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All Journal Jurnal Ilmiah Farmasi Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Andalas Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmiah Universitas Batanghari Jambi Martabe : Jurnal Pengabdian Kepada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Jurnal Ilmu Kefarmasian Indonesia JURNAL MEDIA KESEHATAN Jurnal Farmagazine Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical And Biomedical Sciences Journal (PBSJ) Journal of Pharmaceutical and Sciences.
Henny Lucida
Fakultas Farmasi, Universitas Andalas
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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OPTIMASI KOMBINASI PENGHANCUR DAN PENGIKAT DALAM FORMULASI TABLET EKSTRAK ETANOL DAUN Eugenia cumini Merr. Lucida, Henny; Saputra, Harry; Arifin, Helmi
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 4, No 3 (2009)
Publisher : Indonesian Research Gateway

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Abstract

Preclinical studies of the aethanolic extract of the leaves of Eugenia cumini Merr (Jamblang, jambu kaliang) showed that it decreased the blood glucose level of mice at the doses of 50, 100 dan 200 mg/kg BW respectively. The extract was not toxic with the LD50 >15g/kg BB. The acute and sub-acute toxicity studies indicated that the extract was safe for a long use in mice. These results supported the potencial of this extract to be formulated as drug. This study reported the optimization technique used in the formulation of tablet of the aethanolic extract of Eugenia cumini Merr leaves to obtain best formulation with combination of dissintegrant and binder with respect to tablet dissintegration time. Four formulations containing  250 mg of extract were prepared by wet granulation. Results showed that granules of each formulas fulfilled the requirements of granules physical properties except granules a and b for its moisture content. The tablets also fulfilled the Indonesia Phamacopeia requirements except formula b for dissintegration time. Formulation of tablet based on optimization (amprotab 11% and PVP 2%) resulted in tablets with dissintegration time of 499 seconds (contour plot showed 443 seconds). ABSTRAK Uji preklinis menunjukkan bahwa ekstrak etanol daun Eugenia cumini Merr (Jamblang, jambu kaliang) dengan dosis 50, 100 dan 200 mg/kg BB dapat menurunkan kadar glukosa darah hewan percobaan. Ekstrak ini tergolong tidak toksik dengan LD50 >15g/kg BB. Uji toksisitas akut  dan toksisitas sub akut menunjukkan bahwa ekstraks ini aman digunakan dalam jangka waktu lama. Dengan demikian senyawa ini berpotensi untuk dikembangkan menjadi fitofarmaka. Makalah ini melaporkan hasil penelitian tentang optimasi kombinasi penghancur dan pengikat dalam formulasi tablet antidiabetes dari ekstrak etanol daun Eugenia cumini Merr. Dibuat empat formula tablet yang mengandung ekstrak sebesar 250 mg secara granulasi basah, dengan amprotab sebagai penghancur dan polivinilpirolidon (PVP) sebagai pengikat. Respon yang diukur adalah sifat fisik granul, sifat fisik tablet dan waktu hancur tablet. Hasil penelitian menunjukkan bahwa granul yang dihasilkan memenuhi persyaratan uji sifat fisik granul kecuali formula a dan b untuk uji kandungan lembab. Tablet yang dihasilkan memenuhi persyaratan tablet menurut Farmakope Indonesia kecuali formula b untuk waktu hancur tablet. Variasi konsentrasi amprotab berpengaruh dominan terhadap waktu hancur tablet dibandingkan dengan variasi konsentrasi PVP. Formulasi tablet ekstrak etanol daun Eugenia cumini Merr berdasarkan hasil optimasi (amprotab 11% dan polivinilpirolidon 2%) memberikan tablet dengan waktu hancur 499 detik.
FORMULATION OF ANTI-PLAQUE TOOTHPASTE FROM STANDARDIZED GAMBIR EXTRACT AND ITS ANTIMICROBIAL ACTIVITY Lucida, Henny; Rustini, .; Saufitri, Dian; Dachriyanus, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 5, No 2 (2010)
Publisher : Indonesian Research Gateway

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Abstract

Telah dilakukan formulasi pasta gigi ekstrak gambir terstandarisasi serta uji daya antimikrobanya terhadap pertumbuhan bakteri penyebab plak Streptococcus mutans. Uji pendahuluan menunjukkan bahwa ekstrak gambir terstandarisasi pada kadar 7% memiliki diameter hambat optimal terhadap pertumbuhan mikroba uji. Berdasarkan ini dibuat 3 formula pasta gigi dengan kadar ekstrak gambir terstandarisasi sebesar 7% dengan kosentrasi kalsium karbonat (abrasif) yang bervariasi, berturut-turut 37, 42 dan 47%. Semua formula diuji sifat-sifat farmasetik dan aktivitas antimikrobanya, sebagai pembanding digunakan pasta gigi “F”. Hasil evaluasi sifat farmasetika sediaan menunjukkan semua formula memenuhi persyaratan pastagigi yang baik.  Formula 3 (F3) memberikan diameter hambat paling baik (19,25 + 0,50 mm), sedangkan pembanding “F” memberikan diameter hambat (20,0 + 0,00 mm).  Terdapat perbedaan bermakna diameter hambat antar perlakuan (basis versus pasta gigi ekstrak gambir) pada taraf kepercayaan  0,05.   ABSTRACT A toothpaste containing standardized gambir extract had been formulated and an antimicrobial assay of the toothpaste against Streptococcus mutans had been done. Preliminary study showed that the concentration of gambir extract of 7 % obtained an optimal range of inhibition of S. mutans growth. Three formulas were then prepared, which contained 7 % extract and various concentrations of calcium carbonate (37, 42 and 47 % respectively). The formulas were subjected to evaluation procedures including the pharmaceutical properties and the antimicrobial activity in comparison to commercial formula “F”. Results indicated that all formulas had good pharmaceutical properties. F3 showed the best inhibition against the growth of S mutans (diameter of inhibition =  19,25 + 0,50 mm) while that of the commercial toothpaste “F” was (20,0 + 0,00 mm) , which was significantly different from that of the toothpaste  base at probability 0.05.
PENGEMBANGAN POTENSI RHODOMYRTONE SEBAGAI BAHAN AKTIF SEDIAAN TOPIKAL Fahmi, Rizal; Rullah, Kamal; Rahmat, Rosita Dewi; Lucida, Henny; Manjang, Yunazar; Hj. Lajisc, Nordin; Dachriyanus, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 1 (2012)
Publisher : Indonesian Research Gateway

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Abstract

Rhodomyrtone, an antibacterial constituent was isolated from the active fraction of theleaves extract of Karamuntiang, Rhodomyrtus tomentosa (Aiton) Hassk. In this presentstudy, the topical cream formula of rhodomyrtone 2% in vanishing cream was evaluated byin vitro and in vivo preclinical test. The in vitro test was peformed against Staphylococcusaureus ATTC 6538 and Staphylococcus epidermidis ATTC 12228 by using disk agardiffusion method, while the in vivo test was evaluated on the surface of skin infection area ofthe rabbit caused by Staphylococcus aureus. Both these tests were guided bychloromphenicol 2% cream as a comparison. The topical cream of rhodomyrtone 2% invanishing cream showed diameters of inhibition zones of 15 mm and 26 mm towardStaphylococcus aureus and Staphylococcus epidermidis respectively. These diffusions werelower than inhibition zones of chloromphenicol 2% cream which has 30 mm and 32 mm forthe same bacterias in the same condition. The in vivo test showed that rhodomyrtone 2%topical cream can reduced that skin infection and did not caused irritation on the testedrabbits.ABSTRAKRhodomyrtone adalah suatu konstituen antibakteri fraksi aktif ekstrak daun karamuntiang,Rhodomyrtus tomentosa (Ait) Hassk. Pada penelitian ini telah dilakukan uji preklinisterhadap krim sediaan topikal Rhodomyrtone 2% dalam vanishing cream. Uji preklinissecara in vitro menggunakan media agar dan Staphylococcus aureus ATTC 6538 danStaphylococcus epidermidis 12228 sebagai bakteri uji, sedangkan secara in-vivo dilakukanterhadap kulit pada kelinci yang di infeksi dengan Staphylococcus aureus. Kedua uji inimenggunakan krim kloromfenikol 2% sebagai pembanding. Krim sediaan topikalrhodomyrtone 2% dengan basis vanishing cream memberikan diameter hambatan berturutturut15 mm dan 26 mm terhadap Staphylococcus aureus dan Staphylococcus epidermidis.Difusi ini lebih rendah dibanding sediaan krim kloromfenikol 2% yang memberikan diameterhambatan 30 mm dan 32 mm, masing-masing untuk Staphylococcus aureus danStaphylococcus epidermidis pada kondisi yang sama. Selanjutnya uji secara in vivomenunjukkan bahwa krim sediaan topikal rhodomyrtone 2% dapat mengurangi infeksi kulitdan tidak menimbulkan iritasi pada kelinci percobaan.
Uji Sifat Fisikokimia Mocaf (Modified cassava Flour) dan Pati Singkong Termodifikasi untuk Formulasi Tablet Wira Noviana, Wira Noviana; Halim, Auzal; Lucida, Henny
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 6, No 3 (2013)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT: Utilization of cassava starch as an excipient in the tablet formulation is still very limited. Various modifications to the cassava starch has been carried out to obtain a better starch properties. The aim of this study was to examine the physi- cochemical properties of MOCAF and modified cassava starch as an excipient for tablet formulation, especially for direct compression method. MOCAF and modified cassava starch is a product of flour and cassava starch is modified mainly by lac- tic acid bacteria (Lactobacillus sp). Then the results of these modifications will be evaluated physicochemical properties, including examination of the surface shape of starch granules using SEM, thermal analysis by DTA, the pattern of starch crys- tallographic by X-ray diffraction, adsorption isotherm, and the content of amylose. The results showed that MOCAF and modified cassava starch granule were rougher- occurred some holes presented distinctively- and more crystalline than Starch 1500. Meanwhile, the result of adsorption isotherms MOCAF and modified cassava starch showed a model type II of adsorption isotherms. Another results show that the amy- lose content of cassava starch modified 48 hours has the highest amylose content that is equal to 33.5714%. Keywords: MOCAF, Modified Cassava Starch, Lactic Acid Bacteria, Tablets ABSTRAK: Penggunaan pati singkong sebagai bahan tambahan dalam formulasi tablet masih sangat terbatas. Berbagai modifikasi terhadap pati singkong telah dilakukan untuk mendapatkan sifat pati yang lebih baik. Tujuan penelitian ini adalah untuk menguji sifat fisikokimia MOCAF dan pati singkong termodifikasi sebagai bahan tambahan dalam formulasi tablet khususnya untuk metoda cetak langsung. MOCAF dan pati singkong termodifikasi merupakan produk tepung dan pati singkong yang dimodifikasi terutama oleh bakteri asam laktat (Lactobacillus sp). Kemudian hasil modifikasi ini akan dievaluasi sifat fisikokimianya, dianta- ranya pemeriksaan bentuk permukaan granula pati menggunakan SEM (Scanning Electron Microscope), analisis panas dengan DTA, pola kristalografi pati dengan difraksi sinar X, adsorpsi isoterm, dan kadar amilosa. Hasilnya menunjukkan bah- wa MOCAF dan pati singkong termodifikasi mengalami perlubangan pada permu- kaan granulanya, dan lebih bersifat kristal jika dibandingkan dengan Starch 1500. Sementara itu, dari hasil pemeriksaan adsorpsi isoterm MOCAF dan pati singkong termodifikasi menunjukkan model adsorpsi isoterm tipe II. Hasil lainnya menun- jukkan bahwa kadar amilosa pati singkong termodifikasi 48 jam mempunyai ka- dar amilosa paling tinggi yaitu sebesar 33,5714%. Kata kunci: MOCAF, Pati Singkong Termodifikasi, Bakteri Asam Laktat, Tablet
FORMULATION OF ANTI-PLAQUE TOOTHPASTE FROM STANDARDIZED GAMBIR EXTRACT AND ITS ANTIMICROBIAL ACTIVITY Lucida, Henny; Rustini, .; Saufitri, Dian; Dachriyanus, .
Jurnal Farmasi Indonesia Vol 5, No 2 (2010)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v5i2.40

Abstract

Telah dilakukan formulasi pasta gigi ekstrak gambir terstandarisasi serta uji daya antimikrobanya terhadap pertumbuhan bakteri penyebab plak Streptococcus mutans. Uji pendahuluan menunjukkan bahwa ekstrak gambir terstandarisasi pada kadar 7% memiliki diameter hambat optimal terhadap pertumbuhan mikroba uji. Berdasarkan ini dibuat 3 formula pasta gigi dengan kadar ekstrak gambir terstandarisasi sebesar 7% dengan kosentrasi kalsium karbonat (abrasif) yang bervariasi, berturut-turut 37, 42 dan 47%. Semua formula diuji sifat-sifat farmasetik dan aktivitas antimikrobanya, sebagai pembanding digunakan pasta gigi â??Fâ?. Hasil evaluasi sifat farmasetika sediaan menunjukkan semua formula memenuhi persyaratan pastagigi yang baik.  Formula 3 (F3) memberikan diameter hambat paling baik (19,25 + 0,50 mm), sedangkan pembanding â??Fâ? memberikan diameter hambat (20,0 + 0,00 mm).  Terdapat perbedaan bermakna diameter hambat antar perlakuan (basis versus pasta gigi ekstrak gambir) pada taraf kepercayaan  0,05.   ABSTRACT A toothpaste containing standardized gambir extract had been formulated and an antimicrobial assay of the toothpaste against Streptococcus mutans had been done. Preliminary study showed that the concentration of gambir extract of 7 % obtained an optimal range of inhibition of S. mutans growth. Three formulas were then prepared, which contained 7 % extract and various concentrations of calcium carbonate (37, 42 and 47 % respectively). The formulas were subjected to evaluation procedures including the pharmaceutical properties and the antimicrobial activity in comparison to commercial formula â??Fâ?. Results indicated that all formulas had good pharmaceutical properties. F3 showed the best inhibition against the growth of S mutans (diameter of inhibition =  19,25 + 0,50 mm) while that of the commercial toothpaste â??Fâ? was (20,0 + 0,00 mm) , which was significantly different from that of the toothpaste  base at probability 0.05.
PENGEMBANGAN POTENSI RHODOMYRTONE SEBAGAI BAHAN AKTIF SEDIAAN TOPIKAL Fahmi, Rizal; Rullah, Kamal; Rahmat, Rosita Dewi; Lucida, Henny; Manjang, Yunazar; Hj. Lajisc, Nordin; Dachriyanus, .
Jurnal Farmasi Indonesia Vol 6, No 1 (2012)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v6i1.93

Abstract

Rhodomyrtone, an antibacterial constituent was isolated from the active fraction of theleaves extract of Karamuntiang, Rhodomyrtus tomentosa (Aiton) Hassk. In this presentstudy, the topical cream formula of rhodomyrtone 2% in vanishing cream was evaluated byin vitro and in vivo preclinical test. The in vitro test was peformed against Staphylococcusaureus ATTC 6538 and Staphylococcus epidermidis ATTC 12228 by using disk agardiffusion method, while the in vivo test was evaluated on the surface of skin infection area ofthe rabbit caused by Staphylococcus aureus. Both these tests were guided bychloromphenicol 2% cream as a comparison. The topical cream of rhodomyrtone 2% invanishing cream showed diameters of inhibition zones of 15 mm and 26 mm towardStaphylococcus aureus and Staphylococcus epidermidis respectively. These diffusions werelower than inhibition zones of chloromphenicol 2% cream which has 30 mm and 32 mm forthe same bacterias in the same condition. The in vivo test showed that rhodomyrtone 2%topical cream can reduced that skin infection and did not caused irritation on the testedrabbits.ABSTRAKRhodomyrtone adalah suatu konstituen antibakteri fraksi aktif ekstrak daun karamuntiang,Rhodomyrtus tomentosa (Ait) Hassk. Pada penelitian ini telah dilakukan uji preklinisterhadap krim sediaan topikal Rhodomyrtone 2% dalam vanishing cream. Uji preklinissecara in vitro menggunakan media agar dan Staphylococcus aureus ATTC 6538 danStaphylococcus epidermidis 12228 sebagai bakteri uji, sedangkan secara in-vivo dilakukanterhadap kulit pada kelinci yang di infeksi dengan Staphylococcus aureus. Kedua uji inimenggunakan krim kloromfenikol 2% sebagai pembanding. Krim sediaan topikalrhodomyrtone 2% dengan basis vanishing cream memberikan diameter hambatan berturutturut15 mm dan 26 mm terhadap Staphylococcus aureus dan Staphylococcus epidermidis.Difusi ini lebih rendah dibanding sediaan krim kloromfenikol 2% yang memberikan diameterhambatan 30 mm dan 32 mm, masing-masing untuk Staphylococcus aureus danStaphylococcus epidermidis pada kondisi yang sama. Selanjutnya uji secara in vivomenunjukkan bahwa krim sediaan topikal rhodomyrtone 2% dapat mengurangi infeksi kulitdan tidak menimbulkan iritasi pada kelinci percobaan.
OPTIMASI KOMBINASI PENGHANCUR DAN PENGIKAT DALAM FORMULASI TABLET EKSTRAK ETANOL DAUN Eugenia cumini Merr. Lucida, Henny; Saputra, Harry; Arifin, Helmi
Jurnal Farmasi Indonesia Vol 4, No 3 (2009)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v4i3.19

Abstract

Preclinical studies of the aethanolic extract of the leaves of Eugenia cumini Merr (Jamblang, jambu kaliang) showed that it decreased the blood glucose level of mice at the doses of 50, 100 dan 200 mg/kg BW respectively. The extract was not toxic with the LD50 >15g/kg BB. The acute and sub-acute toxicity studies indicated that the extract was safe for a long use in mice. These results supported the potencial of this extract to be formulated as drug. This study reported the optimization technique used in the formulation of tablet of the aethanolic extract of Eugenia cumini Merr leaves to obtain best formulation with combination of dissintegrant and binder with respect to tablet dissintegration time. Four formulations containing  250 mg of extract were prepared by wet granulation. Results showed that granules of each formulas fulfilled the requirements of granules physical properties except granules a and b for its moisture content. The tablets also fulfilled the Indonesia Phamacopeia requirements except formula b for dissintegration time. Formulation of tablet based on optimization (amprotab 11% and PVP 2%) resulted in tablets with dissintegration time of 499 seconds (contour plot showed 443 seconds). ABSTRAK Uji preklinis menunjukkan bahwa ekstrak etanol daun Eugenia cumini Merr (Jamblang, jambu kaliang) dengan dosis 50, 100 dan 200 mg/kg BB dapat menurunkan kadar glukosa darah hewan percobaan. Ekstrak ini tergolong tidak toksik dengan LD50 >15g/kg BB. Uji toksisitas akut  dan toksisitas sub akut menunjukkan bahwa ekstraks ini aman digunakan dalam jangka waktu lama. Dengan demikian senyawa ini berpotensi untuk dikembangkan menjadi fitofarmaka. Makalah ini melaporkan hasil penelitian tentang optimasi kombinasi penghancur dan pengikat dalam formulasi tablet antidiabetes dari ekstrak etanol daun Eugenia cumini Merr. Dibuat empat formula tablet yang mengandung ekstrak sebesar 250 mg secara granulasi basah, dengan amprotab sebagai penghancur dan polivinilpirolidon (PVP) sebagai pengikat. Respon yang diukur adalah sifat fisik granul, sifat fisik tablet dan waktu hancur tablet. Hasil penelitian menunjukkan bahwa granul yang dihasilkan memenuhi persyaratan uji sifat fisik granul kecuali formula a dan b untuk uji kandungan lembab. Tablet yang dihasilkan memenuhi persyaratan tablet menurut Farmakope Indonesia kecuali formula b untuk waktu hancur tablet. Variasi konsentrasi amprotab berpengaruh dominan terhadap waktu hancur tablet dibandingkan dengan variasi konsentrasi PVP. Formulasi tablet ekstrak etanol daun Eugenia cumini Merr berdasarkan hasil optimasi (amprotab 11% dan polivinilpirolidon 2%) memberikan tablet dengan waktu hancur 499 detik.
Uji Sifat Fisikokimia Mocaf (Modified cassava Flour) dan Pati Singkong Termodifikasi untuk Formulasi Tablet Wira Noviana, Wira Noviana; Halim, Auzal; Lucida, Henny
Jurnal Farmasi Indonesia Vol 6, No 3 (2013)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (742.398 KB) | DOI: 10.35617/jfi.v6i3.380

Abstract

ABSTRACT: Utilization of cassava starch as an excipient in the tablet formulation is still very limited. Various modifications to the cassava starch has been carried out to obtain a better starch properties. The aim of this study was to examine the physi- cochemical properties of MOCAF and modified cassava starch as an excipient for tablet formulation, especially for direct compression method. MOCAF and modified cassava starch is a product of flour and cassava starch is modified mainly by lac- tic acid bacteria (Lactobacillus sp). Then the results of these modifications will be evaluated physicochemical properties, including examination of the surface shape of starch granules using SEM, thermal analysis by DTA, the pattern of starch crys- tallographic by X-ray diffraction, adsorption isotherm, and the content of amylose. The results showed that MOCAF and modified cassava starch granule were rougher- occurred some holes presented distinctively- and more crystalline than Starch 1500. Meanwhile, the result of adsorption isotherms MOCAF and modified cassava starch showed a model type II of adsorption isotherms. Another results show that the amy- lose content of cassava starch modified 48 hours has the highest amylose content that is equal to 33.5714%. Keywords: MOCAF, Modified Cassava Starch, Lactic Acid Bacteria, Tablets ABSTRAK: Penggunaan pati singkong sebagai bahan tambahan dalam formulasi tablet masih sangat terbatas. Berbagai modifikasi terhadap pati singkong telah dilakukan untuk mendapatkan sifat pati yang lebih baik. Tujuan penelitian ini adalah untuk menguji sifat fisikokimia MOCAF dan pati singkong termodifikasi sebagai bahan tambahan dalam formulasi tablet khususnya untuk metoda cetak langsung. MOCAF dan pati singkong termodifikasi merupakan produk tepung dan pati singkong yang dimodifikasi terutama oleh bakteri asam laktat (Lactobacillus sp). Kemudian hasil modifikasi ini akan dievaluasi sifat fisikokimianya, dianta- ranya pemeriksaan bentuk permukaan granula pati menggunakan SEM (Scanning Electron Microscope), analisis panas dengan DTA, pola kristalografi pati dengan difraksi sinar X, adsorpsi isoterm, dan kadar amilosa. Hasilnya menunjukkan bah- wa MOCAF dan pati singkong termodifikasi mengalami perlubangan pada permu- kaan granulanya, dan lebih bersifat kristal jika dibandingkan dengan Starch 1500. Sementara itu, dari hasil pemeriksaan adsorpsi isoterm MOCAF dan pati singkong termodifikasi menunjukkan model adsorpsi isoterm tipe II. Hasil lainnya menun- jukkan bahwa kadar amilosa pati singkong termodifikasi 48 jam mempunyai ka- dar amilosa paling tinggi yaitu sebesar 33,5714%. Kata kunci: MOCAF, Pati Singkong Termodifikasi, Bakteri Asam Laktat, Tablet
Co-Authors AA Sudharmawan, AA Anita Lukman Armenia, Armenia Auzal Halim Azhoma Gumala Ben, Elfi Sahlan Chris Deviarny Dachriyanus Dwi Novrianda Eka Putri, Desi Elfi Delita Elyunaida, Elyunaida Erizal Zaini Fahmy, Rahmi Fauzana, Annisa Fitri Handayani Fitri, Ema Furqan, Mainal Gio Vanny Yusuf Gusnelti, Yessi Helmi Arifin Hj. Lajisc, Nordin Hj. Lajisc, Nordin Hosiana, Vinny Husni, Patihul Intan Permata Sari Irfandy Soumariris Jannah, Yasmin Raudhatul Jonisa, Rahma Aprilya Kamal Rullah Khairunnisa Assyifa Salva M. Yogi Riyantama Isjoni Marlina Marlina Maya Sofiana Mita Restinia Muslim Suardi Netty Suharti Nola Florida Nova Syafni Okti Rahayu Asih Olivia Sedona Patihul Husni Pradifta, Reysa Prima Putra, Deddi Rahmat, Rosita Dewi Rahmat, Rosita Dewi Regina Handayani Handayani, Regina Handayani Riah Trisnawati Rizal Fahmi Rustini Rustini Saafrida - saafrida Saafrida Saafrida Saafrida, Saafrida saafrida, Saafrida - Safni Safni Salman - Salman Salman Salman Salman Salman Umar Salsabila, Amilia Saputra, Harry Saputra, Harry Sari, Aulia Desvita Saufitri, Dian Saufitri, Dian Sintia, Ulma Triswanto Sentat Vinny Hosiana Vinny Hosiana Vivi Muharmi Wasif Gillani S Wira Noviana, Wira Noviana Wira Noviana, Wira Noviana Yoneta Srangenge Yunazar Manjang Yuningzia, Vannesha Zahara Gayo Zifriyanthi Minanda Putri