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All Journal ODONTO Dental Journal Majalah Obat Tradisional Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JCPS (Journal of Current Pharmaceutical Sciences) Dentin Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Odonto dental journal Jurnal Pengabdian Masyarakat Panacea Jurnal Sains dan Kesehatan Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Yusrinie Wasiaturrahmah
Universitas Lambung Mangkurat
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN KALANGKALA (Litsea angulata) TERHADAP PERTUMBUHAN BAKTERI Porphyromonas gingivalis (In vitro) Nor Rahman Sugiarto; Yusrinie Wasiaturrahmah; Tri Nurrahman; Muhammad Yanuar Ichrom Nahzi; Juliyatin Putri Utami; Bayu Indra Sukmana
Dentin Vol 9, No 2 (2025)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v9i2.17742

Abstract

ABSTRACTBackground: Dental and oral health has not been a major focus due to the low level of public awareness regarding the importance of maintaining dental and oral health in Indonesia. Periodontitis is a disease with a prevalence of 74.1% in Indonesia. The main cause of chronic periodontitis is the bacterium  Porphyromonas gingivalis. Chlorhexidin  0.2% is gold standard that preventing periodontitis. However Chlorhexidin  0.2% has long-term side effects such as tooth discolouration. Therefore, an alternative mouthwash that has antibacterial properties is needed. Kalangkala leaf (Litsea angulata) is known to have the potential to inhibit the growth of  Porphyromonas gingivalis bacteria. Objective: To determine the antibacterial effectiveness of kalangkala (Litsea angulata) leaf extract against  Porphyromonas gingivalis bacteria with concentrations of 6.25%, 12.5%, 25%, and 50% based on the minimum inhibitory Concentration (MIC) and minimum bactericidal Concentration(MBC). Methods: True experimental research with posttest-only with control group design. The sample consisted of 6 groups with Chlorhexidin 0.2% as positive control and distilled water as negative control with 4 samples each. Data were analysed using normality, homogeneity, Krusskall wallis, and Mann-whitney tests. Results: From the test results, there was no minimum inhibition 6.25%, 12.5%, 25%, and 50%. The testing was not pursued for MBC. Conclusion: There is no antibacterial effectiveness of kalangkala (Litsea angulata) leaf extract against Porphyromonas gingivalis.Keywords: antibacteria, leaf extract, litsea angulata,  porphyromonas gingivalis ABSTRAK Latar Belakang: Kesehatan gigi dan mulut belum menjadi fokus utama karena tingkat kesadaran masyarakat yang rendah terkait pentingnya merawat kesehatan gigi dan mulut di Indonesia Periodontitis merupakan penyakit dengan prevalensi 74,1% di Indonesia. Penyebab utama periodontitis kronis yaitu bakteri Porphyromonas gingivalis. Chlorhexidin 0,2% merupakan gold standard dalam mencegah terjadinya periodontitis, tetapi Chlorhexidin  0,2% memiliki efek samping jangka panjang seperti perubahan warna pada gigi. Untuk mencegah terjadinya efek jangka panjang tersebut perlu obat kumur alternatif yang memiliki sifat antibakteri. Daun kalangkala (Litsea angulata) diketahui memiliki potensi untuk menghambat pertumbuhan bakteri Porphyromonas gingivalis. Tujuan: Mengetahui efektivitas antibakteri ekstrak daun kalangkala (Litsea angulata) terhadap bakteri Porphyromonas gingivalis dengan konsentrasi 6,25%, 12,5%, 25%, dan 50% berdasarkan Kadar hambat minimum (KHM) dan kadar bunuh minimum (KBM) Metode: Penelitian eksperimen murni (True Experimental) dengan rancangan percobaan menggunakan posttest-only with control group design. Sampel terdiri dari 6 kelompok dengan Chlorhexidin 0,2% sebagai kontrol positif dan akuades sebagai kontrol negatif dengan pengulangan masing-masing sebanyak 4 sampel. Data dianalisis dengan uji normalitas, homogenitas, Krusskall wallis, dan uji Mann-whitney. Hasil: Hasil uji tidak terdapat KHM pada semua konsentrasi ekstrak kalangkala yaitu konsentrasi 6,25%, 12,5%, 25%, dan 50%, sehingga tidak dilanjutkan untuk pengujian KBM. Kesimpulan: Tidak terdapat efektifitas antibakteri ekstrak daun kalangkala (Litsea angulata) konsentrasi 6,25%, 12,5%, 25%, dan 50% terhadap bakteri Porphyromonas gingivalis.Kata Kunci: antibakteri, ekstrak daun, litsea angulata porphyromonas gingivalis
PENGARUH PERENDAMAN GIGI DESIDUI PADA LARUTAN KITOSAN SISIK IKAN HARUAN (Channa striata) TERHADAP PELEPASAN ION KALSIUM Noval Ihza Maulana; Didit Aspriyanto; Deby Kania Tri Putri; Yusrinie Wasiaturrahmah; Sherli Diana
Dentin Vol 8, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/dentin.v8i2.13109

Abstract

ABSTRACTBackground: Haruan fish (Channa striata) scale chitosan solution can maintain tooth structure by reducing the solubility rate of hydroxyapatite which makes up tooth enamel. Haruan fish (Channa striata) scale chitosan solution prevents tooth demineralization in an acidic environment. Objective: To analyze the effect of soaking deciduous teeth in chitosan solution from haruan fish scales (Channa striata) with concentrations of 1.25%, 2.5% and 5% on the release of calcium ions in an acidic environment. Method: Pure experimental research with a post-test only design with control group, consisting of 4 treatment groups. The negative control was immersion of deciduous teeth in lactic acid solution pH 5.2, and treatment groups with concentrations of 1.25%, 2.5% and 5%. All groups soaked deciduous teeth in lactic acid solution with a pH of 5.2 for each group. Measurement of calcium release levels in deciduous teeth using UV-Vis spectrophotometry instruments. Results: The results of this study are hypothesized to be acceptable or that there is an effect of soaking deciduous teeth in haruan fish scale chitosan (Channa striata) concentrations of 1.25%, 2.5% and 5% in inhibiting the release of calcium ions. This study showed that there were no significant differences between the 1.25%, 2.5% and 5% treatment groups, but there were significant differences between the control group and all treatment groups. Conclusion: Haruan fish (Channa striata) scale chitosan with concentrations of 1.25%, 2.5%, and 5% is able to inhibit the release of calcium in deciduous teeth and has potential as a demineralization inhibitor biomaterial.Keywords :  Caries, Calcium, Chitosan, Demineralization, Haruan.  ABSTRAK Latar Belakang: Larutan kitosan sisik ikan haruan (Channa striata) dapat menjaga struktur gigi melalui proses penurunan laju kelarutan hidroksiapatit penyusun enamel gigi. Larutan kitosan sisik ikan haruan (Channa striata) mencegah demineralisasi gigi dalam lingkungan asam. Tujuan: Menganalisis pengaruh perendaman gigi desidui pada larutan kitosan dari sisik ikan haruan (Channa striata) dengan konsentrasi 1,25%, 2,5%, dan 5% terhadap pelepasan ion kalsium dalam lingkungan asam. Metode: Penelitian eksperimental murni dengan desain post-test only with control group, terdiri dari 4 kelompok perlakuan. Kontrol negatif yaitu perendaman gigi desidui pada larutan asam laktat pH 5,2, dan kelompok perlakuan konsentrasi 1,25%, 2,5%, serta 5%. Semua kelompok perendaman gigi desidui dalam larutan asam laktat dengan pH 5,2 dilakukan pada setiap kelompok. Pengukuran kadar pelepasan kalsium gigi desidui menggunakan instrumen spektrofotometri UV-Vis. Hasil: Hasil penelitian ini hipotesis dapat diterima atau adanya pengaruh perendaman gigi desidui pada kitosan sisik ikan haruan (Channa striata) konsentrasi 1,25%, 2,5%, dan 5% dalam menghambat pelepasan ion kalsium. Pada penelitian ini menunjukkan tidak adanya perbedaan signifikan antar kelompok perlakuan 1,25%, 2,5%, dan 5%, namun terdapat perbedaan bermakna antara kelompok kontrol dengan semua kelompok perlakuan. Kesimpulan: Kitosan sisik ikan haruan (Channa striata) dengan konsentrasi 1,25%, 2,5%, dan 5% mampu menghambat pelepasan kalsium pada gigi desidui dan memiliki potensi sebagai biomaterial agen penghambat demineralisasi. Kata kunci : Demineralisasi, Haruan, Kalsium, Karies, Kitosan
ANTIBACTERIAL EFFECTIVENESS OF KECAPI SENTUL EXTRACT (SANDORICUM KOETJAPE MERR.) AGAINST STREPTOCOCCUS MUTANS Pambudi, Adhimas Rilo; Wasiaturrahmah, Yusrinie; Aspriyanto, Didit
Odonto : Dental Journal Vol 8, No 2 (2021): December 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.864 KB) | DOI: 10.30659/odj.8.2.1-10

Abstract

ABSTRACTBackground: One of the causing dental caries is a microorganism, namely Streptococcus mutans. Kecapi sentul leaves extract (Sandoricum koetjape Merr.) contain alkaloid, flavonoid, saponin, steroid, phenol, and triterpenoid which have antibacterial properties on the inhibition Streptococcus mutans which has the potential to prevent dental caries.Method: This research uses a laboratory experimental design with a post-test control group only design, using seven treatment groups, namely kecapi sentul leaves extract with the concentration of group 30%, 40%, 50%, 60%, 70%, Chlorhexidine gluconate 0.2% as positive control and aquadest as negative control were repeated 4 times. Result: Non parametric test Kruskal Wallis and Post Hoc Mann Whitney methods showed that each treatment group was significantly different in the diameter of the formed inhibition zone. The mean diameter of the inhibition zone with a concentration of 30% was 9.1 mm, 40% was 13.3 mm, 50% was 17.13 mm, 60% was 18.65 mm and 70% was 21.05 mm.Conclusion: Kecapi sentul leaves extract (Sandoricum koetjape Merr.) with the concentration of group 30%, 40%, 50%, 60% and 70% have antibacterial potential against the growth of Streptococcus mutans.
Co-Authors Adhimas Rilo Pambudi Adhiya, Geyanina Melda Agung Satria Wardhana Alexander Sitepu Almadina Latanza Amy Nindia Carabelly Anna Khumaira Sari Arifin, Rahmad Asphia Rahmah Aspriyanto, Didit Bambang Setiawan Bayu Indra Sukmana Beta Widya Oktiani Cita Nursyaina Tasya Dewi Nurdiana Dewi Puspitasari Dewi Puspitasari Diana Wibowo Difa Intannia Dini Maulani Erida Wydiamala Firdaus, I Wayan Arya Krishnawan Fitri Syahrina Fransiska Uli Arta Puspitasari I Wayan Arya Krishnawan Firdaus I Wayan Arya Krisnawan Firdaus Ichrom Nahzi, Muhammad Yanuar Isnaini, Nazhifah Jatmiko, Habibi Naufal Khoirunnisa Muslimawati Kholish Atikah Azzam Krisna Erlangga Putra Ramadhani Laili Nurul Islami Luthfi Ridhwana Maharani Laillyza Apriasari Maharani Laylliza Apriasari Maman Diki Wahyudi Mega Sari Mia Fitriana MUHAMMAD RAYHAN Nahdha Nahdha Nahdha Nahdiya Rahmah Nahdiya Rahmah Nahdiya Rahmah Nahzi, Yanuar Ichrom Namira Aghnina, A.M. Della Namira Fathya Salsabila Nida Amalia Nor Kamalia Nor Rahman Sugiarto Noval Ihza Maulana Nugraha, Tyas Setia Nurrahman, Tri Okta Muthia Sari Okta Muthia Sari Pambudi, Adhimas Rilo Pramitha, Selviana Rizky Putra, Aditya Maulana Perdana Putra, Fedriko Gamaliel Rahmatullah, Satrio Wibowo Ramadhaniyah, Nur Raudhatul Jannah Reski Nurafia Rosihan Adhani, Rosihan Sandi, Dita Ayulia Dwi Sherli Diana Tri Putri, Deby Kania Utami, Juliyatin Putri