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Steroids Produced by Endophytic Fungus Lasiodiplodia Theobromae From Aglaia Argentea Blume and Their Cytotoxic Activity Against Hela Cervical Cancer Cell Lines Supratman, Unang; Purbaya, Sari; Harneti, Desi; Wulandari, Asri Peni; Mulyani, Yeni; Azhari, Azmi; Sari, Aprilia Permata
Molekul Vol 18 No 3 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.3.7824

Abstract

Three steroids, ergosterol (1), ergosterol peroxide (2) and stigmasterol (3) have been isolated from endophytic fungus, Lasiodiplodia theobromae derived from the root of Aglaia argentea Blume. The steroids were isolated by vacuum chromatography and column chromatography, the chemical structure was established following the analysis of 1D-NMR, 2D-NMR, IR, MS and by comparison with previously reported spectra data. Ergosterol peroxide (2) and stigmasterol (3) were reported for the first time isolated from Lasiodiplodia theobromae endophytic fungus. Cytotoxic activities of the compounds were tested with resazurin assay against HeLa cervical cancer cells, compound 2 displayed strongest cytotoxic activities against HeLa cervical cancer cells with IC50 values of 0.28 µM, while compounds 1 and 3 showed IC50 values of 0.34 µM and 27.32 µM, respectively
EXPLORATION OF THE BIOACTIVE POTENTIAL OF RHIZOPHORACEAE MANGROVE PLANTS: IMPLICATIONS IN THE FIELD OF FISHERIES Mulyani, Yuniar; Mulyani, Yeni; Aisyah, Aisyah
Jurnal Perikanan Unram Vol 15 No 2 (2025): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v15i2.1395

Abstract

Mangrove forests, as coastal ecosystems rich in biodiversity, play an important role in ecology and the fisheries sector. Mangroves not only function as coastal protectors and habitats for aquatic organisms but also produce bioactive compounds that have potential as antibacterial, antioxidant, antifungal, and antiviral agents. Research on mangrove plants from the Rhizophoraceae family, such as Bruguiera, Kandelia, Ceriops, and Rhizophora, has shown that compounds like flavonoids, tannins, alkaloids, and saponins have significant biological activities. Flavonoids act as antimicrobials, while tannins inhibit bacterial growth by precipitating proteins. Alkaloids disrupt bacterial cell walls and have potential in combating cancer cells. Studies also reveal significant antioxidant activity, with some mangrove extracts showing great potential in combating free radicals. Moreover, these compounds offer potential in reducing reliance on synthetic antibiotics for the treatment of cultured fish diseases and provide opportunities for the development of natural-based health products. This review aims to integrate recent findings on the bioactivity of mangrove plants and propose innovative applications of bioactive compounds in fisheries and conservation with a focus on ecosystem sustainability and optimal use of natural resources.
PENJADWALAN DINAS PERAWAT BERHUBUNGAN DENGAN KEPUASAN PASIEN DI RUANG RAWAT INAP RSUD ULIN BANJARMASIN Rahman, Syawalludin; Mulyani, Yeni; Rizany, Ichsan
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 6 No 1 (2018): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.532 KB)

Abstract

Patient satisfaction during hospitalization is still in low category. The low patient satisfaction isinfluenced by several factors, one of which is the scheduling of nurse service. This study wasmade to know the correlation between scheduling of nurse service and patient satisfication levelat RSUD Ulin Banjarmasin hospital. This research used correlation design with cross sectionalapproach and accidental sampling technique. Research respondents amounted to 92 people.December 2017 research period and measuring instruments used in the form of questionnaires.The result of the analysis shows that there is a positive relationship between scheduling of nursesservice that is perceived by patient with patient satisfaction level in ward of RSUD UlinBanjarmasin. (P Value = 0,000 <0.05). Suggestion of this research is expected to head of roomand nurse to cooperate in determining good service scheduling with manager direction for thecreation of optimal service for patient satisfaction.
TERAPI MELUKIS TERHADAP KOGNITIF PASIEN SKIZOFRENIA DI RUMAH SAKIT JIWA SAMBANG LIHUM Norsyehan; Lestari, Dhian Ririn; Mulyani, Yeni
Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan Vol 3 No 2 (2015): Dunia Keperawatan: Jurnal Keperawatan dan Kesehatan
Publisher : School of Nursing, Faculty of Medicine and Health Science, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.589 KB)

Abstract

Painting therapy is a therapy which encourages someone to express and to understand the emotiontrough artistic expressions and creative process to be able to cure cognitive, affective, andpsychomotoric functions. This study was aimed to find the effect of painting therapy on theschizophrenia patients’ cognitive. This study used pre-experiment method with design approach onegroup pre and post design. The respondents involved in this study were 30 patients with accidentalsampling. The data collection was done using cognitive ability measurement before and after thepainting therapy. The experiment analysis used T- test dependent. The result of the study showed thatthere was an effect of painting therapy treatment on the schizophrenia patients’ cognitive at SambangLihum psyichiatric hospital with the significant value of 0.000 which meant p< 0.05. It was suggestedto apply painting therapy on schizophrenia patients to improve their cognitive function.
ESTIMATION OF CARBON STORAGE POTENTIAL IN THE MANGROVE FOREST REHABILITATION AREA IN SEBELE VILLAGE, RIAU ISLANDS Lestari, Indri; Arief, Mochamad Candra Wirawan; Mulyani, Yeni; Ismail, Mochamad Rudyansyah; Widyasthana, Ferdiansyah Naufal
Jurnal Perikanan Unram Vol 15 No 4 (2025): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v15i4.1707

Abstract

Global warming is a phenomenon of increasing the average temperature of the earth's surface. Carbon can be stored in various forms in ecosystems, one of which is the concept of blue carbon. This research aims to analyze the condition of the mangrove ecosystem and the potential for carbon storage in the mangrove forest rehabilitation area in Sebele Village, Karimun Regency, Riau Islands. This research was conducted from October 2024 to July 2025 in the mangrove forest rehabilitation area of Sebele Village, Riau Islands Province. The method used in this research is the survey method. Standing biomass data was obtained using allometric equations. The research results show that the level of tree density in the mangrove forest rehabilitation area of Sebele Village is in the Sparse category. At the tree level, it is dominated by the Xylocarpus granatum species, while at the sapling level it is dominated by the Rhizophora mucronataspecies. The highest carbon storage value is found in the Avicennia marina species with a carbon storage value of 14.44 tons/ha. And the potential carbon storage from the calculation results obtained a carbon storage value of 61.43 tons/ha. The carbon storage value is directly proportional to the standing biomass. The greater the standing biomass, the greater the carbon stored.
MOTIVASI ODHA DALAM MENJALANI PROGRAM PENGOBATAN ANTIRETROVIRAL DI POLIKLINIK VCT RSUD DR. H. MOCH. ANSARI SALEH BANJARMASIN mahdalena, mahdalena; Mulyani, Yeni; Fahrian, Hijrah
JURNAL CITRA KEPERAWATAN Vol 4 No 2 (2016): JURNAL CITRA KEPERAWATAN
Publisher : Poltekkes Kemenkes Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.114 KB) | DOI: 10.31964/jck.v4i2.58

Abstract

Motivasi merupakan salah satu faktor yang berperan penting bagi ODHA dalam menjalani program pengobatan ARV. Jika motivasi ODHA rendah maka berdampak buruk bagi kesehatan ODHA tersebut. Tujuan penelitian ini adalah mengidentifikasi gambaran motivasi ODHA dalam menjalani program pengobatan ARV berdasarkan karakteristik demografi. Jenis penelitian ini menggunakan metode penelitian deskriptif non eksperimen dengan sampel ODHA yang menjalani program pengobatan ARV di RSUD Dr. H. Moch. Ansari saleh Banjarmasin yang berjumlah 47 sampel. Teknik pengambilan sampel menggunakan tekinik Accidental Sampling dan instrument yang digunakan dalam penelitian iniyaitu kuesioner. Dari 47 sampel didapatkan hasil penelitian yang menunjukan sejumlah 42 responden (89.3 %) dalam motivasi tinggi dan 5 responden (10.7 %) dalam motivasi rendah. Bagi pasien yang memiliki tingkat motivasi rendah diharapkan untuk aktif dalam mengikuti program-program yang diperlukan sedangkan bagi pasien yang memiliki tingkat motivasi tinggi diharapkan mampu mempertahankan motivasinya tersebut. Â Â
KEANEKARAGAMAN MAKROZOOBENTOS SEBAGAI INDIKATOR KONDISI PERAIRAN DI EKOSISTEM MANGROVE PULAU PARI, KEPULAUAN SERIBU Bai'un, Nurul Hanifah; Riyantini, Indah; Mulyani, Yeni; Zallesa, Sheila
JFMR (Journal of Fisheries and Marine Research) Vol. 5 No. 2 (2021): JFMR
Publisher : Faculty of Fisheries and Marine Science, Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jfmr.2021.005.02.7

Abstract

Makrozoobentos mempunyai habitat hidup yang relatif tetap, pergerakannya terbatas, dan hidup di dalam maupun di dasar perairan. Sifat tersebut yang menjadikan makrozoobentos baik digunakan sebagai indikator biologis di suatu perairan. Tujuan riset ini adalah untuk mengetahui kelimpahan individu, keanekaragaman jenis, dan dominansi makrozoobentos pada ekosistem mangrove di Pulau Pari, mengetahui kondisi fisik dan kimia perairan ekosistem mangrove Pulau Pari dan menganalisis keanekaragaman makrozoobentos sebagai indikator kondisi perairan di ekosistem mangrove Pulau Pari. Riset ini dilaksanakan pada bulan Oktober 2020 di Pulau Pari, Kepulauan Seribu. Lokasi pengambilan data dibagi menjadi 4 stasiun dengan karakteristik yang berbeda-beda. Metode yang digunakan adalah metode purposive sampling yang dilakukan di 4 stasiun berbeda dengan 3 plot disetiap stasiunnya. Hasil riset menunjukkan bahwa terdapat 15 spesies terdiri dari 3 filum dan 4 kelas yang tersebar dalam 4 stasiun. Nilai kelimpahan makrozoobentos pada ekosistem mangrove di Pulau Pari berada pada nilai 22 – 71 ind/m2. Nilai indeks keanekaragaman makrozoobentos pada ekosistem mangrove di Pulau Pari berada pada nilai 2,1 – 5,67 dengan kategori sedang sampai tinggi. Nilai indeks dominansi makrozoobentos pada ekosistem mangrove di Pulau Pari berada pada nilai 0,15 – 0,84 dengan kategori rendah sampai tinggi. Kualitas perairan ekosistem mangrove di Pulau Pari yang meliputi suhu, pH, DO, dan salinitas menunjukkan kualitas yang baik dan mampu untuk mendukung kehidupan makrozoobentos. Hasil analisa hubungan parameter perairan dengan keanekaragaman makrozoobentos menunjukkan bahwa pH memiliki korelasi sangat kuat negatif, suhu memiliki korelasi kuat negatif, DO memiliki korelasi sedang positif, dan salinitas memiliki korelasi sedang negatif.
ANALISIS STATUS KEBERLANJUTAN EKOWISATA MANGROVE MUNDU, DESA MUNDU PESISIR, KECAMATAN MUNDU, KABUPATEN CIREBON Ardhiansyah, Rasendriya Naufal; Prihadi, Donny Juliandri; Mulyani, Yeni; Pamungkas, Wahyuniar; Saptari, Muhammad Khairan; Zendina, Luthfia
Jurnal Perikanan Unram Vol 15 No 5 (2025): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v15i5.1866

Abstract

Mundu Mangrove Ecotourism is located in Mundu Pesisir Village, Mundu District, Cirebon Regency. Ecotourism is a form of tourism that is managed through a conservation approach. This study aims to analyze the sustainability status of mangrove ecotourism based on five dimensions of ecology, economy, socio-culture, infrastructure, and institutional law using the RAPFISH approach, identify critical attributes that affect sustainability, and formulate mangrove ecotourism development strategies in Mundu Pesisir Village. Data were collected through field surveys, interviews, and questionnaires to various stakeholders, then analyzed using the Multidimensional Scaling (MDS) method through RAPFISH (Rapid Appraisal Technique for Evaluating Fisheries Sustainability). The results of the sustainability analysis based on 5 dimensions, namely the ecological dimension of 48.33 (less sustainable), the economic dimension of 22.05 (unsustainable), the socio-cultural dimension of 53.13 (moderately sustainable), the infrastructure dimension of 32.14 (less sustainable), and the institutional legal dimension of 76.03 (sustainable). The results of the analysis show that there are still many things that need attention to improve the sustainability score, especially in dimensions that still get a small score.
Fasilitasi PTK PAUD: Pendampingan Pembelajaran Pendidikan di Abad 21 Mutaqin, Moh Fikri Tanzil; Solihat, Anisa; Nuraini, Eviatun; Rohyati, Rohyati; Madaniah AS, Ida; Sumarni, Nini; Liawati, Liawati; Sulehah, Sulehah; Julaehah, Julaehah; Jannah, Rodiatul; Khotimah, Husnul; Alfiah, Alfiah; Mulyani, Yeni
Journal Of Human And Education (JAHE) Vol. 4 No. 3 (2024): Journal of Human And Education
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jh.v4i3.697

Abstract

Pendidikan anak usia dini (PAUD) di abad ke-21 memerlukan pendekatan yang relevan dengan tuntutan zaman. Dalam konteks globalisasi dan perkembangan teknologi, pendidik PAUD harus mampu mengintegrasikan teknologi dalam pembelajaran, memahami keberagaman budaya dan sosial anak, serta memperhatikan perkembangan psikologis anak yang semakin kompleks. Pendampingan pembelajaran menjadi salah satu pendekatan yang relevan dalam mengatasi tantangan tersebut. Melalui pendampingan pembelajaran, pendidik PAUD dapat memperoleh pemahaman yang lebih baik tentang kebutuhan individual anak, meningkatkan kualitas interaksi dengan anak-anak, serta memperluas repertoar strategi pembelajaran yang sesuai dengan perkembangan anak di abad ke-21. Dalam rangka meningkatkan kualitas pendidikan PAUD di abad ke-21. Program ini bertujuan untuk memberikan pendidikan dan pelatihan kepada pendidik PAUD tentang pendampingan pembelajaran yang relevan dengan tuntutan zaman. Bahwa melalui program ini, pendidik PAUD mampu memberikan pendidikan yang lebih relevan dan berkualitas kepada anak-anak, sehingga mereka dapat tumbuh dan berkembang dengan baik di abad ke-21. Dengan demikian, kami berharap dapat memberikan kontribusi yang positif bagi pendidikan anak usia dini di Indonesia
The Display Behavior of Sub-Adult Greater Bird-of-Paradise (Paradisaea apoda): A Learning Process from an Adult? Pramunandya, Raka Aditya; Mardiastuti, Ani; Mulyani, Yeni; Chandra, Vinoba
Jurnal Pengelolaan Sumberdaya Alam dan Lingkungan (Journal of Natural Resources and Environmental Management) Vol 14 No 3 (2024): Jurnal Pengelolaan Sumberdaya Alam dan Lingkungan (JPSL)
Publisher : Pusat Penelitian Lingkungan Hidup, IPB (PPLH-IPB) dan Program Studi Pengelolaan Sumberdaya Alam dan Lingkungan, IPB (PS. PSL, SPs. IPB)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jpsl.14.3.505

Abstract

The Greater Bird-of-Paradise (Paradisaea apoda) is a bird that performs a courtship display (lekking) to attract females during the mating season. The objective of this study was to examine the display behavior of adult and sub-adult males on lek trees as a learning process by a sub-adult and identify the lek trees. The research was conducted in the Tunas Timber Lestari Ltd. Production Forest in central mainland Papua, in a non-breeding season. After a lek tree was found, a video recording was conducted. Analysis was performed from the video. The lek tree was an emergent species with a dense canopy. An adult male was observed to perform a dance display in front of sub-adult males, even in the absence of females. When adult males performed display, the sub-adult were observed the adult males in an upside-down position. The sub-adult also danced, but not as complete as the adult, suggesting that there was a learning process by the sub-adult. This study revealed that the sub-adult/young males of the bird-of-paradise has the ability to dance inherit from their fathers, and then perfect the dance through practice and watching adults. The lek tree surely need to be protected for the survival for this species.
Co-Authors Agung Ramos Agung, M. Untung Kurnia Aisyah Aisyah alfiah alfiah Ani Mardiastuti Ankiq Taofiqurohman Annisa Putri Fitrian Aprilia Permata Sari Ardhiansyah, Rasendriya Naufal Arief, Mochamad Candra Wirawan Asri Peni Wulandari Asri Peni Wulandari, Asri Peni Azmi Azhari Azmi Azhari, Azmi Bai'un, Nurul Hanifah Chandra, Vinoba Dede Supriatna Desi Harneti Putri Huspa Dewi Oktaviani Dhian Ririn Lestari, Dhian Ririn Donny Juliandri Prihadi Emma Rochima Eri Bachtiar Evi Liviawaty Fahrian, Hijrah Fajar Fauzi Abdullah Fiddy Semba Prasetiya Fiddy Semba Prasetiya Galih Bayu Pratama Gustiani - Husnul Khotimah Ibnu Faizal Iis Rostini Iklima Hasanah Indah Riyantini Indah Riyantini Indah Riyantini Jannah, Rodiatul Julaehah, Julaehah Kalysta Fellatami Karimah Syakirotin Kiki Haetami Kindi Farabi Lesta Krismawati Baeha Lestari, Indri Liawati, Liawati Lintang Permata Sari Yuliandi Madaniah AS, Ida Mahdalena Mahdalena Mala Septiani Manshur Awalludin Mega L. Syamsuddin Mochamad Rudyansyah Ismail Mochamad Untung Kurnia Agung Mochamad Untung Kurnia Agung Mochammad Agung Seno Pambudi Muhammad Andhika Pratama Muhammad Untung Kurnia Agung Muhammad Untung Kurnia Agung Mutaqin, Moh Fikri Tanzil Noir P Purba Noir Primadona Purba Norsyehan Nuraini, Eviatun Nurfitriani, Evi Okliandi Saputra Pamungkas, Wahyuniar Pramunandya, Raka Aditya Pratama, Galih Bayu Purbaya, Sari Rega Permana Rizany, Ichsan Rohyati, Rohyati Rudy Kurniadi Saptari, Muhammad Khairan Sari Purbaya Sari, Aprilia Permata Satrio Hadisnugroho Shiono, Yoshihito Solihat, Anisa Sulastri Arsad Sulehah, Sulehah sumarni, nini sunarto sunarto Syawaludin Alisyahbana Harahap Tri Dewi K Pribadi Unang Supratman Vega K. Nurulita Wahyu Syafriansyah Wahyuniar Pamungkas Widyasthana, Ferdiansyah Naufal Yoshihito Shiono Yudi Nurul Ihsan Yuniar Mulyani Zahidah - Zallesa, Sheila Zendina, Luthfia