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Prevalensi Parasit Soil Transmitted Helminths Pada Anak Usia 2-9 Tahun Di Rukun Warga 04 Kelurahan Batakte Kecamatan Kupang Barat Kabupaten Kupang Tahun 2017 Ni Made Susilawati; Rini Kurniaty Smaut
JURNAL INFO KESEHATAN Vol 15 No 1 (2017): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

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Abstract

Infection worm is one of the many diseases that occur in the community but less attention. This can be due to the worm group Soil-Transmitted Helminths (STH), a group of worms that cycle through the soil life, namely Ascaris lumbricoides, Trichuris trichiura, Strongyloides stercoralis, Necator americanus and Ancylostoma sp. Children more often found STH infected. The purpose of this study is to determine the prevalence of STH parasites in children aged 2-9 years in RW 04 Batakte Urban Village, Kupang Barat District, Kupang District in 2017. This type of research is a descriptive research that is the prevalence of Soil-Transmitted Helminths parasite. The subjects of this study were 59 children collected by total sampling method. The feces of the study subjects were collected, then examined by the native method to determine STH infection. The result of the research that has been done, the prevalence of Soil-Transmitted Helminths parasite in children aged 2-9 years in RW 04 Batakte urban village is 12% is 7 samples positive Ascaris lumbricoides (Ascariasis).
Evaluasi Kadar Glukosa Darah Pada Pasien Hipertensi yang Menggunakan Obat Golongan Angiostensin Receptor Bloker (ARB) di Rumah Sakit Umum Daerah Undata Palu Susilawati, Ni Made; Fresha, Winda; Rumi, Amelia; Adisaputra, Arya Dibyo
Herbal Medicine Journal Vol 8 No 1 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i1.151

Abstract

Hipertensi adalah kondisi medis yang ditandai dengan peningkatan tekanan darah arteri secara berkelanjutan. Salah satu golongan obat lini pertama pengobatan hipertensi adalah golongan Angiotensin Receptor Blocker (ARB). Obat ini berpotensi dapat dapat mempengaruhi metabolisme glukosa darah. Penelitian ini bertujuan untuk mengevaluasi kadar glukosa darah pada pasien hipertensi yang menjalani terapi menggunakan obat ARB, seperti losartan, candesartan, valsartan, dan telmisartan, di RSUD Undata Palu. Penelitian ini dilakukan dengan metode cross-sectional secara prospektif, melibatkan 30 pasien yang memenuhi kriteria inklusi. Pasien yang diteliti berusia ≥18 tahun, telah menjalani terapi ARB selama 3 bulan, memiliki hipertensi tanpa diabetes melitus, dan tidak menggunakan obat lain yang memengaruhi kadar glukosa darah. Pengukuran dilakukan menggunakan glucometer Accu-Chek Performa. Hasilnya menunjukkan penurunan kadar glukosa darah puasa dari rata-rata 113.83 mg/dl menjadi 107.83 mg/dl, dengan selisih 6.367 mg/dl. Uji statistik menunjukkan p=0.049 (p<0.05), yang mengindikasikan bahwa ARB dapat menurunkan kadar glukosa darah pada pasien hipertensi.
EFEK PENGGUNAAN BETA BLOCKER TERHADAP KEJADIAN HIPOGLIKEMIA PADA LANSIA: NARRATIVE REVIEW Adisaputra, Arya Dibyo; Susilawati, Ni Made; Fatkhiya, Musa Fitri; Gibran, Nabial Chiekal; Futihat, Chilyati Eky
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1501

Abstract

Elderly patients are considered a vulnerable population, as advanced age may exacerbate existing conditions or predispose individuals to adverse effects such as hypoglycemia. While hypoglycemia most frequently occurs in patients with diabetes who are treated with insulin or oral hypoglycemic agents, it may also develop in non-diabetic individuals under certain circumstances. The use of beta-blockers has been identified as one potential contributing factor to hypoglycemic events. This article aims to review the adverse effects of beta-blocker therapy in relation to hypoglycemia among older adults. A narrative review was conducted through electronic databases including PubMed, Google Scholar, and ScienceDirect. The inclusion criteria were studies published within the last 10 years involving older patients who experienced hypoglycemia while receiving beta-blocker therapy. The search yielded 38 articles, of which only 4 met the inclusion criteria. In conclusion, the use of β-blockers appears to be associated with an increased risk of severe hypoglycemia; however, evidence specifically addressing the geriatric population remains limited.
Correlation of Blood Glucose, Creatinine, and Uric Acid with Blood Pressure in Hypertension Patients : Korelasi Glukosa Darah, Kreatinin, dan Asam Urat dengan Tekanan Darah Pada Pasien Hipertensi Faustine, Ingrid; Yuliet, Yuliet; Hardani, Ririen; Hamdani, Silviana; Alfia, Dhara; Susilawati, Ni Made; Adisaputra, Arya Dibyo
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 1 (2025): (March 2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i1.17638

Abstract

Poorly controlled hypertension in hypertensive patients can increase the risk of cardiovascular disease in the future. Some of the triggering factors are impaired kidney function which is characterized by an increase in creatinine levels and other factors as well, namely an increase in uric acid levels and an increase in blood sugar levels. This study aims to analyze the correlation between blood glucose, creatinine, and uric acid levels in hypertensive patients in Central Sulawesi. With a cross-sectional design, this observational study involved 50 adult hypertensive patients in health facilities. Data were taken from laboratory examination results during visits and analyzed descriptively and analytically. The results showed that 60% of hypertensive patients were female, 62% had a family history of hypertension, and 80% still had blood pressure that was included in the criteria for hypertension. As many as 34% of hypertensive patients had abnormal blood glucose levels, 32% had abnormal creatinine levels, and 26% had abnormal uric acid levels. Still, no relationship was found between the three with blood pressure (p> 0.05). The correlation between blood glucose and blood pressure was -0.221, creatinine and blood pressure was -0.112, and uric acid and blood pressure was 0.132. It can be concluded that there is a positive correlation with a very weak correlation strength between uric acid levels and blood pressure in hypertensive patients.
Personal Hygiene and Soil Transmitted Helminth Incidence in Elementary School Students Amanuban Barat District, South Central Timor Bia, Michael Bhadi; Susilawati, Ni Made; Rantesalu, Agnes; Octrisdey, Karol; Bire, Winioliski L.O. Rohi
JURNAL INFO KESEHATAN Vol 20 No 2 (2022): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol20.Iss2.932

Abstract

Soil-transmitted helminth infection remained a significant public health problem in many developing countries. Elementary school-age children dominated the cases in Indonesia due to poor personal hygiene. South Central Timor had the top three poverty and the highest stunting rates in East Nusa Tenggara. Research to examine the relationship between personal hygiene and the incidence of Soil-Transmitted Helminth infection had never been conducted in South Central Timor. The study population consisted of 279 elementary school students selected from Inpres Nulle Elementary School, Inpres Neonmat Elementary School, and GMIT Nulle Elementary School through the Multistage Random Sampling technique. It was obtained 160 children as the study samples. The study found that 46 children (29.0%) were positive for STH, and 114 (71.0%) were negative for STH. Furthermore, 30 (65.2%) were positive for hookworm, 14 (30.4%) were positive for Ascaris lumbricoides, and 2 (4.4%) children had mixed infections. Multiple Logistic Regression Tests showed a significant effect of washing hands with soap after defecating with p = 0.031 and OR = 7.158. Thus, if a child did not wash his hands with soap after defecating, he had a risk of STH infection by 7.158 times. Furthermore, the effect of eating habits obtained a p = 0.038 and an OR value = 0.133 with the possibility of eating habits that did not protect against STH infection. In addition, the effect of dirty nails obtained a p=0.064 and an OR=5.264, which indicated the risk of contracting STH by 5.264 times. The effect of snacking habit obtained a p = 0.005 and an OR=0.121. It can be concluded that the incidence of STH was simultaneously influenced by the habit of defecating on the ground, washing hands without soap after defecation, eating raw food, having dirty nails, and having poor snacking habits.
Uji Kualitatif Jagung Pulut (Zea mays certaina) sebagai Media Alternatif pertumbuhan Mycobacterium tuberculosis (TB) Yudhaswara, Novian Agni; Djami, Supriati W; Susilawati, Ni Made; Bria, Meliance
Jurnal Skala Husada : The Journal of Health Vol 20, No 2 (2023): JSH: Jurnal Skala Husada-The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v20i2.3091

Abstract

Tuberkulosis masih menjadi masalah kesehatan di Indonesia. Diagnosis laboratorium merupakan tahapan yang penting agar penderita segera mendapatkan pengobatan. Pewarnaan BTA masih menjadi pemeriksaan yang paling banyak dilakukan dikarenakan mudah cepat dan efektif. Gold standard untuk menegakkan diagnosis dengan pemeriksaan kultur. Kultur Mycobacterium tuberculosis relatif mahal dan membutuhkan waktu yang lama, maka diupayakan tersedia media kultur yang relatif lebih murah dan mudah didapat. Media jagung pulut merupakan media yang memungkinkan pertumbuhan sebagian besar organisme. Dengan penambahan telur pada Media jagung pulut mendukung pertumbuhan Mycobacterium tuberculosis. Penelitian ini bertujuan untuk mengetahui  pertumbuhan koloni Mycobacterium tuberculosis pada media jagung pulut yang ditambahkan telur dan gula dibandingkan dengan Lowenstein Jensen. Hasil penelitian menunjukkan pertumbuhan koloni Mycobacterium tuberculosis pada Media jagung pulut dan media Lowenstein Jensen dapat digunakan sebagai media pertumbuhan. Data dianalisis menggunakan uji Mann-Whitney, hasil uji menunjukan terdapat perbedaan jumlah koloni Mycobacterium tuberculosis pada jagung pulut  dan Lowenstein Jensen, dengan nilai probabilitas sig (2-tailed) yaitu 0,0001 0.05 dimana nilai rata-rata media stein Jensen lebih besar (2,73) di dibandingkan media uji (0,8-1,2)
The Relationship between Duration of Anti-Tuberculosis Treatment and Blood Urea Levels in Patients with Pulmonary Tuberculosis at Bakunase Community Helath Center Lidia Wulan Stevania Lapudo&#039;oh; Ni Made Susilawati; Byantarsih Widyaningrum; Michael Vallery Loueis Tumbol
Laboratory Journal of Infectious Diseases Vol. 2 No. 1 (2026): Laboratory Journal of Infectious Diseases
Publisher : Poltekkes Kemenkes Kupang

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Abstract

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a prevalent pathogen requiring prolonged treatment, typically lasting six months. The kidneys, as the primary excretory organs, must intensively filter pharmaceutical compounds throughout this period. This extended regimen can strain renal function and potentially lead to kidney damage, particularly with rifampicin and streptomycin, which have the highest risk of nephrotoxic effects compared to other anti-tuberculosis drugs. This study aimed to determine the relationship between treatment duration and blood urea levels among pulmonary TB patients at the Bakunase Community Health Center using a quantitative observational approach with a cross-sectional design. Researchers collected data with questionnaires and measured urea levels using the BT15i device. The statistical analysis of 30 samples using the Spearman rank correlation test yielded a correlation coefficient of 0,302 (30,2%) and a significance value of 0,105 (p > 0,05). These results indicate no significant correlation between the duration of anti-tuberculosis therapy and blood urea levels. Consequently, the findings suggest that prolonged TB treatment does not lead to a direct increase in urea levels among patients in this clinical setting, indicating that renal filtration remains relatively stable during the standard course of therapy.
Pigeonpea (Cajanus cajan L.) and Cowpea (Vigna unguiculata L.) Water as Alternative Growth Medium for Escherichia coli and Staphylococcus aureus in Laboratory with Minimum Infrastructure Norma Kambuno; Ninda P. Y. Amtaran; Sherly Dewu; Kuntum E. Nurdin; Ni Made Susilawati; Yoan Novicadlitha
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 3 No 2 (2021): Molecule analysis to advance laboratory diagnosis
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v3i2.2076

Abstract

The availability of non-synthetic media from natural ingredients is needed to answer the needs in laboratories where the price of nutrient media is quite expensive and there are limited supplies of material ware houses. Cowpea (Vigna unguiculata L.) and pigeonpea (Cajanus cajan L.) are the local foods of people of NTT (East Nusa Tenggara) which have a high enough nutritional content which has the potential to be developed into cheap, easy and simple non-synthetic media in making. The purpose of this study was to determine whether the agar media contained nutrient from cowpea and pigeonpea water can be used as a alternative for nutrient agar for the growth of Escherchia coli and Staphylococcus aureus bacteria. This research is a true experiment with posttest-only control design. The growth rate of S. aureus bacteria on pigeonpea medium, cowpea medium, nutrient agar medium, were 164 CFU/mL (SD=3,13), 161 CFU/mL (SD=3,02) and 164 CFU/mL (SD=3,21), respectively. The average growth of E. coli on cowpea medium, pigeonpea medium, and nutrient agar control medium were 163 CFU/mL (SD=2,79), 167 CFU/mL (SD-2,63) and 164 CFU/mL (SD=2,75) respectively. Test results ANOVA between pigeonpea medium, cowpea medium and nutrient medium in order to obtain p value = 0.145 (p> 0.05) for the growth of E. coli bacteria and p value = 0.393 (p> 0.05) for growth S. aureus. It was concluded that there was no difference between the number of bacterial colonies of E. coli and S. aureus on three medium. The pigeonpea medium and cowpea can be used to grow and alternative nutrient agar in order to grow bacteria E. coli and S. aureus.
Identifikasi Escherichia Coli Pada Es Batu Yang Dijual Di Warung Makan Kelurahan Liliba Kupang I Gede Putu Arnawa; Ni Made Susilawati; Marselina Sanbein
Jurnal Ventilator Vol. 1 No. 2 (2023): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v1i2.316

Abstract

Ice cubes are a food product that is often consumed by the community. Ice cubes are usually mixed in drinks to add freshness. Ice cubes are made from drinking water frozen at 0°C, although low temperatures can inhibit the growth of microorganism cells, ice cubes still have the possibility of containing contaminant microorganisms. Ice cubes that can cause diarrhea are ice cubes that contain pathogenic bacteria, one of which is Escherichia coli. Therefore it is necessary to check the quality of ice cubes microbiologically. This study aims to detect the presence of Escherichia coli in ice cubes sold by food stalls in the Liliba Village, Kupang. This type of research uses a descriptive method, where the population in this study is ice cubes which are sold in 10 different stalls in Liliba Kupang Village. The method used is Most Probable Number (MPN) with a variance of 5-1-1 followed by Gram staining and IMVIC test. From the results of the study, it can be found that ice cubes are sold in food stalls in Liliba Kupang Village, from 10 samples of ice cubes there is 1 sample that contains 10% Escherichia coli bacteria.
Pengaruh Lamanya Pengobatan Terhadap Profil Darah pada Penderita Tuberkulosis Paru di Puskesmas Oesapa Ni Made Susilawati; Novian Agni Yudhaswara; Karol Octrisdey
Jurnal Ventilator Vol. 1 No. 4 (2023): Desember : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v1i4.706

Abstract

Control efforts with the DOTS (Directly Observed Treatment Short-course) strategy have been implemented. The side effects of this drug will continue as long as the sufferer takes it, furthermore anti-TB drugs (OAT) will change the metabolism in the sufferer's body. Chronic effects that arise from OAT treatment include increased levels of uric acid, glucose and hemoglobin in the blood. From the results of a preliminary study, data collection was carried out on the number of pulmonary TB sufferers in Kupang City in 2021, amounting to 385. Of this number, 72 cases were found at the Oesapa Community Health Center who were smear positive for pulmonary TB and had recovered and were still undergoing treatment. For this reason, it is necessary to carry out research to determine blood glucose, uric acid and hemoglobin levels in pulmonary tuberculosis (TB) patients who take OAT (anti-TB drugs) before taking, after taking 2 months and 6 months of treatment. This research method is descriptive and statistical. Statistical analysis using One Way Anova and Linear Regression tests was used to determine the effect of length of treatment on blood profiles in pulmonary tuberculosis sufferers. TB sufferers with anti-tuberculosis drug therapy at the Oesapa Community Health Center based on the age of the patient, there were 11 sufferers aged <30 years (55%), 9 sufferers aged >30 years (45%). Based on gender, 13 sufferers were female (65%), 7 sufferers were male (35%). Hemoglobin levels checked before treatment showed a mean of 13.015 g/dL, during 2 months of treatment 13.185 g/dL, and after 6 months of treatment the mean was 11.94 g/dL. The current blood sugar levels from table 1.3 above which were checked before treatment showed an average of 137.7 g/dL, during 2 months of treatment 145.15 g/dL, and after 6 months of treatment the average was 144.15 g/dL. Uric acid levels were based on the respondent's length of treatment with an average uric acid level before treatment of 6.16 mg/dL, 2 months of treatment 5.92 mg/dL and 6 months of treatment 6.43 mg/dL. Hemoglobin levels, instant blood sugar and uric acid before, 2 months and 6 months of treatment showed a p value <0.05, meaning the data was not normally distributed. The results of the analysis using the Friedman anova test showed a p value (0.137) > 0.05. This means there is no difference in uric acid measurement values ??before, 2 months and 6 months of treatment. The results of the analysis using the Friedman anova test showed a p value (0.142) > 0.05. This means that there is no difference in blood sugar measurement values ??before, 2 months and 6 months of treatment. The results of the analysis using the Friedman anova test showed a p value (0.378) > 0.05. This means there is no difference in Hb measurement values ??before, 2 months and 6 months of treatment