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All Journal Paediatrica Indonesiana Pharmaceutical Sciences and Research (PSR) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Evy Yunihastuti
Departemen Ilmu Penyakit Dalam FK Universitas Indonesia-RSUP Nasional Dr. Cipto Mangunkusumo
Health Professions Medicine & Pharmacology

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Vaccination for Inflammatory Bowel Disease Patients Yunihastuti, Evy
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.772 KB) | DOI: 10.24871/231202252-61

Abstract

Inflammatory bowel disease (IBD) patients have an increased rate of some vaccine-preventable infection during their course of disease. However, the coverage of vaccination is still low. Many physicians often do not feel comfortable or confidence offering vaccination to IBD patients. Vaccine effectiveness can be altered by the immune dysregulation condition and immunosuppressive therapy that IBD patients use. There are also some concerns about IBD flare after vaccination and potential adverse events related to live vaccines. Nonetheless, offering vaccines and obtaining vaccination history is necessary for health care maintenance of IBD patients, especially those using immunosuppressive therapy.
Association between Food Specific IgG Antibodies with Clinical Activity of Disease in Patients with Inflammatory Bowel Disease Parhusip, Santi Sumihar Rumondang; Rengganis, Iris; Simadibrata, Marcellus; Abdullah, Murdani; Shatri, Hamzah; Yunihastuti, Evy; Wibowo, Heri
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/241202341-48

Abstract

Background: Inflammatory bowel disease (IBD) is an autoimmune disease that is influenced by food, an important factor in accelerating its clinical disease activity because of intestinal inflammation trough formation of antigen-antibody complex. Food-specific IgG examination can identify the types of person foods consumes that are maybe responsible for disease activity. It is useful in treating IBD without risking malnourishment as it is tailored to the individual immune profile.Method: This is a cross-sectional study involving 113 patients diagnosed with IBD by colonoscopy. Examination of serum IgG specific for 220 types of foods was performed using ELISA and immuno-array techniques. Disease clinical activity was assessed using the Mayo index and Crohn's disease activity index.Results: The highest proportion of dietary IgG in Crohn's disease was peas (100%), barley (97.9%), eggs (95.9%), milk (81.6%), and corn (75.5%); while in ulcerative colitis it was barley (98.4%), peas (96.8%), egg whites (92.2%), corn (82.8%), and prunes (78.1%). In ulcerative colitis, there was a weak negative correlation between cashew nuts IgG (r = -0.347; p = 0.041) and chickpeas IgG (r = -0.473; p = 0.017) with clinical disease activity; while in Crohn's disease, a weak positive correlation with disease activity was seen in barley (r = 0.261; p = 0.042).Conclusion: There was a weak negative correlation between cashew and chickpea-specific IgG antibodies with clinical activity of ulcerative colitis, and a weak positive correlation between barley-specific IgG antibodies and Crohn's disease clinical activity. 
Co-Authors . Andriansjah Achmad Fauzy, Achmad Ade Rosanti Adik Wibowo Adityo Susilo, Adityo Agnes Kurniawan Alvina Widhani, Alvina Amal C Sjaaf Andri Sanityoso Sulaiman Angga Pramudita Anggraini Alam Anggriani, Yusi Anna Rozaliyani Anna Ujainah Anna Ujainah, Anna Annisa, Firda Annisa, Rifka Ari F Syam Ari Fahrial Syam Arya Govinda Roosheroe Arya Govinda Roosheroe, Arya Govinda Astrid Citra Padmita Astrid Citra Padmita, Astrid Citra Bambang Sutopo Bramantya Wicaksana Budiman Bela C. Martin Rumende, C. Martin Ceva W. Pitoyo Chandra, Natasha Christy Efiyanti Chyntia Olivia Maurine Jasirwan, Chyntia Olivia Maurine Chyntia Olivia MJ Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cynthia Olivia Maurine Jasirwan Daldiyono Daldiyono Daldiyono Daldiyono Desi Salwani, Desi Dewi Mira Ratih Dewi Rizki Agustina Dewi Rizki Agustina, Dewi Rizki Dewi Sumaryani Soemarko Dhaneswara Adhyatama Wicaksono Djoerban, Zubair Dyah Purnamasari Dyah Purnamasari E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edwin Wijaya Edwin Wijaya, Edwin Elita, Dina Em Yunir, Em Erni J Nelwan, Erni J Erni Juwita Nelwan, Erni Juwita Esthika Dewiasty Esthika Dewiasty, Esthika Estie Puspitasari Estie Puspitasari, Estie F Witjaksono F Witjaksono, F Faisal, Edward Farid Kurniawan Farid Kurniawan, Farid Firda Annisa Gita Aprilicia Gurmeet Singh Gurmeet Singh H.M. Sjaifoellah Noer Hapsari, Aljira Fitya Harimurti, Kuntjro Harinda, Fadlika Hasan Maulahela, Hasan Heri Wibowo Herikurniawan Herikurniawan Herikurniawan, Herikurniawan Herqutanto - Ikhwan Rinaldi Iris Rengganis Iris Rengganis Irsan Hasan Jasirwan, Chyntia Olivia Murine Jasirwan, Chyntia OM Julius R Samban Karmel Tambunan Ken Ayu Mastini Ken Ayu Mastini, Ken Ayu Khie Chen Kuntjoro Harimurti Kurniawan, Juferdy Kurniawan L A Lesmana Leonard Nainggolan Lestari, Regina Maksum, Maradewi Maradewi Maksum Marcellus Simadibrata Maruhum B.H. Marbun Masnjoer, Arif Mira Yulianti Mira Yulianti, Mira Mondrowinduro, Prionggo Murdani Abdullah Murdani Abdullah Nababan, Saut Horas Nasir, Ujainah Zaini Natali, Veritea Nia Kurniati Noto Dwimartutie Nugroho, Pringgodidgo Nur Ainun Nur Ainun Pane, Meivina Ramadhani Parhusip, Santi Sumihar Rumondang Pramita Gayatri Praptini, Mirna Nurasri Pratama, Metra Adi Prima Yuriandro Prima Yuriandro Pringgodigdo Nugroho Pringgodigdo Nugroho, Pringgodigdo Ratih, Dewi Mira Ratu Ratih Kusumayanti Ratu Ratih Kusumayanti Regina Lestari Reise Manninda Rifka Annisa Rino A Gani Rino A Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Robert Sinto Robert Sinto Rosanti, Ade Rudi Putranto Sabrina Munggarani Yusuf Samsuridjal Djauzi Samsuridjal Djauzi Samsuridjal Djauzi Siti Taqwa Fitria Lubis, Siti Taqwa Fitria Sri Wahdini Sukamto Koesnoe Sukamto Koesnoe Sulaiman, Andri Andri Syahrani, Aisyah Teguh Harjono Karjadi, Teguh Harjono Tito Ardi Ujainah Zaini Nasir Unggul Budihusodo Wicaksana, Bramantya Widayat Djoko Santoso Widayat Djoko Santoso, Widayat Djoko Wiraguna, Andrian Yulia Trisna Yulia Trisna, Yulia Yulidar Yulidar Yulidar Yulidar Yusi Anggriani Zakiudin Munasir Zubairi Djoerban Zubairi Djoerban Zubairi Djoerban