Article Per Year (5 Year)
p-Index From 2021 - 2026
4.589
P-Index
This Author published in this journals
All Journal BALI MEDICAL JOURNAL (BMJ) Medicina journal of internal medicine E-Jurnal Medika Udayana International Journal of Integrated Health Sciences Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Mutiara Medika: Jurnal Kedokteran dan Kesehatan INDONESIAN JOURNAL OF PHARMACY The Indonesian Biomedical Journal Paediatrica Indonesiana JBN (Jurnal Bedah Nasional) Jurnal Penyakit Dalam Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Gema Wiralodra Neurologico Spinale Medico Chirurgico Journal of Clinical and Cultural Psychiatry Bioscientia Medicina : Journal of Biomedicine and Translational Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Eduvest - Journal of Universal Studies IJRETINA - International Journal of Retina Ophthalmologica Indonesiana International Journal of Psychology and Health Science
I Gde Raka Widiana
Departemen Penyakit Dalam, Fakultas Kedokteran, Universitas Udayana, Denpasar, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 87 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 87 Documents
Search

 5   6   7   8   9 
Apparent Diffusion Coefficient (ADC) Value on Magnetic Resonance Imaging (MRI) in Determining Breast Cancer and Determining Breast Cancer With Locally Advanced Expansion Mahautama, I Gusti Agung Putra; Sitanggang, Firman Parulian; Martadiani, Elysanti Dwi; Widiana, I Gde Raka
Eduvest - Journal of Universal Studies Vol. 5 No. 8 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i8.52064

Abstract

Breast cancer is the most common malignancy in women and a leading cause of cancer-related deaths in Indonesia. Early detection of the locally advanced stage is crucial for therapy selection and prognosis. This study evaluates the diagnostic value of the Apparent Diffusion Coefficient (ADC) from diffusion-weighted MRI (DWI) in detecting breast cancer and assessing local advancement. A retrospective design was used with 50 patients who underwent breast MRI at Prof. Dr. I.G.N.G Ngoerah Hospital, Denpasar. ADC values were compared with histopathology for cancer confirmation and surgical reports for staging. At a cut-off of 1.088 × 10⁻³ mm²/s, ADC demonstrated excellent performance in distinguishing cancer from non-cancer (sensitivity 100%, specificity 96%, PPV 96.1%, NPV 100%, LR+ 25, LR- 0.0, accuracy 98%). However, for detecting locally advanced disease (cut-off 0.815 × 10⁻³ mm²/s), performance was lower (sensitivity 61.5%, specificity 75%, accuracy 68%). These results emphasize ADC's reliability in diagnosing breast cancer but suggest limitations in staging, highlighting the need for multimodal imaging and clinical assessment integration to improve accuracy and guide treatment decisions.
THE DIFFERENCE OF QUALITY OF LIFE AND COGNITIVE FUNCTION BETWEEN PATIENTS WITH AND WITHOUT AGE-RELATED MACULA DEGENERATION (AMD) Kristianto, Bobby; Sukartini Djelantik, Anak Agung Ayu; Andayani, Ari; Putrawati Triningrat, Anak Agung Mas; Juliari, I Gusti Ayu Made; Widiana, I Gde Raka
International Journal of Retina Vol 4 No 2 (2021): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2021.vol004.iss002.168

Abstract

Introduction: To determine the difference in the quality of life and cognitive function in patients with and without AMD. Methods: This research is an observational analytic study, a prospective cross sectional study in the polyclinic of RSUP Sanglah, Denpasar. Result: Study samples’s total are 66 people selected by consecutive sampling with 33 people in the group with AMD, and 33 people in the group without AMD. The results of the study showed the average age of the group with AMD 68 years and the group without AMD 67 years old. Most of the male sex and residence in denpasar in both groups. Most AMD with the wet type by 60.6 %. On the measurement of quality of life, it showed decreasing in all subscale in the group with AMD compared to the group without AMD with total average 27.2 % and also decreasing in cognitive function measured by MMSE in the group of AMD compared to the group of non – AMD with 6.8%, even though the MMSE score of the groups are within normal limits. All these things stated significant differences (p<0.05) statistically. Conclusion: There are decreasing quality of life and cognitive function in AMD groupd compared to Non-AMD group which is needed more treatment and screening in the future.
The Association Between Vitreous Vascular Endothelial Growth Factor Levels with Visual Acuity Before and After Pars Plana Vitrectomy in Proliferative Diabetic Retinopathy Noviantari, I Gusti Agung Ratna; Suryathi, Ni Made Ari; Triningrat, A.A. Mas Putrawati; Widiana, I Gde Raka; Andayani, Ari; Jayanegara, I Wayan Gede; Pantjawati, Ni Luh Diah
International Journal of Retina Vol 7 No 2 (2024): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2024.vol007.iss002.257

Abstract

Introduction: Vascular endothelial growth factor (VEGF) plays a crucial role in the development of proliferative diabetic retinopathy. Elevated levels of VEGF in the vitreous have been found to be associated with the severity of ischemia and neovascularization, which can lead to a decline in visual acuity. This study aims to determine the association between vitreous VEGF levels and improvement in visual acuity before and after PPV in PDR patients. Methods: This research is an analytic observational study with a pre-post single group design. The subjects of this study were all PDR patients who received PPV therapy at three hospital in Bali Province, Indonesia. Consecutive sampling method were conducted. The independent variable is vitreous VEGF, whilst pre and post-PPV visual acuity is the outcomes. We performed mean comparison and multivariable statistical test using IBM SPSS version 25. Result: 45 people were included in this study. Improvement in visual acuity after PPV compared to before PPV with an average improvement of 0.54 logMAR (p=0.001). Based on the ANCOVA multivariate analysis, factors affecting visual acuity improvement after PPV were preoperative vision (p<0.001), postoperative vision (p<0.001), HbA1c level (p=0.036), and DM duration (p=0.024). There was no association between high vitreous VEGF levels and visual acuity improvement (PR=0.95; 95% CI=0.55-1.63;p=0.841). Conclusion: This study concluded that there is an association between PPV and visual acuity improvement. However, clinicians should be aware of several confounding factors that affect visual acuity improvement, including pre-PPV visual acuity, post-PPV visual acuity, duration of DM, and HbA1c level. There is no relationship between vitreous VEGF and visual acuity before and after PPV in PDR, but it is necessary to keep good records of lens status and intraocular pressure status. Further research is needed and the research time is extended to evaluate a better visual outcome.
The role of sodium-glucose transport Protein-2 (Sglt-2) inhibitor on albuminuria and the progressive of diabetic kidney disease Wilayadi, Ni Wayan Mirah; Widiana, I Gde Raka
Gema Wiralodra Vol. 14 No. 2 (2023): gema wiralodra
Publisher : Universitas Wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/gw.v14i2.466

Abstract

Diabetes mellitus (DM) is a non-communicable disease with an increasing incidence every year. Sodium-Glucose Transport Protein-2 (SGLT-2) inhibitors are a class of insulin-independent antidiabetic drugs that can reduce the incidence of kidney function damage. This study aimed to determine the role of SGLT-2 inhibitor therapy in preventing the incidence of albuminuria so that it can be used as a consideration for treatment applications in type 2 DM patients. This study used the literature review method. Stages in data collection using the PRISMA method from several Journal Databases based on inclusion and exclusion criteria. SGLT-2 inhibitors are antidiabetic drugs that can help glycemic control with a good safety profile. The effectiveness of SGLT2 inhibitor class drugs has been proven to reduce the occurrence of albuminuria and impact the progression of diabetic kidney disease. Further research can be carried out to prove the benefits of this modality comprehensively.
Lacticaseibacillus rhamnosus Probiotics Improve Fasting Blood Glucose, HOMA-IR, and Reduce Body Weight in Diabetic Rat Model Suastika, Arresta Vitasatria; Widiana, I Gde Raka; Kusuma, Anak Agung Ngurah Jaya; Fatmawati, Ni Nengah Dwi; Suastika, Ketut; Sujaya, I Nengah
The Indonesian Biomedical Journal Vol 17, No 1 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i1.3525

Abstract

BACKGROUND: Indonesian indigenous probiotics have been found to improve disruptions of tight junctions in the intestinal epithelium and reduce total cholesterol levels. Improvement in the tight junction could decrease the LPS level and further reduce the blood glucose and insulin resistance. The effects of indigenous Indonesian Lacticaseibacillus rhamnosus (Lr) probiotics on glucose metabolism and inflammatory marker levels in diabetic rats was studied to find if these probiotics are suitable as potential supplementation treatment in diabetes.METHODS: Sixteen female Wistar rats were induced with diabetes using streptozotocin and fed a high-fat, high-sucrose diet. The rats were separated into four groups: LrFBB81, LrFSMM22, LrSKG34, and a control group. Each intervention group got daily dosages of 1 mL probiotic suspensions containing 109 CFU/mL cells given orally for 14 days, whereas the control group received saline. Fasting blood glucose (FBG), insulin, homeostatic model assessment for insulin resistance (HOMA-IR), lipopolysaccharide (LPS), and body weight were evaluated.RESULTS: FBG was significantly reduced in LrFSMM22 group (Δ=120.75 mg/dL, p=0.035), while significant reduction was not observed from LrFBB81, LrSKG34, and control groups. No statistically significant differences were found in HOMA-IR before and after intervention in all groups, but Δ HOMA-IR from LrFSMM22 group was reduced more than the control group (-3.90 vs. 2.02, p=0.028). All groups showed no significant differences in LPS level, meanwhile statistically significant reduction in body weight was observed in all probiotic groups, LrFBB81 (Δ=-15.7 gram, p=0.040), LrSKG34 (Δ= -20.43 gram, p=0.006), and LrFSMM22 groups (Δ=-18.33 gram, p=0.037).CONCLUSION: The administration of L. rhamnosus could improve FBG, HOMA-IR, and reduce body weight without suppressing the LPS.KEYWORDS: diabetes, probiotic, Lacticaseibacillus rhamnosus, fasting blood glucose, HOMA-IR, lipopolysaccharide, insulin resistance
Diagnostic Value of Apparent Diffusion Coefficient (ADC) and Tumor Size Based on Magnetic Resonance Imaging (MRI) to Determine Malignant Posterior Fossa Brain Tumors in Children Santoso, Ivon Indriyanti; Anandasari, Pande Putu Yuli; Margiani, Ni Nyoman; Widiana, I Gde Raka
Eduvest - Journal of Universal Studies Vol. 5 No. 8 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i8.52020

Abstract

Posterior fossa tumors in children are a diagnostic challenge that requires early and appropriate treatment. This study aims to evaluate the diagnostic value of Apparent Diffusion Coefficient (ADC) and tumor size using Magnetic Resonance Imaging (MRI) in distinguishing malignant and benign tumors in the posterior fossa of children. The research method uses a retrospective approach with analysis of medical records of pediatric patients undergoing MRI and histopathology examinations at Ngoerah Hospital Denpasar. The results showed that the ADC value of ≤834.6 mm²/s had a sensitivity of 91.3%, a specificity of 70.3%, and an accuracy of 78.0%. Meanwhile, the tumor size >13.2 cm³ has a sensitivity of 91.3%, specificity of 51.8%, and accuracy of 68.0%. The combination of these two parameters resulted in a sensitivity of 87.5%, a specificity of 96.1%, and an accuracy of 92.0%, indicating a significant improvement in diagnostic accuracy. Thus, the simultaneous use of ADC values and tumor size is an effective approach in detecting malignant posterior fossa tumors in children, supporting more accurate diagnosis and appropriate clinical treatment.
RELATIONSHIP BETWEEN DEGREE OF OPTICAL NERVE DAMAGE ON LEVEL OF DEPRESSION AND ANXIETY PATIENT WITH PRIMARY GLAUCOMA: Oral Presentation - Observational Study - Resident SETIAWAN, I KADEK AGUS; Rahayu, Ni Kompyang; Ariani, Ni Ketut Putri; Widiana, I Gde Raka; Kusumadjaja, I Made Agus; Juliari, I Gusti Ayu Made
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qeatyj71

Abstract

Introduction & ObjectivesGlaucoma is one of the leading causes of irreversible global blindness and the second most commoncause of blindness in the world after cataracts. Depression and anxiety often occur in glaucomapatients when glaucoma is first diagnosed, the effect of decreased vision function in glaucoma, sideeffects of glaucoma therapy both medically and surgically and financial effects due to length oftreatment and loss of job due to limited vision. This study aims to determine the relationship of thedegree of optic nerve damage to the level of depression and anxiety in patients with primaryglaucoma. MethodsThis research is an analytic, prospective observational research with a cross-sectional studyapproach. The relationship between independent variables and dependent variables was analyzed. ResultsThe Man Whitney test found a significant difference in anxiety scores between the severe and mildto moderate groups with a p value of 0.020 . The ANCOVA test found that there was a relationshipbetween the degree of optic nerve damage in primary glaucoma and the level of anxiety aftercontrolling for control variables. ConclusionThis study can be concluded that there is a difference in the level of anxiety between the degree ofsevere and mild to moderate optic nerve damage. The level of anxiety itself corresponds to thedegree of damage to the optic nerve. The more severe the damage to the optic nerve, increased ofthe patient's anxiety score.
Co-Authors A. A. G. Oka, A. A. G. Ade Sinyo Aristantrisna Adnyani, Ni Made Dwi Agrasidi, Putu Anindya Ake, Anselmus Anak Agung Chris Tedy Pramana Anak Agung Gde Oka Anak Agung Wiradewi Lestari and N. Sutarka Anwar Santoso Ari Andayani Ariani, Ni Ketut Putri Arlene Elizabeth Padang Aslesa Wangpathi Pagehgiri Bagus Ngurah Putu Arhana Bambang Purwanto Budi Suprapti Christopher Ryalino Cokorda Bagus Jaya Lesmana Dedi Silakarma Desak Putu Puteri Diah Rahtini Desy Permatasari Dewa Nyoman Putra Adiwinata Dewi Catur Wulandari Dharmi Lestari, Ni Putu Djodi Sidartha E. Elyshanti Elizabeth Haryanti Elysanti Dwi Martadiani Feliciano Pinto, Feliciano Firman Parulian Sitanggang Firman Sitanggang Gede Andi Aditya Gede Sukma Pranata Darma Gede Wira Mahadita Gede Wirya Kusuma Duarsa Handayani, Putu Novi Hendra Koncoro Hendra S Hendra Salim Hizkia Robinson Junsen Lumban Gaol I Dewa Agung Sutanjaya Giri Nugraha I Dewa Nyoman Wibawa I G. N. Anom-Supradnya I G. N. M. Sugiana I Gede Aditya Krishna Santhi I Gede Hendra Sucipta I Gusti Agung Trisna Windiani I Gusti Kamasan Arijana I Gusti Ngurah Ketut Budiarsa I Gusti Ngurah Made Suwarba I Gusti Rai Putra Wiguna I K. Sudartana I Ketut Suastika I Ketut Suwiyoga I Ketut Wiargitha I Ketut Widiana I Made Adi Satria Darma I Made Agus Endra Permana I Made Arimbawa I Made Ayusta I Made Gede Widnyana I Made Kardana I Nengah Sujaya I Nengah Wiadnyana Steven Christian I Nyoman Adi Putra I Nyoman Semadi I Nyoman Wiryawan I Putu Budhiastra, I Putu I Putu Gede Budiana, I Putu Gede I Putu Gede Eka Ariawan Suyasa, I Putu Gede Eka Ariawan I Wayan Eka Sutyawan I Wayan Gede Jayanegara I Wayan Juli Sumadi I Wayan Putu Sutirta Yasa I Wayan Sudhana I Wayan Wita I Wayan Yudiana IBN Mahendra Ida Bagus Gede Suparyatha Ida Bagus Putra Pramana Ida Safitri IKG Suandi Imam Effendi Indira Prawita Martani Inez Kartika Jetty Kalembang Jod Loekman Jodhi S Loekman Jodi Sidharta Loekman Jodi SL Juliari, I Gusti Ayu Made Juliari, IGAM K Suwitra K. Suwitra Kadek Budi Santosa Ketu Suwitra Ketut Mulyadi Ketut Putu Yasa Ketut Rina, Ketut Ketut Suarta Ketut Suega Ketut Suwitra Ketut Tuti Parwati Merati Komang Ayu Witarini Kristianto, Bobby Kumbara, Cokorde Istri Yuliandari Krisnawardani Kusuma, Anak Agung Ngurah Jaya Kusumadjaja, I Made Agus Luh Gede Yuliadewi NS Luh Yeni Laksmi Luh Yeni Laksmini Made Agus Dwianthara Sueta Made Asih MADE RATNA SARASWATI . Made Satria Yudha Dewangga Made Widhi Asih Mahardani, Putu Nandika Tungga Yudanti Mahautama, I Gusti Agung Putra Maria, Dessy Marleen MOCHAMMAD THAHA Moestikaningsih ** Moestikaningsih . Monica Sampurna Ngakan Gede Dwija Hermawan Ni Made Amelia R. Dewi Ni Made Ari Suryathi Ni Made Dharma Laksmi Ni Made Putri Suastari Ni Nengah Dwi Fatmawati Ni Nyoman Margiani Ni Putu Sriwidyani Ni Wayan Anantika Riani Ni Wayan Winarti Noviantari, I Gusti Agung Ratna NP Veny Kartika Yantie Nyoman Maharmaya Nyoman Paramita Ayu Nyoman Srie Laksminingsih Nyoman Sutarka, Nyoman Oka Udrayana Ommy Agustriadi Pande Made Wisnu Tirtayasa Pande Putu Yuli Anandasari Pantjawati, Ni Luh Diah Patriawan, Putu Paulus Wiyono Pemayun, Cok Istri Dewiyani PITIKA ASPR Poerwono Rahardjo Pradnyana DS, Bagus Ari Prayuda, Prayuda Purnama Purnama Putrawati Triningrat, Anak Agung Mas Putu Astri Novianti Putu Ayu Saraswati Putu Junara Putra Putu Yuliawati Rahayu, Ni Kompyang Raka-Sudewi A. A. Reny Setya Pratiwi Duarsa Rully Roesli Santoso, Ivon Indriyanti Satrio Ryandi Semadhi, Putu Gitanjani Mahadewi Setiawan, I Gede Budhi Setiawan, I Kadek Agus Sianny Herawati Silvester Kristian Taopan Siska Sitanggang, Firman Parulian Soetjiningsih Soetjiningsih Suastika, Arresta Vitasatria Sudaryat S Sudjana, Karismayusa Sukartini Djelantik, Anak Agung Ayu Sukmawati, Nurindah Sutyawan, I Wayan Eka Tianing - Trianto Trianto Triningrat, A.A. Mas Putrawati W Sudhana W. G. Jayanegara Wayan Aryadana Wayan Aryadana Wayan Sudana Wayan Sudhan Wayan Sudhana Wilayadi, Ni Wayan Mirah Wiradharma, Ketut Gede Y. Saskia-Javi Yenny Kandarini Yoga Putra Yuliawati, Putu Yuriawantini - Zulfariska, Nony