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All Journal Jurnal Kesehatan Andalas Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Jurnal Respirologi Indonesia Jurnal Sehat Mandiri Bioscientia Medicina : Journal of Biomedicine and Translational Research Unri Conference Series: Community Engagement Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Respiratory Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Impresi Indonesia Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Jurnal Sains, Teknologi dan Kesehatan (Medical Scientific Journal) MESINA
Russilawati, Russilawati
Fakultas Kedokteran Universitas Andalas
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Respiratory Science

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Relationship Between D-Dimer, Albumin Levels, and Outcome of COVID-19 Patients at Dr. M. Djamil General Hospital, Padang Wahyudin, Hendris Utama Citra; Khairsyaf, Oea; Russilawati, Russilawati
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.128

Abstract

Background: Several studies have found an increase in D-dimer levels in patients who died from a severe clinical condition. COVID-19 exhibits multi-organ dysfunction through several markers, including decreased albumin levels. There were some studies that were interested in understanding how D-dimer and albumin levels relate to the outcomes of COVID-19 patients. The aim of this study was to investigate the relationship between D-dimer, albumin levels, and patient outcomes. Method: This was a cross-sectional study of all COVID-19 patients treated at Dr. M. Djamil General Hospital, Padang, from January 1st, 2021 to December 31st, 2021. Results: The majority of patients (40.71%) were in the group of 18 and 49 years old; more than half of the subjects (56.16%) were female; and obesity was the most common comorbidity (40.9%). The majority of the subjects (42.79%) had moderate clinical COVID-19. Higher D-dimer levels had a statistically significant independent relationship with unfavorable outcomes (P=0.0001). Lower albumin levels had a statistically significant independent relationship with unfavorable outcomes (P=0.0001). Higher D-dimer and lower albumin each contributed 12.6% to patient outcome. Increasing D-dimer levels per 1 ng/mL would increase the probability of an unfavorable outcome by 0.120 times, and on the other hand, increasing albumin levels per 1 g/dL would increase the probability of survival by 2.143 times. Conclusion: Higher D-dimer levels independently had a relationship with an unfavorable outcome. Higher albumin levels were independently related to a favorable outcome.
Co-Authors Adrifen Berti Akbar Afriani Afriani Afriani Afriani Afriwardi Afriwardi Ahmad Junaidi ALADIN ALADIN Almurdi Almurdi Alya Ramadhini Amirah Zatil Izzah Andani Eka Putra Angela, Sonnya Morisa Anindia Salwa Salsabila Asterina Beni Indra, Beni Chicy WIdya Morfi Defrin, Defrin Dessy Mirzati Dessy Mizarti Dewi Wahyu Fitrina Dhiaulhaq, Zalva Indira Diana Nur Asrini Dimas Bayu Firdaus Dimas Bayu Firdaus Dwitya Elvira, Dwitya Dya Mulya Lestari Efrida Efrida Efrida, Efrida Elizabeth Bahar Elsa Purnama Sari Elsa Purnama Sari Elsesmita Elsesmita Ermayanti, Sabrina Ermayanti, Sabrina Fathiyyatul Khaira, Fathiyyatul Fauzar Fauzar Fenty Anggraini Fenty Anggraininy Finny Fitry Yani Firdawati, Firdawati Gusti Revilla Hafis Herdiman Hana Novera Hanif, Rayhendra Hanum, Fathiya Juwita Herman, Deddy Ilham Ilmiawati, Ilmiawati Intan Permata Sari Syafrudin Irvan Madison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Irvan Medison Julizar Julizar Junaidi, Katerine Laisa Azka Lili Irawati Linosefa Linosefa Lusi Agustini Arda Masrul Basyar Masrul Basyar Milano, Ryan Suheil Mirtha Anggraeni Mohamad Reza Muhammad Fajri Mustika Dita Pradinda Netti Suharti, Netti Nofendra, Ade Oea Khairsyaf Oea Khairsyaf Oea Khairsyaf Oea Khairsyaf Oea Khairsyaf Povi Pada Indarta Pratama, Fadel Ahmad Putra, M Firas Riselo Putri, Biomechy Oktomalio Rahmadina, Rahmadina Rahmadina, Rahmadina Rawzan Abdul Aziz Rina Gustia Rizanda Machmud Rosfita Rasyid Roza Kurniati Sabrina Ermayanti Sabrina Ermayanti Sari Nikmawati Sari, Elsa Purnama Suyastri Suyastri Tuti Handayani Utami, Sherly Putri Wahyudin, Hendris Utama Citra Yati Ernawati Yessy Susanty Sabri Yessy Susanty Sabri Yose Ramda Ilhami Yuliarni Syafrita