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All Journal IJOG : Indonesian Journal on Geoscience Metodik Didaktik JPI Pendas : Jurnah Ilmiah Pendidikan Dasar Jurnal Bidan Cerdas INTI Nusa Mandiri JATI (Jurnal Mahasiswa Teknik Informatika) Optika : Jurnal Pendidikan Fisika Heart Science Journal JOURNAL OF BUSINESS AND ECONOMICS RESEARCH (JBE) IQ (Ilmu Al-qur'an): Jurnal Pendidikan Islam Edu Consilium : Jurnal Bimbingan dan Konseling Pendidikan Islam PAEDAGOGY : Jurnal Ilmu Pendidikan dan Psikologi Bulletin of Science Education Counseling Milenial (CM) INTERNATIONAL JOURNAL OF EDUCATION, INFORMATION TECHNOLOGY, AND OTHERS Jurnal Klinik dan Riset Kesehatan Jurnal Pendidikan dan Pembelajaran Sekolah Dasar (JPPSD) Jurnal Inovasi Pembangunan REDUPLIKASI: Jurnal Penelitian Pendidikan Bahasa Indonesia Jurnal Mahasiswa Karakter Bangsa Elektriese: Jurnal Sains dan Teknologi Elektro Sustainability (STPP) Theory, Practice and Policy Jurnal Pengabdian Masyarakat Bhinneka Journal of Management, Economic and Accounting (JMEA) Yurisprudentia: Jurnal Hukum Ekonomi Innovative: Journal Of Social Science Research Jurnal Sains Natural AMPLITUDO: Journal of Science & Technology Innovation Teaching, Learning, and Development
Novi Rahmawati
Master in Planning and Management of Coastal Area and Watershed, Faculty of Geography, Gadjah Mada University, Bulaksumur, Yogyakarta
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Journal : Heart Science Journal

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Navigating pulmonary hypertension: Echocardiography insight into right ventricular function and dynamics Rahmawati, Novi; Yogibuana, Valerinna
Heart Science Journal Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.04.4

Abstract

Pulmonary hypertension (PH) is a pathophysiological disorder characterized by pulmonary vascular remodeling and dysfunction, which may arise in various clinical contexts, particularly in association with cardiovascular and respiratory diseases. PH is characterized by a mean pulmonary arterial pressure (mPAP) exceeding 20 mmHg at rest as determined by hemodynamic assessment via right heart catheterization (RHC), which remains the gold standard for diagnosis. Transthoracic echocardiography (TTE) is recommended as a non-invasive screening tool for the initial evaluation of individuals presenting with symptoms, risk factors, or clinical suspicion of PH. Echocardiography enables the identification of pulmonary hypertension by assessing right ventricular (RV) dysfunction and increased RV pressure overload. A comprehensive assessment of the RV’s dimensions and function is essential in all individuals with PH, given that mortality in PH is correlated with the severity of RV dysfunction. While RHC remains the definitive diagnostic modality for PH, echocardiography provides a valuable, widely available, and non-invasive alternative for estimating pulmonary artery pressures, assessing RV function, and stratifying disease severity, in alignment with current guidelines from the European Society of Cardiology (ESC) and the European Respiratory Society (ERS).
The hidden grip: A case of secondary hypertension entwined with renal artery stenosis Rahmawati, Novi; Handari, Saskia Dyah; Hargiyanto, Erlangga Diasmara
Heart Science Journal Vol. 7 No. 1 (2026): Accelerating Clinical Breakthroughs: The Journey from Molecular Discovery to Pa
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.01.20

Abstract

Background: Renal artery stenosis (RAS) is a vascular disorder characterized by narrowing of the renal artery. It often leads to renovascular hypertension (RVH) and, if untreated, progression to end-stage renal disease. Atherosclerosis and fibromuscular dysplasia (FMD) are the most common etiologies, with clinical manifestations ranging from asymptomatic to resistant hypertension. Diagnosis involves imaging modalities such as Doppler ultrasound (DUS), CT angiography (CTA), and confirmation by digital subtraction angiography (DSA). We report a case to emphasize the diagnostic and therapeutic challenges of RAS in young patients. Case Illustration: A 17-year-old male presented with persistent grade 2 hypertension unresponsive to dual antihypertensive therapy and a history of repeated hospitalizations. Imaging revealed significant stenosis with post-stenotic dilatation in the right renal artery. CTA and DSA confirmed the diagnosis of RVH secondary to RAS, with Fibromuscular Dysplasia (FMD) as the suspected etiology. The patient underwent successful angioplasty and stenting, resulting in improved blood pressure control and reduced medication requirements. Upon follow-up, the patient’s symptoms have resolved, and their blood pressure is under control. RAS remains a challenging and underdiagnosed cause of secondary hypertension, particularly in younger patients. While optimal medical therapy is the first-line approach, it may be insufficient in high-risk individuals. Non-invasive modalities provide valuable initial assessment, but DSA remains the gold standard for diagnosis and intervention. Revascularization, especially via stenting, is recommended in selected cases with significant stenosis, viable renal tissue, and resistant hypertension. Guidelines emphasize tailored therapy and careful post-procedure monitoring to detect restenosis or symptom recurrence. This case underscores the importance of early recognition and individualized intervention to improve outcomes.. Conclusions: RAS should be considered in young patients with grade 2 hypertension. Early diagnosis and appropriate intervention are critical to preventing long-term renal and cardiovascular complications.
Co-Authors Adawiyah, Robiah ADRIA ADRIA, ADRIA Affriani, Asri Ria Agus Wibowo Agustin, Helen Bela Amani, Safira Aprindhiya, Bunga Aulia Syaputri, Ambar Awaliyah, Siti Nafa Ayu Agustina Azizah, Auliatul Azizah, Syarifah Y Nur Batubara, Efrida Handayani Bayuni, Tia Citra Cucun Sunaengsih, Cucun Deasy Arisanty DEWI SARTIKA Dewi, Shonia Rachma Elvani Hertati Elvira Mustikawati Putri Hermanto Esti Untari Fadah, Hanim Isti Fadilah, Mochamad Fathonah, Iir Nikmatul Fatma, Ida Gultom, Yosafat Hadi Pranoto Hargiyanto, Erlangga Diasmara Hariyanto, Intan Amelia HERA, TRENY I Ketut Mahardika Indra Prasetya Indrasetianingsih, Artanti Irma Purnamasari, Ade Jaiz, Ahmad Kaneishia, Sabrina Keswani, Anjeni Fatiha Galuh laili, ummiy Fauziah Laksana, Eko Listiarini, Yuni M. A. Marfai Magfiroh, Nafilah Mahmudyah, Niken Noviana Markus Idulfilastri, Rita Maryani - Maulana, M. Mi, Rah Mohamad Ilham Muhajir Muhajir, Muhajir Mutiara, Hartanti Sinta Nazarina, Ameylia Nurfatimah Nurfatimah Nurmanita , Gina Nursilawati, Nadya Octaviani, Indri Prastya, Andhika Primasatria Edastama, Primasatria Puspita, Erika Wanda Rahayu, Kisworo Ristiaha, Kiki Ristiaha Rizkina Ramadhani, Layda Rosdiana, Nazwa S Siswanto Safitri, Riya Salsabila, Nabila Saskia Dyah Handari Sholehatennafiah, Vivi Sinta Mayasari, Sinta Sri Estu Winahyu Subiki Subriah, Subriah Sudarti Sudarti Sugiharto, Puja Syaprya, Widya Dwi TITIN SUNARYATI Trapsilo Prihandono Triatmojo, Nicodemus Utami, Sonia Anisah Widia Astuti Yogibuana, Valerinna Yulianto, Rany Angeline Yushardi Yushardi, Yushardi