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AKTIVITAS FISIK AKUT INTERVAL DAN KONTINYU INTENSITAS MODERAT TIDAK DAPAT MENURUNKAN KADAR BIOMARKER RESORPSI TULANG CTx Triardhana, Yanuar Alfan; Sari, Gadis Meinar; Liben, Paulus
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 2 (2021): EDITION JULY 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i2.1510

Abstract

Physical activity will affect the bone remodeling process and have an impact on bone health. Physical activity would activate osteoblasts and precursor through lane HPA Axis to start the process of bone remodeling. When the process of remodeling of bone occurs there are molecules of collagen which is released into the circulation, i.e. CTx (osteoclast marker). The aim of this study to showing effect of acute continuous and interval physical activity with moderate intensity on CTx. This research was using the type of research field experimental by using the pretest-posttest design. Sixteen adult male was selected on this study and devided into 2 with 8 people every group. Blood sample was taken before and 1 hour after the physical activity. The results obtained showed the acute effect of continuous physical activity with moderate intensity to CTx with a mean pretest 0,93 ± 0,566 posttest 0,559 ± 0,398 ng/mL (p = 0.173 0.05), acute effect of moderate intensity interval physical activity on CTx with the mean pretest 0,451 ± 0,302 posttest 0,524 ± 0,284 ng/mL (p = 0.693 0.05). From this study can be concluded that there was no effect of acute continuous and interval physical activity with moderate intensity on CTx. 
KARAKTERISTIK DISMENORE PADA PASIEN ENDOMETRIOSIS DI RSUD DR. SOETOMO SURABAYA Ariviani, Fauziah; Annas, Jimmy Yanuar; Sari, Gadis Meinar
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 9, No 1 (2021): EDITION MARCH 2021
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v9i1.2064

Abstract

ABSTRACT Endometriosis is a disordered growth of the endometrial glands outside the uterus that often affects women of reproductive age. Endometriosis could reduce the quality of life and prone to bear the infertility. The most common symptom is dysmenorrhea, and this is often times misunderstood by most of women who thought menstruating women commonly experienced this. The purpose of the research is to determine the characteristics of dysmenorrhea in endometriosis patients. This research was an observational study by conducting direct interview with patients and analyzing descriptively. There are 42 respondents in this research, the highest frequencies in variable were as follows: age diagnosed is 30-39 years (42.8%), age of dysmenorrhea onset is 2 days (66.7%), pain intensity on a scale of 8 (33.3%), and the pain description is like squeezing (61.9%). In this research the average delay in diagnosis of endometriosis for 10.6 years, patients begin experiencing dysmenorrhea during menstruation for more than two days, the pain intensity of dysmenorrhea is on a scale of 8, and the pain description is like squeezing.
The Relationship of Early Providing MPASI and Recurrent Infectional Diseases with Stunting Incidents in Children Aged 1-5 Years in the Lawahing Public Health Care Working Area Fitria Amin, Nurhayati; Meinar Sari, Gadis; Gita Ningrum, Astika
Jurnal sosial dan sains Vol. 4 No. 1 (2024): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsosains.v4i1.1196

Abstract

Background: Stunting which is a condition where there is failure to thrive in children under five years old (under five years) caused by chronic malnutrition so that the child is too short for his age. Providing complementary breast milk too early (less than 4 months) is an indirect factor causing stunting where early complementary breast milk food can cause various kinds of infectious diseases in children Purpose: to determine the relationship between giving early MPASI and recurrent infectious diseases to the incidence of stunting in children aged 1-5 years in the working area of the Lawahing Health Centre, Alor Regency, NTT Method: This research is an observational analytical study with a cross sectional approach. The sample from this study was 214 children aged 1-5 years who met the inclusion and exclusion criteria. Results: : research shows that there is a significant relationship between early complementary feeding and recurrent infectious diseases and the incidence of stunting in children aged 1-5 years (p value: <0.01). Conclusion: there is a significant relationship between early complementary feeding and recurrent infectious diseases with the incidence of stunting in children aged 1-5 years in the working area of the Lawahing Community Health Centre, Alor Regency, East Nusa Tenggara.
Gambaran Tingkat Pengetahuan Ibu Hamil Tentang Pencegahan Penularan HIV pada Anak (PPIA) di Puskesmas Putat Jaya Kota Surabaya Hamidah, Nadhifa Alya; Setyowati, Dewi; Sari, Gadis Meinar
Jurnal Ilmiah Universitas Batanghari Jambi Vol 24, No 2 (2024): Juli
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v24i2.4867

Abstract

The proportion of HIV-positive pregnant women in Indonesia rises annually. Pregnant women’s HIV test results in Indonesia fall a little short of the target for 2022. Knowledge is one of the most important aspects of the prevention of mother-to-child transmission of HIV (PMTCT). The aim of this research is to determine the knowledge among pregnant women in Putat Jaya Community Health Care in Surabaya regarding the transmission of HIV from mothers to their children. Cross-sectional analysis is used in this descriptive study. There are 35 pregnant women who have responded. Mothers enrolled in trimesters 1, 2, and 3 who are getting antenatal care at Putat Jaya Community Health Care in Surabaya meet the inclusion criteria for this study. However, a mother with special needs is the sole requirement for this study. In September 2023, this study was carried out at Putat Jaya Community Health Care in Surabaya. The method for gathering samples is called purposive sampling. According to the findings, 77.1% were sufficiently aware of how to prevent HIV transmission from mother to child, followed by 14.3% who had high knowledge and 8.6% who had a lack of knowledge about the prevention of mother-to-child transmission (PMTCT) of HIV.
Early Stunting Detection Education as an Effort to Increase Mother's Knowledge about Stunting Prevention Sari, Gadis Meinar
Folia Medica Indonesiana Vol. 57, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Stunting is one of the main nutritional problems that is still common in children under five and has serious health impacts. The results of National Health Research (Riskesdas) in 2018 showed the prevalence of stunting at 30.8%, indicating that 1 out of 3 Indonesian children are still stunted. Probolinggo Regency is a priority area for stunting handling in 2019 with a prevalence of 50.2% according to a report from the National Team for the Acceleration of Poverty Reduction (TNP2K). One of the factors that directly affect the incidence of stunting is low birth weight (LBW), while the mothers' knowledge level of health is an indirect factor that affects the growth conditions of children under five. The purpose of this study was to analyze the effect of providing stunting early detection education on maternal knowledge regarding stunting prevention. This is a pre experimental research study with one group pre-post test design, children aged 0-24 months as the research subjects. The case group consisted of stunted children (BL/A <-2 SD Z-score), while the control group consisted of normal children according to the BL/U indicator. The number of research subjects for the case and control groups was 40 with mothers of the toddlers as research respondents. The samples were selected using total sampling technique. Data were analyzed using dependent T test and linear regression. The results suggested that at the beginning of the session before provided education about early detection of stunting, mothers with stunting toddlers had lower level of knowledge (73.3%) than those with normal toddlers (77%). After provided with education, the knowledge level of mothers with stunted toddlers appreared to be higher (89%) than those with normal children (87.6%), with significant increase in each group (P <0.05). It can be concluded that education on stunting detection can significantly improve mothers' knowledge regarding the prevention of stunting in children aged 0-24 months. Providing regular education, both by nutrition workers at the health center and integrated service post (posyandu) cadres, is necessary as an effort to prevent stunting to the maximum.
Correlation of Mothers with History of Diabetes Mellitus and Infants with Anti-GAD65 Salamy, Nanda Fadhilah Witris; Sari, Gadis Meinar; Purwanto, Bambang; Sulistiawati, Sulistiawati
Folia Medica Indonesiana Vol. 55, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

The aim of this study was to analyze human sperm motility, viability, and morphology before and after cryopreservation. This true laboratory experimental study had pre and post randomized one group design. The study was conducted at the Embryology, Andrology, and Genetics Laboratory, Department of Medical Biology, Faculty of Medicine, Universitas Airlangga from August to November 2017. The eighteen samples of fresh semen were collected from male volunteers who agreed and signed the informed consent of the study. Samples were analyzed their motility, viability, and morphology before and after cryopreservation. Results of this study indicated differentiation between motility before and after cryopreservation. Cryopreservation process decreased progressive motility (42.22 + 9.46%; 17.83 + 6.24%; p< 0.0001) and increased the number of immotile spermatozoa (35.44 + 10.15%; 60.11 + 12.53%; p< 0.0001). Cryopreservation also decreased human sperm viability (73.78 + 8.91%; 40.83 + 12.89%; p< 0.0001) and morphology (10.94 + 4.96%; 7.39 + 3.90%; p< 0.0001). Cryopreservation of human spermatozoa caused the decreased of motility, viability, and morphology.
The Effect of Hypercholesterolemia on Cortical Bone Thickness of Wistar Rats (Rattus norvegicus) Sofka, Auliya Dzaqiyatus; Lestari, Pudji; Sari, Gadis Meinar
Folia Medica Indonesiana Vol. 55, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

There have been several studies reporting the effect of hypercholesterolemia on cortical thickness, but it remains a controversy. Some studies suggest that hypercholesterolemia can decrease osteoblast activity and increase osteoclast activity. Meanwhile other studies suggest that hypercholesterolemia is a protective factor of osteoporosis. Therefore, it is necessary to conduct a study to determine the effect of hypercholesterolemia on cortical bone thickness. Method: This study used 8 rats (Rattus norvegicus) that were divided into 2 groups, including control group (K0) that was given standard diet and experimental group (K1) that was given high fat diet for 28 days and all were executed to obtain the femur bone. The cortical bone thickness was measured by using Optilab Viewer and Optilab Image Raster software. Result: The data analysis was conducted using independent t-test. A p value of <0.05 is considered significant. The results showed that hypercholesterolemia had significant effect on cortical bone thickness. The average cortical bone thickness in the control group was 146.92 µm whereas in the experimental group was 124.53 µm, the mean difference between the two groups was 22.39 µm. There was a 6% decrease of cortical bone thickness. In conclusion, hypercholesterolemia can decrease cortical bone thickness of wistar rats (Rattus norvegicus).
The effect of long term administration of glucocorticoid to bone lining cells apoptosis Sari, Gadis Meinar
Folia Medica Indonesiana Vol. 52, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Glucocorticoid is widely used in medical treatment as an immune system or an inflammation therapy. However its long term administration can cause life-threatening side effects. One of them is bone mass loss which increases the risk of bone fractures in the long-term use. Bone lining cells derived from mesenchymal stem cells, which serve as a backup cell bone-forming osteoblasts. Glucocorticoids acting directly on osteoblasts, bone lining cells when reduced due to increased apoptosis, the reserve cells to bone formation will be decreased. The aim of this study was to count the amount of apoptotic bone lining cells after long term glucocorticoid administration. This study used Rattus norvegicus females aged 3 months that were divided into 3 groups, each group consisted of 7 rats. The groups are: (1) control group; (2) treatment group 1 were given glucocorticoid 0.01 mg/day; (3) treatment group 2 were given glucocorticoid 0.2mg/day. The treatment carried out for 4 weeks and at the end of treatment, rats were sacrified and continued with preparation, and the number of bone lining cells that undergoing apoptosis was calculated through examination of the femur bone tissue metaphysis section using immunohistochemical technique. All data were analyzed with statistical analysis Anova. The result showed that the number of apoptotic bone lining cells increased in group with glucocorticoid administration 0.01 mg/day and 0.2 mg/day compared to control group with p = 0.000 (p <0.05). The number of apoptotic bone lining cells on the group of glucocorticoid dose 0.2 mg/day higher than the group of glucocorticoid dose 0.01 mg/day with p = 0.000 (p <0.05). In conclusion, long term glucocorticoid administration increase apoptosis of bone lining cells.
Effect of Adaptive Exercise on Body Temperature in Children with Motoric Disorder Mulyadi, Soffil Yudha; Rejeki, Purwo Sri; Tinduh, Darmayanti; Sari, Gadis Meinar; Prasetya, Rizka Eka
Folia Medica Indonesiana Vol. 56, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Motoric disorder in child increased every year, especially cerebral palsy. Children with motoric disorder which is majority experiencing long immobilization results in their general condition declining. One of this declining appears on body temperature in child, even lead to hypothermia. A simple exercise which applicatively performed at home can be a simple solution to maintain general condition, especially body temperature. The purpose of this study was to determine effect of adaptive exercise on body temperature change in children with motoric disorder. This study was an experimental study of one group pre and posttest. A total of 31 children (11 girls and 20 boys) aged 2-10 years old performed adaptive exercise consist of warming up 5 minutes, core movement 25 minutes, cooling down 5 minutes. Data were analyzed by paired T test. Body temperature in pretest was 36.12 ± 0.53oC, and body temperature in posttest was 36.63 ± 0.6oC, with p = 0.00. Adaptive exercise can increase body temperature but still in normal range.
Association of Stimulation and Sleep Duration with Developmental Outcomes in Children Aged 12–36 Months: - Purnama Sari, Yulia; Ningtyas, Woro Setia; Puspitasari, Dwiyanti; Meinar Sari, Gadis
Jurnal KESANS : Kesehatan dan Sains Vol 5 No 4 (2026): KESANS: International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v5i4.514

Abstract

Introduction: Early childhood development during the golden years is crucial for future quality of life, yet developmental disorders remain a significant challenge. In Surabaya, Gundih Health Center showed the lowest coverage of developmental monitoring services. Objective: This study aimed to analyze the relationship between stimulation provision and sleep duration with developmental outcomes in children aged 12-36 months at Gundih Health Center, Surabaya. Method: A quantitative analytical study with cross-sectional design was conducted from April to September 2025. Using purposive sampling, 110 children aged 12-36 months were selected. Data were collected through questionnaires adapted from the Maternal and Child Health Book for stimulation assessment, Brief Infant Sleep Questionnaire for sleep duration, and Developmental Pre-Screening Questionnaire for developmental assessment. Data analysis employed univariate and bivariate analysis using Spearman rank correlation test. Result and Discussion: Results showed that 48.2% of children had age-appropriate development, while 51.8% demonstrated questionable development or possible deviations. Statistical analysis revealed a significant relationship between developmental stimulation and child development (p=0.034, r=0.202), indicating that better stimulation correlated with appropriate developmental outcomes. However, no significant relationship was found between sleep duration and child development (p=0.323, r=0.095). Conclusions: Developmental stimulation significantly influences child development outcomes, while sleep duration does not show a direct significant relationship with developmental progress in children aged 12-36
Co-Authors adella wahyuningsih Aditya, Ronal Surya Agustina Yasinta Yami Ahmad Rukhani Lutfi Ahmad Sabili Rifa'i Ainun, Siti Zaimatul Aizah Ari Setyana Yuli Akhmad Jayadi Akmal Zidan Alaudin Alfian Nurfaizi Alfiyah Zahra Ulya Alifia Candra Puriastuti Alifina Izza Alrazeeni, Daifallah M. Amrina Rosyada Amrina Rosyada Ana Silvi Ni'ma Ananta, Silvia Maya Anggreini Wahyu Prastika Annas, Jimmy Yanuar Ariviani, Fauziah Ashon Sa'adi Ashon Sa’adi Atika Atika Bakhtiar, Arief Bambang Purwanto Budipramana, Vicky Sumarki Cakra Waritsu Choesnan Effendi Cornelius Coli Cornelius Coli Damayanti Tinduh David Nugraha Dewi Setyowati Dian Lestari Dwikora Novembri Utomo Dwiyanti Puspitasari, Dwiyanti Dyah Ayu Pradnyaparamitha Eighty Mardiyan K, Eighty Eka Arum Cahyaning Putri Elyana Asnar Endyka Erye Frety Fadhilah Rahmaputri Fatimah, Nurmawati Felisita Maritza Abidanovanty Fitria Amin, Nurhayati Fitriana, Farida Fitriyatul Qulub Galuh Zediara Gatut Hardianto, Gatut Gita Ningrum, Astika Hamidah, Nadhifa Alya Harzat Hening Laswati Putra HERAWATI, LILIK Heri Suroto Hermina Novida, Hermina I Gusti Made Reza Gunadi Ranuh I'tishom, Reny Irdayanti Irdayanti Isnin Anang Marhana Ivon Diah Wittiarika Izza, Alifina Izzati, Dwi Jihadna Prima Santika Ruslan Musanip Kintan Adelia Farahannisa Konginan, Agustina Kurniani Fatma Hardini Lucky Prasetyowati Manggolono, Lintang Nirmalasari Gemalochaya Mei Indarti Melynda Trilamsari Putri Mochammad Yunus, Mochammad Mohammad Fathul Qorib Muhammad Axel Arsyad Nabila Sayyidah Fairuz Zen Nanang Tri Wahyudi Nanda Fadhilah Witris Salamy Nathanael Jordan Nikmatus Sa’adah Ningrum, Astika Gita Nugraha, David Nugroho, Satrio Wahyu Nungki Marlian Yuliadarwati Nurhayati Fitria Amin Paulus Liben, Paulus Pradnyaparamitha, Dyah Ayu Prasetya, Rizka Eka Pratama, Arlingga Prihartini Widiyanti Prihatma Kriswidyatomo Pudji Lestari Purnama Sari, Yulia Putri, Ardelia Savinka Anandrian Rara Yumna Elfrida Rejeki, Purwo Sri Rida Eka Setiani Riri Aprianti RizkaEka Prasetya Septiananda, Farsya Hidayah Setiarini, Debie Shayla Kokomi Rishardy Silvia Maya Ananta Soebagjo, Hendrian Dwikoloso Soffil Yudha Mulyadi Sofka, Auliya Dzaqiyatus Sofka, Auliya Dzaqiyatus Sri Ratna Dwiningsih Sulistiawati Sulistiawati Tinduh, Darmayanti Tiyas Kusumaningrum Tjitra Wardani Triardhana, Yanuar Alfan Wahyul Anis Widjiati Woro Setia Ningtyas Yudi Her Octaviono Yulianti, Erikavitri Zakaria Sendy Wardana