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All Journal HAYATI Journal of Biosciences Damianus Journal of Medicine The Indonesian Biomedical Journal Acta Biochimica Indonesiana Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Ilmiah Biologi UMA (JIBIOMA) Jurnal Kesehatan Tambusai Bioscientist : Jurnal Ilmiah Biologi EduNaturalia: Jurnal Biologi dan Kependidikan Biologi Jurnal Sehat Indonesia (JUSINDO) Tarumanagara Medical Journal Jurnal Sosial dan Sains Ebers Papyrus Jurnal Muara Medika dan Psikologi Klinis Cermin Dunia Kedokteran
Frans Ferdinal
Department Of Biochemistry And Molecular Biology, Faculty Of Medicine, Tarumanagara University, Jakarta, Indonesia
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

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EVALUATION OF ANTIOXIDANT CAPACITY AND TOXICITY OF CHRYSANTHEMUM FLOWER (Chrysanthemum morifolium) EXTRACT Malano, Zahra Khoirunissa; Hendrawan, Siufui; Ferdinal, Frans
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 4 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

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Abstract

The increasing trend of air pollution has worsened the air quality and deteriorated human health. This situation subsequently causes the accumulation of free radicals, leading to oxidative stress, and eventually the emergence of various diseasessuch as. respiratory and degenerative disorders. Indonesia is home to a wide variety of plantsthat may posses medicinal beneficial and efficacy. Chrysanthemum (Chrysanthemum morifolium) is one of the most commonly found flowers and is known to containphytochemicals. Therefore, this research aimed to determine the antioxidant activity and toxicity level of Chrysanthemum morifolium flower extract. In brief, chrysanthemum flowers were dried and extracted, screened for phytochemical content, and tested for antioxidant activity using the Ferric Reducing Antioxidant Power (FRAP) methods. Toxicity assay was determined using the Brine Shrimp Lethality Test. The results showed that the chrysanthemum ectract contained several phytochemicals, including alkaloids, flavonoids, terpenoids, betacyanins, and phenolics.The antioxidant activity test yielded an IC50 value of 11.13 μg/mL, inidicating a very strong antioxidant activity. Meanwhile the toxicity test showed an LC50 value of 15.49 μg/mL. In conclusion, chrysanthemum flowers exhibit very strong antioxidant activity and have potential as an antimitotic agent. Keywords: antioxidant, chrysanthemum flower, phytochemicals, toxicity assay DOI : 10.35990/mk.v8n4.p366-377
Co-Authors . Wardaya Alphanto, Alfred H Alvionica, Selina Ani R. Prijanti Ani Retno Prijanti Annisaa Nurrahma Ardyati Asyraf, Muhammad Zain Alwi Audina Leonita Bethy S. Hernowo Cinthia Catherine Clareta Vero Patricia Widya Darlene Zaneta David Limanan Dewi Sukmawati Dewi, Mietha Apriyanti E Efrany E Yulianti Elhapidi, Nafisa Zulpa Eloydia Vintari, Clarista Enny Yulianti, Enny Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti Eny Yulianti, Eny Erics Efrany Ezra, Pasuarja Jeranding F Wandy Fanny Septiani Farhan Febriana C. Iswanti Felix Felix Ferdian Ferdian Fernando Yosafat Franciscus D. Suyatna Frankson, Desvin Frans D Suyatna Gaofman, Brian Albert Gita Manerlin Kasihita Simatupang H R Helmi Habibah, Rizka Azahra HANS-JOACHIM FREISLEBEN Hartono, Daniswara Aliya Helmi, Helmi Rizal Hilmi, Fakih Jessica Geselda Salim Julianty, Eny Jusman, Sri Widia Azraki Karinnia Karinnia Kusuma, Andrea Bianca Castafiore M Lirendra Maharani, Karennina Larissa Malano, Zahra Khoirunissa Malihah, Ely Marcella, Agnes Maria Christina Dwiyanti Mellenia, Kelnia Michael Chen Mohamad Sadikin Mohamad Sadikin Najukha, Yusrifa Natasha Olivia Christian Ngestinuari Salim Ninik Mudjihartini NO Christian Noer Saelan Tadjudin Novelee Irawan Putri Nurhadi Ibrahim Putri, Nawaika Shafira R Benettan Rizky Audryan Rizky Putri Agustina Rostika Flora Rudianti, Selly Herlia Rumengan, Peterjohn Andrew Benhard Saerang, Stefanus Handy Salim, Melanie Santoso, Stanley Satriotomo, Irawan Sentosa, Belinda Septelia I. Wanandi Setiady, Brandon Alexander Siufui Hendrawan Siufui Hendrawan Sri W.A. Jusman Sri Widia A Jusman Sri Widia A. Jusman Tamba, Monica Diva Maharani Tanowijono, Gabriella Frederica Tanuhariono, Ardhita Felicia Thalia Gabriella Siriwa Wardaya Wardaya Wawan Mulyawan Wawan Mulyawan Wijayadi, Linda Julianti William Lukman