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All Journal International Journal of Public Health Science (IJPHS) Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Science and Technology Indonesia Ilmu Gizi Indonesia Indonesian Journal of Chemistry JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical Journal of Indonesia Jurnal Mandala Pharmacon Indonesia Indonesian Journal of Halal Research Jurnal Ilmiah Farmako Bahari Journal of halal product and research (JHPR) Lumbung Farmasi : Jurnal Ilmu Kefarmasian Community Empowerment Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Jurnal Kajian Islam Modern Journal of Halal Science and Research Journal of Pharmaceutical and Sciences. Riwayat: Educational Journal of History and Humanities Journal of Food and Pharmaceutical Sciences Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmacy and Halal Studies (JPHS)
Nina Salamah
Fakultas Farmasi, Universitas Ahmad Dahlan
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Analysis of the theory of planned behavior on the use of halal-labeled cosmetics for students at the University of Islamic Malang Ma'ruf, Muhammad; Salamah, Nina
Journal of Halal Science and Research Vol. 4 No. 2 (2023): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v4i2.7122

Abstract

The practice of using halal cosmetics involves the intentional involvement of individuals, groups, or organizations in acquiring and using cosmetics that have obtained a halal certification. The behavior of individuals is subject to influence by multiple factors, including attitudes, subjective norms, behavioral control, and intention to use. These factors are motivated by the desires and needs of the individual. This study examines the influence of attitudes, subjective norms, behavioral control, and usage intentions on adopting halal-labeled cosmetics among college students. This research investigates the impact of attitudes, subjective norms, behavioral management, and usage intentions on adopting cosmetics labeled as "halal" among college students. The study employs online surveys as the primary method for data collection. The research utilized a purposive sampling methodology to select a sample size of 110 participants. The present study utilizes a data analysis technique that involves applying multiple regression analysis using the SPSS 25.0 software. The results of this study indicate that the variables of attitude, behavioral control, and intention to use have a statistically significant impact on the utilization of halal-certified cosmetic products. On the other hand, the influence of subjective norms on the utilization of halal decorative goods among students enrolled in the Faculty of Mathematics and Natural Sciences at the University of Islamic Malang is determined to have no significant statistical effect. Keywords: Halal, Cosmetics, Students, Theory of Planned Behavior.
Concentration of isolated DNA face masks made of gelatin for halal authentication Hikmah, Nazila Nur; Guntarti, Any; Salamah, Nina
Journal of Halal Science and Research Vol. 5 No. 1 (2024): February
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v5i1.8951

Abstract

The function of using a face mask is to remove dirt and dead skin cells found in the pores of the skin, open clogged pores and clean the remaining cosmetics that cannot remove with ordinary cleansers, repair and tighten the skin, provide nutrition, smooth, soften and maintain skin moisture. People are aware of halal-labeled cosmetics, one of which is face masks because some face masks contain gelatin. Some face masks on the market contain gelatin. Preparation of 5 reference samples with different concentrations. Preparation of face masks, DNA isolation, and checking the isolation results. The test results with the Nanodrop Spectrophotometer showed that the face mask DNA containing pig and cow gelatin extracted in this study ranged from 163.35 ng/µl in sample S6 to 83.550 ng/µl in sample S7. With the largest concentrations of 163.35 ng/µl and 83.550 ng/µl, while the highest purity value at the λ260/λ280 ratio was 1.41.
Development of ethanol analysis in cough syrup medicine by colorimetric method Sultan, Siti Fatimah; Susanti, Hari; Mohamed, Farahidah; Salamah, Nina; Farida, Verda
Journal of Halal Science and Research Vol. 6 No. 1 (2025): February
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v6i1.12217

Abstract

Cough syrup is a pharmaceutical preparation often containing ethanol as a solvent. However, the presence of ethanol in the drug can cause safety issues. This study aims to develop and validate a colorimetric method for determining ethanol in cough syrup. Cough syrup samples from different brands were analyzed using the method. The Visible spectrophotometric method uses the oxidation reaction of ethanol with potassium dichromate in an acidic condition. Method validation was conducted, including linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ). The results showed this method had good linearity (r > 0.99) with a concentration range of 0.48 – 5.76 % (b/v). UV-Vis spectrophotometric method showed good precision and accuracy with SD = 0.0014, RSD = 0.4046 %, and % recovery = 99.99 %, while LOD = 0.1074 % and LOQ = 0.3253 %. This study concludes that the colorimetric method can be used as a valid and complementary method for analyzing ethanol content in cough syrup, providing important information for producers and consumers regarding product safety.   Keywords: Analytical method validation, Cough syrup, Ethanol, Spectrophotometry.
Antioxidant Activity of Facial Gel Moisturizer Formulation From Various Plants: A Literature Review adhitya ilham mukti; karunia nining handaningrum; Rini rahmawati; Nina Salamah
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol. 22 No. 2 (2025): Jurnal Ilmu Farmasi dan Farmasi Klinis
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v22i2.12398

Abstract

Antioxidants are compounds that can neutralize free radicals, which can damage normal cells, fats, and proteins. Various methods, such as DPPH, ABTS, and FRAP, are used to evaluate the capacity of antioxidant compounds against reactive oxygen species (ROS). Skin ageing, caused by free radicals, pollution, and ultraviolet rays, can be mitigated by using antioxidants, one of which is found in cosmetic preparations such as moisturizers. This study aims to determine the antioxidant activity of various plant extracts in the formulation of a moisturizer gel. The method used is a literature review, with sources from the Google Scholar and PubMed databases, which includes articles from 2014 to 2024, resulting in 9 eligible articles out of 20 screened. The review result showed that plants such as star fruit leaf extract (Averrhoa bilimbi L.) and green tea leaf (Camellia sinensis) have potent antioxidant activity. Starfruit Wuluh (Averrhoa bilimbi L.) extracted with 70% ethanol had an IC50 value of 24.78 ppm, while green tea leaf extract (Camellia sinensis) with 70% ethanol showed an IC50 value of 5.62 ppm in the gel moisturizer preparation. A high IC50 indicates that the compound contains antioxidants that can protect the skin from free radicals, which are formulated into a moisturizing gel. In conclusion, star fruit leaf extract (Averrhoa bilimbi L.) and green tea leaf extract (Camellia sinensis) are highly effective ingredients in moisturiser gel products, as they provide significant antioxidant protection to the ski  
Formulation Optimization and Antibacterial Activity of Citronella (Cymbopogon nardus (L.) Rendle) Topical Gel Spray Against Staphylococcus aureus Using a Simplex Lattice Design Rajab, Muhammad Andy; Putri, Chintiana Nindya; Suryani, Arman; Salamah, Nina
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.867

Abstract

Atopic dermatitis is skin inflammation in the form of dermatitis caused by Staphylococcus aureus bacterial infection. Citronella essential oil has the potential as an active ingredient in spray gel preparations to help overcome atopic dermatitis due to Staphylococcus aureus bacterial infection. The aim is to determine the optimal spray gel formula from citronella essential oil (Cymbopogon nardus (L.) Rendle) and antibacterial activity against Staphylococcus aureus bacteria. The methods material optimized are Na-CMC, Propylene glycol, and tween 20. Evaluation of the preparation in the form of organoleptic tests, homogeneity, pH, viscosity, drying time, spraying patterns, yeast mold numbers using the spread plate method, and antibacterial activity against Staphylococcus aureus bacteria using the good diffusion method. The results of the concentration of Na-CMC: Propylene glycol: Tween 20 (0.27: 4.72: 10) produced an optimal preparation formula. The spray gel is milky white, has a distinctive lemongrass odor, and is slightly thick. The spray gel is homogeneous with a pH of 4.94 ± 0.16, a viscosity of 76.73 ± 7.01 cPs, and a drying time of 3.60 ± 0.40 minutes. The mold/yeast count test showed that the spray gel was free from mold/yeast contamination and was stable at storage temperatures of 4?C and 40?C. The results of antibacterial activity were able to inhibit Staphylococcus aureus bacteria with an inhibition zone diameter of 6.85 mm ± 2.80. Conclusion: Na-CMC concentration of 0.27%, Propylene Glycol concentration of 4.72%, and Tween 20 concentration of 10% produced optimal spray gel and inhibited Staphylococcus aureus.
Analysis of Gelatin on Soft Candy using a Combination of Fourier Transform Infrared Spectroscopy (FTIR) with Chemometrics for Halal Authentication Salamah, Nina; Jufri, Sayyidah Luthfiyah; Susanti, Hari; Jaswir, Irwandi
Indonesian Journal of Halal Research Vol. 5 No. 2 (2023): August
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ijhar.v5i2.25682

Abstract

The main ingredients of soft candies are gelatin made from the skin/bones of cows and pigs, i.e. bovine and porcine gelatin. This research aims to analyze the present bovine and porcine gelatin in soft candy using a fast and low-cost method. The method used is a combination of FTIR and chemometrics. The reference candy samples were made with formulation porcine gelatin concentrations of 15, 30, 45, 60, 75, 90 and 100%. As a control, we used a bovine gelatin reference candy. All the candy samples were measured with FTIR in the reflection mode in the wavenumber range from 4000 to 500 cm-1. Data analysis was carried out using the chemometric method with the Minitab 18 application. PLS calibration results in y = 0, 99999x + 0.000396 indicate a good correlation. The value of R2 = 0.99999 and the RMSEC of 0.03%. Internal validation with R2 = 0.9999 and RMSECV = 3.69% and external validation with R2 = 0.9994 with RMSEP = 1.28%. The PCA results show different quadrant classifications of bovine and porcine gelatin. Also, there are similarities between the market candy quadrant, bovine gelatin, and porcine gelatin. The fast method and low cost involved simple sample preparation, which were developed to detect and classify the presence of bovine and porcine gelatin in soft candy using FTIR and chemometrics.
Acute Toxicity Test of Healthy Drink of Anthocyanin Pigmented Polyphenols from Black Rice and Sprouts Soybean Kintoko, Kintoko; Salamah, Nina; Witasari, Hardi Astuti; Maulizah, Rizlah
Journal of Food and Pharmaceutical Sciences Vol 14, No 2 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.25784

Abstract

Black rice and sprouted soybean (BRiSS) can be formulated into a healthy drink BRiSS. The safety of this novel combination must be rigorously tested. Therefore, this study was designed to conduct a comprehensive acute toxicity test of the healthy drink flavylium anthocyanins from black rice (Oryza sativa L. indica) pigmented polyphenols from soybean sprouts (Glycine max L.). The black rice was extracted with a 96% ethanol solution in 3% citric acid. The pigmentation process was achieved by adding hydroxyl groups from soybean polyphenols. The active material was mixed with 20% maltodextrin, shaken, poured into a pan, and dried with a cabinet dryer (60° C). The mixture was stirred with 0.3% sodium, 0.1% citric acid, 50% active ingredients, 5% sucrose as a sweetener, 0.05% sodium benzoate, and water, 100 ml. The five groups of male Wistar rats were acclimatized. Group 1 was a control, and groups 2, 3, 4, and 5 were sequentially treated with a healthy drink containing extract doses of 5, 50, 300, and 2000 mg/kg BW. The acute toxicity test results at 30 minutes, 3 to 24 hours, day 3, and day 14 were written on the acute toxicity test clinical symptom observation sheet. All test animals, including both the control and test groups with various dosage variations, did not exhibit changes in skin, fur, eyes, behavior, respiratory systems, and did not experience weight loss, seizures, tremors, lethargy, or diarrhea. The limitation was that the macropathology examination of internal organs (kidneys, liver, heart, brain, stomach, intestines, pancreas) was not performed. Not all animals have mortality in a 5-3000 (mg/kg BW) extract dose.
Acute Toxicity Test of Black Rice and Soybean Extract Complex Liza Syafitri; Nina Salamah; Ichwan Ridwan Rais; Kintoko Kintoko; Sri Mulyaningsih; Moch Saiful Bachri
Jurnal Ilmiah Farmako Bahari Vol 17 No 2 (2026): Jurnal Ilmiah Farmako Bahari
Publisher : Faculty of Mathematic and Natural Science, Garut University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52434/jifb.v17i2.43524

Abstract

The present study was conducted to assess the acute oral toxicity of a copigment complex formulated from extracts of black rice (Oryza sativa L., indica) and soybean (Glycine max (L.) Merr.). Despite extensive individual pharmacological investigations of these botanical sources, no safety data have previously been documented for their combined copigment complex intended as a functional beverage constituent. Following the Acute Toxic Class methodology (OECD 423), the complex was orally administered as a single dose at 300, 2000, or 5000 mg/kg body weight (BW) to female Swiss Webster mice (n=3 per dose group), alongside a vehicle control group administered 1% Na-CMC. A comprehensive 14-day monitoring program assessed mortality, a range of clinical indicators (including tremor, convulsions, salivation, diarrhea, lethargy, locomotion, coat condition, and ocular appearance), and body weight at Days 0, 7, and 14. No animal deaths occurred across any group. Transient, mild hypoactivity was noted in animals receiving 5000 mg/kg at 1–2 hours post-dose, which resolved completely by 4 hours post-administration. No additional adverse clinical manifestations or weight loss were detected. Based on these findings, the median lethal dose (LD50) is projected to surpass 5000 mg/kg BW, corresponding to GHS Category 5 (practically non-toxic). The results collectively establish a safety foundation for the use of this copigment complex as a functional ingredient in isotonic beverage products, while acknowledging the need for further subchronic and chronic toxicological investigations.
Potensi Famili Zingiberaceae Sebagai Terapi Kanker Payudara : Review Aulia Syafadilla Azali; Arini Salsabila; Muhammad Andy Rajab; Moch Saiful Bachri; Dian Prasasti; Nina Salamah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 2 (2026): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i2.39641

Abstract

Kanker payudara merupakan penyebab utama kematian pada perempuan secara global, termasuk di Indonesia. Meskipun terapi konvensional seperti kemoterapi dan terapi target telah digunakan secara luas, efektivitasnya masih terbatas dan sering menimbulkan efek samping serius. Dalam konteks ini, pemanfaatan tanaman obat mulai menjadi perhatian karena potensi bioaktifnya dan harapan untuk menghadirkan pilihan terapi yang lebih aman serta terjangkau. Kajian ini bertujuan mengidentifikasi dan memahami bukti ilmiah terkini mengenai potensi antikanker tanaman dalam famili Zingiberaceae terhadap kanker payudara serta mekanisme molekuler yang mendasarinya. Artikel ini merupakan narrative review terhadap 18 literatur ilmiah dari basis data PubMed, Scopus, ScienceDirect, dan Google Scholar yang membahas efek antikanker tanaman Zingiberaceae pada sel kanker payudara tipe luminal (MCF-7 dan T47D) serta triple-negative (MDA-MB-231 dan 4T1). Hasil kajian menunjukkan bahwa tanaman famili Zingiberaceae berpotensi sebagai sumber kandidat agen antikanker payudara melalui berbagai mekanisme molekuler. Aktivitas antikanker ditunjukkan oleh nilai IC₅₀ yang bervariasi antarspesies, mencerminkan perbedaan potensi sitotoksik. Di antara seluruh spesies yang dikaji, Boesenbergia rotunda menunjukkan potensi paling kuat dengan nilai IC₅₀ sebesar 5,62 µg/mL. Selain itu, diperlukan standardisasi metode ekstraksi, karakterisasi senyawa aktif, dan parameter pengujian untuk meningkatkan konsistensi hasil penelitian serta memperkuat bukti ilmiah terkait potensi famili Zingiberaceae sebagai sumber kandidat agen antikanker payudara.
Uji Efektivitas Antibakteri Ekstrak Etanol Daun Jeruk Nipis (Citrus aurantifolia) Terhadap Bakteri Shigella dysentriae Ria Indah Pratami; Silmi Kaffah; Danang Prasetyaning Amukti; Nina Salamah; Sitti Masyithah Awaluddin; Achmad Wahyudi; Asih Fatriansari
Journal of Pharmacy and Halal Studies Vol. 2 No. 1 (2024): Journal of Pharmacy and Halal Studies (JPHS)
Publisher : Edu Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70608/x3v86k38

Abstract

Penyakit Infeksi merupakan masalah kesehatan masyarakat yang sangat penting untuk diperhatikan khususnya di negara berkembang, dengan banyaknya kasus yang terjadi di Indonesia adalah diare. Daun jeruk nipis (Citrus aurantifolia) merupakan tanaman populer yang dikenal karena sifat antibakteri, antimikroba, antijamur, dan antiparasitnya. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol daun jeruk nipis terhadap bakteri Shigella dysentriae menggunakan metode difusi cakram. Hasil penelitian menunjukkan bahwa ekstrak etanol daun jeruk nipis dapat menghambat pertumbuhan bakteri Shigella dysentriae pada konsentrasi 10% dengan diameter 20,53 mm. Penelitian ini menemukan perbedaan yang signifikan pada konsentrasi ekstrak etanol yang menunjukkan bahwa ekstrak daun jeruk nipis efektif dalam menghambat bakteri Shigella dysentriae.
Co-Authors A Riyanto Abdul Rohman Achmad Wahyudi adhitya ilham mukti Agustin LN Aminin Ajeng Dian Pertiwi, Ajeng Dian Anggita Devi Anisa Firdaus Anita Wening Sejati Anjani, Ratna Annta Kern Nugrohowati Any Guntarti Any Guntarti Any Guntarti Any Guntarti Any Guntarti Ar Rahma, Nur Aulia Arini Salsabila Aulia Syafadilla Azali Banundari Rachmawati Barokati Azizah Basuki, Nazih Citra Ariani Edityaningrum, Citra Citra Dhea Cantika Danang Prasetyaning Amukti Desti Kameliani Dian Prasasti Dwi Fitriani Erlinda Widyasari Fathurohman SW, Oman Fathurrohman SW, Oman FATMAWATI, ARUM Fatriansari, Asih Fella Qulsum Maulida Firdaus, Rizqi Amalia Gunawan Anugra Sumule, Joshua Hardi Astuti Witasari Hari Susanti Hayati, Farida Hikmah, Nazila Nur Ichwan Ridwan Rais Ikawati, Retty INNAYAH IZATI Irfan, Nawwar Jaswir, Irwandi Jufri, Sayyidah Luthfiyah Justitia Cahyani Fadli karunia nining handaningrum Kasmawati, Henny Kintoko Kintoko Kintoko, Kintoko Kurniaty, Santyas Kurniawan, Muhammad Fariez Laela Hayu Nurani Liani Farahana Liza Syafitri Ma'ruf, Muhammad Mae Sri Hartati Wahyuningsih Mahendra, Muhammad Reza Maulizah, Rizlah Miftahul Rozak Moch Saiful Bachri Mohamed, Farahidah Muhammad Andy Rajab Muhammad Sulkhan Muhti Al Abror Mukti Utomo, Adhitya Ilham Mustofa Ahda Nanik Sulistyani Ni Komang Virginia Pradini Nining Sugihartini Novita Diana Ayu Candra Nurkhasanah Mahfudh Nurkhasanah Nurkhasanah Pangaribuan, Ika S Pinus Jumariyatno Pora, Yohana Laura Silfia Pradini, Ni Komang Virginia Prasti Andini Putri, Chintiana Nindya Rajab, Muhammad Andy Ria Indah Pratami Rina Handayani Rini Rahmawati Rosyida Awalia Safitri Rozak, Miftahul Saraswati, Damai Ira SATRIYAS ILYAS Sembiring, Rinawati Sihaloho, Serli Silmi Kaffah Sitarina Widyarini Siti Athiyah Umaiyah Siti Fatimah Sultan Sitti Masyithah Awaluddin Sri Mulyaningisih Sri Mulyaningsih Sudibyo Martono Sudibyo Martono Sugiyanto - Sugiyanto . Sugiyanto . Sugiyanto Sugiyanto Sugiyanto Sugiyanto Sunarti Sunarti Suryani, Arman Suwidjiyo Pramono Suwidjiyo Pramono SW, Oman Fathurohman Syafitri, Liza Uddin, ABM Helal Verda Farida Wahyu Widyaningsih Wahyu Widyaningsih Wahyu Widyaningsih Wahyu Widyaningsih Wahyuningtyas, Nurma Widi Astuti, Silvia Ferry WULANDARI Yamin Yulianti, Rista Yuny Erwanto Yuny Erwanto Zahra Alya Putri