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All Journal METAMORFOSA Journal of Biological Sciences E-Dimas: Jurnal Pengabdian kepada Masyarakat Public Health of Indonesia Jurnal Teknologi Laboratorium Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Community Development Journal Science Midwifery Jurnal Buana Farma Jurnal Pengabdian Masyarakat Sasambo JURNAL SKALA HUSADA: THE JOURNAL OF HEALTH Jurnal Pengabdian Masyarakat Nusantara Herbal Medicine Journal Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Kesehatan dan Kedokteran Jurnal Info Kesehatan
Ni Made Susilawati
Poltekkes Kemenkes Kupang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Analisis Bilirubin Dan Albumin Pada Penderita TB Tahap Awal Pengobatan Dan Tahap Akhir Menjalani Pengobatan Karol Octrisdey; Ni Made Susilawati; I Gede Putu Arnawa; Neiny Prisy Foekh
An-Najat Vol. 1 No. 4 (2023): NOVEMBER : An-Najat: Jurnal Ilmu Farmasi dan Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/an-najat.v1i4.513

Abstract

Pulmonary tuberculosis is a direct infectious disease caused by Mycobacterium tuberculosis. Most TB germs attack the lungs, but can also affect other body organs. Tuberculosis is spread by germs, so tuberculosis can be transmitted from one person to another when a sufferer coughs. To overcome this, WHO recommends a DOTS strategy, one of which is treatment. Tuberculosis treatment is given in packages in the form of Fixed Dose Combination Anti-Tuberculosis Drugs (OAT-KDT). It is feared that long-term TB treatment will cause side effects on the liver because OAT is hepatotoxic. This study aims to analyze albumin and bilirubin levels at the beginning of treatment and at the end of treatment. This research is called observational research because the researcher only observes the research subjects and looks for data related to the research without treating the research subjects. This type of research is a combination of documentation and observational studies with a cross-sectional study design (Cross Sectional Study), which can assess changes in liver function, in this case albumin and total bilirubin, from pulmonary TB sufferers at the beginning of treatment and at the end of treatment undergoing TB treatment. The sample in this study was 13 patients. The research results showed that the results of examinations for patients at the start of treatment: there were 10 respondents (76.9%) who had albumin levels that were included in the normal category, while the remaining 3 had low albumin levels. Examination results for patients at the start of treatment: there were 11 respondents (84.6%) who had bilirubin levels which were included in the normal category while the remaining 2 had high bilirubin levels. Examination results for patients at the end of treatment: there were 7 respondents (70%) whose albumin levels were included in the normal category while the remaining 3 had high albumin levels. Examination results for patients at the end of treatment: there were 8 respondents (80%) who had bilirubin levels which were included in the normal category while the remaining 2 had low bilirubin levels. The results of the difference test show that there is a difference in albumin at the beginning of treatment and at the end of treatment with a p value of 0.010 < 0.05. Meanwhile, the opposite result was obtained, namely that there was no difference in patient bilirubin levels at the beginning of treatment and at the end of treatment with p values of 0.312, 0.286 and 0.352 > 0.05, respectively.
PREVALENSI PENDERITA TUBERKULOSIS PARU DI PUSKESMAS OEKABITI KECAMATAN AMARASI KABUPATEN KUPANG PERIODE 2017-2020 Ni Made Susilawati; Karol Octrisdey; Fransiska
Jurnal Kesehatan dan Kedokteran Vol. 2 No. 1 (2023): Februari: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v2i1.538

Abstract

Tuberkulosis paru (TB) merupakan penyakit menular yang menjadi penyebab utama kematian di dunia. Pada tahun 2018 kasus TB Paru di Nusa Tenggara Timur mengalami peningkatan sebesar 6.833 kasus dan Kabupaten Kupang sebesar 3,212%. Tujuan penelitian ini adalah untuk mengetahui prevalensi kasus TB paru di Puskesmas Oekabiti Kecamatan Amarasi Kabupaten Kupang Tahun 2017-2020 berdasarkan umur, jenis kelamin, pemeriksaan dahak BTA, rontgen, jenis pasien dan alamat tempat tinggal. Metode penelitian yang digunakan adalah deskriptif dengan desain cross sectional. Hasil penelitian tahun 2017 terdapat prevalensi penderita TB paru sebanyak 2,85%, tahun 2018 sebanyak 2,62%, tahun 2019 sebanyak 1,6%, dan tahun 2020 sebanyak 0,91%. Hasil pemeriksaan apus dan rontgen positif sebanyak 70 orang (8%) dan negatif sebanyak 805 (92%). Hasil pemeriksaan sputum smear tertinggi adalah hasil sedikit (1,5%), dan hasil pemeriksaan terendah positif 1 dengan total 0,22%. Terdapat 4,7% jenis kelamin perempuan dan 3,31% jenis kelamin laki-laki, 3,65% usia tidak produktif, 1,6% usia tidak produktif dan 2,74% usia produktif. Pada pasien tipe baru ada 7,31%, pasien tipe relaps 0,6%, dan pasien tipe lain 0,1%. Berdasarkan wilayah tempat tinggal 8 desa dan 1 Kelurahan, penderita TB paru tertinggi berada di Desa Kotabes yaitu 1,6%. Prevalensi penderita TB paru dari tahun 2017-2020 mengalami penurunan setiap tahunnya. Penderita TB Paru paling banyak ditemukan pada wanita dengan hasil BTA negatif tertinggi, pada usia tidak produktif dengan jenis penderita baru terbanyak terdapat di Desa Kotabes.
Prevalensi Parasit Soil Transmitted Helminths Pada Anak Usia 2-9 Tahun Di Rukun Warga 04 Kelurahan Batakte Kecamatan Kupang Barat Kabupaten Kupang Tahun 2017 Ni Made Susilawati; Rini Kurniaty Smaut
JURNAL INFO KESEHATAN Vol 15 No 1 (2017): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Infection worm is one of the many diseases that occur in the community but less attention. This can be due to the worm group Soil-Transmitted Helminths (STH), a group of worms that cycle through the soil life, namely Ascaris lumbricoides, Trichuris trichiura, Strongyloides stercoralis, Necator americanus and Ancylostoma sp. Children more often found STH infected. The purpose of this study is to determine the prevalence of STH parasites in children aged 2-9 years in RW 04 Batakte Urban Village, Kupang Barat District, Kupang District in 2017. This type of research is a descriptive research that is the prevalence of Soil-Transmitted Helminths parasite. The subjects of this study were 59 children collected by total sampling method. The feces of the study subjects were collected, then examined by the native method to determine STH infection. The result of the research that has been done, the prevalence of Soil-Transmitted Helminths parasite in children aged 2-9 years in RW 04 Batakte urban village is 12% is 7 samples positive Ascaris lumbricoides (Ascariasis).
Evaluasi Kadar Glukosa Darah Pada Pasien Hipertensi yang Menggunakan Obat Golongan Angiostensin Receptor Bloker (ARB) di Rumah Sakit Umum Daerah Undata Palu Susilawati, Ni Made; Fresha, Winda; Rumi, Amelia; Adisaputra, Arya Dibyo
Herbal Medicine Journal Vol 8 No 1 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i1.151

Abstract

Hipertensi adalah kondisi medis yang ditandai dengan peningkatan tekanan darah arteri secara berkelanjutan. Salah satu golongan obat lini pertama pengobatan hipertensi adalah golongan Angiotensin Receptor Blocker (ARB). Obat ini berpotensi dapat dapat mempengaruhi metabolisme glukosa darah. Penelitian ini bertujuan untuk mengevaluasi kadar glukosa darah pada pasien hipertensi yang menjalani terapi menggunakan obat ARB, seperti losartan, candesartan, valsartan, dan telmisartan, di RSUD Undata Palu. Penelitian ini dilakukan dengan metode cross-sectional secara prospektif, melibatkan 30 pasien yang memenuhi kriteria inklusi. Pasien yang diteliti berusia ≥18 tahun, telah menjalani terapi ARB selama 3 bulan, memiliki hipertensi tanpa diabetes melitus, dan tidak menggunakan obat lain yang memengaruhi kadar glukosa darah. Pengukuran dilakukan menggunakan glucometer Accu-Chek Performa. Hasilnya menunjukkan penurunan kadar glukosa darah puasa dari rata-rata 113.83 mg/dl menjadi 107.83 mg/dl, dengan selisih 6.367 mg/dl. Uji statistik menunjukkan p=0.049 (p<0.05), yang mengindikasikan bahwa ARB dapat menurunkan kadar glukosa darah pada pasien hipertensi.
EFEK PENGGUNAAN BETA BLOCKER TERHADAP KEJADIAN HIPOGLIKEMIA PADA LANSIA: NARRATIVE REVIEW Adisaputra, Arya Dibyo; Susilawati, Ni Made; Fatkhiya, Musa Fitri; Gibran, Nabial Chiekal; Futihat, Chilyati Eky
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1501

Abstract

Elderly patients are considered a vulnerable population, as advanced age may exacerbate existing conditions or predispose individuals to adverse effects such as hypoglycemia. While hypoglycemia most frequently occurs in patients with diabetes who are treated with insulin or oral hypoglycemic agents, it may also develop in non-diabetic individuals under certain circumstances. The use of beta-blockers has been identified as one potential contributing factor to hypoglycemic events. This article aims to review the adverse effects of beta-blocker therapy in relation to hypoglycemia among older adults. A narrative review was conducted through electronic databases including PubMed, Google Scholar, and ScienceDirect. The inclusion criteria were studies published within the last 10 years involving older patients who experienced hypoglycemia while receiving beta-blocker therapy. The search yielded 38 articles, of which only 4 met the inclusion criteria. In conclusion, the use of β-blockers appears to be associated with an increased risk of severe hypoglycemia; however, evidence specifically addressing the geriatric population remains limited.
Correlation of Blood Glucose, Creatinine, and Uric Acid with Blood Pressure in Hypertension Patients : Korelasi Glukosa Darah, Kreatinin, dan Asam Urat dengan Tekanan Darah Pada Pasien Hipertensi Faustine, Ingrid; Yuliet, Yuliet; Hardani, Ririen; Hamdani, Silviana; Alfia, Dhara; Susilawati, Ni Made; Adisaputra, Arya Dibyo
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 1 (2025): (March 2025)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i1.17638

Abstract

Poorly controlled hypertension in hypertensive patients can increase the risk of cardiovascular disease in the future. Some of the triggering factors are impaired kidney function which is characterized by an increase in creatinine levels and other factors as well, namely an increase in uric acid levels and an increase in blood sugar levels. This study aims to analyze the correlation between blood glucose, creatinine, and uric acid levels in hypertensive patients in Central Sulawesi. With a cross-sectional design, this observational study involved 50 adult hypertensive patients in health facilities. Data were taken from laboratory examination results during visits and analyzed descriptively and analytically. The results showed that 60% of hypertensive patients were female, 62% had a family history of hypertension, and 80% still had blood pressure that was included in the criteria for hypertension. As many as 34% of hypertensive patients had abnormal blood glucose levels, 32% had abnormal creatinine levels, and 26% had abnormal uric acid levels. Still, no relationship was found between the three with blood pressure (p> 0.05). The correlation between blood glucose and blood pressure was -0.221, creatinine and blood pressure was -0.112, and uric acid and blood pressure was 0.132. It can be concluded that there is a positive correlation with a very weak correlation strength between uric acid levels and blood pressure in hypertensive patients.
Personal Hygiene and Soil Transmitted Helminth Incidence in Elementary School Students Amanuban Barat District, South Central Timor Bia, Michael Bhadi; Susilawati, Ni Made; Rantesalu, Agnes; Octrisdey, Karol; Bire, Winioliski L.O. Rohi
JURNAL INFO KESEHATAN Vol 20 No 2 (2022): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol20.Iss2.932

Abstract

Soil-transmitted helminth infection remained a significant public health problem in many developing countries. Elementary school-age children dominated the cases in Indonesia due to poor personal hygiene. South Central Timor had the top three poverty and the highest stunting rates in East Nusa Tenggara. Research to examine the relationship between personal hygiene and the incidence of Soil-Transmitted Helminth infection had never been conducted in South Central Timor. The study population consisted of 279 elementary school students selected from Inpres Nulle Elementary School, Inpres Neonmat Elementary School, and GMIT Nulle Elementary School through the Multistage Random Sampling technique. It was obtained 160 children as the study samples. The study found that 46 children (29.0%) were positive for STH, and 114 (71.0%) were negative for STH. Furthermore, 30 (65.2%) were positive for hookworm, 14 (30.4%) were positive for Ascaris lumbricoides, and 2 (4.4%) children had mixed infections. Multiple Logistic Regression Tests showed a significant effect of washing hands with soap after defecating with p = 0.031 and OR = 7.158. Thus, if a child did not wash his hands with soap after defecating, he had a risk of STH infection by 7.158 times. Furthermore, the effect of eating habits obtained a p = 0.038 and an OR value = 0.133 with the possibility of eating habits that did not protect against STH infection. In addition, the effect of dirty nails obtained a p=0.064 and an OR=5.264, which indicated the risk of contracting STH by 5.264 times. The effect of snacking habit obtained a p = 0.005 and an OR=0.121. It can be concluded that the incidence of STH was simultaneously influenced by the habit of defecating on the ground, washing hands without soap after defecation, eating raw food, having dirty nails, and having poor snacking habits.
Uji Kualitatif Jagung Pulut (Zea mays certaina) sebagai Media Alternatif pertumbuhan Mycobacterium tuberculosis (TB) Yudhaswara, Novian Agni; Djami, Supriati W; Susilawati, Ni Made; Bria, Meliance
Jurnal Skala Husada : The Journal of Health Vol 20, No 2 (2023): JSH: Jurnal Skala Husada-The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v20i2.3091

Abstract

Tuberkulosis masih menjadi masalah kesehatan di Indonesia. Diagnosis laboratorium merupakan tahapan yang penting agar penderita segera mendapatkan pengobatan. Pewarnaan BTA masih menjadi pemeriksaan yang paling banyak dilakukan dikarenakan mudah cepat dan efektif. Gold standard untuk menegakkan diagnosis dengan pemeriksaan kultur. Kultur Mycobacterium tuberculosis relatif mahal dan membutuhkan waktu yang lama, maka diupayakan tersedia media kultur yang relatif lebih murah dan mudah didapat. Media jagung pulut merupakan media yang memungkinkan pertumbuhan sebagian besar organisme. Dengan penambahan telur pada Media jagung pulut mendukung pertumbuhan Mycobacterium tuberculosis. Penelitian ini bertujuan untuk mengetahui  pertumbuhan koloni Mycobacterium tuberculosis pada media jagung pulut yang ditambahkan telur dan gula dibandingkan dengan Lowenstein Jensen. Hasil penelitian menunjukkan pertumbuhan koloni Mycobacterium tuberculosis pada Media jagung pulut dan media Lowenstein Jensen dapat digunakan sebagai media pertumbuhan. Data dianalisis menggunakan uji Mann-Whitney, hasil uji menunjukan terdapat perbedaan jumlah koloni Mycobacterium tuberculosis pada jagung pulut  dan Lowenstein Jensen, dengan nilai probabilitas sig (2-tailed) yaitu 0,0001 0.05 dimana nilai rata-rata media stein Jensen lebih besar (2,73) di dibandingkan media uji (0,8-1,2)
Co-Authors Adisaputra, Arya Dibyo Agnes Rantesalu Agustina W Djuma Agustina W. Djuma Agustina Welhelmina Djuma Alfia, Dhara amelia rumi, amelia Arnawa, I Gede Putu Bia, Michael Bhadi Bia, Mikhael B. Bire, Winioliski L.O. Rohi Djami, Supriati W Fatkhiya, Musa Fitri Ferry WF Waangsir Fransiska Fresha, Winda Futihat, Chilyati Eky Gibran, Nabial Chiekal Hamdani, Silviana I Gede Putu Arnawa I Made Oka Adi Parwata Ingrid Faustine Karol Octrisdey Kuntum E. Nurdin Marni Tangkelangi Melany F. Bessie Meliance Bria Meliance Bria Mikhael B. Bia Neiny P Foekh Neiny Prisy Foekh Ninda P. Y. Amtaran Norma Kambuno Norma Tiku Kambuno Novian Agni Novicadlitha, Yoan Nurdin, Kuntum Ekawati Rini Kurniaty Smaut Ririen Hardani Rohi Bire, Winioliski L. O. Sherly Dewu Smaut, Rini Kurniaty Supriati Wila Djami Winioliski L.O Rohi Bire Wuan, Adrianus Ola Yan Ramona Yoan Novicadlitha Yoan Novicadlitha Yuliet Yuliet Yustina K. Wawo Aja