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All Journal Paediatrica Indonesiana Pharmaceutical Sciences and Research (PSR) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Evy Yunihastuti
Departemen Ilmu Penyakit Dalam FK Universitas Indonesia-RSUP Nasional Dr. Cipto Mangunkusumo
Health Professions Medicine & Pharmacology

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Vaccination for Inflammatory Bowel Disease Patients Yunihastuti, Evy
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (414.772 KB) | DOI: 10.24871/231202252-61

Abstract

Inflammatory bowel disease (IBD) patients have an increased rate of some vaccine-preventable infection during their course of disease. However, the coverage of vaccination is still low. Many physicians often do not feel comfortable or confidence offering vaccination to IBD patients. Vaccine effectiveness can be altered by the immune dysregulation condition and immunosuppressive therapy that IBD patients use. There are also some concerns about IBD flare after vaccination and potential adverse events related to live vaccines. Nonetheless, offering vaccines and obtaining vaccination history is necessary for health care maintenance of IBD patients, especially those using immunosuppressive therapy.
Association between Food Specific IgG Antibodies with Clinical Activity of Disease in Patients with Inflammatory Bowel Disease Parhusip, Santi Sumihar Rumondang; Rengganis, Iris; Simadibrata, Marcellus; Abdullah, Murdani; Shatri, Hamzah; Yunihastuti, Evy; Wibowo, Heri
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/241202341-48

Abstract

Background: Inflammatory bowel disease (IBD) is an autoimmune disease that is influenced by food, an important factor in accelerating its clinical disease activity because of intestinal inflammation trough formation of antigen-antibody complex. Food-specific IgG examination can identify the types of person foods consumes that are maybe responsible for disease activity. It is useful in treating IBD without risking malnourishment as it is tailored to the individual immune profile.Method: This is a cross-sectional study involving 113 patients diagnosed with IBD by colonoscopy. Examination of serum IgG specific for 220 types of foods was performed using ELISA and immuno-array techniques. Disease clinical activity was assessed using the Mayo index and Crohn's disease activity index.Results: The highest proportion of dietary IgG in Crohn's disease was peas (100%), barley (97.9%), eggs (95.9%), milk (81.6%), and corn (75.5%); while in ulcerative colitis it was barley (98.4%), peas (96.8%), egg whites (92.2%), corn (82.8%), and prunes (78.1%). In ulcerative colitis, there was a weak negative correlation between cashew nuts IgG (r = -0.347; p = 0.041) and chickpeas IgG (r = -0.473; p = 0.017) with clinical disease activity; while in Crohn's disease, a weak positive correlation with disease activity was seen in barley (r = 0.261; p = 0.042).Conclusion: There was a weak negative correlation between cashew and chickpea-specific IgG antibodies with clinical activity of ulcerative colitis, and a weak positive correlation between barley-specific IgG antibodies and Crohn's disease clinical activity. 
Faktor Prediktif Post Dialysis Fatigue Sedang pada Pasien yang Menjalani Hemodialisis Reguler Amu, Ivan Virnanda; Marbun, Maruhum Bonar H; Nugroho, Pringgodigdo; Rinaldi, Ikhwan; Shatri, Hamzah; Mardiana, Nunuk; Hidayat, Rudy; Susalit, Endang; Yunihastuti, Evy; Purnamasari, Dyah; Wardoyo, Elizabeth Y
Jurnal Penyakit Dalam Indonesia
Publisher : UI Scholars Hub

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Abstract

Introduction. Fatigue is often found in patients with CKD-HD. Fatigue serves as an indicator of mortality and may be a viable target in a treatment strategy. Current research has not established the determinants of moderate PDF in individuals with CKD who are undergoing HD. Therefore, this study was conducted to prove the predictor factors of moderate PDF. Methods. A retrospective cohort study in CKD-HD patients at Fatmawati Central General Hospital during the period of November-December 2024. The independent variables of this study are comorbidities, MIS, depression, intradialytic SBPV, dialysis vintage, UFG, IDWG, and anemia status. Primary data from the PDF Scale, MIS, and BDI II questionnaire were collected through patient interviews during the eighth hemodialysis session. Demographic and clinical information of the patients was obtained from medical records. Intradialytic SBPV was determined by the ARV. All variables were examined using the chi-square test, except for the depression variable, which failed to fulfil the requirements and was assessed using the Fisher exact test. A logistic regression analysis was performed to identify the most significant association among the predictor variables of moderate PDF. Results. A total of 135 research subjects were included in the study. Based on the results of the bivariate analysis, MIS, depression, and the type of dialysis were significantly linked to moderate post dialysis fatigue (p < 0.05). From the results of the multivariate analysis, inflammatory malnutrition (RR 1.580; 95% CI 1.017–2.455; p = 0.042), dialysis vintage (RR 1.850; 95% CI 1.208–2.834; p = 0.005), and depression (RR 2.165; 95% CI 1.542–3.039; p < 0.001) were obtained. The logistic regression model shows a significant relationship between moderate PDF and severe malnutrition inflammation score, mild to moderate depression, and dialysis vintage exceeding 12 months. Conclusion. Our findings underscore a significant association between depression, dialysis vintage, and malnutrition inflammation score (MIS) with moderate PDF in CKD-HD patients.
Co-Authors . Andriansjah Achmad Fauzy, Achmad Ade Rosanti Adik Wibowo Adityo Susilo, Adityo Agnes Kurniawan Alvina Widhani, Alvina Amal C Sjaaf Andri Sanityoso Sulaiman Angga Pramudita Anggraini Alam Anggriani, Yusi Anna Rozaliyani Anna Ujainah Anna Ujainah, Anna Annisa, Firda Annisa, Rifka Ari F Syam Ari Fahrial Syam Arya Govinda Roosheroe Arya Govinda Roosheroe, Arya Govinda Astrid Citra Padmita Astrid Citra Padmita, Astrid Citra Bambang Sutopo Bramantya Wicaksana Budiman Bela C. Martin Rumende, C. Martin Ceva W. Pitoyo Chandra, Natasha Christy Efiyanti Chyntia Olivia Maurine Jasirwan, Chyntia Olivia Maurine Chyntia Olivia MJ Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cynthia Olivia Maurine Jasirwan Daldiyono Daldiyono Daldiyono Daldiyono Desi Salwani, Desi Dewi Mira Ratih Dewi Rizki Agustina Dewi Rizki Agustina, Dewi Rizki Dewi Sumaryani Soemarko Dhaneswara Adhyatama Wicaksono Djoerban, Zubair Dyah Purnamasari Dyah Purnamasari E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edwin Wijaya Edwin Wijaya, Edwin Elita, Dina Em Yunir, Em Endang Susalit Erni J Nelwan, Erni J Erni Juwita Nelwan, Erni Juwita Esthika Dewiasty Esthika Dewiasty, Esthika Estie Puspitasari Estie Puspitasari, Estie F Witjaksono F Witjaksono, F Faisal, Edward Farid Kurniawan Farid Kurniawan, Farid Firda Annisa Gita Aprilicia Gurmeet Singh H.M. Sjaifoellah Noer Hapsari, Aljira Fitya Harimurti, Kuntjro Harinda, Fadlika Hasan Maulahela Heri Wibowo Herikurniawan Herikurniawan Herikurniawan, Herikurniawan Herqutanto - Ikhwan Rinaldi Iris Rengganis Iris Rengganis Irsan Hasan Jasirwan, Chyntia Olivia Murine Jasirwan, Chyntia OM Julius R Samban Karmel Tambunan Ken Ayu Mastini Ken Ayu Mastini, Ken Ayu Khie Chen Kuntjoro Harimurti Kurniawan, Juferdy Kurniawan L A Lesmana Leonard Nainggolan Lestari, Regina Maksum, Maradewi Maradewi Maksum Marcellus Simadibrata Maruhum B.H. Marbun Masnjoer, Arif Mira Yulianti Mira Yulianti, Mira Mondrowinduro, Prionggo Murdani Abdullah Murdani Abdullah Nababan, Saut Horas Nasir, Ujainah Zaini Natali, Veritea Nia Kurniati Noto Dwimartutie Nugroho, Pringgodidgo Nunuk Mardiana, Nunuk Nur Ainun Nur Ainun Pane, Meivina Ramadhani Parhusip, Santi Sumihar Rumondang Pramita Gayatri Praptini, Mirna Nurasri Pratama, Metra Adi Prima Yuriandro Prima Yuriandro Pringgodigdo Nugroho Pringgodigdo Nugroho, Pringgodigdo Ratih, Dewi Mira Ratu Ratih Kusumayanti Ratu Ratih Kusumayanti Regina Lestari Reise Manninda Rifka Annisa Rino A Gani Rino A Gani Rino Alvani Gani Rino Alvani Gani Rino Alvani Gani Robert Sinto Robert Sinto Rosanti, Ade Rudi Putranto Rudy Hidayat Sabrina Munggarani Yusuf Samsuridjal Djauzi Samsuridjal Djauzi Samsuridjal Djauzi Siti Taqwa Fitria Lubis, Siti Taqwa Fitria Sri Wahdini Sukamto Koesnoe Sukamto Koesnoe Sulaiman, Andri Andri Syahrani, Aisyah Teguh Harjono Karjadi, Teguh Harjono Tito Ardi Ujainah Zaini Nasir Unggul Budihusodo Virnanda Amu, Ivan Wardoyo, Elizabeth Y Wicaksana, Bramantya Widayat Djoko Santoso Widayat Djoko Santoso, Widayat Djoko Wiraguna, Andrian Yulia Trisna Yulia Trisna, Yulia Yulidar Yulidar Yulidar Yulidar Yusi Anggriani Zakiudin Munasir Zubairi Djoerban Zubairi Djoerban Zubairi Djoerban