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All Journal International Journal of Public Health Science (IJPHS) Jurnal Sain Veteriner Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Journal of Agromedicine and Medical Sciences Biology, Medicine, & Natural Product Chemistry Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) UNEJ e-Proceeding MNJ (Malang Neurology Journal) Universa Medicina Paediatrica Indonesiana Journal Of Vocational Health Studies Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya NurseLine Journal Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner Journal of Health Sciences JHECDs: Journal of Health Epidemiology and Communicable Diseases JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Nursing and Health Sciences Journal (NHSJ) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat Jember Medical Journal (JMJ) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) Journal of Agropharmacy ASPIRATOR - Journal of Vector-Borne Diseases Studies JI-KES (Jurnal Ilmu Kesehatan)
Yunita Armiyanti
Department Of Parasitology Faculty Of Medicine University Of Jember, Jember, Indonesia
Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Elephantiasis and nodular scabies coinfection: a rare case report Armiyanti, Yunita; Shodikin, Muhammad Ali; Tohari, Achmad Ilham
Paediatrica Indonesiana Vol. 65 No. 5 (2025): September 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.5.2025.438-42

Abstract

Indonesia  is a tropical country and  home to many infectious diseases. Two of them are filariasis and scabies. The coinfection of filarial infection and scabies may cause severe morbidity for the patient, especially children. There has been no reported coinfection or management between these two diseases. An 11-year-old boy was brought to the pediatrics division of Dr. Soebandi Hospital with diffuse enlargement of the left lower extremity and scrotum, along with non-pitting edema, itching, and nodular skin lesions all over the body. It is important to consider holistic approaches to prevent further morbidity and disability.
Correlation of Soil Contamination and Incident of STH Infection in Sukokerto Village Sukowono District Jember Regency Hermansyah, Bagus; Armiyanti, Yunita; Utami, Wiwien Sugih; Rahmi, Aulya; Aziz, Ayu Munawaroh
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.18731

Abstract

The most common worm infections are those caused by soil-transmitted helminths (STH) infection. Soil contamination is one of the causes of helminth transmission to humans. Poor environmental sanitation and personal hygiene facilitate the spread and transmission of STH. Jember is a district where the majority of the population lives in rural areas with poor sanitation access. This study aims to determine the correlation between soil contamination and incident of STH infection in Sukokerto Village, Sukowono District, Jember Regency. This cross-sectional analytic observational study was conducted from August 2022 to February 2023. The total of samples in this study was 44 fecal and soil around the house. The data obtained from the laboratory examination showed that the total fecal positive of STH was 11 or 25%, and soil was 13 or 29.5%. The results of the Chi-Square test analysis obtained ρ<0.05 (ρ=0.036, OR=4,457). The results showed a significant relationship between soil contamination and the incidence of STH infection in Sukokerto Village, Sukowo District, Jember Regency
Determinant of Water Source Contamination by Soil Transmitted Helminths in Rural Areas of Jember District Armiyanti, Yunita; Mash’ab Zirrun Al-Qomah; Angga Mardro Raharjo; Bagus Hermansyah; Wiwien Sugih Utami
BKM Public Health and Community Medicine The 12th UGM Public Health Symposium
Publisher : Universitas Gadjah Mada

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Abstract

Purpose: This study aims to identify STH eggs and larvae that contaminate water sources in rural areas of Jember and their risk factors. Method: This type of study is an observational analytic study with a cross-sectional approach. Samples from water sources in Mumbulsari and Sukowono districts were taken on inclusion criteria under flotation and sedimentation methods and totaled 56 samples. Respondents were interviewed on account of risk factors related to the presence of STH in water sources using a questionnaire and a total of 56 respondents. Result: The results showed that the common type of STH found was Hookworm (92.31%). The most polluted water source is river (53.84%). Based on the characteristics, the majority of respondents are female (67.86%), aged over 40 years (58.93%), have low education (57.15%), and have no job (51.79%). Found a relationship using chi-square between bowel habits and the presence of STH eggs and larvae (ρ > 0.05). Conclusion: This study proved that STH eggs and larvae can contaminate water sources such as rivers and wells The contamination is related to the habit of defecating not in latrines, so the important prevention for STH infection in water sources is to change the habit of defecation into a healthy habit.
Potensi Antimalaria Fraksi-Fraksi Daun Kembang Bulan (Tithonia diversifolia [Hemsley] A. Gray) Nuri; Wicaksono, Yudi; Rahardi, Verdian; Utami, Wiwien Sugih; Armiyanti, Yunita
Journal of Agropharmacy Vol. 1 No. 1 (2024)
Publisher : Faculty of Pharmacy, University of Jember

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Abstract

Kembang bulan (Tithonia diversifolia [Hemsley] A. Gray) has been used in traditional medicine to treat malaria. Previous research results showed that the ethanol extract of kembang bulan leaves had antimalarial activity in vivo with an ED50 of 113.39 mg/kgBW. Until now, the compounds with antimalarial activity in vivo are unknown. The initial stage that can be done to separate the compounds in the extract is fractionation. This study aims to separate the extract into fractions and test its antimalarial activity. Fractionation was carried out using a vacuum liquid chromatography method using a stationaryphase of silica gel GF254 and a mobile phase of n-hexane, chloroform and methanol in a gradient. In vivo antimalarial activity was tested using the Peter test method. Fractionation produces 5 fractions, each yield is 1.9; 2.1; 17.6; 60.8, and 17.6% respectively for fractions 1-5. The results of the antimalarial activity test for fractions 1-5 with a dose of 2 mg/kgBW showed inhibition of the growth of Plasmodium berghei respectively at 52.3 ± 1.4; 83.5±1.4; 74.6±1.2; 69.5±0.9; 44.8 ± 0.3%. Fraction 2 with the greatest resistance was tested further and showed an ED50 value of 0.52 mg/kgBW.
B-cell epitope prediction of MPB83 protein as a candidate for serodiagnostic antigen of bovine tuberculosis in human: In silico study Ahmad, Shabrina Izzata Afiyati; Aziz , Ayu Munawaroh; Armiyanti, Yunita; Mufida, Diana Chusna
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art4

Abstract

Background: Bovine tuberculosis (bTB) can be transmitted to humans by inhalation or consumption of incomplete pasteurized milk and dairy products derived from infected cows. Most cases of Mycobacterium tuberculosis (M. bovis) infection are resistant to tuberculosis (TB) drugs. The risk of death during treatment for bTB has been reported to be 2.55 times higher than for TB. However, the quality of diagnostic methods for bTB remains relatively low.Objective: We aim to evaluate the potential of the B-cell epitope of the MPB83 protein as a candidate bTB serodiagnostic antigen using an in silico approach. Methods: This study was a computer-based descriptive study using secondary data from the National Center for Biotechnology Information (NCBI) protein database. The MPB83 protein sequence was obtained from M. tuberculosis variant bovis AF2122/97 from the United Kingdom. We described the characteristics of the linear epitope of the M. bovis B-cell protein MPB83 by measuring antigenicity, molecular weight, instability index, and Grand Average of Hydropathy (GRAVY) score. The tools used in this study were IBIVU PRALINE, VaxiJen v2.0, IEDB, ExPASy ProtParam, Cluspro, and the PyMOL application.Results: We found an epitope that could be used for bTB serodiagnostic antigen with low conservation, the 106KLNPDVNLVDTLN118 epitope. It has the molecular weight, instability index, and GRAVY score of 1638.76 Da, -28.44, and -0.300, respectively. Epitopes with the best criteria were simulated by docking to human major histocompatibility complex (MHC) class II. Docking results showed that the lowest binding energy was -644.8 kcal/mol. Further analysis using the PyMOL application obtained 14 hydrogen bonds with bond distances ranging from 1.7 Å to 2.2 Å, all of which showed strong hydrogen bonds.Conclusion: The B-cell epitope of MPB83 protein sequence 106KLNPDVNLVDTLN118 has a potential serodiagnostic antigen candidate for human bTB.
Spatial analysis of tuberculosis cases among stunted toddlers in Rambipuji District, Jember Regency Utami, Wiwien Sugih; Amrina, Adinda Putri Yusri; Armiyanti, Yunita; Maududie, Achmad
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art8

Abstract

Background: The ongoing prevalence of tuberculosis (TB) and stunting presents significant health challenges, frequently localized within specific regions of Indonesia. Spatial analysis is essential in controlling infectious diseases like TB, as it identifies disease clusters and patterns of local TB spread within an area. Objective: This study aimed to analyze the distribution of TB cases among stunted children through spatial analysis. Methods: We used a cross-sectional analytical descriptive study. We interviewed parents of stunted children using a questionnaire. The diagnosis of TB was made based on the pediatric TB scoring table. Coordinate data of sample sites were obtained using a Geographic Information System (GIS), supported by risk factor analysis of TB. We then created a disease distribution map using the spatial analysis by Moran's Index and Nearest Neighbor Index (NNI) methods. Results: There were 15 childhood TB cases (8.2%) among stunted children in Rambipuji District. The spatial autocorrelation test using Moran's index showed that TB cases were clustered in Rambigundam village (Moran’s index 0.2364, p-value <0.05 and Z-score >1.96). The results of the NNI analysis showed dispersed results (p-value=0.000) in all villages. Conclusion: The distribution of childhood TB cases among stunted children in Rambipuji District is primarily random, except for Rambigundam Village, which shows a clustering of cases. According to the NNI methods, childhood TB cases among stunted children are spreading throughout all villages. These results underscore the need for initiatives to curb TB transmission, especially among stunted children, which should be targeted at all villages.
Preliminary Investigation of Association Between Sanitation and Water Contamination by Cryptosporidium at Livestock Area in Jember Nurdian, Yudha; Fitriyah, Ainun Nadiratul; Rachmawati, Dwita Aryadina; Yunita Armiyanti
Nursing and Health Sciences Journal (NHSJ) Vol. 4 No. 3 (2024): September 2024
Publisher : KHD-Production

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53713/nhsj.v4i3.348

Abstract

Cryptosporidium sp. is one of the waterborne protozoa involving water as the main medium of transmission causing cryptosporidiosis in animals and humans and its presence is influenced by various things including hygiene and sanitation of the community. This cross-sectional study aims to determine the association between the implementation of the community-led total sanitation and the presence of Cryptosporidium oocysts in clean water sources. The research was conducted from October 2020 to June 2021 in Sukokerto Village, Sukowono, Jember Regency. The data were obtained from interview with the respondents using structured questionnaires. The presence of oocysts was examined by microscopic observations with sedimentation methods and Modified Ziehl=Neelsen staining, and the data were analyzed using Spearman rho statistical test. The results showed that there were 12 (20.3%) household with good category at the implementation of community-led total sanitation, 28 (47.5%) household with moderate category, and 19 (32.2%) household with poor category. The presence of Cryptosporidium oocysts was found in 6 (10.2%) samples of clean water sources. The results of statistical tests with Spearman rho showed a p-value=0.098, so that there was no significant association between the implementation of community-led total sanitation and the presence of Cryptosporidium oocysts in clean water sources in study location.
The Relationship between Sanitation and Personal Hygiene with Seroprevalence of Toxoplasmosis in Pregnant Women at Kaliwates and Banjarsengon Community Health Centers Nabila Putri Anissa; Yunita Armiyanti; Eny Nurmaida; Bagus Hermansyah; Erma Sulistyaningsih; Wiwien Sugih Utami
Journal of Agromedicine and Medical Sciences Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Jember

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Abstract

Toxoplasmosis is an infectious disease in animals that can be transmitted to humans. Sanitation and personal hygiene are risk factors for toxoplasmosis. Toxoplasmosis can be transmitted from pregnant women to their fetuses. Toxoplasmosis in pregnancy can cause pregnancy, premature birth, and congenital toxoplasmosis. According to the Jember District Health Office in 2023, access to proper sanitation and good hygienic behavior is still low. The purpose of this study was to analyze the relationship between sanitation and individual hygiene with toxoplasmosis seroprevalence in pregnant women at the Kaliwates and Banjarsengon Health Centers. This study used a crosssectional study type. The subjects of the study were 65 pregnant women at the Kaliwates and Banjarsengon Health Centers who were taken using the accidental sampling technique. The serological examination used the Toxoplasma IgM and IgG ELISA kit from Calbiotech®. The results of this study showed that 77% of pregnantwomen were detected positive for toxoplasmosis. The majority of pregnant women have good sanitation and personal hygiene categories of 87.7% and 90.8%, respectively. Based on the results of Fisher's exact test, sanitation and personal hygiene are not related to toxoplasmosis seroprevalence (p>0.05). This study concludes that sanitation and personal hygiene of pregnant women at the Kaliwates and Banjarsengon Health Centers are not significantly related to toxoplasmosis seroprevalence.  
Gangguan Pertumbuhan Janin sebagai Dampak Menurunnya Kesehatan Gigi dan Mulut Ibu Hamil Mei Diastutik, Vike; Rahmawati, Iis; Armiyanti, Yunita
JI-KES (Jurnal Ilmu Kesehatan) Vol. 7 No. 2 (2024): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/jikes.v7i2.769

Abstract

Abstrak Angka kejadian karies gigi dan gingivitis sering terjadi pada wanita hamil. Sekitar 60 hingga 75% wanita hamil menderita gingivitis, mengabaikan kesehatan mulut dan gigi selama kehamilan, sehingga menyebabkan kerusakan gigi, radang gusi, plak gigi, dan periodontitis. Kondisi tersebut memiliki efek buruk pada ibu hamil dan bayinya. Tujuan penelitian untuk mengetahui pengaruh kesehatan gigi dan mulut ibu hamil terhadap pertumbuhan janin. Penelitian dilakukan di Kabupaten Probolinggo pada bulan September 2023. Penelitian ini merupakan penelitian observasional analitik dengan desain penelitian cross-sectional. Teknik pengumpulan data menggunakan kuesioner dan rekam medis/buku KIA dari Januari sampai Mei 2023. Variabel independent adalah kesehatan gigi dan mulut ibu hamil. Variabel dependent adalah pertumbuhan janin. Populasi yaitu semua ibu hamil sebanyak 21.212 orang. Sampling menggunakan simple random sampling. Sampel yaitu Sebagian ibu hamil sebanyak 96 orang. Analisis bivariat menggunakan chi-square. Hasil penelitian menunjukkan sebagian besar status kesehatan gigi dan mulut ibu hamil sehat sejumlah 67 ibu hamil (70%). Sebagian besar pertumbuhan janin normal yaitu 54 ibu hamil (56%). Ada pengaruh kesehatan gigi dan mulut ibu hamil terhadap pertumbuhan janin.Upaya yang dapat dilakukan yaitu tenaga kesehatan memberikan penyuluhan kepada ibu hamil tentang kesehatan gigi dan mulut yang juga dapat berpengaruh terhadap pertumbuhan janin. Kata kunci: kesehatan gigi dan mulut, kehamilan, pertumbuhan janin, tinggi fundus uteri (TFU)   Abstract Pregnant women are frequently at risk for gingivitis and dental cavities.  About 60 to 75% pregnant women suffer gingivitis, neglecting oral and dental health during pregnancy, resulting in tooth decay, gingivitis, dental plaque, and periodontitis. This condition has bad effects on expectant mother and babies. The aim research is determine effect expectant mother’s dental and oral health fetal growth. The research was conducted in Probolinggo Regency in September 2023. This research was analytical observational study with cross-sectional design. Data collection techniques used questionnaires and medical records/KIA books from January to May 2023. The independent variable was dental and oral health pregnant. The dependent variable fetal growth. There are 21,212 expectant mothers in the population. Basic random sampling is used in sampling. The sample consisted of 96 expectant mother. Bivariate analysis using chi-square.The majority of the study's participants, 67 expectant mother (70%), had good dental and oral health. Of the 54 expectant mother (56%), the majority had normal fetal growth. The oral and dental health of expectant mother affects the growth of the fetus. Health professionals might try to inform expectant mother about the relationship between dental and oral health and fetal development. Keywords: dental and oral health, pregnant, fetal growth, fundus uteri height (TFU)
High Toxoplasmosis Seroprevalence and Anemia Among Early-Mid Pregnant Women in Jember, Indonesia Wulandari, Lindi Priyantika Tri; Armiyanti, Yunita; Aziz, Ayu Munawaroh; Hermansyah, Bagus; Sulistyaningsih, Erma; Utami, Wiwien Sugih
Journal of Community Medicine and Public Health Research Vol. 6 No. 2 (2025): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v6i2.68484

Abstract

Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii, which can be transmitted through various routes. Toxoplasmosis in pregnant women may cause abortion and fetal disabilities. Decreased body immunity due to anemia can increase the risk of toxoplasmosis during pregnancy. The purpose of this study was to identify the characteristics of pregnant women and their association with anemia, determine the prevalence of anemia and toxoplasmosis infection in pregnant women, and investigate whether anemia is a risk factor for toxoplasmosis in pregnant women. This research is an analytical, observational study using a cross-sectional laboratory examination. The sample in this study consisted of blood collected from first- and second-trimester pregnant women at the Kaliwates and Banjarsengon Public Health Centers for hemoglobin analysis and toxoplasmosis serology. Accidental sampling was conducted from July to December 2024. The research data were presented in tabular form and analyzed using the Chi-square test. This study was conducted on 65 pregnant women. The number of pregnant women with anemia was 43% and the number of pregnant women who were positive for toxoplasmosis was 66%. A significant association exists between gestational age and anemia (p-value = 0,041). Bivariate analysis between anemia and T. gondii infection showed no significant association (p-value = 0.182). This study concludes that anemia is not proven to be a risk factor for toxoplasmosis infection in pregnant women. However, the cases of anemia and toxoplasmosis were high and require specific attention.
Co-Authors Achmad Maududie Adinda Putri Yusri Amrina Adrial Adrial Ahmad Hasbi Al-Muzaky Ahmad Hasbi Al-Muzaky Ahmad, Shabrina Izzata Afiyati Ali Machrus Amrina, Adinda Putri Yusri Andriani, Made Prasanti Angga Mardro Raharjo Anisah Ardiana Anthia Ayu Nandira Ardyansyah, Rizky Robeth Aulya Rahmi Ayundasari, Asti Ayundasari, Asti Azham Purwandhono Aziz , Ayu Munawaroh Aziz, Ayu Munawaroh Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Bagus Hermansyah Brillian Adexa Yudinda Cholis Abrori, Cholis Cicih Komariyah Desi Dwi Cahyani Diana Chusna Mufida Dicky Setiawan Dina Helianti Dini Agustina Drajad, Rahadinda Mutia Dhamar Dwita Aryadina Rachmawati Edi Widjajanto Elly Nurus Sakinah Elvia Rahmi Marga Putri Enny Suswanti ENNY SUSWATI Eny Nurmaida Epafroditus Sanjaya Adiguna Erfan Efendi Erma Sulistyaningsih Erma Sulistyaningsih Evi Umayah Ulfa Febrianti, Zahrah Fitri, Nadya Eka Fitriyah, Ainun Nadiratul Ghaiska Najma Amnur Hanu Neda Septian Heni Fatmawati Hermansyah, Bagus Hidayat Teguh Wiyono Himma, Alyatul Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Imtiyaz, Andi Hilman Irawan Fajar Kusuma Ivan Iqbal Baidowi Jauhani, M. Afiful Kartika Senjarini Kholifaturrohmah, Sakinatus Sariroh Kholifaturrohmy, Muhammad Rizqi Komang Yunita Wiryaning Putri Kristianningrum Dian Sofiana Laily Nurhayati Laksmi Indreswari Leersia Yusi Ratnawati Loeki Enggar Fitri M. Ali Shodikin Mash’ab Zirrun Al-Qomah Mei Diastutik, Vike Mirawati Moh Mirza Nuryady, Moh Mirza Muhammad Afiful Jauhani Muhammad Afiful Jauhani Muhammad Alif Taryafi Nabil Athoillah Nabila Putri Anissa Nanda Nuramna Nidya Husna Kholidah Nihayah Lukman Nisrina Salsabila Firmansyah Nita Alfianti Nizar Fiska Bayu Agustian Nuri Nurmaida, Eny Nurmaida, Eny Nurus Saffana Yulianto Pangestu, Ahmad Yudho Hadi Primadana, Aditya Rachmawati, Dwita Aryadina Rahardi, Verdian Rahardjo, Angga Mardro Rahmadhan, Adiz Dwiputra Rahmawati, Iis Rahmi, Aulya Ramadanti, Novi Awalia Ramadhani, Rafindra Ratnawati, Leersia Yusi Rezza Putri Mahartika Rini Riyanti Risyanto, Chusnul Aulia Arisny Putri Rohmah, Etik Ainun Rosita Dewi Sa'bani, Begawan Saiful Akhyar Lubis Salsabilla, Safira Putri Nur Saputra, Antonius Dwi Sheilla Rachmania, Sheilla Sugeng Setyo Utomo, Sugeng Setyo Sulistyaningsih, Erma Syamsuddin, Alif Fazduani Teguh Wahju Sardjono Teguh Wahju Sardjono Tohari, Achmad Ilham Widhiasari Normaningtyas Wiwien Sugih Utami Wulandari, Lindi Priyantika Tri Yoga Setyo Yudha Nurdian Yudha Nurdian Yudi Wicaksono Zahrah Febianti Zulaikha Rizqina Rahmawati