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All Journal Medical Journal of Indonesia Berkala Ilmu Kesehatan Kulit dan Kelamin ASEAN Journal of Community Engagement JOURNAL LA MEDIHEALTICO eJournal Kedokteran Indonesia Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Jurnal Inovasi dan Teknologi Pendidikan Cermin Dunia Kedokteran
Sandra Widaty
Faculty Of Medicine University Of Indonesia/ Cipto Mangunkusumo Hospital, Jakarta
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Onikomikosis yang Disebabkan oleh Kodamaea ohmeri pada Seorang Pasien dengan Virus Imunodefisiensi Manusia (HIV) – Laporan Kasus: Laporan Kasus Nadliroh, Siti; Wahid, Mardiastuti; Sjatha, Fithriyah; Haliman, Cliff Clarence; Widaty, Sandra; Mutiara, Rizka; Pratama, Aditya Indra; Asri, Rizkia Chairani; Adawiyah, Robiatul; Kusumaningrum, Ardiana
Cermin Dunia Kedokteran Vol 53 No 07 (2026): Juli 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i07.1895

Abstract

Introduction: Onychomycosis is a fungal nail infection usually caused by dermatophytes. Kodamaea ohmeri is a rare fungus that has been reported as a pathogen capable of causing onychomycosis and systemic infections. This yeast-like fungus is often misidentified as Candida sp. A complete identification is required for accurate results. Case: A 40-year-old male with HIV presented with yellow and brittle fingernails for 2 months. KOH examination of nail scrapings was performed, followed by fungal culture. The isolate was identified in parallel using the Integral System Yeast Plus, Vitek-2, MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry), and sequencing, and the result was Kodamaea ohmeri. The patient received oral itraconazole and topical ketoconazole. Discussion: Onychomycosis in HIV patients is caused by low immunity, high viral load, and low CD4 values. In this case, K. ohmeri was successfully identified using Vitek-2, MALDI-TOF, and ITS (Internal Transcribed Spacer) area sequencing, while the Integral System Yeast Plus misidentified the isolate as Candida tropicalis. There was clinical improvement in the nail after treatment. Conclusion: Onychomycosis in HIV patients can be caused by Kodamaea ohmeri. Identification can be done with Vitek-2 and MALDI-TOF.
Co-Authors Andira Hardjodipuro Hardjodipuro Anna Rozaliyani Ardiana Kusumaningrum Aria Kekalih Ariyati Yosi Artini Wijayanti Islami Asri, Rizkia Chairani Bianti, Marsha Cornain, Emilina Faradila Darmawan, Irene Dewi Friska Dewi Lestarini Diantha, Soemantri Dini Daniaty Eliza Miranda Eliza Miranda Eliza Miranda Githa Rahmayunita Haliman, Cliff Clarence Hamzah Hamzah Hanny Nilasari Hansen Angkasa Hartanto, David Dwiadiputra Henry Wan-Peng Lim Herwinda Brahmanti Indah, Chinda Liaska Irma Bernadette Islami, Artini Wijayanti Joanne Natasha Joses Saputra Kartika, Emiliana Keiko Gunardi Krisanti, Roro Inge Ade Kusmarinah Bramono Lili Legiawati Lili Legiawati Lili Legiawati Lim, Henry W Lis Surachmiati Luddwi Achmad Rizky M. Yulianto Listiawan Marissa, Melani Marsha Bianti Martinus Martinus Melinda, Thong Felicia Menaldi, Sri Linuwih Susetyo Wardhani Mochamad H Azis Mufqi Handaru Priyanto Mustika, Rita Mutiara, Rizka Nadliroh, Siti Novita Suprapto Nugraheni Pasaribu, Uly Aanda Maria Oktarina, Caroline Oktavia, Nikken Rima Pandelaki, Paulus Anung Anindita Pratama, Aditya Indra Purnawan, Shafira Anindya Rahadi Rihatmadja Rhida Sarly Amalia Rilanda, Risa Rinadewi Astriningrum Rizky, Luddwi Achmad Robiatul Adawiyah Saleha Sungkar Sammy Yahya Sari, Siti Maulidya Shannaz Nadia Yusharyahya Sirait, Sondang Panjaitan Situmeang, Irhen SJATHA, FITHRIYAH Sondang Pandjaitan Sirait Sri L. Menaldi Sri Linuwih Menaldi Sri Linuwih Susetyo Wardhani, Sri Linuwih Susetyo Sri Wahdini Sujudi, Yufanti Surachmiati Suseno, Lis Suryanti Teffy Nuary Triana Agustin Tugiran, Mulyati Wahid, Mardiastuti Wati, Huda Marlina Windy Keumala Budianti Yahya, Sammy Yenny Rachmawati Yosi, Ariyati Yudo Irawan Yudo Irawan