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Antibacterial Potential of Endophytic Fungi from Avicennia marina Against Pathogenic Bacteria Methicillin Resistant Staphylococcus aureus and Pseudomonas aeruginosa Yeni Mulyani; Annastasya Asti Dewi; Nanda Annisa; Nur Asmi Khaerunnisa; Gerardo Gaudentius Sautraja; Adrians Maulana Aziz; Aziz Aprian Pangkerego
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12106

Abstract

Antibiotic resistance has become a global health concern, driving the search for new antibacterial sources. Owing to their ability to biosynthesize diverse bioactive secondary metabolites, endophytic fungi isolated from mangrove plants have emerged as a sustainable resource for natural antibacterial compounds. This study aimed to evaluate the antibacterial activity of endophytic fungi isolated from Avicennia marina collected from the Nusawiru Mangrove Conservation Area, Pangandaran, Indonesia. Isolation was performed using the direct plating method on Potato Dextrose Agar (PDA), followed by purification to obtain six pure isolates. The isolates were screened for antibacterial activity against Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa using an agar plug diffusion assay. Among the six isolates obtained, only AVM BT 4.2 exhibited antibacterial activity against MRSA, producing total inhibition zones of 15.77 ± 1.51 mm at 24 h and 15.39 ± 0.73 mm at 48 h, categorized as strong inhibition. However, none of the isolates inhibited P. aeruginosa. These findings indicate the potential of A. marina endophytic fungi as a source of antibacterial compounds against resistant bacteria and support further studies on molecular identification and bioactive metabolite characterization of secondary metabolites from the active isolates to support the development of natural antibiotic candidates based on sustainable coastal biological resources.
EXPLORATION OF THE BIOACTIVE POTENTIAL OF RHIZOPHORACEAE MANGROVE PLANTS: IMPLICATIONS IN THE FIELD OF FISHERIES Yuniar Mulyani; Yeni Mulyani; Aisyah Aisyah
Vol 15 No 2 (2025): JURNAL PERIKANAN
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jp.v15i2.1395

Abstract

Mangrove forests, as coastal ecosystems rich in biodiversity, play an important role in ecology and the fisheries sector. Mangroves not only function as coastal protectors and habitats for aquatic organisms but also produce bioactive compounds that have potential as antibacterial, antioxidant, antifungal, and antiviral agents. Research on mangrove plants from the Rhizophoraceae family, such as Bruguiera, Kandelia, Ceriops, and Rhizophora, has shown that compounds like flavonoids, tannins, alkaloids, and saponins have significant biological activities. Flavonoids act as antimicrobials, while tannins inhibit bacterial growth by precipitating proteins. Alkaloids disrupt bacterial cell walls and have potential in combating cancer cells. Studies also reveal significant antioxidant activity, with some mangrove extracts showing great potential in combating free radicals. Moreover, these compounds offer potential in reducing reliance on synthetic antibiotics for the treatment of cultured fish diseases and provide opportunities for the development of natural-based health products. This review aims to integrate recent findings on the bioactivity of mangrove plants and propose innovative applications of bioactive compounds in fisheries and conservation with a focus on ecosystem sustainability and optimal use of natural resources.
Co-Authors Adrians Maulana Aziz Agung Ramos Agung, M. Untung Kurnia Aisyah Aisyah Aisyah Aisyah alfiah alfiah Ani Mardiastuti Ankiq Taofiqurohman S Annastasya Asti Dewi Annisa Putri Fitrian Aprilia Permata Sari Asri Peni Wulandari Aziz Aprian Pangkerego Azmi Azhari Azmi Azhari, Azmi Bai'un, Nurul Hanifah Chandra, Vinoba Dede Supriatna Desi Harneti Putri Huspa Dewi Oktaviani Dhian Ririn Lestari, Dhian Ririn Donny Juliandri Prihadi Emma Rochima Eri Bachtiar Evi Liviawaty Fahrian, Hijrah Fajar Fauzi Abdullah Feby Arma Putra Fiddy Semba Prasetiya Fiddy Semba Prasetiya Galih Bayu Pratama Gerardo Gaudentius Sautraja Gustiani - Husnul Khotimah Ibnu Faizal Iis Rostini Iklima Hasanah Indah Riyantini Indah Riyantini Indah Riyantini Jannah, Rodiatul Julaehah, Julaehah Kalysta Fellatami Karimah Syakirotin Kiki Haetami Kindi Farabi Lesta Krismawati Baeha Lestari, Indri Liawati, Liawati Lintang Permata Sari Yuliandi Madaniah AS, Ida Mala Septiani Manshur Awalludin Mega L. Syamsuddin Mochamad Rudyansyah Ismail Mochamad Untung Kurnia Agung Mochammad Agung Seno Pambudi Muhammad Andhika Pratama Muhammad Untung Kurnia Agung Muhammad Untung Kurnia Agung Mutaqin, Moh Fikri Tanzil Nanda Annisa Nilawati, Neli Noir P Purba Noir Primadona Purba Norsyehan Nur Asmi Khaerunnisa Nuraini, Eviatun Nurfitriani, Evi Okliandi Saputra Pramunandya, Raka Aditya Pratama, Galih Bayu Purbaya, Sari R. Mochamad Candra Wirawan Arief Rega Permana Rizany, Ichsan Rohyati, Rohyati Rudy Kurniadi Sapari, Sapari Sari Purbaya Sari, Aprilia Permata Satrio Hadisnugroho Shiono, Yoshihito Siti Alfiah Solihat, Anisa Sulastri Arsad Sulehah, Sulehah sumarni, nini sunarto sunarto Syawaludin Alisyahbana Harahap Tri Dewi K Pribadi Unang Supratman Vega K. Nurulita Wahyu Syafriansyah Wahyuniar Pamungkas Yoshihito Shiono Yudi Nurul Ihsan Yuniar Mulyani Zahidah Zahidah Zallesa, Sheila