Article Per Year (5 Year)
p-Index From 2020 - 2025
1.503
P-Index
This Author published in this journals
All Journal Jurnal Sain Veteriner Jurnal Veteriner Jurnal Peternakan Indonesia Jurnal Ilmiah Mahasiswa Veteriner Jurnal Kedokteran Hewan Jurnal Medika Veterinaria Jurnal Agripet
Rosmaidar Rosmaidar
Fakultas Kedokteran HEwan Universitas Syiah Kuala, Banda Aceh
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

Published : 18 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 18 Documents
Search

 1   2 
Perbandingan Kinerja Berahi dan Level Estradiol Kambing Kacang dan Kambing Nubian yang Diinduksi dengan PGF2α Mulyadi Adam; Raja Nurul Huda; Widya Zahara; Tongku Niswan Siregar; Sri Wahyuni; Cut Nila Thasmi; Rosmaidar Rosmaidar
Jurnal Sain Veteriner Vol 36, No 1 (2018): Juni
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (10432.789 KB) | DOI: 10.22146/jsv.38444

Abstract

The experiment was conducted to compare estrous performance between and estradiol level kacang and Nubian goats estrous induction by prostaglandin F2 alpha (PGF2α). Eight female goats were divided into two groups, groups 1 (K1) consisted five Nubian goats and group 2 (K2) included three kacang goats with criterias as follows: age 1.5-3.0 years old, not pregnant, at least two months postpartum, and healthy clinically. All goats were estrous synchronized by double injection 7,5 mg PGF2α intramuscularly with 10 days interval. Goats that appeared estrus symptoms were mated naturally to a male goat. Determination of estrous intensity was performed using scoring method. Blood samples were taken at the first time the goats were mated (day 0). The measurement of estradiol concentration was done by enzyme linked immunosorbent assay (ELISA) method. Data of intensity, onset, duration, and estradiol level were analyzed using t test. The results showed that the rate of intensity, onset, duration, and estradiol level of estrous at KI vs KII were 2.08±0.52 vs 1.85±0.67, 56.00±34.11 vs 40.80±18.20 hours, and 24.00±26.15 vs 33.80±9.10 hours, and 103.51±42.49 vs 67.95±38.44 pg/ml (P>0,05). It can be concluded there was no difference of estrous performance and estradiol level between kacang and Nubian which estrous induction with PGF2α. The relationship between the intensity of estrus estradiol level in the Nubian goats was 0.995 while the kacang goats was 0.890.
Pemberian Ekstrak Akar Pasak Bumi Meningkatkan Kualitas Spermatozoa Domba Waringin Amalia Sutriana; Mira Ayu Lestari Hasibuan; Nurhazimah Nurhazimah; Teuku Armansyah; Tongku Nizwan Siregar; Budianto Panjaitan; Hafizuddin Hafizuddin; Arman Sayuti; Dwinna Aliza; Rosmaidar Rosmaidar
Jurnal Veteriner Vol 22 No 3 (2021)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.503 KB) | DOI: 10.19087/jveteriner.2021.3.317

Abstract

Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak akar pasak bumi (Eurycoma longifolia Jack) terhadap peningkatan konsentrasi testosteron domba Waringin. Dalam penelitian ini digunakan dua ekor domba waringin jantan berumur ±4 tahun. Penelitian ini merupakan penelitian eksperimen dengan menggunakan rancangan pola bujur sangkar latn 2 x 2 sehingga hewan percobaan diberi perlakuan 20 mL akuades per oral sebagai kontrol (P1) dan 20 mL larutan yang mengandung 45 mg/kg bobot badan ekstrak pasak bumi yang diberikan per oral (P2). Perlakuan diberikan selama enam hari pada pukul 09.00 WIB. Pada bulan ke-1 domba pertama mendapat perlakuan P1 sedangkan domba kedua mendapat perlakuan P2. Sebaliknya, pada bulan ke-2 domba pertama mendapat perlakuan P2 sedangkan domba kedua mendapat perlakuan P1. Koleksi darah untuk pemeriksaan konsentrasi hormon testosteron dilakukan lima jam setelah pemberian ekstrak akar pasak bumi (Eurycoma longifolia Jack). Analisis konsentrasi testosteron dilakukan menggunakan metode enzyme linked immunosorbent assay (ELISA) yang diukur pada hari 1, 3 dan 6. Data yang diperoleh dianalisis dengan uji sidik ragam pola bujur sangkar latin. Hasil analisis statistika menunjukkan bahwa volume semen, motilitas spermatozoa, viabilitas spermatozoa dan abnormalitas spermatozoa pada domba yang diberikan ekstrak akar pasak bumi (E. longifolia Jack) menunjukkan perbedaan yang signifikan (P<0,05) dibandingkan dengan kontrol namun konsentrasi testosteron tidak menunjukkan perbedaan yang signifikan (P>0,05). Disimpulkan bahwa pemberian ekstrak akar pasak bumi meningkatkan kualitas spermatozoa namun tidak menyebabkan peningkatan konsentrasi hormon testosteron pada domba waringin.
PENGARUH PAPARAN TIMBAL (Pb) TERHADAP HISTOPATOLOGIS USUS IKAN NILA (Oreochromis nilloticus) The Effect of Lead (Pb) Exposure to the Histopathology of Nile Tilapia (Oreochromis nilloticus) Intestine Rosmaidar Rosmaidar; Nazaruddin Nazaruddin
JURNAL ILMIAH MAHASISWA VETERINER Vol 2, No 1 (2017): NOVEMBER - JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.178 KB) | DOI: 10.21157/jim vet..v2i1.5659

Abstract

Penelitian ini bertujuan mengetahui pengaruh paparan timbal (Pb) terhadap histopatologis usus ikan nila (Oreochromis nilloticus). Penelitian ini menggunakan ikan nila sebanyak 12 ekor dengan kriteria: sehat, bobot badan     15- 18 gram, umur ± 2 bulan, dan jenis kelamin jantan. Penelitian ini merupakan penelitian eksperimental laboratorik dengan desain rancangan acak lengkap yang terdiri dari 4 kelompok perlakuan masing-masing dengan 3 ulangan. Semua kelompok diberikan pakan berupa pelet. Kelompok P0 sebagai kontrol, ikan hanya diberi pakan pelet, P1 diberikan paparan timbal 6,26 mg/L, P2 diberikan paparan timbal 12,53 mg/L, dan P3 diberikan paparan timbal 25,06 mg/L. Perlakuan dilakukan selama 30 hari, dan pengambilan organ usus dilakukan pada hari 31. Sampel usus kemudian diambil dan difiksasi dalam larutan fiksasi dilanjutkan dengan pembuatan sediaan histopatologis dan pewarnaan haematoksilin dan eosin (HE). Pengamatan histopatologis dilakukan dengan mikroskop cahaya biokuler, kemudian untuk pengambilan gambar dengan menggunakan fotomikrograf. Data yang diperoleh dianalisis secara deskriptif.  Hasil pemeriksaan histopatologis usus ditemukan edema, degenerasi lemak, nekrosis, erosi vili usus dan lisis vili usus. Dari hasil ini menunjukkan bahwa semakin tinggi konsentrasi timbal yang diberikan semakin parah kerusakan organ usus yang terjadi. Berdasarkan hasil penelitian dapat disimpulkan bahwa kosentrasi timbal 6,26 mg/l, 12,53 mg/l dan 25,06 mg/l dapat menyebabkan kerusakan jaringan secara histopatologis.The aims of this research was to find out to determine the effect of lead (Pb) exposure to the histopathology of Nile tilapia (Oreochromis nilloticus) intestinal. This study used 12 tilapia fish with criteria: healthy, body weight 15-18 gram, age ± 2 month, and male sex. This study, is a laboratory experiment using complete randomized design with 4 treatments groups, each group were repeated 3 times. Each groups were fed with pellet. P0 as control, fish fed only pellets, P1 is given lead exposure 6,26 mg/L and pellet feed, P2 is given lead exposure 12,53 mg/L and pellet feed and P1 is given lead exposure 25,06 mg/L. Treatment carried out for 30 days, and fish were  euthanized on 31 days. Intestinal samples were collected and fixed in fixation solution followed by histopathology preparation using haematoxylin and eosin (HE) staining. Histopathologic observations were performed with a biocular light microscope, then for shooting using photomicrograph. The data obtained were analyzed descriptively. Edema, fat degeneration, necrosis, erotion of intestine villi and lisis of intestine villi were found as the result of intestine histopathologic test. This result showed that higher lead concentration causes more severe intestine damage that occur. From this result can be concluded that 6,26 mg/l, 12,53mg/l and 25,06 mg/l causes tissue damage histopathologically.
PENGARUH PAPARAN TIMBAL (Pb) TERHADAP HISTOPATOLOGIS INSANG IKAN NILA (Oreochromis nilloticus). The Effect of Lead (Pb) Exposure to the Histopathology of Nile Tilapia (Oreochromis nilloticus) Gill Rosmaidar Rosmaidar; Nazaruddin Nazaruddin; T Armansyah TR; Ummu Balqis; Yudha Fahrimal
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 4 (2017): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.999 KB) | DOI: 10.21157/jim vet..v1i4.5091

Abstract

Penelitian ini bertujuan mengetahui pengaruh paparan timbal (Pb) terhadap histopatologis insang  ikan nila (Oreochromis nilloticus). Penelitian ini menggunakan ikan nila sebanyak 12 ekor dengan kriteria: sehat, bobot badan 15-18 gram, umur ± 2 bulan, jenis kelamin jantan. Penelitian ini merupakan penelitian eksperimental laboratorik dengan desain rancangan acak lengkap yang terdiri atas 4 kelompok perlakuan masing-masing dengan 3 ulangan. Semua kelompok diberikan pakan pelet. Kelompok P0 sebagai kontrol, ikan hanya diberi pakan pelet, P1 diberikan paparan timbal  6,26 mg/l, P2 diberikan paparan timbal 12,53 mg/l, dan P3 diberikan paparan timbal 25,06 mg/l. Perlakuan dilakukan selama 30 hari, dan pengambilan organ insang dilakukan pada hari 31. Sampel insang kemudian diambil dan difiksasi dalam larutan Davidson 10% dilanjutkan dengan pembuatan sediaan histopatologis dan pewarnaan hematoksilin dan eosin (HE). Pengamatan histopatologis dilakukan dengan mikroskop cahaya biokuler, kemudian untuk pengambilan gambar dengan menggunakan fotomikrograf. Data yang diperoleh dianalisis secara deskriptif.  Hasil pemeriksaan histopatologis insang ditemukan edema, kongesti, nekrosis, hiperplasia lamela sekunder, dan fusi lamela. Dari hasil ini menunjukkan bahwa semakin tinggi kosentrasi timbal yang diberikan semakin parah kerusakan organ insang yang terjadi. Berdasarkan hasil penelitian dapat disimpulkan bahwa kosentrasi timbal dapat meningkatkan kerusakan jaringan secara histopatologis.The aims of this research was to determine The effect of lead (Pb) exposure to the histopathology of Nile tilapia (Oreochromis nilloticus) gill. This study used 40 tilapia fish with criteria: healthy; body weight 15-18 gram; age ± 2 month; male sex. This study, is a laboratory experiment (in vivo) using complete randomized design with 4 treatments groups, each group were repeated 3 times. Each groups were fed with pellet. P0 as control, fish fed only pellets, P1 is given lead exposure 6,26 mg/L and pellet feed, P2 is given lead exposure 12,53 mg/L, P3 is given lead exposure 25,06 mg/L. Treatment carried out for 30 days, and fish were  euthanized on  the 31st days. Gill samples were then collected and fixed in Davidson 10% solution followed by histopathology preparation using haematoxylin and eosin (HE) staining. Histopathologic observations were performed using a biocular light microscope, then for using photomicrograph. The data obtained were analyzed descriptively. The results of gill histopathologic examination found edema, congestion, necrosis, primary and secondary lamellae hyperplasia, and lamellae fusion. The result showed that the higher lead concentration the more severe damage on fish gills.  Based on result of this research can be conclided that lead concertration can increased tissue demage histopathologically.
PENGARUH PAPARAN TIMBAL (Pb) TERHADAP HISTOPATOLOGIS HATI IKAN NILA (Oreochromis nilloticus) ( The effect of lead (Pb) exposure to the histopathology of Nile tilapia (Oreochromis nilloticus) liver) Rosmaidar Rosmaidar; Nazaruddin Nazaruddin; winaruddin winaruddin; Ummu Balqis; T. Armansyah TR
JURNAL ILMIAH MAHASISWA VETERINER Vol 1, No 4 (2017): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.944 KB) | DOI: 10.21157/jim vet..v1i4.4992

Abstract

ABSTRAK Penelitian ini bertujuan mengetahui pengaruh paparan timbal  terhadap histopatologis hati ikan nila (Oreochromis nilloticus).Penelitian ini menggunakan ikan nila sebanyak 12 ekor dengan kriteria: sehat; bobot badan 10 – 20 gram; umur ± 2 bulan; jenis kelamin jantan.Rancangan yang digunakan adalah Rancangan Acak Lengkap (RAL) pola searah dengan 4 kelompok perlakuan dan 3 ulangan. Semua kelompok diberikan pakan pelet yang diberikan setiap hari. Kelompok P0 sebagai kontrol, ikan hanya diberi pakan pelet, P1 diberikan paparan timbal 6,26 mg/l, P2 diberikan paparan timbal 12,53 mg/l dan P3 diberikan paparan timbal 25,06 mg/l.Perlakuan dilakukan selama 30 hari dan ikan dietanasi pada hari ke-31. Hasil menunjukan rata-rata (± SD) jumlah sel-sel hepatosit hati pada ikan  yang mengalami degenerasi P0 (0,93 ± 0,61); P1 (18,73 ± 4,95); P2 (22,33 ± 4,57);dan P3 (44,80 ± 5,20); dan nekrosis P0 (0,73 ± 0,50); P1 (8,53 ± 2,50); P2 (8,93 ± 0,83); dan P3 (16,73 ± 2,00). Dari hasil penelitian dapat disimpulkan bahwa paparan timbal dengan dosis 25,06 mg/l menyebabkan kerusakan degenerasi dan nekrosis yang berat secara histopatologis pada sel hepatosit hati ikan nila (Oreochromis nilloticus).ABSTRACT The aims of this research was to find out to determine the level of lead (Pb) concentration that affect the rate of growth tilapia fish (Oreochromis nilloticus). This study used twelve tilapia fish with criteria: healthy; body weight 10-20 gram; age ± 2 month; male sex. The research was designedby a completely randomized design (CRD) with 4 unidirectional patterngroup treatments and three reins. All groups are given pellet feed given daily. GroupP0 as control, fish fed only pellets, P1 is given lead exposure 6,26 mg/l, P2 is given lead exposure 12,53 mg/l and P3 is given lead exposure 25,06 mg/l. Treatment carried out for 30 days andfish were euthanized on day 31. The statistical analysis showed that the average (± SD) number of hepatocyte liver cells in fish with degeneration wereP0 (0.93 ± 0.61), P1 (18.73 ± 4.95), P2 (22.33 ± 4.57), and P3 (44.80 ± 5.20), and necrosis were P0 (0.73 ± 0.50), P1 (8.53 ± 2.50), P2 (8.93 ± 0.83), and P3 (16.73 ± 2.00). From the results of the study can be concluded lead exposure with dose 25,06 mg/l cause damage degeneration and necrosis which is heavily histopatological in hepatocytes cell of Nile tilapia (Oreochromis nilloticus) liver.
Pengaruh Dosis Sperma Yang Diinseminasikan Terhadap Fertilitas Dan Daya Tetas Telur Ayam Kampung (Gallus Domestica) Wira Asyudi; Dasrul Dasrul; Juli Melia; Ginta Riady; Rosmaidar Rosmaidar; Ismail Ismail
JURNAL ILMIAH MAHASISWA VETERINER Vol 6, No 4 (2022): AGUSTUS-OKTOBER
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v6i4.21408

Abstract

ABSTRAKSPeningkatan populasi ayam kampung salah satunya dapat dilakukan dengan penerapan metode inseminasi buatan (IB).Tujuan penelitian ini yaitu , untuk dapat mengetahui bagaimana pengaruh tingkat dosis dari spermatozoa yang diinsiminasikan terhadap tingkat fertilitas dan daya tetas telur ayam kampung. Tujuan dari Dosis IB ini, agar dapat mengetahui tingkat perbandingan ayam jantan dan ayam betina yang paling efisien dalam suatu pemeliharaan. Pada ayam jantan,dilakukan penampungan pada semennya, kemudian semen tersebut, dicampur dari 3 ekor ayam kampung jantan yang berumur sekitar 12-15 bulan. Konsentrasi spermatozoa semen yang telah diketahui, dibagi menjadi 3 bagian, lalu semen tersebut,kemudian dilakukan pengenceran masing masing semen dengan NaCl fisiologis hingga akhirnya diperoleh dosis akhir sebagai berikut, 50x106 /0,1 ml adalah perlakuan dosis 1, perlakuan 100x106 /0,1 ml adalah perlakuan dosis 2 , 200x106 /0,1 ml adalah perlakuan dosis 3. kemudian, terhadap 15 ekor ayam kampung betina, dilakukan inseminasi, agar dapat mengetahui bagaimana pengaruh dosis terhadap fertilitas dan daya tetas telur. Ayam betina yang digunakan untuk IB adalah ayam betina umur sekitar 12 – 18 bulan. Hasil penelitian menunjukkan bahwa perlakuan dosis spermatozoa berpengaruh pada fertilitas dan daya tetas telur ayam kampung. Masing-masing perlakuan dosis 1, 2, dan 3, fertilitas telurnya adalah 52,00 ± 10,95%; 72,00 ± 17,89 %; dan 80,00 ± 14,14 %,sedangkan daya tetas terluar, persentasenya adalah 44,00 ± 16,73 %; 60,00 ± 14,14 %; dan 72,00 ± 10,95%. Kesimpulan dari penelitian ini adalah dosis sperma berpengaruh pada fertilitas dan daya tetas telur ayam kampung.ABSTRACTOne the way to increase the population of native chickens is by applying the artificial insemination (IB) method.The purpose of this study was to determine the effect of the dose level of the infected spermatozoa on the level of fertility and hatchability of free – range chicken eggs. The purpose of this IB dose, in order to determine the level of comparison of the most efficient rooster and hen in a maintenance. For rooster, the semen is collected, then the cement is mixed from 3 male free – range chickens aged about 12 – 15 months. The known concentration of sperm spermatozoa is divided into 3 parts, then the semen is then diluted with physiological NaCl until the final dose is obtained as follows, 50 x 106/0,1 ml is treatment dose of 1, 100 x 106/0,1 ml is the treatment dose 2, 200 x 106/0,1 ml is the treatment dose 3. Then, 15 female free – range chickens were inseminated, in order to find out how the dose affects fertility and hatchability. The hens used for IB are hens aged 12 – 18 months. The results showed that the spermatozoa dose treatment had an effect on the fertility and hatchability of native chicken eggs. For each treatment dose 1, 2, dan 3, the egg fertility was 52 ± 10.95%; 72.00 ± 17.89%;and 80.00 ± 14.14%, while the outermost hatchability, the percentage was 44,00 ± 16.73%; 60.00 ± 14.14%; and 72.00 ± 10.95%. The conclusion of this study is that the dose of sperm has an effect on fertility and hatchability of native chicken eggs. 
Skrining Senyawa Aktif Biji Pinang (Areca Catechu, L) Dalam Meningkatkan Sensitivitas Antikanker Doxorubicin Pada Kanker Payudara Secara In Silico Frengki Frengki; Andika Trihadi Septian; Daniel Daniel; Rosmaidar Rosmaidar; Hennivanda Hennivanda; T. Armansyah TR; Nazaruddin Nazaruddin; M. Hasan
JURNAL ILMIAH MAHASISWA VETERINER Vol 7, No 1 (2022): NOVEMBER-JANUARI
Publisher : JURNAL ILMIAH MAHASISWA VETERINER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/jim vet..v7i1.23723

Abstract

ABSTRAK Doxorubicin merupakan kemoterapi golongan antrasiklin yang cukup ampuh dan masih digunakan dalam mengatasi kanker payudara. Selain efek kemoterapi yang diharapkan, penggunaan doxorubicin juga menimbulkan efek samping hingga memicu peristiwa autoresistensi doxorubicin melalui peningkatan ekspresi dan fungsi NFκβ. Salah satu upaya meningkatkan sensitivitas doxorubicin yaitu dengan menggunakan agen kemopreventif non-toksik sebagai bagian dari kombinasi agen kemoterapi. Tujuan penelitian ini adalah untuk membuktikan senyawa aktif yang terkandung dalam biji pinang (Areca catechu, L) yang berpotensi meningkatkan sensitivitas doxorubicin melalui inhibisi reseptor NFκβ. Penelitian ini dilakukan secara in silico melalui metode Moleculer Docking menggunakan software MOE. Bahan uji berupa data “canonical SMILES” 6 senyawa aktif biji pinang, senyawa deoxyelephantopin dan doxorubicin diunduh dari www.pubchem.org, sedangkan reseptor NFκβ (PDB id. 1VKX) diunduh dari www.rcsb.org.  Hasil docking menunjukkan bahwa senyawa aktif pilihan (protoanthocyanidin, arecaidine, arecoline, guvacoline, guvacine, dan isoguvacine) yang terkandung dalam biji pinang mampu meningkatkan sensitivitas antikanker doxorubicin melalui penekanan fungsi NFκβ dengan proanthocyanidin memiliki kemampuan inhibisi terbaik. Dengan demikian semua senyawa tersebut memiliki kemampuan meningkatkan sensitivitas antikanker doxorubicin sehingga dapat bekerja lebih optimal dalam mengatasi sel kanker payudara. Profil profil farmakokinetika dan toksisitas menunjukkan potensi proanthocyanidin sebagai kandidat obat antidiabetes hanya dapat diberikan secara parenteral.Kata Kunci : Doxorubicin, proanthocyanidin, moleculer docking.ABSTRACTDoxorubicin is an anthracycline class of chemotherapy that is quite effective and is still used in treating breast cancer. In addition to the expected chemotherapy effects, the use of doxorubicin also causes side effects that trigger doxorubicin autoresistance through increased expression and function of NFκβ. One effort to increase the sensitivity of doxorubicin is by using non-toxic chemopreventive agents as part of a combination of chemotherapeutic agents. The purpose of this study was to prove that the active compounds contained in areca nut (Areca catechu, L) seeds have the potential to increase doxorubicin sensitivity through inhibition of NFκβ receptors. This research was conducted in silico through the Molecular Docking method using MOE software. The test material in the form of "canonical SMILES" data for 6 active compounds in areca seed, deoxyelephantopin and doxorubicin compounds was downloaded from www.pubchem.org, while the NFκβ receptor (PDB id. 1VKX) was downloaded from www.rcsb.org. The docking results showed that selected active compounds (protoanthocyanidin, arecaidine, arecoline, guvacoline, guvacine, and isoguvacine) contained in areca nut seeds were able to increase the anticancer sensitivity of doxorubicin by suppressing NFκβ function with proanthocyanidin having the best inhibitory ability. Thus all these compounds have the ability to increase the anticancer sensitivity of doxorubicin so that they can work more optimally in treating breast cancer cells. The pharmacokinetic and toxicity profiles show the potential of proanthocyanidin as an antidiabetic drug candidate which can only be given parenterally.Keywords : Doxorubicin, proanthocyanidin, moleculer docking.
Isolasi dan Identifikasi Bakteri Gram Positif Staphylococcus aureus dan Micrococcus pada Peternakan Sapi yang Terindikasi Mastitis Siti Rani Ayuti; Widya Nur Hidayati; Masda Admi; Rosmaidar Rosmaidar; Zainuddin Zainuddin; Hennivanda Hennivanda; Ali Makmur
Jurnal Peternakan Indonesia (Indonesian Journal of Animal Science) Vol 25, No 1 (2023): Jurnal Peternakan Indonesia
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jpi.25.1.98-109.2023

Abstract

Mastitis menjadi salah satu penyakit yang menyebabkan penurunan produksi ternak dan sulit disembuhkan dengan menggunakan antibiotik dan dapat menimbulkan residu, serta memicu resistensi antibiotik. Penelitian ini bertujuan untuk mengetahui bakteri Gram positif yang dapat menjadi penyebab mastitis pada sapi. Penelitian menggunakan sampel yang diambil dari peternakan rakyat dengan cara swab ambing ternak. Isolasi bakteri dilakukan dengan cara penanaman pada media Mannitol Salt Agar (MSA) dan melakukan Identifikasi dengan pewarnaan Gram, Uji Katalase dan Uji biokimia (maltosa dan laktosa). Data dianalisis menggunakan analisis deskriptif yaitu jenis-jenis bakteri sebagai agen penyebab mastitis. Hasil penelitian yang didapatkan sebagai bakteri penyebab mastitis spesies Staphylococcus aureus dan Micrococcus sp. yang tergolong pada bakteri Gram positif. Dapat disimpulkan bahwa pada sapi terindikasi mastitis terdapat bakteri Gram positif, hal tersebut secara morfologi diidentifikasi yaitu Staphylococcus aureus dan Micrococcus.
CORRELATION BETWEEN PROGESTERONE HORMONE CONCENTRATION AND NUMBER OF FETUSES OF ETAWA CROSSBRED GOAT IN DIFFERENT GESTATION PERIOD Syafruddin Syafruddin; Khairul Rizal; Rosmaidar Rosmaidar; Juli Melia; roslizawaty roslizawaty; Zuhrawati Zuhrawati; Erdiansyah Rahmi; Mahdi Abrar
Jurnal Kedokteran Hewan Vol 11, No 3 (2017): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.248 KB) | DOI: 10.21157/j.ked.hewan.v11i3.8687

Abstract

This study aimed to investigate the correlation between progesterone hormone concentration and number of fetus as well as the difference in progesterone hormone concentration from different gestation periods in Etawah crossbred (EC). Five EC goats used in this study were injected with 2 mL of 5.5 mg prostaglandin F2α (PGF2α, Capriglandin) intramuscularly, with an interval of 10 days. Goats that showed symptoms of estrus were mated naturally with male goats. Blood samples were taken on the 7th, 14th, 21st, and 75th days of gestation. Progesterone hormone concentration was determined using enzyme linked immunosorbent assay (ELISA). The number of fetus was determined at 35th gestational day using ultrasonography (USG). Four out of 5 goats were found to have 1 fetus and 1 goat had 2 fetuses. The progesterone concentration on the 7th, 14th, 21st, and 75th days of gestation in goats with single fetus were 5.21, 7.78, 11.97, and 18.78 ng/mL, respectively, while in goat with two fetuses were 8.44, 14.53, 16.81, and 22.73 ng/mL, respectively. The correlation (r) between progesterone hormone concentration and number of fetus on the 7th, 14th, 21st, and 75th days of gestation were 0.442, 0.854, 0.592, and 0.757, respectively. It is concluded that progesterone concentrations are highly correlated to the number of fetus in each gestation period in EC goats.
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN MALAKA (Phyllantus emblica) TERHADAP MENCIT (Mus musculus). (Acute Toxicity Test of Ethanolic Extract of Malaka (Phyllantus emblica) Leaves on Mice (Mus musculus)) T. Armansyah TR; Sudi Indriany; Amalia Sutriana; Rosmaidar Rosmaidar; Nuzul Asmilia; Budianto Panjaitan; Dwinna Aliza; Hamdan Hamdan
Jurnal Kedokteran Hewan Vol 10, No 2 (2016): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (85.831 KB) | DOI: 10.21157/j.ked.hewan.v10i2.5137

Abstract

ABSTRACT The aim of this research was to asses the acute toxicity of ethanolic extract of malaka leaves using lethal dose 50 (LD50) on mice (Mus musculus). Twenty male mice weighing between 20-30 g were randomly divided into 4 groups (group K1-K4) of 5 mice each. All mice in group K1, K2, K3, and K4 were administered ethanolic extract of malaka leaves with the dose of 2, 4, 8, and 16 g/kg bw, respectively. Single dose of ethanolic extract of malaka leaves were given by oral gavage prior to clinical observation . The observation period was 14 days post administration, for sign of toxicity symptom, weight loss, and mortality. The result showed that no mortality was observed in the experimental animals during this study. Slight reduction of body weight was observed in group K2, K3, and K4, and no toxicity sign was found during fourteen days of observation. The LD50 of ethanolic extract of malaka leaves was higher than 16 g/kg body weight, thus, the substance was practically non toxic substance.
Co-Authors Ali Makmur Amalia Sutriana Andika Trihadi Septian Annisa Anwar Sitorus Arman Sayuti Budianto Panjaitan Budianto Panjaitan Cut Nila Thasmi Daniel Daniel Dasrul Dasrul Dian Masyitha Dwinna Aliza Erdiansyah Rahmi Frengki Frengki Ginta Riady Hafizuddin Hafizuddin Hafizuddin Hafizuddin Hamdan Hamdan Hasan Al Aslam Hattanul Mulia Hennivanda Hennivanda Hennivanda Hennivanda Herrialfian . Indi Rafika Ismail Ismail Jesica Ramadhanita Juli Melia Khairul Rizal M. Hasan Mada Admi Mahdi Abrar Masda Admi Mimi Herlina Mira Ayu Lestari Hasibuan Mulyadi Adam Nazaruddin Nazaruddin Nazaruddin Nazaruddin Nurhazimah Nurhazimah Nuzul Asmilia Raja Nurul Huda Rinidar Rinidar roslizawaty roslizawaty Siti Rani Ayuti Sri Wahyuni Sudi Indriany Sugito Sugito Syafruddin Syafruddin T Armansyah TR T. Armansyah T. Armansyah TR T. Armansyah TR Teuku Armansyah Tongku Niswan Siregar Tongku Nizwan Siregar Ummu Balqis Widya Nur Hidayati Widya Zahara winaruddin winaruddin Winaruddin Winaruddin Wira Asyudi Yudha Fahrimal Zainuddin Zainuddin Zuhrawati Zuhrawati