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All Journal Majalah Kedokteran Bandung BERITA BIOLOGI Jurnal Penelitian Kesehatan Suara Forikes Media Ilmu Kesehatan JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmasi Indonesia Jurnal Mandala Pharmacon Indonesia Health Information : Jurnal Penelitian Jurnal Kefarmasian AKFARINDO Science Midwifery Indonesian Journal of Global Health research Infokes : Jurnal Ilmiah Rekam Medis dan Informasi Kesehatan Jurnal Ilmiah Kesehatan (JIKA) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Multidisiplin Madani (MUDIMA) Formosa Journal of Multidisciplinary Research (FJMR) Jurnal Farmasi Sains dan Praktis Jurnal Kesehatan Tropis Indonesia Journal of Health Management and Pharmacy Exploration (JOHMPE) International Journal of Global Sustainable Research Jurnal Sains dan Kesehatan Strada Jurnal Ilmiah Kesehatan (SJIK)
Opstaria saptarini
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Journal : Jurnal Ilmiah Kesehatan (JIKA)

 1 
Effect of Ethanol Extract and Fractions of Saluang Balum Root Lavanga Sarmentosa (Blume) Kurz) on Aphrodisiac Activity and Spermatogenesis in Hyperglicemia Rats Dwiannur, Febriandi Ramadhan; Peranginangin, Jason Merari; Saptarini, Opstaria
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 2 (2024): Volume 6 Nomor 2 Agustus 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i2.848

Abstract

High blood glucose levels or hyperglycemia can increase reactive oxygen species (ROS). Complications of secondary diabetes mellitus in the form of sexual dysfunction and impaired fertility in men. This is one of the causes of decreased sexual desire and sperm count, which can cause infertility in men. Saluang balum root (Lavanga sarmentosa (Blume) Kurz) with flavonoid, steroid, and tannin compounds is a traditional medicine that has the potential as an aphrodisiac and spermatogenesis. The purpose of this study was to obtain a histological picture of the seminiferous tubules, a decrease in blood glucose levels, aphrodisiac activity, and spermatogenesis. This study used 35 male wistar rats which were divided into 7 groups, normal group, negative control (CMC Na 1%), positive control (pasak bumi), ethanol extract of saluang balum root at a dose of (225 mg/kgBW), n-hexane fraction. (19.81 mg/kgBW), ethyl acetate fraction (64.5 mg/kgBW) and water fraction (140.67 mg/kgBW). All of these groups were induced by alloxan (100 mg/kgBW), except the normal group. The extracts and fractions were given for 14 days, then observed a decrease in blood glucose levels, aphrodisiacs, spermatogenesis and histological features in the seminiferous tubules. The results showed that the extract and fractions of saluang balum root had reduced blood glucose levels, aphrodisiac and spermatogenesis in hyperglycemic rats.
Co-Authors Andintias, Mohammad Febry Aulia, Intan Sofia Irsa Claudius Hendraman B. Tobi Daniel Happy Putra Dewi Natalia Dinda Sri Rahayu Dwiannur, Febriandi Ramadhan Embu, Yohanes Dwi Putra Agung Endang Sri Rejeki Faelga Sara Fradine, Chossy Fransiska Leviana Gunawan P Widodo Gunawan Pamudji Ibnu Nugroho Saputra Ika Purwidyaningrum Ilham Kuncahyo, Ilham Inaratul Rizkhy Hanifah Ismi Rahmawati Ismi Rahmawati Ismi Rahmawati Ismi Rahmawati Jason Merari Peranginangin Kartiwi, Wiwi Khairunnisa, Rizky Dila Kurniasari, Fitri Lina Susanti Mariyo Jane Sanggel Muhammad Alviyan Shutiawan Munawi Munawir Munawir Munawir Mustika Endah Pratiwi Najiyyah, Trias Durrotun Nia Azzahra Nurul Rafiqua Pamudji, Gunawan Perawati Perdina Nursidika Pranata, Yovi Priska Juanita Pakingki Putri, Luluk Aniqoh Meliana R.A. Oetari, R.A. RA Oetari Rahayu, Dinda Sri Rahmawati, Ismi Rakhmi Hidayati Sabda Wahab santi dwi astuti Suhartinah Suhartinah Suherman, Sri Devi Nur Rahma Sunarni , Titik Syahputra, Rizka Wahyu Titik Sunarni Titik Sunarni Tri Wijayanti Tri Wijayanti Tria Yuganingsih Veronica Bella Lupita Wiwin Herdwiani Yerri Hartanto Yohanes Dwi Putra Agung Embu