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Antibacterial Activity of Avicennia Mangrove Yeni Mulyani; Yuniar Mulyani; Aisyah Aisyah
ALCHEMY Jurnal Penelitian Kimia Vol 21, No 2 (2025): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.21.2.100706.180-197

Abstract

The rise of antibiotic resistance presents a major challenge, reducing the efficacy of conventional antibacterial treatments and necessitating the discovery of novel antimicrobial agents. The use of natural products has played a pivotal role in the development of antibiotics. Specifically, marine organisms, with a notable emphasis on mangroves of the genus Avicennia, have played a crucial role in this process. Avicennia marina, Avicennia officinalis, Avicennia alba, and Avicennia germinans have been found to contain secondary metabolites, including flavonoids, tannins, alkaloids, and terpenoids, which exhibit antibacterial properties against drug-resistant pathogens. The review was conducted based on literature published between 2005 and 2025. These compounds act through diverse mechanisms such as disrupting bacterial cell walls, inhibiting protein synthesis, and interfering with quorum sensing and biofilm formation. Evaluations through disk diffusion, microdilution assay, and biofilm inhibition assays have demonstrated the significant antibacterial activity of Avicennia extracts, suggesting their potential as alternative therapeutics in combating resistant bacteria. Future research should focus on enhancing these bioactive compounds’ bioavailability, stability, and large-scale production while addressing potential toxicity and navigating the complex regulatory requirements for drug approval. The continued exploration of Avicennia-derived compounds may contribute to developing novel antibiotics, offering sustainable solutions to antibiotic resistance.
SOSIALISASI MOTIVASI SISWA SISWI SMK RAUDHATUL MU’AWANAH DALAM PROGRAM KREATIFITAS MANAJEMEN KEWIRAUSAHAAN DI ERA DIGITAL Sapari, Sapari; Putra, Feby Arma; Mulyani, Yeni; Alfiah, Siti; Nilawati, Neli
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 12 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Desember 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i12.1986

Abstract

The Motivation Socialization Activity for Students of SMK Raudhatul Mu'awanah in the Entrepreneurial Management Creativity Program in the Digital Era was carried out as an effort to foster entrepreneurial spirit and ability among vocational school students. In today's digital era, many students still have low motivation to be entrepreneurs and tend to be oriented towards being job seekers rather than job creators. In addition, the limited understanding of modern entrepreneurial management concepts and the lack of access to training and assistance in the development of technology-based business ideas are the main problems faced by students. This community service program aims to help students of SMK Raudhatul Mu'awanah in providing motivation and practical understanding of the importance of creativity and innovation in the world of entrepreneurship. Through this socialization activity, students are introduced to modern entrepreneurial management concepts that are relevant to the development of the digital world, such as the use of social media, e-commerce, and digital marketing strategies in building a business. This activity also emphasizes the importance of critical thinking, collaboration, and networking between students, teachers, and local business actors, so as to create an environment that supports the spirit of entrepreneurship. The implementation method is carried out through socialization activities with a participatory approach, in the form of material delivery, interactive discussions, and simple simulations on how to maintain and increase motivation about entrepreneurship creatively through digital. The material covers the basic concepts of motivation, the factors that affect motivation, as well as practical steps such as time management, goal setting, and strengthening the growth mindset. With this method, students not only gain knowledge, but also hands-on experience in understanding the importance of Entrepreneurial Creativity in the Digital Era for their future. The expected results of this activity are increased motivation and interest in students to be creative entrepreneurs through digital roles, the emergence of new technology-based business ideas, and the formation of student entrepreneurship groups (studentpreneur clubs) as a forum for the development of entrepreneurship programs at SMK Raudhatul Mu'awanah. Keywords: Creativity, Entrepreneurship in the Digital Era, SMK Raudhatul Mu'awanah.
PHYLOGENETIC ANALYSIS Pangasionodon hypophthalmus, Pangasius djambal, Pangasionodon gigas, Pangasius sanitwongsei AND HYBRID P. hyphophthalmus X P. djambal Buwono, Ibnu Dwi; Mulyani, Yeni; Soraya, Afa
Jurnal Perikanan Unram Vol 15 No 6 (2025): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v15i6.1999

Abstract

This study aims to identify the types of striped catfish that have genetic variations and genetic relationships among the test striped catfish. Samples of sutchi catfish (P. hypophthalmus) and hybrid P. hyphophthalmus X P. djambal were obtained from Cijengkol and Subang, West Java. P. djambal from Cirata, P. gigas and P. sanitwongsei from ornamental fish shops in Jakarta. The source of genomic DNA was obtained from small pieces of the combined five caudal fins of each test striped catfish sample. Based on the results of amplification using OPA-2 and OPA-3 primers, genetic variations interpreted with the highest number of polymorphic fragments were found in P. sanitwongsei (3 fragments), P. gigas (2 fragments), hybrid P. hyphophthalmus X P. djambal (2 fragments) and P. djambal (1 fragment), respectively. The results of the NTSYS (Numerical Taxonomy and Multivariate Analysis System) program analysis of the OPA-2 and OPA-3 primer amplicons show that the genetic relationship between P. hyphophthalmus, P. djambal, and the hybrid of P. hyphophthalmus X P. djambal and P. sanitwongsei is relatively close (similarity index 71.30%) based on OPA-2 and 55.9% (based on OPA-3). Otherwise, P. gigas is relatively distant (similarity index 44%) based on the OPA-2 primer and 50% (based on the OPA-3 primer). The OPA-2 and OPA-3 primers can be used to detect polymorphisms of striped catfish species.
Molecular Identification of Bacillus Derived from the Common Carp Intestine and Their Antibiotics Resistance Mulyani, Yuniar; Syakirotin, Karimah; Haetami, Kiki; Mulyani, Yeni; Liviawaty, Evi; Agung, Mochamad Untung Kurnia
Jurnal Biodjati Vol 5 No 2 (2020): November
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v5i2.5263

Abstract

The use of bacteria as a biological control agent in aquaculture is such new hope overcoming the negative impacts of the impropriate use of antibiotics. Bacillus is widely known as a potential probiotic for aquaculture, especially which are derived from aquatic biota. Due to a concern that the role of Bacillus as a probiotic agent will be disrupted by residues of antibiotics in the water, this research aimed to identify Bacillus species from common carp intestine based on the molecular method and investigate their resistance to some com-mercial antibiotics that widely used in aquaculture. Chloramphenicol, ampicillin, and metronidazole were used to determine the Bacillus resistance to antibiotics using the Kirby Bauer method. The resistance assay was carried out with a bacterial density of 108 CFU/mL. The results showed that Bacillus isolates derived from common carp  intestine were closely related and resistant to antibiotics. Isolates that resistant to the three types of antibiotics were Cc.1.9 (CgN9) and Cc.2.18 (CgM18).
Co-Authors Agung Ramos Agung, M. Untung Kurnia Agung, Mochamad Untung Kurnia Aisyah Aisyah Aisyah Aisyah alfiah alfiah Ani Mardiastuti Ankiq Taofiqurohman Annisa Putri Fitrian Aprilia Permata Sari Ardhiansyah, Rasendriya Naufal Arief, Mochamad Candra Wirawan Asri Peni Wulandari Asri Peni Wulandari, Asri Peni Azmi Azhari Azmi Azhari, Azmi Bai'un, Nurul Hanifah Chandra, Vinoba Dede Supriatna Desi Harneti Putri Huspa Dewi Oktaviani Dhian Ririn Lestari, Dhian Ririn Donny Juliandri Prihadi Emma Rochima Eri Bachtiar Evi Liviawaty Fahrian, Hijrah Fajar Fauzi Abdullah Feby Arma Putra Fiddy Semba Prasetiya Fiddy Semba Prasetiya Galih Bayu Pratama Gustiani - Husnul Khotimah Ibnu Dwi Buwono Ibnu Faizal Iis Rostini Iklima Hasanah Indah Riyantini Indah Riyantini Indah Riyantini Jannah, Rodiatul Julaehah, Julaehah Kalysta Fellatami Karimah Syakirotin Kiki Haetami Kindi Farabi Lesta Krismawati Baeha Lestari, Indri Liawati, Liawati Lintang Permata Sari Yuliandi Madaniah AS, Ida Mahdalena Mahdalena Mala Septiani Manshur Awalludin Mega L. Syamsuddin Mochamad Rudyansyah Ismail Mochamad Untung Kurnia Agung Mochamad Untung Kurnia Agung Mochammad Agung Seno Pambudi Muhammad Andhika Pratama Muhammad Untung Kurnia Agung Muhammad Untung Kurnia Agung Mutaqin, Moh Fikri Tanzil Nilawati, Neli Noir P Purba Noir Primadona Purba Norsyehan Nuraini, Eviatun Nurfitriani, Evi Okliandi Saputra Pamungkas, Wahyuniar Pramunandya, Raka Aditya Pratama, Galih Bayu Purbaya, Sari Rega Permana Rizany, Ichsan Rohyati, Rohyati Rudy Kurniadi Sapari, Sapari Saptari, Muhammad Khairan Sari Purbaya Sari, Aprilia Permata Satrio Hadisnugroho Shiono, Yoshihito Siti Alfiah Solihat, Anisa Soraya, Afa Sulastri Arsad Sulehah, Sulehah sumarni, nini sunarto sunarto Syakirotin, Karimah Syawaludin Alisyahbana Harahap Tri Dewi K Pribadi Unang Supratman Vega K. Nurulita Wahyu Syafriansyah Wahyuniar Pamungkas Widyasthana, Ferdiansyah Naufal Yoshihito Shiono Yudi Nurul Ihsan Yuniar Mulyani Zahidah - Zallesa, Sheila Zendina, Luthfia