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All Journal Journal of Islamic Pharmacy Biomedical Journal of Indonesia Turbo : Jurnal Program Studi Teknik Mesin AL-ATHFAAL : JURNAL ILMIAH PENDIDIKAN ANAK USIA DINI Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) SEIKO : Journal of Management & Business JURISMA: Jurnal Riset Bisnis & Manajemen JOURNAL OF SPORT EDUCATION (JOPE) Magistra Andalusia : Jurnal Ilmu Sastra Jurnal Bina Desa Jurnal Nagara Bhakti: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Jurnal Abdimastek (Pengabdian Masyarakat Berbasis Teknologi) Jurnal Geosaintek Geoid - Journal of Geodesy and Geomatics
Yuwono Yuwono
Fakultas Hukum Universitas Udayana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences Transportation Other

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Journal : Biomedical Journal of Indonesia

 1 
COMPARISON BETWEEN BELUNTAS (PLUCHEA INDICA LEES) FRACTION AND KETOCONAZOLE INVITRO ON CANDIDA ALBICANS Marsasi, Bina; Yuwono, Yuwono; Salni, Salni
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7974

Abstract

Beluntas leaves are useful as a treatment for flour albus and discharge caused by fungi. This study aims to find the anti-fungal activity of fraction of beluntas (Pluchea indica Lees) leaf extract against Candida albicans. This research is an in vitro experimental study using the Posttest-only Control Group Design study design. Methanol extract is obtained through maceration process while the fraction is through liquid-liquid fractionation. The most active fraction is determined by the antifungal activity test. The most active fractions with concentrations of 10%, 5%, 2.5%, 1.25%, 0.625% and the diameter of the inhibition zone 0.3125% were measured by the liquid dilution method. Equivalence with drugs is assessed through regression analysis, then the class of active compounds is determined through bioautographic testing using thin layer chromatography. The research results obtained methanol-fraction-water can inhibit the growth of Candida albicans while the methanol extract, n-hexane and ethyl acetate do not inhibit. The methanol fraction of water which has inhibition zone diameters starts at a concentration of 0.3125% with an average diameter of 7.34 mm and at a concentration of 10% the largest diameter of 17.10 mm is obtained. Through the diluent liquid and the KHM solid fraction from the methanol-water fraction is inhibited at a concentration of 0.3125%. Equivalence test shows that 1 mg / ml of ketoconazole is equivalent to 39,561 mg / ml of methanol-water fraction of beluntas leaves. Compounds that inhibit fungi are thought to be active groups of flavonoid and alkaloid compounds. The methanol-water fraction of beluntas leaves (Pluchea indica Lees) has antifungal activity against Candida albicans in vitro.
RELATIONSHIP OF SNP (RS867500) STX1A EXON 10 GENE WITH INTELLECTUAL INTELLIGENCE LEVEL Qur'andini, Dalinur; Yuwono, Yuwono; Triwani, Triwani
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7975

Abstract

The purpose of this study was to determine the relationship of SNP (rs867500) on the STX1A Exon 10 gene with the level of intellectual intelligence. This study was an observational analytic study with a cross sectional study design with a population of 368 and a sample of 36 which was divided into two groups, namely the above average IQ group and the average IQ group. To find out the relationship of SNP (rs867500) STX1A Exon 10 gene with intelligence level used X2 test (Chi-square). The results showed no SNPs were found in the STX1A exon 10 gene. The STX1A gene can be said to contribute to intelligence along with other genes, namely IGFR2 and FNBPL1 genes, although there is no polymorphism in the exon 10 STX1A gene.
Co-Authors Aan Eka Pranata Jaya, Aan Eka Pranata Abdul Hakim Adi Kurniawan Aditya, Farhan Qashidi Affandi, Abdi Rachmad Agung Budi Cahyono Ahmad Taufik Aji Tri Pamungkas Akbar Kurniawan Al-Azhar, Muhammad Ilham Fahmi Alfa Budi Setiawan Yunior Anies Setiowati, Anies Anjasmara , Ira Mutiara Ariani, Reni Arisudhana, Dicky Ariyani S, Dian Asroni Asroni Asroni, Asroni Awang Irawan, Fajar Azzumardi , Ilham Alfin Baary , Ery Abdul Barata, Fausta Ari Budi Doyo, Budi Budi Swastomo Budisusanto , Yanto Cahya, Doni Muslim Chuang, Long-Ren Dhias Fajar Widya Permana Edhie Budi Setiawan, Eduard Alfian Syamsya Sijabat, Dian Artanti Arubusman, Eko Yuli Handoko Elizabeth Yohanes Faisal, Nazib Fajar Awang Irawan Fierman Sjafirial Agustus Filaili , Ragfinsa Budiaski Frangky Silitonga Genena, Rhaisang Al Iman Taufiqul Hakim Hidayat, Ravindra Safitra Hillman, Ben Proyogo I Made Dwifa Satya Nugraha, I Made Dwifa Satya Indah Rahayu Lestari Iswati, Heni Khoiril Anam, Khoiril Khomsin Khomsin, Khomsin Kurniawan, Dedy Lailatul Qhomariyah, Lailatul Laksmiwati, Mia Lulus Baktiyaningsih Mardiana, Ninik Marsasi, Bina Martono, Dwi Budi Moh Gema Perkasa Drakel, Moh Gema Perkasa Mulyono, Yulita Eka Rana Murtadlo, Mohammad Luay Novrizal, Yudhi Nurjannah Nurjannah Nurtjahyono, Nurtjahyono Pebriadi , Ali Permadi , Kukuh Danu Prasetya, Rizky Eka Prasetyo, Bambang Agung Pratomo, Danar Guruh Pribadi , Cherie Bhekti Pusparini, Dewi Okta Puspita, Ruri Putu Angga Bujana, Putu Angga Qur'andini, Dalinur Rahman , Alfian Sukri Rahmayunita, Deasy Rosyida Rakhmatsyah, Benyamin Rinny Meidiyustiani Rizal Sanif Rudianto, Roedy Rustham Basyar, Rustham Saleh, Agustria Z Salni Sastradinata, Irawan Setyarko, Yugi Sidad, Balya Farras Sindi Mandasari, Sindi Siregar, Paulina Slamet Asnawi Su'udi, Firdaus Amirullah Subarsyah Subarsyah Sugeng Priyanto, Sugeng Sulaiha, Fiamanati Supadiningsih, Chatarina Nurjati Supriyadi, Agung Supriyono, Tjatur Surono, Bambang Sutaryono Syarifuddin Syarifuddin Tri Cahyo Wahyudi Triwani Triwani Tulloh, M. Ubayu Rizqi Rohmat Udiana Wahyu Deviantari, Udiana Wahyu Umam, Syukron Khotibul Wahyudi, Tri Cahyo Wibowo, Aufa Khoironi Tuba Yen Yen Ari Indrawijaya Yuniani, Emi