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Focus on the dabrafenib, vemurafenib, and trametinib in clinical outcome of melanoma: a systematic review and meta-analysis Ida Ayu Widya Anjani; Anak Agung Bagus Putra Indrakusuma; I Gede Krisna Arim Sadeva; Putri Ayu Wulandari; Luh Made Mas Rusyati; Prima Sanjiwani Saraswati Sudarsa; I Gede Putu Supadmanaba; Desak Made Wihandani
Bali Dermatology and Venereology Journal Vol. 3 No. 2 (2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v3i2.38

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Background: Melanoma is the most serious lethal skin cancer, affects the melanin producer cells (melanocytes). Surgery is the most common treatment, whereas for the advance stage the development of a treatment is recommended. BRAF (Dabrafenib and Vemurafenib) inhibitor or MEK inhibitor (Trametinib) is used as the most frequently targeted therapy of melanoma due to more than 80% patient with positive BRAF mutation. In this review, those treatments will be investigated systematically to identify their clinical outcome.Method: This systematic literature review (SLR) was performed from Cochrane, Science Direct, Google Scholar, and Pubmed. Cochrane Risk-of-Bias Tool RoB2 is used to assess RCT studies and New-castle Ottawa Scale Assessment to assess cohort studies by 3 different assessors. Data analysis was carried out by using Review Manager (RevMan 5.4). Heterogenicity test was assessed by I2  and Chi2 statisticResult: There are 20 studies used in this article (13 RCT and 7 cohorts). The overall survival (OS) and progression-free survival (PFS) of study that using targeted therapy (vemurafenib, trametinib, or dabrafenib) compare other therapies (chemotherapy, immunotherapy,etc) showed risk ratio (RR) was 1.12 (95%CI 1.07,1.17;  I2=100%; p<0,00001). The OS and PFS with monotherapy compare of vemurafenib, trametinib, or dabrafenib with combination therapy showed RR was 1.09 (95%CI.06,1.13;I2=99%; p<0,00001). Conclusion: BRAF and MEK targeted therapy has a good prognosis for a patient with a positive BRAF gene mutation and could be combined with other therapy for a better clinical outcome rather than monotherapy.Keyword: melanoma, dabrafenib, vemurafenib, and trametinib
Correlation between body mass index and waist circumference among diabetes mellitus patients in Denpasar, Bali Kausalya Neelamagam; Desak Made Wihandani
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.735 KB) | DOI: 10.15562/ism.v9i3.179

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Background: Obesity is one of the most important modifiable risk factors for type 2 diabetes. There are two types of obesity the general obesity which measured using the body mass index (BMI) and central obesity measured by using waist circumference (WC) or waist/hip ratio. This research aims to investigate the correlation between body mass index and waist circumference among diabetic patients in Indonesian population.Methods: The study was carried out using the cross-sectional plan, by analyzing the secondary data that was collected from previous research on diabetic patients that was conducted in Medical Faculty of Universitas Udayana, Bali. The research was done in 4 months from October 2015 - January 2016, and the data was categorized based on BMI, WC, gender, age, family history of diabetes and duration of diabetes mellitus.Results: On a total of 96 sample there were 5 (5.2%) were having general obesity BMI >30 kg/m2, while 61(63.5%) were having central obesity, where the WC measurement for a male was >102 cm and for a female was >88 cm. From the study, it proves that there was a strong correlation in between BMI and WC (r = 0.752, 𝑃 < 0.01). It indicates the correlation was positive and significant.Conclusions: It is concluded that people who have a higher BMI tend to have a higher waist circumference value and with that, both the BMI and WC strongly correlate. As a suggestion, it is recommended to conduct the study using primary data for future research
Prevalence of anemia on chronic kidney disease and its influenced factors in Sanglah General Hospital 2015-2017, Bali Rubahshini Gunaseelan; I Wayan Surudarma; Desak Made Wihandani; I Wayan Gede Sutadarma
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.311 KB) | DOI: 10.15562/ism.v11i1.247

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Background: Anemia is the most common disease among chronic kidney disease (CKD) patients. Its prevalence increased gradually as kidney function decreased. Globally, it affects 1.62 billion people, which corresponds to 24.8% of the population.Aim: To determine the prevalence of anemia on CKD and its influenced factors at Sanglah Hospital, Bali.Method: This was a descriptive design study conducted in Sanglah General Hospital, Denpasar, Bali from 2015 until 2017. Medical records of the patients became the secondary data for this research.Result: From 2015 to 2017, there were 384 cases of CKD and 95 were anemic in the hospital. The prevalence of this case was 24.7 %. The age group of 51 - 60 years had the highest case. The males majorly dominated anemia on CKD. Anemia in stage V of CKD patients was the highest, and it increased more significant as the stages worsen, and diabetes was the leading underlying disease among anemia in CKD patients followed by CVD and glomerulonephritis. The hemoglobin level mean and glomerular filtration rate was lower than the normal one.
Level of awareness of alzheimer’s disease among elderly people in Denpasar, Bali Sabrina Annamma Philip; Desak Made Wihandani; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.64 KB) | DOI: 10.15562/ism.v11i1.260

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Background: Alzheimer’s disease (AD) is a chronic, irreversible, progressive, neurodegenerative that slowly impair memory and thinking skills especially in elderly people. This study aims to determine the level of awareness of AD among elderly people in Denpasar, Bali.Methods: A descriptive cross-sectional study was conducted by using self–administered validated questionnaire to determine the level of awareness of Alzheimer’s disease among the elderly people in Denpasar, Bali. The level of awareness could be classified into high awareness (>80%), moderate awareness (50-79%) and low awareness (<50%)Results: There were 50 subjects with 50 years old or above enrolled in this study. Most of the respondents had low awareness (82%) to the AD. About 38% of elderly people knew about AD and 58% of respondents said losing memory is a common thing in old age. Low education was said responsible increasing the risk of AD (30%). Only about 24% answered depression was prone to AD. In addition, about 34% said there was no cure for Alzheimer’s disease.Conclusion: Level of awareness among elderly people towards Alzheimer’s disease was low and needed improvement. Development and execution of educational programs should be carried out to the public to expand knowledge and understanding about Alzheimer’s disease.
Prevalence of obesity and factors contributes to obese among medical student in Medical Faculty of Udayana University in 2016 Shenbagam Mahalingam; Desak Wihandani
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (189.693 KB) | DOI: 10.15562/ism.v9i3.288

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Background: Obesity is a medical condition in which excess body fat has accumulated to the extent that is may have a negative effect on health. The increased prevalence has been in the developed country and also in developing country.Methods: This is crossectional-descriptive research. 67 samples that met inclusion criteria were included in the research. Samples obtained using consecutive sampling technique. The sample divided into four categories; underweight, normal weight, overweight, and obeseResults: 26.9% were overweight, and 10.4% were obese with a total of 67 samples. Most of the sample who met obese criteria are male.Conclusions: Prevalence of obesity among medical students in Udayana University with results 26.9% overweight and 10.4% obesity out of 67 samples, meanwhile 47,8% represent normal weight, and 14.9% represent underweight. In the inactive category, there are 42 adolescents (62.7%) out of 67 samples. Only 25 (37.3%) out of 67 samples were active physically.
Hubungan jumlah konsumsi jeruk terhadap kejadian batu ginjal di RSUP Sanglah Denpasar Made Wahyu Krisnandewi; I Wayan Gede Sutadarma; Desak Made Wihandani
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.223 KB) | DOI: 10.15562/ism.v10i3.419

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Latar Belakang: Batu ginjal merupakan penyakit ketiga terbanyak di bidang urologi setelah penyakit kelenjar prostat dan infeksi saluran kemih. sitrat merupakan salah satu inhibitor yang penting dalam pengumpulan kalsium oksalat dan berhubungan dengan kejadian batu ginjal. Tujuan studi ini adalah mengetahui hubungan jumlah konsumsi jeruk terhadap kejadian batu ginjalMetode: Penelitian analitik dengan metode cross sectional (potong lintang) dan menggunakan data primer dan sekunder.  Pengambilan data dilakukan di Rumah Sakit Umum Pusat Sanglah dari Januari sampai dengan Oktober 2018. Sebanyak 93 data dikoleksi dan dianlisis univariat, bivariat dan multivariate. Univariat menggunakan uji frekuensi, normlaitas dan tabulasi silang. Uji korelasi dan chisquare sebagai uji bivariat dan uji multivarait menggunakan regresi logistikHasil: Subjek penelitian terdiri atas 66.7% laki-laki dan 33.3% perempuan. Jangkauan usia pada sampel berkisar antara 15 tahun hingga 87 tahun, dengan rerata usia 52.38 + 11.3 tahun. Jenis kelamin laki-laki menunjukkan kecenderungan untuk memiliki batu ginjal bilateral (r= -0,258; p= 0.019). Korelasi negatif antara konsumsi jeruk dan batu ginjal dan tidak signifikan secara statistik (r= -0.024; p=0.533). regresi logistic menunjukkan jenis kelamin memilki hubungan yang disignifikan (p=0.0021; IK95%: 0.07-0.83).Simpulan: Batu ginjal disebabkan multifaktorial dan konsumsi jeruk tidak berkorelasi secara stastitikIntroduction: Kidney stone is the third most common disease in the disease of urology after prostate gland disease and urinary tract infections. Citrate is one of the important inhibitors of accumulation of calcium oxalate and associated with the incidence of kidney stones. This study aimed to determine the relationship of the amount of orange consumption to the incidence of kidney stonesMethod: The research is an analytical study with the cross-sectional method and using either primary or secondary data. Data collection was collected at the Sanglah hospital from January until October 2018. 93 data were collected and analyzed by univariate, bivariate and multivariate. Univariate uses frequency test, normalization, and cross-tabulation. Correlation and chi-square test as a bivariate test and multivariate test using logistic regressionResult: The study subjects consisted of 66.7% men and 33.3% women. The age range in samples from 15 to 87 years, with mean 52.38 + 11.3 years. The male sex showed a tendency to occur bilateral kidney stones (r = -0.258; p = 0.019). The correlation between the consumption of oranges and kidney stones was negatively and not statistically significant (r = -0.024; p = 0.533). Logistic regression states sex was a significant relationship (p = 0.0021; IK95%: 0.07-0.83)Conclusion: Kidney stones were caused by multifactorial and consumption of citrus was not statistically correlated.
Pengaruh obesitas pada kualitas tidur mahasiswa Fakultas Kedokteran Universitas Udayana periode 2018 Yudha Anggoro Kawi; Desak Made Wihandani; I Wayan Surudarma
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.579 KB) | DOI: 10.15562/ism.v10i3.442

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Introduction: Increased obesity rates in adolescents can lead to the emergence of new risk populations for the occurrence of sleep disorders. The emergence of sleep disorders will have a direct impact on decreasing the quality of sleep. This study aims to determine the effect of obesity on the sleep quality of students of the Faculty of Medicine, Udayana University.Method: The study design was cross sectional analytic with a total sample of 74 students of the Medical Faculty of Udayana University (37 samples of the Body Mass Index (BMI) obesity and 37 samples of the normal BMI). Sample selection is done randomly. Measuring sleep quality was done through filling in the Pittsburgh Sleep Quality Index (PSQI) questionnaire and measuring obesity was done by calculating BMI. The answers to the questionnaire were scoring and based on the global score, sleep quality was categorized into poor and good sleep quality. The PSQI questionnaire also included questions about health problems experienced by students in the past month. Data analysis is presented in the form of tables and narratives.Result: The results showed that in the obese student group there were 22 samples with poor sleep quality (53.7%) and 15 samples with good sleep quality (45.5%). In the normal IMT student group there were 19 samples with poor sleep quality (46.3%) and 18 samples with good sleep quality (54.5%). In 20 students with health problems, there were 15 samples with poor sleep quality and 5 samples with good sleep quality. In 54 students without health problems, 26 samples with poor sleep quality and 28 samples with good sleep quality. Analysis using chi-square showed obesity did not have a significant effect on sleep quality (p = 0.483). There was a significant effect of health problems on sleep quality (p = 0.039).Conclusion: Conclusions of the study were obesity did not have a significant effect on the quality of sleep of students of the Faculty of Medicine, Udayana University.
Prevalensi hipertensi pada orang dewasa menengah dengan overweight di denpasar tahun 2018 Komang Erdwin Wicaksana; I Wayan Surudarma; Desak Made Wihandani
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.723 KB) | DOI: 10.15562/ism.v10i3.490

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Background: Hypertension is an increase in systolic and diastolic blood pressure that exceeds the normal limit. Overweight in middle-aged adults is caused by excessive amounts of fat cells due to excessive calorie intake early.Methods: This type of descriptive research is carried out by using a retrospective approach. Data collection starting from events that have occurred or are ongoing to do a description of general characteristics and specific variables of the study to answer the research objectives. Variables that have been recorded will be determined by the prevalence of hypertension and overweight. The subjects of the study were hypertensive patients in middle-aged with overweight based on data obtained from East Denpasar Puskesmas I. Sampling was done using a random sampling method.Results: The prevalence of hypertension in middle-aged adults with overweight in Denpasar in 2018 there were 36.1% of respondents with stage 1 hypertension and 18% of respondents with stage 2 hypertension, with the incidence of hypertension with overweight is highest in the age group 56 - 60 years, with a percentage of 62.5%.Conclusions: The number of hypertensive patients in middle-aged adults with overweight in women is higher than in men.Latar Belakang: Hipertensi adalah peningkatan tekanan darah systolic dan diastolic yang melewati batas normal. Overweight pada dewasa menengah disebabkan oleh jumlah sel lemak yang berlebihan karena pemberian kalori yang berlebihan sejak dini.Metode: Jenis penelitian ini adalah deskriptif dilakukan dengan menggunakan pendekatan retrospektif. Subyek penelitian adalah penderita hipertensi pada dewasa menengah dengan overweight berdasarkan data yang diperoleh dari Puskesmas I Denpasar Timur. Pengambilan sampel dilakukan dengan menggunakan metode random sampling.Hasil: Prevalensi hipertensi pada orang dewasa menengah dengan overweight di Denpasar tahun 2018 terdapat 36,1% responden dengan hipertensi stadium 1 dan 18% responden dengan hipertensi stadium 2, dengan angka kejadian hipertensi dengan overweight paling tinggi pada kelompok umur 56 – 60 tahun, dengan persentase sebesar 62,5%.Simpulan: Jumlah pasien hipertensi pada orang dewasa menengah dengan overweight pada wanita lebih tinggi dibandingkan pria.
Hubungan indeks massa tubuh (IMT) terhadap kejadian psoriasis: sebuah tinjauan sistematik Christine Beatrice Amesiella; Desak Made Wihandani; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (765.765 KB) | DOI: 10.15562/ism.v12i1.925

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Background: Psoriasis is a chronic inflammatory disease associated with body mass index (BMI)  25 or obesity. This study aimed to look at the association between BMI and the incidence of psoriasis.Methods: This systematic review is done due to PRISMA statement guidelines. The search was conducted in Pubmed and PubMed Central database from 2015-2019 with inclusion age >18, BMI  25 and the results of Hazard Ratio (HR) and Odds Ratio (OR). The title and abstract of these articles were reviewed for relevance, based on inclusion criteria. This systematic review uses STROBE to evaluate the individual study's quality, which consists of 22 domains.Results:  In the final stage, this systematic review identifies four articles. Overall, the quality of these four articles based on the STROBE checklist is pretty good.  As much as two studies supported the association between BMI and psoriasis, the other two studies did not have any association.Conclusion: Overall, this systematic review shows that older age is found to have a higher effect on psoriasis. However, studies that support the existence of an association have incomplete control variables that can potentially lead to bias. Until now, the correlation between BMI and psoriasis remains unclear since many articles show contradicting results Latar Belakang: Psoriasis merupakan salah satu penyakit inflamasi kulit autoimun, bersifat kronik yang berhubungan dengan indeks massa tubuh (IMT)  25 atau obesitas. Tujuan dari penelitian ini adalah untuk melihat hubungan antara IMT dan kejadian psoriasis.Metode: Penulisan tinjauan sistematik ini dilakukan berdasarkan pedoman PRISMA. Pencarian artikel dilakukan pada database Pubmed dan PubMed Central dari tahun 2015-2019 dengan kriteria inklusi >18 tahun, IMT 25 dan hasil Hazard Ratio (HR) dan Odds Ratio (OR). Judul dan abstrak ditinjau berdasarkan relevansi penelitian. Penilaian kualitas studi dilakukan berdasarkan checklist STROBE yang terdiri dari 22 domain.Hasil: Pada tahap akhir didapatkan sebanyak empat artikel. Secara umum kualitas studi keempat artikel berdasarkan checklist STROBE cukup baik. Studi yang mendukung hubungan antara IMT dan psoriasis sebanyak dua dan yang tidak mendukung sebanyak dua.Kesimpulan: Tinjauan sistematik ini menunjukan bahwa faktor usia lebih tua ditemukan pengaruh yang lebih tinggi terhadap psoriasis. Namun, artikel yang mendukung adanya hubungan antara IMT dan psoriasis memiliki variabel kontrol yang tidak lengkap sehingga berpotensi bias. Sampai saat ini hubungan antara IMT dan psoriasis belum didukung oleh bukti yang kuat, karena dari artikel-artikel yang tersedia masih banyak yang bertentangan.
Obesitas sebagai faktor risiko terjadinya peningkatan kadar trigliserida dalam darah: tinjauan pustaka Baiq Rissa Khaerawati Salim; Desak Made Wihandani; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 12 No. 2 (2021): (Available Online: 1 August 2021)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (479.946 KB) | DOI: 10.15562/ism.v12i2.1031

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Obesity is considered a major factor in the emergence of various diseases such as coronary heart disease, stroke ischemia, and type 2 diabetes mellitus in developed and developing countries. Obesity is defined as an increase in body weight above 20% of normal limits and is associated with abnormal serum lipoprotein levels. Obese people are more at risk for diseases such as Diabetes Mellitus type 2, stroke and other diseases. Excessive fat accumulation in obese people results in increased amounts of free fatty acids hydrolyzed by endothelial lipoprotein lipases. This increase triggers the production of oxidants that have a negative effect on the endoplasmic reticulum and mitochondria. The free fatty acids released due to excessive fat accumulation also inhibit lipogenesis, resulting in an increase in triglyceride levels in the blood. This literature study aims to determine whether obesity is a risk factor for increased blood triglyceride levels based on the relevant literature.  Obesitas dianggap sebagai faktor utama munculnya berbagai macam penyakit seperti penyakit jantung koroner, stroke iskemik, dan diabetes mellitus tipe 2 yang terjadi di negara maju maupun negara berkembang. Obesitas diartikan sebagai peningkatan berat badan di atas 20% dari batas normal dan berhubungan dengan kadar lipoprotein serum tidak normal. Orang obesitas lebih berisiko untuk mengalami penyakit seperti Diabetes Mellitus tipe 2, stroke dan penyakit lainnya. Penumpukan lemak yang berlebihan yang terjadi pada orang obesitas mengakibatkan meningkatnya jumlah asam lemak bebas yang dihidrolisis oleh lipoprotein lipase endotel. Peningkatan ini memicu produksi oksidan yang berefek negatif terhadap retikulum endoplasma dan mitokondria. Asam lemak bebas yang dilepaskan karena adanya penimbunan lemak yang berlebihan juga menghambat terjadinya lipogenesis sehingga mengakibatkan peningkatan kadar trigliserida dalam darah. Tinjauan pustaka ini bertujuan untuk mengetahui apakah obesitas sebagai faktor risiko peningkatan kadar trigliserida dalam darah berdasarkan pada studi literatur yang relevan.
Co-Authors Adi Saputra Adioka GM Agung Nova Mahendra AGUS BAGIADA NYOMAN Anak Agung Bagus Putra Indrakusuma Anak Agung Bagus Putra Indrakusuma Anak Agung Gede Eka Septian Utama Anak Agung Istri Shania Kemala Anak Agung Ngurah Krisnanta Adnyana Ananta Kusuma, , I Komang Wira Andrean Heryanto Anjani, Ida AyuWidya Anthony Wijaya Arcana N Arim Sadeva, I Gede Krisna Artha, I Wayan Windi Atmaja, Made Ayu Kurniati Avissia Zivanna Bagus Komang Satriyasa Baiq Rissa Khaerawati Salim Bramantya, Putu Arya Rahadi Christian Chandra Christine Beatrice Amesiella Cokorda Bagus Jaya Lesmana Dady Iskandar Dhananjaya, I Gede Arya Diva Edgar, Christine Gede Andry Nicolas Andry Nicolas Halim, Wilson I A Md Dwi Purwitasari I Dewa Putu Sutjana I G. P. Supadmanaba I Gede Krisna Arim Sadeva I Gede Krisna Arim Sadeva I Gede S Narayana I Gede Wikania Wira Wiguna I Gusti Ayu Artini I Gusti Ayu Stiti Sadvika I Kadek Arya Gangga Permana I Ketut Agus Somia I Komang Wira Ananta Kusuma I Made Adi Widiantara I Made Angga Sayoga I Made Jawi I MADE MULIARTA . I Nyoman Wande I W. Sudarsa I Wayan Gede Sutadarma I Wayan Gede Sutadarma I Wayan Gede Sutadarma I Wayan Gede Sutadarma I Wayan Surudarma I Wayan Weta I Wayan Windi Artha I.A. Pascha Paramurthi Ida Ayu Dewi Wiryanthini Ida Ayu W Anjani Ida Ayu Widya Anjani Ida AyuWidya Anjani Ida Sri Iswari Indra Lesmana Indrakusuma, Anak Agung Bagus Putra Janet Tee Jaya, Ni Komang Ayu Amanda Setiari Katrin ** Kausalya Neelamagam Ketut Agus Adrianta Ketut Ayu Hartarani Prasetya Ketut Tirtayasa Komang Erdwin Wicaksana Kusumadewi, Made Dea Avrilia Listya Triandari Luh Made Indah Sri Handari Adiputra Luh Made Mas Rusyati Luh Putu Ratna Sundari M.Ali Imron Made Ngurah Arya Diningrat Pinatih Made VW Yani Made Wahyu Krisnandewi Mamangdean, Christo Timothy Marcella, Marzha Muh. Ali Imron Muhammad Ali Imron Muhammad Irfan Muhammad Irfan Ni Kadek Fiora Rena Pertiwi Ni Kadek Yudit Erawati Ni Made Ari Purwaningrum Ni Made Ayu Adnyani Ni Made Dwi Putri Nadi Ni Made Suasti Wulanyani Ni Nyoman Ayu Dewi Ni Nyoman Ayu Dewi Ni Nyoman Ayu Dewi Ni Nyoman Ayu Dewi Ni Nyoman Ayu Dewi Ni Putu Sri Indrani Remitha NN Ayu Dewi NYOMAN AGUS BAGIADA Nyoman Bayu Mahendra Parisya Sasmana, I Gede Aswin Prima Saraswati Sanjiwani Sudarsa Purwaningrum, Ni Made Ari Putri Ayu Wulandari Putri Ayu Wulandari Putri Ayu Wulandari, Putri Ayu Putu Anda Tusta Adiputra Putu Astawa Rubahshini Gunaseelan Ruma, I Made Winarsa Sabrina Annamma Philip Sasmana, I Gede Aswin Parisya Shenbagam Mahalingam Sinta Wiranata Sugijanto - Sugijanto - Surudarma, I Wayan Susy Purnawati Sutedja, Jane Carissa Tjokorda Gde Bagus Mahadewa Triana Devy, Anggi Amanda Widya Anjani, Ida Ayu Wijaya, Audrey Rachel Wijaya, Grace Veronika Wiranata, Sinta Yudha Anggoro Kawi