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All Journal International Journal of Public Health Science (IJPHS) ILMU KELAUTAN: Indonesian Journal of Marine Sciences Jurnal Presipitasi : Media Komunikasi dan Pengembangan Teknik Lingkungan Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Lingkungan Media Kesehatan Masyarakat Indonesia JURNAL TEKNOLOGI LINGKUNGAN Disease Prevention and Public Health Journal Jurnal Kesehatan Lingkungan Journal of Industrial Hygiene and Occupational Health (JIHOH) Public Health of Indonesia MAJALAH ILMIAH GLOBE Jambura Journal of Health Sciences and Research Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Bioscientia Medicina : Journal of Biomedicine and Translational Research Poltekita : Jurnal Ilmu Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Riset Jakarta Jurnal Promotif Preventif Jurnal Cahaya Mandalika Bioscientia Medicina : Journal of Biomedicine and Translational Research Media Publikasi Promosi Kesehatan Indonesia (MPPKI) JOURNAL OF WETLANDS ENVIRONMENTAL MANAGEMENT LEMBARAN PUBLIKASI MINYAK DAN GAS BUMI Unnes Journal of Public Health Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Haryoto Kusnoputranto
Universitas Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Earth & Planetary Sciences Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Aminolevulinic Acid Dehydratase Allelic Frequency and Lead Toxicity in Children Under-Five in a Former Used Lead-Acid Battery Area Irawati, Yana; Kusnoputranto, Haryoto; Achmadi, Umar Fahmi; Safrudin, Ahmad; Sitorus, Alfred; Risandi, Rifqi; Wangsamuda, Suradi; Permana, Dendi Hadi; Syahrani, Lepa; Dewayanti, Farahana Kresno; Asih, Puji B S; Syafruddin, Din
Kesmas Vol. 17, No. 1
Publisher : UI Scholars Hub

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Abstract

Polymorphisms in the Aminolevulinic Acid Dehydratase (ALAD) gene responsible for the ALAD1 and ALAD2 alleles have been implicated in susceptibility to lead toxicity. This study aimed to determine the allelic frequency of ALAD2 among children living in Bogor District, Indonesia, and its association with blood lead levels (BLLs) and lead toxicity. A cross-sectional study involving 128 children was conducted during September-October 2019 in the former ULAB area in Cinangka Village. The ALAD polymorphism, BLLs, and hematological parameters were evaluated. Blood samples were taken for dried blood spotting on filter paper, blood film, and BLL measurement. The PCR amplification and sequencing of the genomic DNA revealed the presence of two forms of the ALAD2 allele: 177C and 177T with a frequency of 0.05. Analysis of the correlation between the ALAD2 allele, BLLs, and basophilic stippling revealed that ALAD2 carriers had a five times higher risk of high BLLs, (OR = 5.359, p-value = 0.155) and had a slightly higher risk of exhibiting basophilic stippling (OR = 1.09, p-value = 1.000). Although not statistically significant, these findings suggested that the ALAD genotype may modify BLLs and lead to toxicity. The ALAD2 allele(177T) is firstly reported in any population in the world.
Ambient Particulate Matter with Blood Pressure in Adult Women Living in Urban City Aliyyah, Nurusysyarifah; Kusnoputranto, Haryoto; Wispriyono, Bambang; Fitria, Laila
Kesmas Vol. 19, No. 5
Publisher : UI Scholars Hub

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Abstract

Ambient air pollution, especially from fine particles, contributes to human mortality from cardiovascular and respiratory diseases, for which high blood pressure (BP) is a major modifiable risk factor. This study aimed to analyze the influence of ambient particulate matter (PM2.5) on the risk of high BP leading to hypertension. This study used a cross-sectional design on 118 adult women living in Central Jakarta, Indonesia. Participants were selected from a 1-km radius of the nearest air quality monitoring station with available data PM2.5. Linear regression was analyzed to examine the relationship between PM2.5 and systolic and diastolic BPs adjusted for potential confounders. The annual means of PM2.5 concentration was 36±5.74 μg/m3. The linear regression model showed that PM2.5 exposure was associated with systolic BP after controlling with age and body mass index (r = 0.408; R2 = 0.167). The second model showed that exposure to PM2.5 concentration could explain about 10.9% variation of diastolic BP after controlling with age, length of stay, body mass index, smoking status, and diabetes mellitus record. Ambient air PM2.5 has a risk of BP and hypertension among adult women in Central Jakarta.
Environmental Health Risk Assessment of Consumption of Foodstuffs Containing Organophosphate Residues among Farmers Imelda Gernauli Purba, Imelda; Kusnoputranto, Haryoto; Wulandari, Ririn Arminsih; Hartono, Budi
Unnes Journal of Public Health Vol. 14 No. 1 (2025)
Publisher : Universitas Negeri Semarang (UNNES) in cooperation with the Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v14i1.5929

Abstract

The use of pesticides in the agricultural sector results in contamination of foodstuffs by pesticide residues, thus becoming a source of exposure to the body and resulting in health problems. The purpose of this study was to analyse the health risks due to the consumption of foodstuffs containing organophosphate residues in farmers. The design of this study was cross-sectional, employing the Environmental Health Risk Assessment (EHRA). The study population was farmers in the North Dempo District of Pagar Alam. A total of 117 farmers were sampled randomly. Environmental samples consisted of five red chilies and five tomatoes, which were selected purposively. Organophosphate residues were quantified using liquid Chromatography Tandem Mass Spectrometry. Body weight was measured using calibrated body scales. Activity pattern data were collected through interviews using a questionnaire. Data analysis was conducted using the  EHRA formulas. The results demonstrated the presence of Chlorpyriphos in red chillies  at a concentration of 3,05 mg/kg, while Profenofos was found at 0.0731 mg/kg and 0.0118 mg/kg.  The presence of Chlorpyriphos in tomatoes samples at a concentration of 0.4439 mg/kg, while Profenofos was found at 0.0112 mg/kg and 0.2043 mg/kg. The risk quotient  for consumption of red chillies containing Chlorpyriphos was found to be 0.0447, while that for Profenofos was 0.2476. The risk quotient for consumption of tomatoes containing Chlorpyriphos was found to be 0.0302, while that for Profenofos was 2.92. It can be concluded that respondents were at non-carcinogenic health risk due to consumption of tomatoes containing Profenofos.
Pengelolaan Limbah Bahan Berbahaya dan Beracun (B3) Elektronik (E-Waste) dan Tingkat Kesadaran Masyarakat dalam Mengelola Limbah di Wilayah Daerah Khusus Jakarta Tarigan, Bayu Pratama; Kusnoputranto, Haryoto
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 3 No. 3 (2022)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v3i3.3318

Abstract

Latar belakang: Limbah elektronik (e-waste) merupakan salah satu limbah Bahan Berbahaya dan Beracun (B3) yang terus mengalami peningkatan jumlah setiap tahunnya. Provinsi Daerah Khusus Jakarta merupakan provinsi dengan data timbulan sampah tertinggi di Indonesia dengan timbulan tertinggi berada di Kota Administrasi Jakarta Timur sebesar 844.252,43 ton per tahun. Tujuan dari penelitian ini adalah menganalisis kegiatan pengelolaan limbah elektronik (e-waste) berdasarkan aspek manajemen pengelolaan limbah B3 serta menganalisis tingkat kesadaran masyarakat dalam mengelola limbah elektronik (e-waste) di wilayah Daerah Khusus Jakarta. Metode: Penelitian ini menggunakan metode kombinasi dengan desain mix method. Hasil: Analisis mengenai tingkat kesadaran masyarakat dalam mengelola limbah elektronik di tingkat rumah tangga Provinsi DKI Jakarta didapatkan hasil bahwa tingkat kesadaran tertinggi masyarakat di wilayah DKI Jakarta berada pada wilayah Kota Administrasi Jakarta Utara dengan persentase sebesar 82,95%, sedangkan tingkat kesadaran masyarakat terendah berada pada wilayah Kota Administrasi Jakarta Pusat dengan persentase sebesar 76%. Kesimpulan: Berdasarkan aspek manajemen pengelolaan limbah elektronik yang berlaku di wilayah Daerah Khusus Jakarta, pengelolaan limbah elektronik sudah cukup baik. Pemerintah mampu menginisiasi program tersebut dimana daerah lain belum ada yang mencanangkan program pengelolaan limbah elektronik tersebut. Saran: Perlu adanya upaya pengkategorian lebih lanjut terhadap limbah elektronik yang dikumpulkan agar pada saat proses pemisahan dapat terurai dengan lebih sistematis.
Co-Authors Agrayanto, Bagus Ferry Agustini Agustini Agustini, Agustini Ahmad Safrudin Aliyyah, Nurusysyarifah Apriliya Adha Aria Kusuma Asih, Puji B S Bagus Ferry Agrayanto Bambang Wispriyono Budi Hartono Budi Hartono Budiawan Budiawan Budiawan Budiawan Dewayanti, Farahana Kresno Din Syafruddin Djarot S Wisnubroto Djoko M Hartono Djoko M. Hartono Dwiyitno Dwiyitno Eko Handoyo Ela Laelasari Ema Hermawati Ezra Ganesha Prihardanu Febriyana Mustika Dewi S Gilang Anugerah Munggaran H.M.H. Bintoro Djoefrie H.M.H. Bintoro Djoefrie, H.M.H. Bintoro Halik Hadi Hayati Sari Hasibuan Herdis Herdiansyah Hery Unita Versitaria Hisyam Musthafa, Hisyam I Made Djaja Imelda Gernauli Purba, Imelda Imelda Gernauli Purba, Imelda Gernauli Imelda Masni Juniaty Sianipar Ira Ayu Hastiaty Ira Ayu Hastiaty Irawati, Yana Isnatami Nurul Azni, Isnatami Nurul Ita Junita Januar Ariyanto Jatna Supriatna Kario, Asrit Jessica Laila Fitria Marulak Bonaparte Manurung Misri Gozan Murdahayu Makmur Murdahayu Makmur Nova Amalia Sakina Ony Rosalia Oscar leonard Manaloe Permana, Dendi Hadi Pradnya Rahmani Prasetyadi, Prasetyadi Prima Gita Pradapaningrum Primanti, Afthina Puri Wulandari, Puri Rachmadhi Purwana Ratna Maya Paramita Risandi, Rifqi Rizal Syarief Saptarining Wulan Saptarining Wulan, Saptarining Sembiring, Eva Kasih Setyo Moersidik Setyo S Moersidik Sitorus, Alfred Sodri, Ahyahudin Surya Kusuma Purba Suryawan, I Wayan Koko Suyud Warno Utomo Suyud Warno Utomo Suyud Warno Utomo Syahrani, Lepa Tarigan, Bayu Pratama Tri Edhi Budhi Soesilo Umar Fahmi Achmadi Umar Fahmi Achmadi Wangsamuda, Suradi Wardani, Laras Andria Wulandari, Puri Wulandari, Ririn Arminsih Zakianis Zakianis