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All Journal International Journal of Public Health Science (IJPHS) Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Pharmascience Science and Technology Indonesia Ilmu Gizi Indonesia Indonesian Journal of Chemistry JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Indonesian Journal of Halal Research Journal of halal product and research (JHPR) Community Empowerment Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Jurnal Kajian Islam Modern Journal of Halal Science and Research Open Community Service Journal Riwayat: Educational Journal of History and Humanities Journal of Food and Pharmaceutical Sciences Medical Sains : Jurnal Ilmiah Kefarmasian
Nina Salamah
Fakultas Farmasi, Universitas Ahmad Dahlan
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Veterinary Other

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Autentikasi Minyak Biji Jagung Zea mays L.: Pengaruh Metode Ekstraksi dan Analisis Komposisi Menggunakan Metode Gas Cromatoghraphy-Mass Spectrometry (GC-MS) Justitia Cahyani Fadli; Any Guntarti; Nina Salamah
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 9, No 2 (2024)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v9i2.85367

Abstract

Minyak jagung mengandung protein dan asam lemak yang melimpah, sehingga diperlukan metode dan kondisi ekstraksi yang tepat untuk menghasilka kualitas minyak berkualitas tinggi. Minyak dapat diperoleh dengan cara pemanasan menggunakan alat Soxhlet maupun Reflux dan akan terisolasi dengan pelarut non polar. Penelitian ini bertujuan untuk mengoptimalkan ekstraksi minyak jagung manis, membandingkan kualitas minyak jagung dari dua metode isolasi serta menganalisis komposisi asam lemak menggunakan GC-MS. Minyak jagung manis yang dihasilkan dari dua metode isolasi Reflux dan Soxhlet dibandingkan dengan parameter SNI dan diidentifikasi komposisi asam lemaknya menggunakan instrumen GC-MS. Parameter kualitas minyak biji jagung manis yang dihasilkan dari metode Soxhlet dan Reflux, memiliki karakteristik warna, bau, indeks bias, kadar air, bilangan asam, bilangan peroksida, dan bilangan iod yang memenuhi persyaratan SNI. Hasil analisis GC-MS menunjukkan metode Reflux menghasilkan 3 kandungan senyawa yaitu, asam palmiat (31,37%), linoleoyl chloride (67,15%), dan asam ftalat (1,48%), sedangkan metode Soxhlet menghasilkan 2 kandungan senyawa, yaitu asam palmiat (32,28%) dan asam linoleat (66,89%). Hasil penelitian menunjukkan bahwa variasi metode ekstraksi minyak biji jagung memengaruhi kualitas minyak serta kandungan asam lemak yang dihasilkan. 
Analysis of Gelatin on Soft Candy using a Combination of Fourier Transform Infrared Spectroscopy (FTIR) with Chemometrics for Halal Authentication Salamah, Nina; Jufri, Sayyidah Luthfiyah; Susanti, Hari; Jaswir, Irwandi
Indonesian Journal of Halal Research Vol. 5 No. 2 (2023): August
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ijhar.v5i2.25682

Abstract

The main ingredients of soft candies are gelatin made from the skin/bones of cows and pigs, i.e. bovine and porcine gelatin. This research aims to analyze the present bovine and porcine gelatin in soft candy using a fast and low-cost method. The method used is a combination of FTIR and chemometrics. The reference candy samples were made with formulation porcine gelatin concentrations of 15, 30, 45, 60, 75, 90 and 100%. As a control, we used a bovine gelatin reference candy. All the candy samples were measured with FTIR in the reflection mode in the wavenumber range from 4000 to 500 cm-1. Data analysis was carried out using the chemometric method with the Minitab 18 application. PLS calibration results in y = 0, 99999x + 0.000396 indicate a good correlation. The value of R2 = 0.99999 and the RMSEC of 0.03%. Internal validation with R2 = 0.9999 and RMSECV = 3.69% and external validation with R2 = 0.9994 with RMSEP = 1.28%. The PCA results show different quadrant classifications of bovine and porcine gelatin. Also, there are similarities between the market candy quadrant, bovine gelatin, and porcine gelatin. The fast method and low cost involved simple sample preparation, which were developed to detect and classify the presence of bovine and porcine gelatin in soft candy using FTIR and chemometrics.
PENERAPAN NILAI ISLAMI DALAM PELAYANAN FARMASI KLINIS: KAJIAN SISTEMATIS ETIKA, KEHALALAN DAN KEPUASAN PASIEN Rozak, Miftahul; Saraswati, Damai Ira; Fathurohman SW, Oman; Salamah, Nina
JURNAL KAJIAN ISLAM MODERN Vol 12 No 01 (2025): MARET 2025
Publisher : Institut Agama Islam Sahid (INAIS) Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56406/jkim.v12i01.641

Abstract

Islamic pharmaceutical and healthcare services represent an innovative approach that integrates Islamic ethical values, such as justice, halal compliance, and patient satisfaction, into clinical practice. However, the application of these values faces challenges, including public knowledge gaps, insufficient training for healthcare professionals, and the lack of unified practice standards. This study employs a systematic review method to analyze relevant literature from the past decade. Literature searches were conducted using PubMed and Google Scholar with keywords such as "Islamic values in clinical pharmacy," "halal pharmaceuticals," and "maqasid shariah in healthcare." Articles meeting inclusion criteria were evaluated following PRISMA guidelines and analyzed qualitatively to identify key findings and research gaps. After the selection process, six articles met the inclusion criteria.. The findings reveal that integrating Islamic values, such as halal pharmaceuticals, Islamic ethics, and sharia-based facilities, significantly contributes to improving pharmaceutical service quality, patient satisfaction, and loyalty among Muslim patients. However, implementation remains constrained by a lack of healthcare professional training, minimal regulations, and incomplete societal perceptions. This review highlights the importance of developing an integrated framework, enhancing public and professional education, and fostering cross-professional collaboration to support the integration of Islamic values in healthcare services. This approach holds great potential to enhance service quality, patient satisfaction, and loyalty while serving as an innovative model for universal healthcare services.
A review of the halal status of ceramide in cosmetics: a strategic approach to halal policy and consumer awareness in Indonesia Basuki, Nazih; Yulianti, Rista; Fathurrohman SW, Oman; Salamah, Nina
Journal of Halal Product and Research (JHPR) Vol. 8 No. 1 (2025): Advancing the Halal Industry: Innovation, Sustainability, and Global Impact
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jhpr.vol.8-issue.1.90-100

Abstract

In cosmetics, ceramide plays a significant role in maintaining healthy skin. However, ensuring its halal status remains challenging because ceramide can be sourced from animals, plants, microbial fermentation, or chemical synthesis, each presenting its own halal-critical points. With the growing demand for halal cosmetics in Indonesia and mandatory halal certification for raw materials and finished products, special attention is required to maintain consumer trust. This study employed a literature review by analyzing registration data of ceramide-based cosmetic products from the Indonesian Food and Drug Authority (BPOM) and halal certification data from the Halal Product Assurance Organizing Agency (BPJPH). The review aimed to identify compliance gaps, examine halal policies, and understand the critical halal points in ceramide production. The analysis shows 74.52% of ceramide-based cosmetic products registered with BPOM do not have halal certification. Regulatory factors, consumer awareness, and halal raw material supply chain constraints influence this shortfall. Ceramide derived from animal sources poses the greatest challenge, whereas microbial fermentation and chemical synthesis offer greater potential for halal compliance if properly supervised. Collaboration among BPJPH, BPOM, and the Ministry of Trade is crucial to ensure compliance. Moreover, mandatory halal requirements on raw materials before the final product stage are essential to guarantee comprehensive halal assurance. Institutional synergy, public education, and improved access to halal raw materials are strategic measures to support Indonesia’s halal cosmetics industry. This study provides strategic guidance for regulators and industry players in addressing challenges related to halal regulations for ceramide-based cosmetics.   Keywords: Ceramide, Halal Cosmetics, Halal Mandatory, Halal Certification, Halal Critical Point
Authentication of Kaffir Lime Leaf Oil (Citrus hystrix D.C.) in Products Using FTIR Combined with Chemometrics Jeffry, Jeffry; Guntarti, Any; Salamah, Nina
Pharmaceutical Sciences and Research Vol. 12, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Indonesia is rich in aromatic plants, producing approximately 40 types of essential oils used in various industries, including health and aromatherapy. Essential oils have significant potential but face high rates of adulteration. This study aimed to identify kaffir lime leaf oil (Citrus hystrix D.C.), to determine the essential oil profile, and to detect adulteration in commercial oil products. The methods used involved steam distillation and characterization tests of kaffir lime leaf essential oil, including yield percentage and organoleptic, density, refractive index, and solubility in alcohol. An essential oil content test and adulteration detection using FTIR combined with chemometrics were also conducted. The FTIR results showed distinctive peaks for kaffir lime leaf oil, allowing the identification of the main compounds in the oil. Multivariate analysis using the PLS model could predict oil adulteration with RMSEC 1.319, RMSECV 1.913, and RMSEP 2.362, indicating the model’s accuracy. Furthermore, PCA successfully separated and grouped the tested oils. This study concludes that the analyzed oil was kaffir lime leaf oil, based on the characterization results and FTIR spectra showing distinctive peaks of the oil. PLS and PCA analysis showed that the three tested commercial oil products did not contain turpentine adulterants.
Analysis of Hydrolyzed Collagen in Facial Serum for Halal Authentication Using FTIR Spectroscopy and Multivariate Calibration Salamah, Nina; Firdaus, Rizqi Amalia; Guntarti, Any; Ahda, Mustofa; Uddin, Abm Helal; Kurniawan, Muhammad Fariez
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1270-1279

Abstract

Cosmetic trends in Indonesia are on the rise, particularly for facial serum products. However, most of these products lack halal certification, posing an important concern for Muslim consumers due to the potential use of haram substances, such as pork gelatin. This study seeks to identify the source of gelatin in serum products using the Fourier Transform Infrared (FTIR) spectroscopy and chemometric analysis. The samples used in this study include a reference facial serum formulated with pure bovine and porcine gelatin concentrations in the ratios of 1:0, 8:2, 5:5, 2:8, and 0:1, three hydrolyzed collagen serums that are not yet labeled halal and available on Shopee, and one serum that is labeled halal. The method used was FTIR combined with PLS chemometrics and PCA. The isolation of facial serum gelatin was performed using acetone at -20oC, followed by analysis via FTIR at wave numbers ranging from 4000 to 400 cm-1. FTIR results indicated the presence of functional groups in gelatin constituents, including C O, N H, C N, and C H aliphatic. The wavelengths employed for PLS and PCA analysis ranged from 1631 to 1430 cm-1. Calibration results showed R2=0.9936 and RMSEC=3.0445%. Internal validation yielded RMSECV=0.1674% and R2=0.9994 whilst external validation yielded RMSEP=0.9981% and R2=0.9910. Lastly, PCA analysis revealed that one halal-labeled serum sample contained bovine gelatin, whereas the three examined commercial serums were free from both pork and bovine gelatin.
EFEK EKSTRAK ETANOL GANGGANG HIJAU (Ulva lactuca , L) TERHADAP EKSPRESI COX-2 MIOKARDIUM TIKUS YANG DIINDUKSI ISOPROTERENOL Widyaningsih, Wahyu; Salamah, Nina; Pramono, Suwidjiyo; Sugiyanto, Sugiyanto; Widyarini, Sitarina
Media Farmasi: Jurnal Ilmu Farmasi Vol. 16 No. 2: September 2019
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v16i2.12822

Abstract

Penyakit kardiovaskuler masih merupakan masalah di Indonesia salah satunya adalah Infark Miokardial Akut (IMA). Patofisiologis AMI karena rective oxigen spesies  (ROS) melibatkan stimulasi sitokin pro inflamasi salah satunya adalah  interleukin-1 yang berakibat peningkatan ekspresi COX-2. Penelitian ini bertujuan mengetahui efek ekstrak etanol ganggang hijau dalam menurunkan ekspresi COX-2 pada tikus IMA yang diinduksi isoproterenol (ISO). Ekstraksi ganggang hijau dengan maserasi menggunakan etanol 96%. Tikus berat 200-250 g dibagi menjadi 6 kelompok masing-masing 6 ekor. Kelompok I kontrol, tikus tidak diberi ISO hanya diberi CMC Na, kelompok II kelompok ISO, tikus diberi CMC Na dan ISO, kelompok III, IV dan V tikus diberi ekstrak etanol ganggang hijau dosis 250, 500 dan 750 mg/KgBB peroral dan kelompok VI diberi melatonin 10 mg/KgBB. Perlakuan ekstrak selama 28 hari. Pada hari ke 29 dan 30 tikus diberi isoproterenol dosis 85 mg/KgBB selama 2 kali pemberian secara subkutan kecuali kelompok I. Pada hari ke 31 tikus diambil organ jantung kemudian dibuat preparat histologis dan dilakukan analisis ekspresi COX-2 dengan metode imunohistokimia dengan antibodi anti COX-2. Hasil penelitian menunjukkan bahwa pemberian ekstrak etanol ganggang hijau dosis 250, 500 dan 750 mg/KgBB dapat menurunkan ekspresi COX-2 pada tikus yang diinduksi isoproterenol.
Analisis Profil Minyak Atsiri Daun Kayu Putih (Melaleuca leucadendra L.) dan Produk di Pasaran Irfan, Nawwar; Nurani, Laela Hayu; Guntarti, Any; Salamah, Nina; Edityaningrum, Citra Ariani
Journal of Food and Pharmaceutical Sciences Vol 10, No 3 (2022): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.5785

Abstract

Minyak kayu putih merupakan salah satu minyak atsiri yang biasa digunakan dalam sehari-hari. Produksi dalam negeri hanya dapat memproduksi minyak kayu putih 650 ton/tahun dari permintaan kebutuhan dalam negeri dalam setahun sebesar 3.500 ton sehingga memacu pemalsuan. Penelitian ini bertujuan untuk membandingkan profil minyak kayu putih hasil destilasi dengan minyak kayu putih yang ada di pasaran berdasarkan mutu Standar Nasional Indonesia (SNI). Destilasi minyak atsiri dilakukan dengan 5 kg daun kayu putih menggunakan metode destilasi uap air selama 3 hari didapatkan rendemen sebesar 2,32%. Minyak kayu putih hasil destilasi dan minyak produk A, B dan C dilakukan pengujian profil minyak berdasarkan SNI 06-3954-2006 meliputi warna, bau, bobot jenis, indeks bias, kelarutan dalam etanol 70%, dan profil KLT. Hasil pengamatan organoleptis minyak hasil destilasi, produk A, B, dan C memiliki perbedaan warna, bobot jenis, dan kelarutan dalam etanol 70% serta tidak ada perbedaan bau dan indeks bias. Hasil penelitian menunjukkan adanya perbedaan profil minyak produk A, B, dan C yang tidak memenuhi SNI pada pengujian bobot jenis pada produk C. KLT dengan menggunakan fase diam silika gel GF254 dan fase gerak Toluen (100%). Profil KLT pada produk C tidak terlihat noda yang sama dengan standar eucalyptol yang diperlihatkan oleh minyak lainnya. Keywords: Analisis profil, Minyak kayu putih, SNI 06-3954-2006
Analysis of Physicochemical Properties and Quality Testing of Beef Tallow and Lard Oil Along with Identification using FTIR and GC-MS Mukti Utomo, Adhitya Ilham; Salamah, Nina; Guntarti, Any; Ahda, Mustofa
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.21973

Abstract

The halal industry is rapidly growing worldwide, especially in Indonesia, which has the largest Muslim population and abundant natural resources. This study aims to analyze the physicochemical properties and quality of beef tallow and lard oil, as well as to identify differences in FTIR and GC-MS spectra to distinguish between these two animal fats.The results show that lard oil has a higher extraction yield (30%) compared to beef tallow (17%). Lard oil also has a higher iodine value (53 g), indicating a greater proportion of unsaturated fatty acids, making it suitable for culinary applications. Conversely, beef tallow has a lower peroxide value (5 meq O₂/kg), indicating better resistance to oxidation.FTIR analysis reveals differences in functional groups, with lard oil showing a higher degree of unsaturation. GC-MS analysis identifies important compounds such as 9-octadecenoic acid methyl ester in lard oil, while beef tallow is dominated by tetradecanoic acid methyl ester.This study emphasizes the need for the development of Indonesian National Standards (SNI) to ensure product quality and halal compliance. These findings provide important insights for the halal industry and food safety in Indonesia, as well as encouraging further research on the composition of animal fats.
Analisis Gelatin pada Soft Candy Produk Dalam Negeri Menggunakan Fourier Transform Infrared (FTIR) dengan Kombinasi Kemometrika Salamah, Nina; Fatmawati, Arum; Guntarti, Any
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1486

Abstract

Gelatin is widely used in the food industry, including soft candy. It is generally sourced from cows and pigs. However, adding porcine gelatin to food will be problematic for the Muslim community due to its prohibition in their beliefs. Therefore, the soft candy’s components should be analysed to determine whether the functional groups are of bovine or porcine gelatin. From three local soft candy products in Indonesia, gelatin was isolated with acetone by vortexing and centrifugation. The supernatant was analysed with FTIR to determine its spectral profile. Furthermore, the wavenumbers and absorbances of gelatin’s functional groups were analysed in Minitab 18 with multivariate PLS and PCA. FTIR showed that gelatin contained proteins with O-H, aliphatic C-H, C=O, N-H, and C-N groups. PLS and PCA were conducted in the wavenumber range of 1576–1481 cm-1. The calibration yielded R2 = 0.9997 and RMSEC = 0.9376%. The internal validation showed R2 = 0.9998 and RMSECV = 1.29%, while the external validation produced R2 = 0.9996 and RMSEP = 1.04%. Clustering with PCA revealed that the gelatin sample from one soft candy was in the same quadrant as the reference bovine gelatin, while the other two were in different quadrants from both references.
Co-Authors A Riyanto Abdul Rohman Agustin LN Aminin Ajeng Dian Pertiwi, Ajeng Dian Anggita Devi Anita Wening Sejati Anjani, Ratna Annta Kern Nugrohowati Any Guntarti Any Guntarti Any Guntarti Any Guntarti Any Guntarti Ar Rahma, Nur Aulia Banundari Rachmawati Barokati Azizah Basuki, Nazih Citra Ariani Edityaningrum, Citra Citra Dhea Cantika Danang Prasetyaning Amukti Desti Kameliani Dwi Fitriani Erlinda Widyasari Fathurohman SW, Oman Fathurrohman SW, Oman FATMAWATI, ARUM Fella Qulsum Maulida Firdaus, Rizqi Amalia Gunawan Anugra Sumule, Joshua Hari Susanti Hayati, Farida Hikmah, Nazila Nur Ikawati, Retty INNAYAH IZATI Irfan, Nawwar Jaswir, Irwandi Jufri, Sayyidah Luthfiyah Justitia Cahyani Fadli Juwitaningtyas, Titisari Kasmawati, Henny Kurniaty, Santyas Kurniawan, Muhammad Fariez Laela Hayu Nurani Liani Farahana Ma'ruf, Muhammad Mae Sri Hartati Wahyuningsih Mahendra, Muhammad Reza Miftahul Rozak Mohamed, Farahidah Muhammad Sulkhan Muhti Al Abror Mukti Utomo, Adhitya Ilham Mustofa Ahda Nanik Sulistyani Nining Sugihartini Novitasari, Putri Rachma Nurkhasanah Mahfudh Pangaribuan, Ika S Pinus Jumariyatno Pora, Yohana Laura Silfia Pradini, Ni Komang Virginia Rina Handayani Rosyida Awalia Safitri Rozak, Miftahul Saraswati, Damai Ira SATRIYAS ILYAS Sembiring, Rinawati Sihaloho, Serli Sitarina Widyarini Siti Athiyah Umaiyah Siti Fatimah Sultan Sudibyo Martono Sudibyo Martono Sugiyanto - Sugiyanto . Sugiyanto . Sugiyanto Sugiyanto Sugiyanto Sugiyanto Sultan, Siti Fatimah Sunarti Sunarti Suwidjiyo Pramono Suwidjiyo Pramono SW, Oman Fathurohman Uddin, ABM Helal Verda Farida Wahyu Widyaningsih Wahyu Widyaningsih Wahyu Widyaningsih Wahyu Widyaningsih Wahyuningtyas, Nurma Widi Astuti, Silvia Ferry WULANDARI Yamin Yulianti, Rista Yuny Erwanto Yuny Erwanto Zahra Alya Putri