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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Biomedical Journal of Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Journal of Islamic Nursing Jurnal Kreativitas PKM SRIWIJAYA JOURNAL OF MEDICINE Jurnal Kesehatan Medica Hospitalia Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Pengabdian Masyarakat: Humanity and Medicine Indonesian Community Empowerment Journal International Archives of Medical Sciences and Public Health International Journal of Islamic and Complementary Medicine Journal of Child, Family, and Consumer Studies Mega Buana Journal of Innovation and Community Service (JICS) Jurnal Profesi Guru Indonesia
Evi Lusiana
Department Of Pharmacology, Faculty Of Medicine, Sriwijaya University, Palembang, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Counseling of the Use of Herbal Medicines for Health Care to the Community Parisa, Nita; Kamaluddin, M. T.; Theodorus; Saleh, Mgs. Irsan; Lusiana, Evi; Tamzil, Nia Savitri; Wicaksono, Bonanza Abi; Nashif, Arkan Abdullah
Indonesian Community Empowerment Journal Vol. 2 No. 2 (2022): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v2i2.21

Abstract

Herbal medicine is growing quite rapidly, especially in every area that has traditional medicine using natural ingredients that are believed to treat disease. In addition, the use of herbal medicines is believed to have fewer side effects compared to conventional medicine. WHO also recommends the use of traditional and herbal medicines in efforts to maintain health, as well as prevent and treat diseases ranging from mild to chronic diseases. Based on the various problems faced, the purpose of implementing community service is to increase public knowledge and understanding of medicinal plants, independent health screening, and self-medication, and the role of supplements (vitamins and herbs) in health care and disease prevention efforts.
Potency of Karamunting (Rhodomyrtus tomentosa) Leaf Extract as Antidiabetic for Type 2 Diabetes: A Systematic Review Sutandar, Vivi Hendra; Saleh, M. Irsan; Lusiana, Evi; Parisa, Nita; Tamzil, Nia Savitri
Biomedical Journal of Indonesia Vol. 11 No. 3 (2025): Vol 11, No 3, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i3.273

Abstract

Type 2 diabetes mellitus (T2D) is a chronic metabolic disorder characterized by reduced insulin sensitivity and inadequate insulin secretion, leading to elevated blood glucose levels. Standard treatment relies on synthetic drugs, which can cause adverse effects in some patients. Rhodomyrtus tomentosa, a plant native to Indonesia and widely used in traditional medicine, is being explored as a natural alternative for diabetes management due to its potential antidiabetic properties. This review compiles recent findings on its therapeutic potential. A systematic literature search was conducted in August 2024 in PubMed, Wiley Online Library, ScienceDirect, Cochrane Library, ProQuest, and Google Scholar using the keywords “Rhodomyrtus tomentosa” and “antidiabetic.” Of 774 screened articles, five met the inclusion criteria (2014–2024). The studies employed in vitro, in vivo, and in silico approaches, focusing mainly on fruits and leaves. Results indicate that R. tomentosa may help control blood glucose by inhibiting α-glucosidase and α-amylase, enzymes critical in carbohydrate digestion. Bioactive compounds such as phloroglucinols and meroterpenes were frequently identified. However, most evidence comes from laboratory models, with limited animal research and no clinical trials. The risk of bias was moderate, often due to incomplete reporting. While findings suggest R. tomentosa is a promising natural candidate for diabetes treatment, its therapeutic value remains unconfirmed. More robust in vivo studies and human clinical trials are essential to clarify its mechanisms, safety, pharmacokinetics, and efficacy. This review serves as a basis for future research and highlights the need for rigorous studies to validate its clinical potential.
Profile of Nutritional Status Based on Chemotherapy Regimen and Cycle in Colorectal Cancer Patients at Dr. Mohammad Hoesin Hospital Palembang Muhammad, Fadhil; Manawan, Efman E.U.; Kurniati, Ardesy Melizah; Komar, Muhammad Hafidh; Lusiana, Evi; Adenina, Syarinta
Sriwijaya Journal of Medicine Vol. 8 No. 2 (2025): Vol 8, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v8i2.228

Abstract

A cancerous growth that develops from the colon's or rectum's epithelial tissue is called colorectal cancer.  Chemotherapy is one of the interdisciplinary approaches used to treat colorectal cancer.  Chemotherapy is administered in cycles of one to eight.  One of the many adverse consequences of chemotherapy is a decline in nutritional status.  In this study, colon cancer patients receiving chemotherapy at Dr. Mohammad Hoesin Hospital Palembang will have their nutritional status described using BMI.  It was a descriptive investigation. The most recent medical records of colorectal cancer patients who visited Dr. Mohammad Hoesin Hospital Palembang for chemotherapy were used to gather data. Of the 44 patients, the majority were equally male and female (50%), middle-aged (52.3%), had colon cancer (50%), were in stage IV (75%), had undergone chemotherapy cycle 2 (34.1%), were on the FOLFOX 6 regimen (27.3%), and were well-nourished (50%). The majority of the study's patients were normoweight individuals, undergoing chemotherapy cycle 2, and were on the FOLFOX 6 regimen.
Activity of Karamunting Leaf Extract (Rhodomyrtus tomentosa (Aiton) Hassk) as an Antibiofilm on Klebsiella pneumoniae Sabrina, Tia; Simanjuntak, Ricardo; Rivani, Erizka; Zanaria, Rima; Lusiana, Evi
Jurnal Kesehatan Vol 16 No 2 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i2.4982

Abstract

Klebsiella pneumoniae can cause serious infections. The use of antibiotics is often an option in treating infections, but bacteria can adapt by forming biofilms. Therefore, the search for alternative antibiofilms from natural sources is important. One potential plant is karamunting leaves (Rhodomyrtus tomentosa (aiton) hassk). This study aims to describe the potential of the ethanol extract of karamunting leaf as an antibiofilm against Klebsiella pneumoniae. This study is an in vitro descriptive laboratory test. A thick ethanol extract of karamunting leaves was then prepared in three concentration variations: 62.5µg/mL, 125µg/mL, and 250µg/mL. The positive control used was meropenem, and the negative control used was DMSO. The parameter measured for the inhibition and eradication test was biofilm thickness, which was read using a 590nm Microplate reader. In this study, the percentage of inhibition in the three concentrations was 90.65% at a concentration of 250 µg/ml, 86.69% at a concentration of 125µg/ml, and 87.22% at a concentration of 62.5µg/ml. During the eradication test, the percentages obtained were -10.67% at a concentration of 250µg/ml, 3.58% at a concentration of 125µg/ml, and 68.23% at a concentration of 62.5µg/ml. The ethanolic extract of karamunting leaves demonstrates good biofilm inhibitory activity against Klebsiella pneumonia at all tested concentrations. At a concentration of 62.5µg/ml, the extract exhibits good biofilm eradication activity, while at 125µg/ml and in the positive control, it shows poor activity. Interestingly, at a concentration of 250µg/ml, the extract acts as a biofilm promoter, enhancing biofilm formation.
Cemilan Sehat Ibu Hamil Bisikoik Lekok Kelorok sebagai Pencegahan Stunting di Kelurahan Bontonompo Selatan Kab. Gowa Muaningsih, Muaningsih; Lusiana, Evi; Suriyani, Suriyani; Ryadinency, Resty
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 2 (2024): Volume 7 No 2 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i2.12763

Abstract

ABSTRAK Kelurahan Bontonompo selatan merupakan salah satu wilayah kerja dari Puskesmas Bontonompo 1. Stunting merupakan salah satu masalah gizi yang dihadapi di puskesmas Bontonompo 1, selain itu Ibu hamil juga perlu untuk diberikan gizi maksimal karena salah satu pencetus stunting adalah karena gizi pada saat hamil yang kurang diperhatikan. Terdapat 14 anak stunting dan 6 Ibu hamil KEK. Data ini diperoleh dari 20 kader posyandu yang tersebar di masing-masing dusun. Puskesmas Bontonompo telah memiliki program untuk penanganan gizi anak stunting yaitu program dapur gizi. Namun kader kesulitan dalam pemanfaat bahan pangan yang tersedia di sekitar serta beberapa program yang belum menyentuh Ibu hamil. Pelaksanaan Pengabdian Masyarakat ini bertujuan untuk memberikan edukasi kepada kader terkait stunting, Ibu hamil KEK serta pemanfaatan daun kelor salah satunya dengan pembuatan BISIKOIK LEKOK KELOROK. Terdapat beberapa metode yang digunakan dalam pelaksanaan pengabdian ini diantaranya observasi berupa pengukuran BB dan TB anak serta Lingkar Lengan Atas (LILA) untuk Ibu hamil, pendidikan kesehatan serta demonstrasi. Observasi awal pengukuran stus gizi anak, diperoleh sebanyak 14 anak yang teridentifikasi stunting serta 6 Ibu hamil KEK, observasi dilaksanakan selama 2 hari. Kemudian dilakukan pendidikan kesehatan kepada seluruh kader dan dilanjutkan dengan demonstrasi pembuatan biskuit yang berbahan dasar daun kelor. Pendampingan dan distribusi bikcuit dilaksanakan oleh kader. Kegiatan pengabdian memberi dampak pada pengetahuan kader serta berdampak pula pada peningkatan status gizi balita stunting dan Ibu hamil KEK. Biskuit daun kelor ini menjadi salah satu menu yang diberikan pada kegiatan posyandu balita dan Ibu hamil, serta menu selingan pada program Pemberian Makanan Tambahan yang telah berjalan di Desa Tanrara yang terlaksana setiap 1 (satu) kali dalam seminggu Kata Kunci: Biskuit Daun Kelor, Ibu Hamil KEK, Stunting, Kader Pelatihan  ABSTRACT South Bontonompo Village is one of the working areas of the Bontonompo Health Center. Stunting is one of the nutritional problems faced at the Bontonompo Health Center, besides that pregnant women also need to be given maximum nutrition because one of the triggers of stunting is due to nutrition during pregnancy that is not considered. There were 14 stunted children and 6 pregnant women with SEZ. This data was obtained from 20 posyandu cadres spread across each hamlet. Puskesmas Bontonompo has a program for handling the nutrition of stunted children, namely the nutrition kitchen program. However, cadres have difficulty in utilizing the food available around them and some programs have not touched pregnant women. The implementation of this Community Service aims to provide education to cadres related to stunting, pregnant women with SEVERITY and the utilization of moringa leaves, one of which is by making BISIKOIK LEKOK KELOROK. There are several methods used in the implementation of this service including observation in the form of measuring children's weight and TB and Upper Arm Circumference (LILA) for pregnant women, health education and demonstrations. Initial observations of measuring the nutritional status of children, obtained as many as 14 children who were identified as stunted and 6 pregnant women with SEZ, observations were carried out for 2 days. Health education was then provided to all cadres and continued with a demonstration of making biscuits made from moringa leaves. Assistance and distribution of biscuits were carried out by cadres. Moringa leaf biscuits are one of the menus that can be given at posyandu activities for toddlers and pregnant women, as well as a side menu in the Supplementary Feeding program that has been running in Tanrara Village which is carried out once a week. Keywords: Moringa Leaf Biscuits, Pregnant Women With SEZ, Stunting, Cadres Training
Pendampingan santri dalam pemanfaatan tanaman obat untuk mencegah anemia Lusiana, Evi; Saleh, Muhammad Irsan; Tamzil, Nia Savitri; Oktariana, Desi; Sabrina, Tia; Turridho, Aisya; Qonitah, Zahrah Aliyah
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 3 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6l3.178

Abstract

Anemia is a condition characterized by a deficiency of hemoglobin in the blood, which can impair productivity and health, particularly among vulnerable populations such as Islamic boarding school students (santri). Education and the utilization of herbal plants have potential as effective measures for anemia prevention. However, these approaches are underutilized in this population. This study aimed to enhance the knowledge and skills of santri regarding anemia prevention, the use of herbal plants, and health screening at the Modern Thawalib Sriwijaya Islamic Boarding School in Palembang, involving 40 participants (67.5% male, 32.5% female). Activities included educational sessions, health screenings, and guidance on herbal plant cultivation. Evaluations were conducted using pretest and posttest assessments. Results demonstrated significant improvements in knowledge (from 30% to 95%), attitudes (from 15% to 65%), and practices (from 47.5% to 82.5%). Hemoglobin screening revealed moderate anemia in 42.5% of participants, mild and severe anemia in 10% each, and no anemia in 37.5% of participants. Educational interventions effectively improved the understanding, attitudes, and behaviors of santri concerning anemia and the preventive potential of herbal plants.
EFEKTIFITAS KEGIATAN EMPOWERMENT EDUCATION DALAM MENINGKATKAN SELF EFFICACY PASIEN KANKER PAYUDARA DI RS.UMUM KOTA MAKASSAR Lusiana, Evi; Malik, Muh. Zukri; Suriyani, Suriyani
Journal of Islamic Nursing Vol 5 No 2 (2020): Journal Of Islamic Nursing
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/join.v5i2.17667

Abstract

Breast cancer is a problem that often occurs in women both in developed and developing countries. For this reason, it is necessary to prevent the increasing mortality rate, one of which is by increasing self-efficacy which can be achieved by providing advice, information and motivation with empowerment education. Based on this, the researchers conducted this study with the aim of knowing the effect of empowerment education in increasing the self-efficacy of breast cancer patients. The research method used is a quantitative study with a one group test approach. The results obtained are from 5 (five) items of self-efficacy, 3 (three) items that have changed, namely self-confidence in getting information about illness / complaints experienced (p: 0.023), receiving help from the community, family and friends (p. : 0.02), and treats breast cancer disease and symptoms (0.041). Based on these results it can be concluded that empowerment education activities should be one of the activities of providing nursing interventions to breast cancer patients.Keywords: Empowerment Education; Self Efficacy; Breast cancer
PURPLE SWEET POTATO EXTRACT ATTENUATES GENTAMICIN-INDUCED HEPATOTOXICITY IN WISTAR RATS Evi Lusiana; Theodorus; Khairunnisa Rizqika Amanda Putri
International Archives of Medical Sciences and Public Health Vol. 7 No. 1 (2026): International Archives of Medical Sciences and Public Health
Publisher : Pena Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53806/iamsph.v7i1.1474

Abstract

Purple sweet potato extract (Ipomoea batatas L.) has hepatoprotective potential due to its antioxidant properties. This study evaluated the effect of purple sweet potato extract (PSPE) on gentamicin-induced hepatotoxicity in male Wistar rats. Thirty rats were divided into five groups: negative control, positive control, and PSPE-treated groups receiving 50, 100, and 200 mg/kg body weight (BW). Hepatotoxicity was induced using gentamicin for seven days, followed by extract administration for fourteen days. Caspase-3 expression was analyzed using immunohistochemistry, while fibrosis was assessed using Masson’s Trichrome staining and METAVIR scoring. One-way ANOVA showed significant differences in Caspase-3 expression among groups (p ¡ 0.001). PSPE was associated with reduced Caspase-3 expression and attenuated hepatic fibrosis, with the strongest effect observed at 200 mg/kgBW. Histopathological evaluation showed predominantly METAVIR grade F0 fibrosis at doses of 100 and 200 mg/kgBW. These findings suggest potential hepatoprotective effects of PSPE in this preclinical model of gentamicin-inducedhepatotoxicity.
Co-Authors Abda Arif Aisyah Fristania Ditamor Amanda Putri, Khairunnisa Rizqika Amira Azra Arisa Putri Andriani, R.A. Linda Ardesy Melizah Kurniati Aseptianova Aseptianova Ayeshah A Rosdah Az Zahra, Zaviera Azizah, Aida Nur Banun, Syahri Debby Handayati Harahap Debby Handayati Harahap Debby Handayati Harahap Debby Handayati Harahap Desi Oktariana Desi Oktariana Desi Oktariana Eny Rahmawati, Eny Ernawati Sinaga Eskalatin, Khaira Farida Fatmawati, Fatmawati Fifa Argentina Fifa Argentina Fifa Argentina Gita angrini Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Hafizzanovian, Hafizzanovian Indri Seta Septadina Islami, Arya Putera Ismail, Hidayati Julianus Ake Kemas Ya’kub Rahadiyanto Kessyy Widowati Khairunnisa Rizqika Amanda Putri Komar, Muhammad Hafidh Legiran Legiran Lorenza, Geofanny Luthfiah, Qonita M. T. Kamaluddin Manawan, Efman E.U. Maria Sidabutar, Carolina Mgs. Irsan Saleh, Mgs. Irsan Mikawati Mikawati, Mikawati Muaningsih Muaningsih, Muaningsih Muh. Zukri Malik Muhammad Irsan Saleh Muhammad Reagan Muhammad, Fadhil Nafrah Ardita Nashif, Arkan Abdullah Nia Savitri Tamzil Nia Savitri Tamzil Nita Parisa Nita Parisa Nita Parisa Oktariana, Desi pariyana, Pariyana Phey Liana Phey Liana Pratiwi, Rizky Qonitah, Zahrah Aliyah Rahadiyanto, Kemas Ya’kub Rahardiyanto, Kemas Ya’kub RATNA SARI Resty Ryadinency Ricardo Simanjuntak Rivani, Erizka Rizky Pratiwi Rofflin, Eddy Rosdah, Ayesha Augusta Sabrina, Tia Saleh, M. Irsan Saleh, Muhammad Irsan Sindy Bintang Permata Smaradhna, Safira Sudarto Sudarto Suriyani Suriyani, Suriyani Sutandar, Vivi Hendra Syarinta Adenina Theodorus Theodorus Theodorus Theodorus Theodorus Turridho, Aisya Veny Larasati Wicaksono, Bonanza Abi Wildan Dwi Putra Widodo Zanaria, Rima Zen Hafy