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All Journal Jurnal Kesehatan ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar Jurnal Ilmiah Medicamento Jurnal Midwifery JURNAL PENGABDIAN MASYARAKAT YAMASI Jurnal Farmasi Indonesia Parapemikir Jurnal Ilmiah Farmasi CERATA Jurnal Sains dan Kesehatan
Nurshalati Tahar
Universitas Islam Negeri Alauddin Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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IDENTIFIKASI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN TOBO-TOBO (Ficus septica Burm) TERHADAP BAKTERI ULKUS DIABETIK Munifah Wahyuddin; Afrisusnawati Rauf; Nurshalati Tahar; Nurfitrah Syamsuddin; Huriyah Fadhilah
CERATA Jurnal Ilmu Farmasi Vol 15 No 2 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i2.1103

Abstract

People in Indonesia have long used tobo-tobo leaves (Ficus septica Burm). The ingredients contained in these leaves consist of alkaloid compounds, saponins, flavonoids, and tannins, which are compounds that are antibacterial, so they have the potential to be developed as plants. drug. This study aims to determine the antibacterial activity of the ethanol extract of tobo-tobo leaves against diabetic ulcer bacteria, namely Pseudomonas aeruginosa, Providencia stuartii, Citrobacter freundii, Pseudomonas luteola, Burkholderia cepacia, Acinetobacter baumannii, and Proteus merabilis. For this kind of research, a quantitative experimental method is used. The ethanol solvent is used for extraction, and the agar diffusion method on NA medium is used to test for bacteria. The test showed that the tobo-tobo (Ficus septica Burm) leaf extract made of ethanol had alkaloids, saponins, flavonoids, and tannins in it. In the antibacterial activity test on each extract with a concentration of 20%, 40%, 60%, 80%, and 100%, it was found that the ethanol extract of tobo-tobo leaves at a concentration of 100% gave the greatest antibacterial effect on bacterial growth with an average diameter value of flat. average: Pseudomonas aeruginosa 12.8 mm (strong), Providencia stuartii 9.33 mm (medium), Citrobacter freundii 11.83 mm (strong), Pseudomonas luteola 11 mm (strong), Burkholderia cepacian 10.16 mm (strong), Acinetobacter baumannii 9.5 mm (moderate), and Proteus merabilis 6.5 mm (moderate).
Co-Authors Afrisusnawati Rauf Afrisusnawati Rauf Afrisusnawati Rauf Ahmad Zakir Alifia Putri Febriyanti Alwi, Fitria Andi Arwini Puspitasari Andi Sri Wahyuni Astha Anieq Mumthi’ah Al Kautzar Aswandi Aswandi Auliah Aliah Pertiwi Ayu Tri Sartika Doloking, Haeria Dwi Wahyuni Dwi Wahyuni Leboe Dwi Wahyuni Leboe Egi Dwi Sakti Parenta Faridha Yenny Nonci Faridha Yenny Nonci Faridha Yenny Nonci Fatima Abdurrahman Fitra Insani Gemy Nastity Handayany Haeria Haeria Haeria Haeria Haeria Haeria Haeria Haeria Hamdana Hamdana Huriyah Fadhilah Husniar Husniar Indah Muhtar Irma Erviana Ismail, Asrul Isriany Ismail Khaerani Khaerani Khaerani Khaerani Khaerani Khaerani, Khaerani Leboe, Dwi Wahyuni M.Fais Satrianegara Muh Ikhlas Arsul Muhammad Fitrah Muhammad Rusdi Mukhriani Mukhriani, Mukhriani Mulyanti Mulyanti Munadiah Munadiah Mutia Fitri Almaidah Nimas Mulan Cahyani Nonci, Faridha Yenny Nur Annisa Maulidia David Nur Azizah Syahrana Nur Hikmah Ramadhani Nur Syamsi Dhuha Nurfajri Indriani Nurfitrah Syamsuddin Nursalam Hamzah Nursyamsi Dhuha Qoriatul Aini Rabiatul Adawiyah Resnia Resnia Roni, Abdul Rukmana, Sitti Rusmadi Rukmana Rusmadi Rusmadi Surya Ningsi Surya Ningsi Surya Ningsi Syahifah Auliyah Hasti Wahyuddin, Munifah Yuliani Yuliani Yuri Erika Arifin