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FACTORS AFFECTING STUDENT'S QUALITY IN HIGHER EDUCATION William, William; Lubis, Tya Wildana Hapsari
Jurnal Aplikasi Manajemen Vol. 19 No. 1 (2021)
Publisher : Universitas Brawijaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jam.2021.019.01.04

Abstract

This study aims to research the influence of student's behavior, lecturer's competency, and school's facilities on the student's quality at Sekolah Tinggi Manajemen Informatika dan Komputer (STMIK) Mikroskil and Sekolah Tinggi Ilmu Ekonomi (STIE) Mikroskil Mikroskil. This research is a descriptive study with a quantitative method approach. The population in this study were undergraduate students totaling 3.493 students, the sample size used in this study is 360 students obtained using the Slovin formula. The sampling technique is stratified random sampling techniques applied to each study program. The data analysis method is multiple linear regression analysis. The results showed that student's behavior, lecturer's competency, and school's facilities had a positive and significant effect on Student's quality by 43.5 %. Future researchers are suggested to carry out the process and learning management in improving student's quality.
Identifikasi peran hsa-miR-4454 pada penuaan kulit: Studi klinis dan bioinformatik Ekowati, Ana Lucia; William, William; Soeselo, Daniel Ardian; Siswanto, Ferbian Milas
Bahasa Indonesia Vol 24 No 1 (2025): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v24i1.5627

Abstract

Pendahuluan: Penuaan kulit adalah proses kompleks yang melibatkan faktor intrinsik dan ekstrinsik. Berbagai parameter untuk mengevaluasi karakteristik kulit telah diusulkan. Namun, biomarker yang akurat untuk penuaan kulit dan hubungan mekanisme molekuler penuaan kulit masih sangat terbatas. Penelitian ini bertujuan untuk memvalidasi peran mikroRNA (miRNA) dalam regulasi epigenetik penuaan kulit sebagai kandidat biomarker dan target terapi. Metode: Profil ekspresi miRNA kakek dan cucu dari 2 famili Jawa dibandingkan untuk memilih kandidat miRNA yang memiliki perbedaan ekspresi pada jaringan kulit. Selanjutnya, miRNA yang mengalami perubahan ekspresi tersebut dianalisis fungsi dan perannya pada tingkat molekuler dengan pendekatan bioinformatika. Hasil: Hasil profiling menunjukkan miR-4454 yang konsisten mengalami peningkatan ekspresi pada kedua famili yaitu sebesar 3,318 pada famili I dan 9,315 pada famili II. Berdasarkan data dari GeneCards, miR-4454 memiliki ekspresi yang cukup tinggi pada kulit dan diekspresikan pada seluruh komponen sel. Analisis data dari GWAS mengindikasikan bahwa miR-4454 terlibat dalam pengaturan panjang telomer. Analisis gen target dengan menggunakan TargetScanHuman, miRTarBase, miRTargetLink dilanjutkan dengan pengayaan ontologi gen dan jalur molekuler dengan platform EnrichR menunjukkan miR-4454 berperan dalam regulasi produksi IL-12, respons terhadap radiasi, autofagi, metabolisme, FoxO signaling pathway, dan cellular senescence. Gen ataxia telangiectasia mutated (ATM) dan mitogen-activated protein kinase 14 (MAPK14) diduga berperan penting pada regulasi penuaan kulit akibat miR-4454 karena keterlibatannya pada cellular senescence. Simpulan: Pada penuaan kulit, ekspresi miR-4454 yang tinggi berpotensi digunakan sebagai kandidat biomarker dan dasar pengembangan target terapi. Gen ATM dan MAPK14 merupakan dua kandidat target miR-4454.   
Faktor - Faktor Yang Mempengaruhi Nilai Perusahaan Pada Perusahaan Farmasi Priadi, Dina Puspita; William, William; Putri, Arie Pratania; Purba, Rahima Br
Community Engagement and Emergence Journal (CEEJ) Vol. 6 No. 1 (2025): Community Engagement & Emergence Journal (CEEJ)
Publisher : Yayasan Riset dan Pengembangan Intelektual

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37385/ceej.v6i1.8240

Abstract

Perusahaan farmasi adalah entitas bisnis yang bergerak dalam bidang penelitian, pengembangan, produksi, dan pemasaran obat-obatan, vaksin, serta produk kesehatan lainnya. Perusahaan ini berfokus pada kegiatan komersial yang melibatkan penemuan dan distribusi obat-obatan, khususnyadalam bidang kesehatan. Penelitian ini bertujuan untuk mengetahui pengaruh green accounting, solvabilitas, perputaran piutang, dan perputaran persediaan terhadap nilai perusahaan pada sub sektor pertambangan yang terdaftar di Bursa Efek Indonesia. Pengambilan sampel dilakukan dengan teknik purposive sampling, yang menghasilkan sebanyak 68 sampel. Hasil penelitian secara parsial menunjukkan bahwa Return on Asset (ROA) berpengaruh negatif namun tidak signifikan terhadap Price to Book Value (PBV). Current Ratio juga tidak berpengaruh dan tidak signifikan terhadap PBV. Begitu pula dengan Return on Equity (ROE) dan Debt to Equity Ratio (DER) yang tidak menunjukkan pengaruh signifikan terhadap PBV. Secara simultan, variabel ROA, CR, ROE, dan DER juga tidak berpengaruh signifikan terhadap Price to Book Value.
Studi Meta-Analisis Transcranial Doppler Terhadap Glasgow Outcome Score Pada Cedera Otak Traumatik William, William; Tumewah, Rizal; Ngantung, Denny; Pertiwi, Junita Maja; Tumboimbela, Melke; Wariki, Windy Mariane Virenia
MAHESA : Malahayati Health Student Journal Vol 5, No 7 (2025): Volume 5 Nomor 7 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i7.18851

Abstract

ABSTRACT Traumatic brain injury (TBI) through primary and secondary brain injury causes ischemic, hypoxic, cerebral edema, increased intracranial pressure, which are related to physiological, emotional damage and disability. Transcranial Doppler (TCD) as a diagnostic tool can monitor increased intracranial pressure through hypoperfusion and also monitor vasospasm. This meta-analysis study aims to determine TCD as a diagnostic tool in predicting outcomes in TBI cases. Observational studies were taken on TCD examination in TBI cases. Clinical outcomes were assessed based on the Glasgow Outcome Score (GOS), Glasgow Outcome Score-Extended (GOS-E), and mortality. Secondary outcomes were the cut-off values of the Pulsatility Index (PI) and Lindegaard Ratio (LR) related to GOS, GOSE and mortality. Abnormal TCD values in TBI cases would have a >11 times greater likelihood of poor GOS (OR 11.51, 95% CI 7.75 to 17.10). Abnormal TCD had a >11 times greater likelihood of causing death compared to normal TCD (OR 11.05, 95% CI 5.99 to 20.40). Hypoperfusion on TCD had a >6 times greater likelihood of being associated with poor GOS (OR 6.33, 95% CI 0.28 to 144.48) and had a >22 times greater likelihood of causing death compared to vasospasm on TCD (OR 22.86, 95% CI 0.70 to 751.27). ROC curve analysis showed that the PI cut-off value of 1.03 and LR 3.3 were associated with poor GOS. TCD can be used as a diagnostic tool to predict poor GOS outcomes and mortality in TBI cases. Keywords: Transcranial Doppler, Glasgow Outcome Score, Traumatic Brain Injury ABSTRAK Cedera otak traumatik (COT) melalui cedera otak primer dan sekunder menyebabkan proses iskemik, hipoksik, edema serebral, kenaikan tekanan intrakranial, yang berkaitan dengan kerusakan fisiologis, emosional dan disabilitas. Transcranial Doppler (TCD) sebagai alat penunjang diagnostik dapat memantau kenaikan tekanan intrakranial melalui hipoperfusi dan juga memantau vasospasme. Studi meta-analisis ini bertujuan untuk menentukan TCD sebagai alat penunjang diagnostik dalam memprediksi luaran pada kasus COT. Studi observasional pemantauan TCD pada kasus COT diambil untuk dilakukan meta-analisis. Luaran klinis dinilai berdasarkan Glasgow Outcome Score (GOS), Glasgow Outcome Score-Extended (GOS-E), dan mortalitas. Luaran sekunder berupa nilai cut-off Pulsatility Index (PI) dan Lindegaard Ratio (LR) yang berhubungan dengan GOS, GOSE dan mortalitas. Nilai abnormal pada TCD akan memiliki kemungkinan >11 kali luaran GOS buruk (OR 11.51, 95% CI 7.75 to 17.10). TCD abnormal memiliki kemungkinan >11 kali menyebabkan kematian dibandingkan TCD normal (OR 11.05, 95% CI 5.99 to 20.40). Hipoperfusi pada TCD memiliki kemungkinan >6 kali berkaitan dengan GOS buruk (OR 6.33, 95% CI 0.28 to 144.48) dan memiliki kemungkinan >22 kali menyebabkan kematian dibandingkan vasospasme pada TCD (OR 22.86, 95% CI 0.70 to 751.27). Analisis kurva ROC memperlihatkan nilai cut-off PI 1.03 dan LR 3.3 berkaitan dengan GOS yang buruk. TCD dapat digunakan sebagai alat diagnostik untuk memprediksi luaran GOS buruk dan mortalitas pada kasus COT. Kata Kunci: Transcranial Doppler, Glasgow Outcome Score, Cedera Otak Traumatik 
Designing Startup Application “LaKu” for MSME in Riau Based on Android Marlim, Yulvia Nora; William, William; Susanti, Wilda; Fadrul, Fadrul; Nicholas Renaldo; Musa, Sulaiman; Wahid, Nabila
Journal of Applied Business and Technology Vol. 6 No. 2 (2025): Journal of Applied Business and Technology
Publisher : Institut Bisnis dan Teknologi Pelita Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35145/jabt.v6i2.228

Abstract

Department of Industry, Trade, Cooperatives and SMEs (DITCS) of Riau has an important role in supporting 631,347 groups of Micro, Small and Medium Enterprises (MSMEs) engaged in various fields such as handicrafts, batik, songket, and food and beverages. Many MSME merchants still market their products traditionally through the neighborhood and word of mouth, while online marketing faces a big challenge because they have to compete with well-known brands, making them difficult to develop and grow their business. To overcome these problems, an Android-based application “LaKu” was developed that aims to help MSME merchants in expanding their marketing reach and increasing their competitiveness in Riau. The development of this application uses the Extreme Programming (XP) method which consists of four main steps: Planning, Design, Code, and Testing. The development results show that the “LaKu” application can be an effective digital marketing platform, helping MSMEs in promoting products more widely without having to compete directly with big brands. With this application, MSMEs are able to increase competitiveness and contribute to local economic growth in Riau Province.
Perbandingan Kinerja Naïve Bayes dan Random Forest dalam Mendeteksi Berita Palsu William, William; Handhayani, Teny
JISKA (Jurnal Informatika Sunan Kalijaga) Vol. 10 No. 2 (2025): May 2025
Publisher : UIN Sunan Kalijaga Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/jiska.2025.10.2.137-144

Abstract

Fake news has become a serious problem in today's digital era. The existence of fake news can have various negative impacts, including the spread of misinformation, social unrest, and economic losses. This study compares the performance of Naïve Bayes and Random Forest classification methods in detecting fake news. Both methods were evaluated on a news dataset comprising 44,898 samples. It uses public data from the Kaggle repository. The news samples are represented by four features: title, news content, subject, and news date. This data is then subjected to cleaning, stemming, tokenization, and feature extraction. The results indicate that the Random Forest method outperforms the Naïve Bayes method. The Random Forest method has an accuracy of 99%, while the Naïve Bayes method has an accuracy of 96%. In general, this research demonstrates that the Random Forest method can be a viable alternative for detecting fake news.
Exploring the Interplay of Mental and Metabolic Factors in Erectile Dysfunction Management: A Case Report Angellee, Jesselyn; Suharyani, Sally; Tanojo, Tjahjo Djojo; Pakpahan, Cennikon; William, William; Utomo, Natasha Susanto
Indonesian Andrology and Biomedical Journal Vol. 6 No. 1 (2025): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v6i1.66725

Abstract

Background: Erectile dysfunction (ED) affects 20-50% of men globally and considerably diminishes the patients’ and their partners’ quality of life. This condition has multifactorial causes, including depression and metabolic syndrome, resulting in a complicated interaction of physical and psychological components. Case: A man in his mid-twenties presented to the Andrology outpatient clinic at Dr. Soetomo General Hospital with a sudden onset of ED, reporting a decrease in his Erection Hardness Score (EHS) from 3-4 to 1 following penetration attempts. He had a history of childhood attention deficit hyperactivity disorder (ADHD) and recent unemployment, resulting in profound depression. Prior inconsistent treatments encompassed sertraline, fluvoxamine, and clobazam. Physical and laboratory examinations revealed metabolic syndrome. The patient was diagnosed with severe ED secondary to mixed etiology, class II obesity, major depressive episode, and metabolic syndrome. He received education on the diagnosis, possible underlying causes, and management options. Discussion: The case presented illustrates the intricate interplay between ED and comorbidities such as depression and metabolic syndrome. Depression exacerbates ED through hormonal dysregulation and reduced parasympathetic activity, while metabolic syndrome contributes to ED through endothelial dysfunction and nitric oxide (NO) depletion. Effective ED management requires a multidisciplinary approach, combining lifestyle modifications, psychological support, and pharmacological treatment. Tailored strategies addressing both physical and psychological aspects are essential for improving outcomes. Conclusion: Comprehensive and integrative care in managing ED, particularly when associated with complex comorbidities, is needed to enhance the patient’s erectile function and quality of life.
Peningkatan pemanfaatan sistem automasi perkantoran pada perkumpulan pemuda Theravada Indonesia Paulus, Paulus; Hanes, Hanes; Lestari, Wulan Sri; William, William
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 4 (2025): Juli
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i4.31982

Abstract

AbstrakPemuda Theravada Indonesia adalah perkumpulan sosial keagamaan berskala nasional dengan kepengurusan  yang tersebar di 23 provinsi di seluruh Indonesia. Organisasi ini telah memanfaatkan sistem automasi perkantoran berupa Microsoft 365 dan Google Workspace untuk organisasi nirlaba. Akan tetapi, tingkat pemanfaatan kedua sistem tersebut masih sangat rendah. Kegiatan Pengabdian pada Masyarakat ini bertujuan untuk mengeksplorasi dan mengimplementasikan solusi agar sistem automasi perkantoran dapat dimanfaatkan lebih efektif untuk mendukung kegiatan Perkumpulan. Tahapan yang dilakukan tim pelaksana mencakup analisis kondisi, merumuskan solusi, implementasi sistem, dan memberikan dukungan / pendampingan. Hasil wawancara, diskusi, observasi sistem, dan studi dokumen Perkumpulan memperlihatkan bahwa rendahnya pemanfaatan sistem automasi perkantoran disebabkan beberapa kendala. Kendala yang dimaksud yaitu belum ada pengurus Perkumpulan yang bertugas sebagai pengelola sistem / teknologi, kurangnya pelatihan sistem dan sosialisasi, dan belum ada program kerja sehubungan peningkatan sistem automasi perkantoran. Tim Pengabdian kepada Masyarakat membantu merumuskan solusi agar Perkumpulan membuat kebijakan internal tentang pemanfaatan sistem automasi perkantoran. Berdasarkan kebijakan tersebut, tim pelaksana melakukan implementasi dan kemudian memberikan dukungan / pendampingan selama implementasi. Pendampingan dilakukan dalam bentuk sosialisasi dan pelatihan yang diikuti oleh 90 anggota Perkumpulan dan dilakukan secara daring. Upaya ini membuahkan dampak positif terhadap efisiensi kegiatan, kolaborasi dan pengelolaan data Perkumpulan. Kata kunci: organisasi nirlaba; digitalisasi; automasi perkantoran; efisiensi proses; Microsoft 365. AbstractPemuda Theravada Indonesia, a national socio-religious association with branches in 23 provinces across Indonesia. This organization has utilized office automation systems such as Microsoft 365 and Google Workspace for nonprofit organizations. However, the level of utilization of both systems is still very low. This Community Service aims to explore and implement solutions to enhance the effective use of office automation systems in the Association’s activities. The Community Service Team conducted condition analysis, formulated solutions, implemented the systems, and provided support / assistance. Interviews, discussions, system observations, and document studies revealed that the low utilization of office automation systems is due to several obstacles. These obstacles include the absence of system / technology managers, lack of system training and socialization, and the absence of work programs related to the enhancement of office automation systems. The Community Service Team assisted in formulating solutions for the Association to establish internal policies on the utilization of office automation systems. Based on these policies, the implementation team carried out the implementation and subsequently provided support and assistance for the Association during the implementation. Mentoring was carried out in the form of socialization and training attended by 90 members of the Association and was carried out online. This effort has had a positive impact on the efficiency of activities, collaboration and data management of the Association. Keywords: nonprofit organization; digitalization; office automation; process efficiency; Microsoft 365.
Pelatihan Desain Grafis sebagai Pendamping Ekskul Desain Grafis di SMAK Yos Sudarso Deli; William, William; Diny
National Conference for Community Service Project (NaCosPro) Vol. 7 No. 01 (2025): The 7th National Conference for Community Service Project 2025
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Universitas Internasional Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37253/nacospro.v7i01.10806

Abstract

Abstrak Kegiatan ekstrakurikuler di sekolah merupakan salah satu wadah penting untuk mengembangkan minat dan bakat siswa di luar pembelajaran akademik. Di SMAK Yos Sudarso Batam, salah satu kegiatan ekstrakurikuler yang ditawarkan adalah desain grafis. Namun, kegiatan ini masih menghadapi tantangan seperti kurangnya materi pembelajaran yang terstruktur dan minimnya pendampingan dari tenaga dengan latar belakang profesional. Melalui kegiatan kerja praktik ini, dilakukan pendampingan dalam bentuk perancangan dan pelaksanaan materi ajar berupa modul pembelajaran desain grafis dengan pendekatan yang sederhana dan aplikatif. Materi yang disampaikan meliputi teori warna, pengenalan software Figma, serta praktik membuat kartu nama. Kegiatan ini disusun menggunakan metode MDLC (Multimedia Development Life Cycle) agar proses perancangan modul dapat berjalan sistematis. Hasil kegiatan menunjukkan bahwa siswa lebih memahami dasar desain secara visual dan mampu menghasilkan karya desain sederhana secara mandiri. Kata Kunci: Ekstrakurikuler, Desain Grafis, SMAK Yos Sudarso, Figma, Teori Warna, Namecard. Abstract Extracurricular activities at school are an essential platform for developing students' interests and talents beyond academic learning. At SMAK Yos Sudarso Batam, one of the offered programs is graphic design. However, this activity still faces challenges such as the lack of structured learning materials and limited guidance from professionals. Through this internship project, assistance was provided in the form of designing and delivering structured learning content through a graphic design module with a simple and practical approach. The materials covered include color theory, an introduction to the Figma design software, and a hands-on project of creating a name card. The entire process followed the MDLC (Multimedia Development Life Cycle) method to ensure a systematic development of the learning module. As a result, students demonstrated better understanding of visual design fundamentals and were able to create simple design works independently. Keywords: Extracurricular, Graphic Design, SMAK Yos Sudarso, Figma, Color Theory, Namecard.
PRODUK KREATIF DAN KEWIRAUSAHAAN DALAM PEMBUATAN KUE PAO Damanik, Dennys Paulus Parlindungan; Simanjuntak, Demak Claudia Yosephine; Sari, Ike Rukmana; Purnasari, Nina; William, William
Jurnal Pengabdian Bukit Pengharapan Vol. 5 No. 1 (2025)
Publisher : LPPM Institut Teknologi dan Bisnis Kristen Bukit Pengarapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61696/jurdian.v5i1.911

Abstract

Creativity is the process of turning new and innovative ideas into tangible results, practices and solutions. This is an important component of entrepreneurship, because individuals must be creative to identify and exploit opportunities. Where existing opportunities can be a solution for the community to meet their daily needs, especially for teenagers who have an interest and intention in building their business. Where high school level teenagers usually lack motivation to develop themselves. This community service activity is aimed at teenagers at high school level with the aim of motivating them to develop their creativity so that it is hoped that young entrepreneurs will emerge who will strengthen MSMEs in Indonesia. The methods used in this community service include presentations and questions and answers so that participants can better understand the topic and be motivated to develop their creativity. The results of this activity were quite satisfactory, with several participants starting to open small businesses such as selling snacks made by themselves in the school environment and in their home environment
Co-Authors , Rahima Br Purba A.A. Ketut Agung Cahyawan W Agatha, Nabila Agustinus Agustinus Alfian, Achmad Alvina, June Ana Lucia Ekowati Anderes Gui, Anderes Angellee, Jesselyn Arie Pratania Putri Arruda Supinto, Pedro Azmi, Fadhillah bah, Yasavati Kurnia Damanik, Dennys Paulus Parlindungan Daniel Ardian Soeselo Darius Andana, Darius Deli Diny Eldy, Eldy Erandaru Erandaru Fadrul, Fadrul Ferbian Milas Siswanto Flora Rumiati Fortino, Edbert Gabriella Susanto, Nadya Gunawan Gunawan Hanes Hanes, Hanes Hardi, Nicholas Hartanto, Markus Christian Hartanto, Tommy Tiara Holanda, Stevanny Ida Ayu Putu Sri Widnyani Indriani Kurniadi Sumadikarya Inneke Kusumawati Susanto Itanza, Vionita Jeanny Pragantha Jessica Kurnia Niaga, Karmenia Joe, Sherly Khesi, Khesi Lestari, Wulan Sri Lim, Jeksen Listia Natadjaja Lubis, Abdul Rahman Mahariska, Dina Fitria Mahatmaputra, Samuel Marcel Antoni Maria Dara Novi Handayani, Maria Dara Novi Marlim, Yulvia Nora Marpaung, Fenny Krisna Maryanie Maryanie, Maryanie Maryati Maryati Mawaddah Harahap, Mawaddah Melvin Octorian, Melvin Musa, Sulaiman Nababan, Darsono Narulita, Pety Ngantung, Denny Nialindawaty, Nialindawaty Nicholas Renaldo Pakpahan, Cennikon Paulus Paulus Permata, Erwin Pertiwi, Junita Maja Pradnyaswari, Ida Ayu Ketut Andriyogi Priadi, Dina Puspita Purba, Tiurniari Purnasari, Nina Rahmadanty, Nadiya Kamila Rickie, Rickie Rizal Tumewah Rumawas, Marina Astrid S. Sugiharto Salim, Kevin Kristanto Saputra, Vandi Sari, Ike Rukmana Satriabudi, Mirza Indrajanti Selina. Ng, Selina. Ng Sihombing, Josua Parulian Simanjuntak, Demak Claudia Yosephine Stefhanny, Stefhanny Suharyani, Sally Sulia Sulia Tanojo, Tjahjo Djojo Tarigan, Purnaya Sari Telaumbanua, Syahputra Teny Handhayani Tham, Felix Tumboimbela, Melke Tya Wildana Hapsari Lubis Utomo, Natasha Susanto Wahid, Nabila Wariki, Windy M. V. Wijaya, Alvin Wilda Susanti Yo, Rivan Yuda Turana