Hidayati Hidayati Hidayati Ibrahim Ibrahim Idson Kamal Iskandar Syarif Ismawati Ismawati Johanes C. Mose Johanes C. Mose Julispen Syafruddin Muhi K, Didin Lathiva, Muthia Laura Kosasi Lisbet Rimelfhi Sebataraja Mardhiyah, Farah Maulanisa, Sinta C. Medika Prasetya Meiyestri Dwi Riani Metly, Annesha Mia Puspita Miharti, Sari Ida Minarni Minarni Muhamad Febry Muhammad Ridwan Murniwati . Murniwati Murniwati Muthia Lathiva Nidia Purwadianti Nila Kasuma Novia Susanti Nur Indrawati Lipoeto Nur Indrawaty Liputo Nurul Fadila Pagdya Haninda Nusantri Rusdi Pipit Amelia Burhani Prima Nanda Fauziah Putri Auliya Putri Yuriandini Yulsam Reni Puspita Riani Hafiza Rudy Afriant Sari Ida Miharti Siti Lestari Sumantri, Dedi Syarif, Iskandar Tofrizal Trisna Resti Yanti Usna Maria Harahap Utami, Tania Nugrah Vaulinne Basyir Wirsma Arif Harahap Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yelvi Novita Roza Yenita Yenita Yerizal Karani Yusri Dianne Jurnalis Yustini Alioes Zul Febrianti

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