Article Per Year (5 Year)
p-Index From 2021 - 2026
4.589
P-Index
This Author published in this journals
All Journal BALI MEDICAL JOURNAL (BMJ) Medicina journal of internal medicine E-Jurnal Medika Udayana International Journal of Integrated Health Sciences Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Mutiara Medika: Jurnal Kedokteran dan Kesehatan INDONESIAN JOURNAL OF PHARMACY The Indonesian Biomedical Journal Paediatrica Indonesiana JBN (Jurnal Bedah Nasional) Jurnal Penyakit Dalam Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Gema Wiralodra Neurologico Spinale Medico Chirurgico Journal of Clinical and Cultural Psychiatry Bioscientia Medicina : Journal of Biomedicine and Translational Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Eduvest - Journal of Universal Studies IJRETINA - International Journal of Retina Ophthalmologica Indonesiana International Journal of Psychology and Health Science
I Gde Raka Widiana
Departemen Penyakit Dalam, Fakultas Kedokteran, Universitas Udayana, Denpasar, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 87 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 87 Documents
Search

 4   5   6   7   8 
Diagnostic validity of Thoracic trauma severity score in patient with blunt thoracic trauma for predicting mortality rate Ngakan Gede Dwija Hermawan; I Nyoman Semadi; I Gede Raka Widiana; Desy Permatasari; Christopher Ryalino
Neurologico Spinale Medico Chirurgico Vol 2 No 1 (2019)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.314 KB)

Abstract

Introduction: The high incidence of blunt thoracic trauma is still a serious concern in emergency services. Mild to severe cases of blunt thoracic trauma that come to the emergency department are not those that can be considered simple but need to be reviewed for the possibility that can lead to the occurrence of advanced complications. This study aims to predict mortality in patient with blunt thoracic trauma with TTS (Thoracic trauma severity) score. Patients and Methods: This is a retrospective study with 52 subjects of blunt thoracic trauma patients treated at our University Hospital from January 2016 to May 2017. Eligible data were collected from medical record analyzed by receiver operating characteristics curve and cross tabulation. Results: The age of the subjects are 48.03±15.62, with male 42 subjects (80.8%) and female ten subjects (19.2%). The mean point of Thoracic trauma severity score (TTSS) was 8.32 ± SD: 2.69. The outcome was three patients dead (5.8%) and 49 patients discharged (94,2%). The sensitivity of TTSS 100 %, specificity 89.7%, positive predictive value (PPV) 37.5%, negative predictive value (NPV) 100%, and accuracy rate 90.3%. Highly sensitivity and specificity results for Thoracic Trauma Severity Score is valid for the screening of Blunt Thoracic Trauma. Conclusion: At 11.5 cut-off point, the TTSS was an excellent tool to predict the mortality rate of patients with blunt thoracic trauma. It has a 100% sensitivity and 89.7% specificity, as well as 37.5% PPV and 100% NPV.
Correlation of total ischemic time to creatinine serum level and resistive index value in kidney transplant Putu Astri Novianti; Gede Wirya Kusuma Duarsa; Gede Andi Aditya; Anak Agung Gde Oka; Kadek Budi Santosa; I Wayan Yudiana; Pande Made Wisnu Tirtayasa; Ida Bagus Putra Pramana; Yenny Kandarini; Wayan Sudana; Djodi Sidartha; Raka Widiana
Neurologico Spinale Medico Chirurgico Vol 3 No 2 (2020)
Publisher : Indoscholar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36444/nsmc.v3i2.109

Abstract

Background: The transient period when the kidney donor was extracted until being anastomosed (total ischemic time) will aggravate many putative molecular ischemic-reperfusion injury mechanisms. Several studies have reported the risk of delayed graft function development, which can be reflected by creatinine serum (Cr) level and resistive index (RI) value. This study aims to determine the correlation of total ischemic time to Cr levels reduction in one-month post-transplantation and RI value. Methods: This was a cross-sectional retrospective study involving subjects who underwent kidney transplantation in Sanglah General Hospital. In this study, the primary parameters were total ischemic time, Cr level, and RI value. The total ischemic time is calculated using a stopwatch intraoperatively. Cr level was obtained from blood examination, and RI value was obtained from the ultrasonography test. Data analysis was analyzed statistically using SPSS 24.0, and p < 0.05 was considered significant. Results: About 17 kidney transplant subjects were included in this study. The mean total ischemic time was 105 minutes and 43 seconds. There was an insignificant negative correlation between Cr level reduction and total ischemia time (r = -0.36; p = 0.89). An analysis of the correlation of total ischemic time and RI value, there was a linear correlation, but statistically insignificant (r = 0.11; p = 0.66). Conclusion: Total ischemic time has a negative correlation with post-transplant creatinine serum level and a positive correlation with the post-transplant resistive index value, but these results are not statistically significant.
Diagnostic Value of Gynecologic Ultrasonography as A Malignancy Predictor in Children's Ovarian Tumor Ni Made Putri Suastari; Pande Putu Yuli Anandasari; Putu Patriawan; Ni Nyoman Margiani; Firman Parulian Sitanggang; I Gde Raka Widiana
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 2 (2022): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i2.14389

Abstract

The incidence of ovarian malignancy is rare in children, with proportions between 16-55%. A gynecologic ultrasonography score is expected to increase accuracy and be able to diagnose malignancy earlier. By using a retrospective cross-sectional study design, this study is a diagnostic test to assess ultrasonography examination as a predictor of malignancy with histopathological examination as the gold standard. The study subjects were 45 children admitted from July 2017 to December 2020. Characteristics of the subjects were obtained from medical records, gynecologic ultrasonography images were accessed from PACS, and histopathological results were obtained from SIMARS. The gynecologic ultrasonography images were scored by two observers using a scoring table. Variables assessed consisted of inner wall structure, wall thickness, septa, morphology, tumor vascularization and ascites. The data will then be analyzed, determining the optimal cut-off score, sensitivity, specificity, accuracy, and positive and negative predictive value. AUC value of 0.92 using a cut-off ≥14 obtained 15 malignant subjects and 1 benign subject and resulted in a sensitivity of 78.9%, specificity of 96.2%, a positive predictive value of 93.8%, a negative predictive value of 86.2%, and accuracy of 88.89%. It can be concluded that the diagnostic value of gynecologic ultrasonography examination as a predictor of malignant ovarian tumors in children was remarkable.
Perbandingan efektivitas teknik modifikasi dan konvensional pada operasi open pyelolithotomy batu staghorn I Gede Hendra Sucipta; Anak Agung Gde Oka; I Gede Raka Widiana
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.328 KB) | DOI: 10.15562/ism.v10i1.318

Abstract

Background: Open pyelolithotomy for staghorn stone patient management has a high stone-free rate. The disadvantages of open pyelolithotomy include aesthetics and postoperative complications, so a breakthrough to reduce these complications is needed, which can be achieved by doing modified open pyelolithotomy.Objective: To compare the modified and conventional open pyelolithotomy techniques according to the duration of operation, the volume of surgical bleeding, pain, and post-operative drop in hemoglobin (Hb).Method: A quasi-experimental study with twenty-two samples of staghorn stone patients was collected from October 2016 to October 2017. Parametric tests were used as data were normally distributed and homogeneous. The independent t-test was used to compare each measured parameter according to the type of operation. Analysis of covariance (ANCOVA) was used to control the variables of age, gender, and body mass index (BMI).Result: The modified technique had a shorter operating duration than the conventional method (p < .05). The volume of surgical bleeding in the modified technique was lower compared to the conventional technique (p < .05). Pain scores in the modified technique were lower than the conventional technique (p <  .05). The drop in Hb levels in the modified technique was lower than the conventional technique (p < .05). Analysis using ANCOVA found that the type of operation has a direct effect on the duration of operation, volume of surgical bleeding, and post-operative pain.Conclusion: The modified open pyelolithotomy technique was more effective than the conventional open pyelolithotomy technique based on the duration of operation, the volume of surgical bleeding, and post-operative pain scale. In this study, it was found that the drop in Hb levels was not directly affected by the type of surgery.
Hubungan antara TIL (Tumor Infiltrating Lymphocyte) dan MAI (Mitotic Activity Index) dengan kejadian metastase kelenjar getah bening (KGB) aksila pada operable breast cancer di RSUP Sanglah, Denpasar. I Gede Aditya Krishna Santhi; I Nengah Wiadnyana Steven Christian; I Gede Raka Widiana
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.19 KB) | DOI: 10.15562/ism.v10i2.427

Abstract

Latar belakang: Kanker payudara merupakan penyakit yang menduduki urutan ketiga di Eropa dan United State sebagai jenis kanker yang menyebabkan kematian. Studi dua dekade terakhir mengungkapkan bahwa Tumor microenvironment (TME)juga merupakan penentu penting perilaku tumor.Tumor padat umumnya terdiri dari berbagai sel kekebalan tubuh, termasuk limfosit T dan B, sel NK, makrofag, dan neutrofil. Imunitas adaptif dan imunosupresi selalu menunjukkan tingkat ekspresi yang berbeda pada tumor, dan banyak gen kekebalan terkait dengan inflamasi. Interaksi antara sel imunitas menentukan induksi atau penghambatan perkembangan tumor, angiogenesis, dan metastasis. Sistem imunitas mempengaruhi surveillance pada pasien kanker. Proliferasi telah dikenali sebagai “hallmark” dari kanker dan merupakan faktor prognostik kanker. Evaluasi dari derajat proliferasi sel dalam jaringan tumor digunakan untuk menilai progresifitas tumor. Penilaian indeks mitosis telah digunakan sebagai “gold standard” dalam menilai agresivitas tumor. Maka dari itu, tujuan penelitian ini adalah untuk mengetahui hubungan respon imun pada tumor dalam hal ini sel Lymphocyte dan aktifitas pembelahan sel tumor dengan kejadian penyebaran kanker ke KGB aksila pada operable breast cancer di RSUP Sanglah Denpasar. Metoda:Lima puluh tiga sampel pasien kanker payudara post MRM (Modified Radical Mastectomy) yang berobat di RSUP Sanglah yang mempunyai catatan medis (data klinis, histopatologis), sampel dipilih secara eligible sampling pada rekam medis pasien di Bagian/ SMF Bedah Onkologi Fakultas Kedokteran Universitas Udayana RSUP Sanglah dari tahun 2016 sampai dengan 2018. Penelitian ini merupakan “Cross Sectional Analitik" hubungan antara TIL dan MAI dengan kejadian metastase KGB aksila pada pasien operable breast cancer     secara univariant, bivariat dan multivariant dengan menggunakan perangkat lunak SPSS 20 for windows. Hasil: menunjukkan analisa dengan uji Chi-square didapatkan pasien dengan low TIL (P= 0,627), intermediate TIL (P= 0,339) dan pasien dengan MAI  ≥ 25 /10 lp (P= 0,531), MAI 13-24 /10 lp (P= 0,531) tidak dijumpai adanya hubungan bermakna dengan kejadian metastase KGB aksila karena tidak signifikan secara statistika.  Simpulan:tidak dijumpai adanya hubungan bermakna, low dan intermediate TIL memiliki kecenderungan metastase KGB aksila pada Operable Breast Cancer lebih tinggi, dan dijumpai pula adanya kecenderungan makin tinggi MAI, semakin tinggi resiko metastase KGB aksila pada operable breast cancer di RSUP Sanglah Denpasar.Hubungan antara TIL (Tumor Infiltrating Lymphocyte) dan MAI (Mitotic Activity Index) dengan kejadian metastase kelenjar getah bening (KGB) aksila pada operable breast cancer di RSUP Sanglah, Denpasar.
Pengaruh kadar haemoglobin dan hematokrit dengan insiden kegagalan arteriovenous fistula pada pasien gagal ginjal kronik stadium V Satrio Ryandi; Ketut Putu Yasa; I Gede Raka Widiana
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.687 KB) | DOI: 10.15562/ism.v11i3.630

Abstract

Chronic Kidney Disease (CKD) is a disease that requires important attention. Chronic kidney failure is mentioned as kidney damage that occurs more or equal to 3 months in the form of abnormal structural or functional damage from the kidney with or without a decrease in GFR. Management of chronic renal failure is hemodialysis. Hemodialysis performed on patients with chronic renal failure requires appropriate vascular access.Method: This study involved 76 respondents with a cross-sectional observation design in patients with stage V chronic kidney disease in Sanglah Hospital Denpasar from January 2018 to December 2018 conducted by arteriovenous fistula, with an age range of 17 years to 65 years, who have undergone regular hemodialysis for more than 3 month and with complete medical records.Result: From this study it was found, characteristics based on age ? 55 years were 40 respondents (52.6%) and age <55 were 36 respondents (47.4%). Characteristics based on gender obtained male data as many as 43 respondents (56.6%) and women as many as 33 respondents (43.4%). Characteristics based on BMI obtained a median value of 26. Characteristics based on BMI ? 26 Kg / m2 were 39 respondents (51.3%) and BMI <26 Kg / m2 were 37 respondents (48.7%). Characteristics based on INR ? 1.2 were 10 respondents (13.2%) and INR 0.9-1.1 were 66 respondents (86.8%). Characteristics based on DM disease obtained with DM disease data as many as 17 respondents (22.4%) and without DM disease as many as 59 respondents (77.6%). Patients with hemoglobin hemoglobin levels <9.9 gr / dl with non-patent AVF 47 (73.4%) and ? 9.9 gr / dl with non-patent AVF 17 (26.6%) while hemoglobin levels <9, 9 gr / dl with patent AVF of 3 (25%) and ? 9.9 gr / dl with patent AVF of 9 (75%) [PR=1,4; IK1,07-1,91; p=0,001].Conclusion: Hemoglobin <9.9 associated with failure of AVF. Low hemoglobin is the most important risk factor for the occurrence of AVF failure in CRF patients. Hematocrit <29.18 related to AVF failure. Gagal Ginjal Kronik (GGK) merupakan penyakit yang memerlukan perhatian penting. Gagal ginjal kronik disebutkan sebagai kerusakan ginjal yang terjadi lebih atau sama dengan 3 bulan baik berupa kerusakan struktur atau fungsi yang abnormal dari ginjal dengan atau tanpa penurunan GFR yang dilakukan kepada pasien GGK memerlukan akses vaskular yang tepat.Metode: Penelitian ini melibatkan 76 responden dengan rancangan observasi crossectional pada pasien  gagal ginjal kronis stadium V di RSUP Sanglah Denpasar dari mulai bulan Januari 2018 sampai Desember 2018 yang dilakukan arteriovenous fistula, dengan rentang umur 17 tahun sampai 65 tahun, yang sudah menjalani hemodialisis regular lebih dari 3 bulan dan dengan catatan medis yang lengkap. Hasil: Karakteristik berdasarkan umur ? 55 tahun sebanyak 40 responden (52,6%) dan umur < 55 sebanyak 36 responden (47,4%). Karakteristik berdasarkan jenis kelamin didapatkan data laki-laki sebanyak 43 responden (56,6%) dan perempuan sebanyak 33 responden (43,4%). Karakteristik berdasarkan BMI didapatkan nilai median 26. Karakteristik berdasarkan BMI  ? 26 Kg/m2 sebanyak 39 responden (51,3%) dan BMI < 26 Kg/m2 sebanyak 37 responden (48,7%). Karakteristik berdasarkan INR  ? 1,2 sebanyak 10 responden (13,2%) dan INR 0,9-1,1 sebanyak 66 responden (86,8%). Karakteristik berdasarkan penyakit DM didapatkan data dengan penyakit DM sebanyak 17 responden (22,4%) dan tanpa penyakit DM sebanyak 59 responden (77,6%).  Pasien dengan kadar haemoglobin Haemoglobin < 9,9 gr/dl dengan AVF tidak paten sebanyak 47(73,4%) dan  ? 9,9 gr/dl dengan AVF tidak paten sebanyak 17(26,6%) sedangkan kadar haemoglobin < 9,9 gr/dl dengan AVF  paten sebanyak 3 (25%)  dan  ? 9,9 gr/dl dengan AVF  paten sebanyak 9 (75%) [PR=1,4; IK1,07-1,91; p=0,001].Simpulan: Hemoglobin < 9,9 berhubungan dengan kegagalan AVF. Haemoglobin yang rendah menjadi faktor risiko yang paling berperan terhadap terjadinya kegagalan AVF pada pasien GGK..Hematokrit < 29,18 berhubungan dengan kegagalan AVF. 
Perbedaan cost-effectiveness pengangkatan drain kurang dari 3 hari dengan lebih dari 3 hari pada modified radical mastectomy Dewa Nyoman Putra Adiwinata; Ketut Widiana; I Gde Raka Widiana
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (450.05 KB) | DOI: 10.15562/ism.v11i2.720

Abstract

Introduction: Modified radical mastectomy (MRM) is a therapeutic choice for operable breast cancer. The most frequent post-surgery complication is seroma formation, and this can be circumvented by the use of drainage. There is still a debate over the use of drainage time on the effectiveness and cost efficiency used. The purpose of this study is a more in-depth study of the cost-effectiveness of removing drainage in less than three days with more than three days, in patients post-MRM.Method: This research is a cost-effectiveness analysis using a decision tree, with a cross sectional analytic research design. Data collection was performed retrospectively by comparing direct medical cost to evaluate the difference in cost-effectiveness of drain removal for less than three days and for more than three days for modified radical mastectomy (MRM).Results: 36 samples were collected that met the exclusion and inclusion criteria, consisting of 19 samples in the group with drain removal ≤ 3 days, and 17 samples in the group with drain removal> 3 days. Analysis of the cost of removing the drain less than three days showed the average direct medical cost of the patient was Rp. 700,578.00. Whereas patients with drain removal for more than three days showed a direct medical cost of Rp. 981,000.00. The average difference in average cost-effectiveness ratio between the two groups is Rp. 2,599.00.Conclusion: In this study, patients with drain removal ≤ 3 days had better cost-effectiveness compared to drain removal> 3 days. Pendahuluan: Modified radical mastectomy (MRM) adalah pilihan terapi pada kanker payudara dapat dioperasi. Komplikasi pasca tindakan yang paling sering terjadi adalah terbentukya seroma, dan hal tersebut dapat disiasati dengan penggunaan drain. Masih terjadi suatu perdebatan terhadap lama pemakian drain terhadap efektifitas dan efisiensi biaya yang digunakan. Tujuan dari penelitian ini adalah pengkajian lebih mendalam tentang cost-effectiveness pada pengangkatan drain kurang dari tiga hari dengan lebih dari tiga hari, pada pasien pasca tindakan MRMMetode: Penelitian ini merupakan penelitian cost-effectivness analisis menggunakan decision tree, dengan rancangan metode penelitian analytic cross sectional. Pengambilan data dilakukan secara retrospektif dengan membandingkan direct medical cost (biaya medis langsung) untuk mengevaluasi perbedaaan cost-effectiveness pengangkatan drain kurang dari tiga hari dan lebih dari tiga hari pada modified radical mastectomy (MRM).Hasil: Dikumpulkan 36 sampel yang memenuhi kriteria ekslusi dan inklusi, terdiri dari 19 sampel pada kelompok dengan pengangkatan drain ≤ 3 hari, dan 17 sampel pada kelompok dengan pengangkatan drain > 3 hari. Analisis biaya pada pengangkatan drain yang kurang dari tiga hari menunjukkan rerata direct medical cost pasien adalah Rp. 700,578,00. Sedangkan untuk pasien dengan pengangkatan drain lebih dari toga hari menunjukkan direct medical cost sebesar Rp. 981.000,00. Rerata perbedaan average cost-effectiveness ratio antara kedua kelompok adalah Rp. 2,599,00.Simpulan: Pada penelitian ini didapatkan pasien dengan pengangkatan drain ≤ 3 hari memiliki cost-effectiveness lebih baik dibandingkan dengan pengangkatan drain > 3 hari.
Korelasi antara parameter faal hemostasis dan kadar serum laktat sebagai indikator mortalitas pada pasien multiple trauma di Rumah Sakit Umum Pusat Sanglah Denpasar, Bali-Indonesia Hizkia Robinson Junsen Lumban Gaol; Ketut Wiargitha; Gde Raka Widiana
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.017 KB) | DOI: 10.15562/ism.v11i2.726

Abstract

Background: Trauma is now the most frequent cause of death in the first four decades of life and is still a major public health problem in every country. Trauma that occurs often involves several regions of the body. This condition is called multiple trauma. In multiple trauma, coagulopathy often occurs. In the last four decades it was mentioned that in multiple trauma conditions also occur acidosis and coagulopathy which will also increase the mortality of multiple trauma patients with multiple trauma, serum lactate is superior to base deficit. The purpose of this study is to obtain the correlation of each prothrombin time (PT) value, activated partial prothrombin time (aPTT) value and international normalized ratio (INR) value with serum lactate levels as indicators of mortality in multiple trauma cases.Methods: This study was an observational study with an analytic cross-sectional design to determine the correlation between physiological parameters of hemostasis and serum lactate in multiple trauma patients.Results: From the 60 samples studied there were 43 male patients (71.7%) and 17 female patients (28.3%) with an average age of 37 ± 19.61 years. 7 (11.7%) cases died. Logistic regression test with each conducted on the APPT and INR variables and lactate levels obtained aPTT was the most influential risk factor for mortality with a p-value of 0.005 <0.05 OR 0.023 (CI 95%: 0.002-0.332)Conclusion: Serum lactate levels and physiological hemostasis are not only indicators that explain a patient in a state of shock, but can also be used as an indicator in determining morbidity and mortality in multiple trauma patients.Latar belakang : Trauma saat ini merupakan penyebab kematian paling sering dalam empat dekade pertama kehidupan dan masih menjadi masalah kesehatan masyarakat yang utama di setiap negara. Trauma yang terjadi seringkali melibatkan beberapa regio tubuh. Kondisi ini disebut dengan multipel trauma. Pada multipel trauma, sering terjadi koagulopati.  Pada empat decade terakhir disebutkan bahwa pada multipel trauma juga terjadi keadaan asidosis serta koagulopati yang juga akan meningkatkan mortalitas pasien multipel trauma multipel trauma, serum laktat lebih superior dibanding defisit basa. Tujuan dari penelitian ini adalah didapatkan korelasi masing – masing nilai prothrombin time (PT), nilai activated partial prothrombin time (aPTT) dan nilai international normalized ratio (INR) dengan kadar serum laktat sebagai indikator mortalitas pada kasus multipel trauma.Metode: Penelitian ini merupakan studi observasional dengan rancangan potong lintang analitik untuk mengetahui korelasi antara parameter faal hemostasis dan serum laktat pada pasien multiple trauma.Hasil: Dari 60 sampel yang diteliti dijumpai penderita laki-laki sebanyak 43 orang (71,7 %) dan perempuan 17 orang (28,3 %) dengan rata-rata usia 37 ± 19,61 tahun. Penderita yang meninggal sebanyak 7 (11,7%)  kasus. Uji regresi logistik dengan masing masing dilakukan pada variabel APPT dan INR serta kadar laktat didapatkan aPTT merupakan faktor risiko yang paling berpengaruh terhadap terjadinya mortalitas dengan p-value 0,005 < 0,05 OR 0,023 (IK: 0,002-0,322)Simpulan: Kadar serum laktat dan faal hemostasis tidak hanya sebagai indikator yang menerangkan pasien dalam keadaan syok, tapi juga dapat digunakan sebagai indikator dalam menentukan morbiditas dan mortalitas pada pasien multipel trauma.
The relationship between urine specific gravity, urine pH, and blood uric acid levels to the type of urinary stones of patients with urolithiasis at Sanglah Hospital, Bali, Indonesia Jetty Kalembang; Anak Agung Gde Oka; I Gede Raka Widiana
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.158 KB) | DOI: 10.15562/ism.v11i2.744

Abstract

Background: Urine specific gravity, urine pH, and blood uric acid levels are risk factors for urinary tract stones. The urinary tract stones are formed due to the concentration of a solute exceeds its ability to remain in solution, resulting in supersaturation and crystallization. This study aims to determine the relationship between urine specific gravity, urine pH, and blood uric acid levels to the urinary stone's types in patients with urolithiasis at Sanglah HospitalMethods: A retrospective cross-sectional study was conducted among 95 subjects by using secondary data from the medical records in the period June 2017-2018 at Sanglah Hospital. The urolithiasis patient who met the inclusion and exclusion criteria were enrolled in this study. Data were analyzed by the Mann-Whitney Test and Kruskal-Wallis Test using SPSS version 17 for Windows.Results: The average age was 55±11 years old. Most of respondents were male (70.5%), normal Body Mass Index (BMI) (89.5%), urine pH <7 (75.7%), and mixed type of urinary stones (48.4%). There was a statistically significant relationship between the type of uric acid stone (p=0.029), blood uric acid levels (p=0.003), phosphate stone type (p=0.026), and magnesium stone (p=0.010) with urine pH. Besides, there was a statistically significant relationship between ammonium stone and blood uric acid levels types (p=0.022). A statistically significant difference was also found between stone types based on urine pH (p=0.013) in multivariate analysis.Conclusion: There is a significant relationship between urine pH and stone type on the incidence of urolithiasis in Sanglah Hospital in June 2017-2018, thereby increasing the incidence of urolithiasis.
Faktor–faktor yang berhubungan dengan batu empedu pada Diabetes Melitus Tipe 2 (DMT2) di RSUP Sanglah, Bali, Indonesia I Dewa Agung Sutanjaya Giri Nugraha; Made Agus Dwianthara Sueta; I Gde Raka Widiana
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (330.868 KB) | DOI: 10.15562/ism.v11i3.809

Abstract

Background: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to impaired insulin secretion, insulin action, or both. The purpose of this study was to determine the risk factors for gallstones formation in patients with type 2 diabetes mellitus.Methods: This study was a cross-sectional retrospective study with analytic observational design. The study samples were taken using secondary data. The sample size was determined by consecutive non-probable sampling method. A total of 47 samples were included in this study. Data were analyzed using SPSS version 17 for Windows. Results: Sex (r=0.404; p=0.005), lipid profile (r=0.323; p=0.027), and HbA1c (r=0.431; p=0.002) had a moderate relationship with the incidence of gallstones. In addition, BMI had a strong relationship with the incidence of gallstones (r=0.528; p=0,000). However, the duration of DM (r=0.291; p=0.047) had a weak relationship with the incidence of gallstones. Multivariate results showed that patients with higher BMI were 10.9 times more likely to developed gallstones and it was the most dominant risk factor for gallstones.Conclusion: There were significant relationships between sex, BMI, lipid profile, HbA1c, duration of DM with the occurrence of gallstones. BMI was proved to be a dominant risk factor.  Latar Belakang: DM merupakan kelainan metabolik dengan ciri hiperglikemia akibat gangguan sekresi insulin, kerja insulin, atau keduanya. Tujuan penelitian untuk mengetahui faktor-faktor risiko terjadinya batu empedu pada pasien dengan diabetes melitus tipe 2.Metode: Penelitian ini menggunakan desain observasional analitik cross-sectional retrospektif dimana sampel penelitian diambil menggunakan data sekunder dalam satuan waktu tertentu. Sampel ditentukan secara consecutive non probable sampling yaitu setiap penderita DMT2 yang memiliki rekam medis dalam periode tahun 2018 di RSUP Sanglah pada periode penelitian diambil sebagai sampel. Sebanyak 47 sampel dilibatkan dalam penelitian ini. Data dianalisis dengan SPSS versi 17 untuk Windows.Hasil: Jenis kelamin (r=0,404; p=0,005), profil lipid (r=0,323; p=0,027), dan HbA1c (r=0,431; p=0,002) memiliki hubungan sedang bermakna dengan kejadian batu empedu. Selain itu, IMT memiliki hubungan yang kuat dengan kejadian batu empedu (r=0,528; p=0,000). Namun lama waktu DM (r=0,291; p=0,047) memiliki hubungan yang lemah dengan kejadian batu empedu. Hasil multivariat menunjukkan bahwa pasien dengan BMI tinggi 10,9 kali lebih mungkin mengembangkan batu empedu dan hal tersebut merupakan faktor risiko paling dominan untuk batu empedu.Kesimpulan: ada hubungan jenis kelamin, IMT, profil lipid, Hba1c, durasi DM dengan terjadinya batu empedu. IMT merupakan faktor risiko dominan.
Co-Authors A. A. G. Oka, A. A. G. Ade Sinyo Aristantrisna Adnyani, Ni Made Dwi Agrasidi, Putu Anindya Ake, Anselmus Anak Agung Chris Tedy Pramana Anak Agung Gde Oka Anak Agung Wiradewi Lestari and N. Sutarka Anwar Santoso Ari Andayani Ariani, Ni Ketut Putri Arlene Elizabeth Padang Aslesa Wangpathi Pagehgiri Bagus Ngurah Putu Arhana Bambang Purwanto Budi Suprapti Christopher Ryalino Cokorda Bagus Jaya Lesmana Dedi Silakarma Desak Putu Puteri Diah Rahtini Desy Permatasari Dewa Nyoman Putra Adiwinata Dewi Catur Wulandari Dharmi Lestari, Ni Putu Djodi Sidartha E. Elyshanti Elizabeth Haryanti Elysanti Dwi Martadiani Feliciano Pinto, Feliciano Firman Parulian Sitanggang Firman Sitanggang Gede Andi Aditya Gede Sukma Pranata Darma Gede Wira Mahadita Gede Wirya Kusuma Duarsa Handayani, Putu Novi Hendra Koncoro Hendra S Hendra Salim Hizkia Robinson Junsen Lumban Gaol I Dewa Agung Sutanjaya Giri Nugraha I Dewa Nyoman Wibawa I G. N. Anom-Supradnya I G. N. M. Sugiana I Gede Aditya Krishna Santhi I Gede Hendra Sucipta I Gusti Agung Trisna Windiani I Gusti Kamasan Arijana I Gusti Ngurah Ketut Budiarsa I Gusti Ngurah Made Suwarba I Gusti Rai Putra Wiguna I K. Sudartana I Ketut Suastika I Ketut Suwiyoga I Ketut Wiargitha I Ketut Widiana I Made Adi Satria Darma I Made Agus Endra Permana I Made Arimbawa I Made Ayusta I Made Gede Widnyana I Made Kardana I Nengah Sujaya I Nengah Wiadnyana Steven Christian I Nyoman Adi Putra I Nyoman Semadi I Nyoman Wiryawan I Putu Budhiastra, I Putu I Putu Gede Budiana, I Putu Gede I Putu Gede Eka Ariawan Suyasa, I Putu Gede Eka Ariawan I Wayan Eka Sutyawan I Wayan Gede Jayanegara I Wayan Juli Sumadi I Wayan Putu Sutirta Yasa I Wayan Sudhana I Wayan Wita I Wayan Yudiana IBN Mahendra Ida Bagus Gede Suparyatha Ida Bagus Putra Pramana Ida Safitri IKG Suandi Imam Effendi Indira Prawita Martani Inez Kartika Jetty Kalembang Jod Loekman Jodhi S Loekman Jodi Sidharta Loekman Jodi SL Juliari, I Gusti Ayu Made Juliari, IGAM K Suwitra K. Suwitra Kadek Budi Santosa Ketu Suwitra Ketut Mulyadi Ketut Putu Yasa Ketut Rina, Ketut Ketut Suarta Ketut Suega Ketut Suwitra Ketut Tuti Parwati Merati Komang Ayu Witarini Kristianto, Bobby Kumbara, Cokorde Istri Yuliandari Krisnawardani Kusuma, Anak Agung Ngurah Jaya Kusumadjaja, I Made Agus Luh Gede Yuliadewi NS Luh Yeni Laksmi Luh Yeni Laksmini Made Agus Dwianthara Sueta Made Asih MADE RATNA SARASWATI . Made Satria Yudha Dewangga Made Widhi Asih Mahardani, Putu Nandika Tungga Yudanti Mahautama, I Gusti Agung Putra Maria, Dessy Marleen MOCHAMMAD THAHA Moestikaningsih ** Moestikaningsih . Monica Sampurna Ngakan Gede Dwija Hermawan Ni Made Amelia R. Dewi Ni Made Ari Suryathi Ni Made Dharma Laksmi Ni Made Putri Suastari Ni Nengah Dwi Fatmawati Ni Nyoman Margiani Ni Putu Sriwidyani Ni Wayan Anantika Riani Ni Wayan Winarti Noviantari, I Gusti Agung Ratna NP Veny Kartika Yantie Nyoman Maharmaya Nyoman Paramita Ayu Nyoman Srie Laksminingsih Nyoman Sutarka, Nyoman Oka Udrayana Ommy Agustriadi Pande Made Wisnu Tirtayasa Pande Putu Yuli Anandasari Pantjawati, Ni Luh Diah Patriawan, Putu Paulus Wiyono Pemayun, Cok Istri Dewiyani PITIKA ASPR Poerwono Rahardjo Pradnyana DS, Bagus Ari Prayuda, Prayuda Purnama Purnama Putrawati Triningrat, Anak Agung Mas Putu Astri Novianti Putu Ayu Saraswati Putu Junara Putra Putu Yuliawati Rahayu, Ni Kompyang Raka-Sudewi A. A. Reny Setya Pratiwi Duarsa Rully Roesli Santoso, Ivon Indriyanti Satrio Ryandi Semadhi, Putu Gitanjani Mahadewi Setiawan, I Gede Budhi Setiawan, I Kadek Agus Sianny Herawati Silvester Kristian Taopan Siska Sitanggang, Firman Parulian Soetjiningsih Soetjiningsih Suastika, Arresta Vitasatria Sudaryat S Sudjana, Karismayusa Sukartini Djelantik, Anak Agung Ayu Sukmawati, Nurindah Sutyawan, I Wayan Eka Tianing - Trianto Trianto Triningrat, A.A. Mas Putrawati W Sudhana W. G. Jayanegara Wayan Aryadana Wayan Aryadana Wayan Sudana Wayan Sudhan Wayan Sudhana Wilayadi, Ni Wayan Mirah Wiradharma, Ketut Gede Y. Saskia-Javi Yenny Kandarini Yoga Putra Yuliawati, Putu Yuriawantini - Zulfariska, Nony