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All Journal Journal of Islamic Pharmacy MNJ (Malang Neurology Journal) Majalah Obstetri dan Ginekologi JIEET (Journal of Information Engineering and Educational Technology) Pharmaceutical Journal of Indonesia Majalah Kedokteran Neurosains JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Indian Journal of Forensic Medicine & Toxicology Cermin Dunia Kedokteran AKSONA Indonesian Journal of Cancer Neurona Cermin Dunia Kedokteran
Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo******
Department Of Neurology, Faculty Of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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BEKAM SEBAGAI TERAPI ALTERNATIF UNTUK NYERI Hanik Badriyah Hidayati; Mohammad Hasan Machfoed; Kuntoro Kuntoro; Soetojo Soetojo; Budi Santoso; Suroto Suroto; Budi Utomo
NEURONA Vol 36 No 2 (2019)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v36i2.69

Abstract

      CUPPING AS PAIN ALTERNATIVE THERAPYABSTRACTPain is still a world’s problem. Current pain treatment is still unsatisfactory due to its chronicity and existing drugs’ side effects. Due to dissatisfaction with the existing treatment, many patients are choosing a traditional therapy for their pain treatment. Cupping therapy is one of the traditional therapies that is widely used to relieve pain. Cupping therapy has been used in many countries in the world. Some of these countries have used cupping therapy as a pain treatment in hospitals. Neurologists are handling pain cases in their daily practice. Nearly 80% of patients come to the doctor with one of their complaint related to pain directly. The knowledge of cupping therapy for pain is important for the development of new therapies in order to solve the pain problems that so far have not reached a satisfactory level.Keyword: Alternative therapy, cupping therapy, pain, pain problemsABSTRAKNyeri masih merupakan masalah dunia. Pengobatan nyeri saat ini masih belum sampai tahap yang memuaskan terkait kronisitas dan efek samping obat yang ada. Akibat ketidakpuasan dengan pengobatan yang ada, banyak pasien yang memilih terapi tradisional untuk pengobatan nyerinya. Terapi bekam merupakan salah satu terapi tradisional yang banyak dipakai untuk meredakan keluhan nyeri. Terapi bekam telah dipakai di banyak negara di dunia. Sebagian negara tersebut telah menggunakan bekam sebagai terapi nyeri di rumah sakit. Bekam menurunkan nyeri melalui efek antinosiseptifnya, dengan cara stimulasi sistem saraf perifer dan menurunkan stres oksidatif. Studi terbaru menunjukkan bahwa terapi bekam basah dapat meningkatkan ekspresi ß-endorphin dan HSP70 keratinosit pada lokasi bekam. Dalam praktek sehari-hari dokter spesialis saraf menangani kasus nyeri. Hampir 80% pasien datang ke dokter dengan disertai salah satu keluhan yang berkaitan dengan nyeri secara langsung. Pengetahuan tentang terapi bekam untuk nyeri penting diketahui untuk pengembangan terapi baru guna menyelesaikan permasalahan nyeri yang sampai saat ini belum sampai pada tahap yang memuaskan.Kata kunci: Masalah nyeri, nyeri, terapi alternatif, terapi bekam  
MANIFESTASI NEUROPSIKIATRIK PADA LUPUS ERITEMATOSUS SISTEMIK DI RSUD DR. SOETOMO SURABAYA Nadya Rinda Eka Rana; Awalia Awaliah; Yetti Hernaningsih; Hanik Badriyah Hidayati
NEURONA Vol 36 No 4 (2019)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v36i4.88

Abstract

    NEUROPSYCHIATRIC MANIFESTATION AMONG SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS IN GENERAL HOSPITAL SURABAYAABSTRACTIntroduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with unknown causes and extensive clinical manifestations and diverse disease pathways. The clinical manifestations of SLE are very diverse, including the involvement of the nervous system and psychiatric syndrome (neuropsychiatric).Aims: To describe clinical neuropsychiatric manifestations of   patients with SLE in Soetomo General Hospital Surabaya.Methods: This was a cross-sectional study based on medical record data on all SLE patients treated at Dr. Soetomo Hospital Surabaya, from January-December 2017. Neuropsychiatric manifestations assessment were based on the nomenclature of the American College of Rheumatology (ACR) in 1999.Results: There were 49 patients, mostly women (98%) with mean age 30,8±10,2 years old. Neurological manifestation was the 3rd  most common diagnosis (43%) after hematologic disorder (73.5%) arthritis (53.1%). The manifestations of neuropsychiatric manifestation were mainly seizures (40.8%), headache (34.7%), cerebrovascular disease (26.5%), acute confusional state (20.4%), cognitive dysfunction (6.1%), and polyneuropathy (8.2%).Discussion: The most common neuropsychiatric clinical features in SLE patients are seizures, headache, cerebrovascular disease, and acute confusional state.Keywords: Lupus neuropsychiatry, prevalence, systemic lupus erythematosusABSTRAKPendahuluan: Lupus eritematosus sistemik (LES) merupakan penyakit inflamasi autoimun kronik yang belum diketahui penyebabnya dengan perjalanan penyakit yang luas. Manifestasi klinis LES sangat beragam, antara lain keterlibatan sistem saraf dan sindrom psikiatri (neuropsikiatri).Tujuan: Untuk mengetahui manifestasi neuropsikiatrik pasien dengan LES di RSUD Dr. Soetomo, Surabaya.Metodologi: Penelitian potong lintang berdasarkan data rekam medik terhadap semua pasien LES yang dirawat di RSUD Dr. Soetomo, Surabaya, pada bulan Januari hingga Desember 2017. Manifestasi neuropsikiatrik dinilain berdasarkan nomenklatur American College of Rheumatology (ACR) tahun 1999.Hasil: Didapatkan 49 subjek yang hampir semuanya (98%) adalah perempuan dengan rerata usia 30,8±10,2 tahun. Gangguan neurologis merupakan ketiga tersering (43%) setelah gangguan hematologi (73,5%) dan artritis (53,1%). Manifestasi neuropsikiatri terutama kejang (40,8%), nyeri kepala (34,7%), penyakit serebrovaskular (26,5%), keadaan konfusi akut (20,4%), dan polineuropati (8,2%).Diskusi: Manifestasi klinis neuropsikiatri yang paling banyak dialami oleh pasien LES adalah kejang, nyeri kepala, penyakit serebrovaskular, dan keadaan konfusi akut.Kata kunci: Lupus eritematosus sistemik, manifestasi klinis, neuropsikiatri  
HUBUNGAN FAKTOR SOSIODEMOGRAFI TERHADAP SKOR QUALITY OF LIFE IN EPILEPSY INVENTORY-10 PASIEN EPILEPSI DEWASA DI RSUD DR. SOETOMO Dwiastri Iris Sarwastuti; Paulus Sugianto; Hanik Badriyah Hidayati; Azimatul Karimah
NEURONA Vol 38 No 3 (2021)
Publisher : PERDOSNI

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Abstract

Introduction: Several socio-demographic factors, such as age, sex, marital status, level of education, and employment status can determine adult epilepsy patients’ quality of life, which Quality of Life quantitively presents in Epilepsy Inventory-10 (QOLIE-10) score. Aim: This study was to understand the correlation between age, sex, marital status, level of education, and employment status on adult epilepsy patients’ QOLIE-10 score at Soetomo General Hospital. Methods: Analytical observational study using accidental sampling of adult epilepsy patients at Soetomo General Hospital in June 2019-December 2019 was implemented. Several socio-demographic factors were obtained, including age, sex, marital status, level of education, employment status, and their QOLIE-10 score calculation. Correlation analysis against the QOLIE-10 score was carried out, including the Spearman test for socio-demographic factors of age and level of education; and the Mann-Whitney test for socio-demographic factors of gender and marital status, and employment status. Results: Obtained a total of 47 samples with the most common characteristics such as aged 18-25 years (29.8%), male (53.2%), married (57.4%), had the last educational level in senior high school (68.1%), and unemployed (68.1%). Correlation analysis showed an insignificant relationship between age, sex, marital status, recent education, and employment status on the QOLIE-10 score of adult epilepsy patients (p≥0.05). Discussion: Age, sex, marital status, recent education, and employment status did not show a significant relationship to the QOLIE-10 score of adult epilepsy patients. Keywords: epilepsy, QOLIE-10
Profiles of Patients with Low Back Pain Caused by Disc Herniation in the Neurology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya during the Period of 2021 Agindra, Bani; Hidayati, Hanik Badriyah; Widhiyanto, Lukas; Herawati, Lilik
AKSONA Vol. 4 No. 2 (2024): JULY 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v4i2.52778

Abstract

Highlight: The degenerative process plays a dual role, both protecting from and causing disc herniation. Men have a quicker degeneration rate at a younger age, while women have a quicker rate at an older age. Occupational factors such as physical workload, repetition, bending, and sitting periods all contribute to disc herniation.   ABSTRACT Introduction: Low back pain (LBP) refers to a sensation of pain or discomfort occurring in the region between the lowest costal and gluteal crease, with or without leg pain. Damage to the annulus fibrosus causes disc herniation, allowing the nucleus pulposus to herniate into the spinal canal. In less than 5% of cases, LBP is caused by disc herniation. Objective: This study examined the profiles of individuals with herniated LBP discs and related factors at Dr. Soetomo General Academic Hospital Surabaya. Methods: The study was conducted at Dr. Soetomo General Academic Hospital Surabaya using secondary data from medical records, which was then analyzed using descriptive statistics. Results: Fifty-eight LBP patients with herniated discs were enrolled in this study. The patient sample ranged from 23 to 74 years old, with a mean of 47,98±14,92. The majority of patients (29.3%) were 31–40 years old. Male and female prevalence rates were the same. Employees have the highest percentage of any occupation group, with 56.9%. Conclusion: Some of the findings clarify previous studies. Age, gender, and occupation were all linked to the occurrence of either LBP or disc herniation. However, our data cannot indicate whether or not these factors contribute to the occurrence of LBP and disc herniation. Therefore, more research is required to understand these factors and their relation to disc herniation and LBP.  
Peran Diabetes Melitus pada Gejala Klinis Osteoartritis Lutut Riska Puspasari; Hanik Badriyah Hidayati
Cermin Dunia Kedokteran Vol 47 No 4 (2020): Interna
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i4.369

Abstract

Osteoartritis (OA) adalah penyakit sendi degeneratif kronik progresif yang umum dan menyebabkan gangguan mobilitas sendi, sehingga membatasi aktivitas sehari-hari. Hiperglikemia kronik pada DM diduga dapat meningkatkan peradangan sendi dan degradasi kartilago yang meningkatkan risiko kejadian OA dan progresivitasnya. Hasil observasi pada pasien OA lutut di unit rawat jalan saraf RSUD Dr Soetomo Surabaya menunjukkan pasien OA lutut dengan intensitas berat lebih banyak pada penderita DM. Osteoarthritis (OA) of the knee is a common degenerative joint disease which limits daily activities. Many studies suggest a significant relationship between diabetes mellitus (DM) and OA. Chronic hyperglycemia in DM is suspected to increase joint inflammation and cartilage degradation which increases the risk of OA events and their progression. Observations in the neurological outpatient unit of Dr. Soetomo Public Hospital Surabaya showed that worse knee OA were more likely to develop among DM patients.
Headache in Preeclampsia: Review Article Sumbawati, Mulia Dian; Hidayati, Hanik Badriyah; Ernawati, Ernawati
AKSONA Vol. 5 No. 2 (2025): JULY 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v5i2.53273

Abstract

Highlight: Headache in preeclampsia is classified as a type of secodary headache. Pregnant women with high blood pressure have a 17-fold increased risk of developing secondary headaches. Typical preeclampsia-related headaches are progressive, bilateral (frontal or occipital), throbbing, associated with visual abnormalities, getting worse with elevated blood pressure or exercise, and resistant to over-the-counter drugs..   ABSTRACT Preeclampsia is a multisystem vascular disease characterized by systemic disturbances in maternal endothelial function and symptoms such as arterial hypertension and organ dysfunction, including the kidneys, liver, and brain. A headache is defined as pain or discomfort localized in the head region. Pregnancy-related headaches may have primary causes, such as migraines, but they can also indicate potentially life-threatening secondary causes, including preeclampsia. Pregnant women with high blood pressure have a 17-fold increased risk of developing secondary headaches. Headaches associated with preeclampsia can adversely affect pregnancy and labor, increasing the risk of complications. Preeclampsia headaches can predict eclampsia or seizures 56% sensitivity and 83% specificity. According to research conducted in Indonesia, the majority of preeclampsia patients experienced severe headaches (65.2%), followed by moderate (19.6%), mild (13%), and no headaches (2.2%). Therefore, based on the existing literature, this article intends to compile scientific data on headache pain in preeclampsia patients.  
Retrospective Analysis of Numerical Pain Rating Scale (NPRS) Scores in Diabetic Neuropathy Patients Receiving Gabapentin and Non-Gabapentin Therapies at an Indonesian Tertiary Hospital Novianto, Rifky Alif; Hidayati, Hanik Badriyah; Novida, Hermina; Bodová, Klára
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 2 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i2.66470

Abstract

Introduction: Diabetic neuropathy is a common complication of diabetes, affecting over half of patients and frequently leading to diabetic neuropathic pain (DNP), which can be difficult to treat. Gabapentin is commonly used as a first-line therapy for DNP and works by modifying calcium channels to reduce pain. This study aimed to evaluate and compare Numerical Pain Rating Scale (NPRS) profiles in DNP patients receiving gabapentin and non-gabapentin therapies at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Methods: This retrospective study analyzed the medical records of 24 DNP patients at Dr. Soetomo General Academic Hospital from January to December 2023. The inclusion criteria comprised patients diagnosed with diabetic neuropathy, according to the International Statistical Classification of Diseases, Tenth Revision (ICD-10) code E11.4, and treated for pain using gabapentin and/or other therapies. Patients with incomplete records or unrelated neuropathic conditions were excluded. The data encompassed NPRS scores, demographics, diabetes mellitus duration, pain characteristics, drug types, doses, and therapy durations. Results: Among 24 patients, the majority were female (54.1%) and over 60 years old (58.3%), with a diabetes duration of 6–10 years (54.1%). Tingling was the most frequently observed symptom (75%). Gabapentin administered as monotherapy (1×300 mg) was the predominant treatment (56.5%) and provided the greatest reduction in NPRS scores (7 points) after 4–12 weeks. Combination therapies showed smaller reductions. Conclusion: Gabapentin used as monotherapy is effective for managing DNP, especially over 4–12 weeks. Patients with long-standing diabetes, particularly older adults, are the most affected and benefit from targeted therapy.   Highlights: 1. This study evaluates the demographic, clinical, and therapeutic profiles of patients with diabetic neuropathic pain, focusing on gabapentin and non-gabapentin therapies.2. Novel insights into the distribution of therapies and numerical pain rating scale (NPRS) scores among patients offer a foundation for optimizing pain management strategies.3. This research contributes to identifying patterns in drug efficacy and therapy duration, particularly with the administration of gabapentin for managing diabetic neuropathic pain.
Clinical Symptoms of Patients with Early-Stage and Advanced-Stage Ovarian Cancer Shofwana, Haura Almash Aulia; Hidayati, Hanik Badriyah; Saraswati, Wita; Tjokroprawiro, Brahmana Askandar
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1134

Abstract

Background: Ovarian cancer is a malignant neoplasm originating from ovarian cells with different histological types depending on the subtype. It can affect women of all ages. Ovarian cancer ranks third in terms of incidence among diagnosed female cancer patients, following breast and cervical cancer. Ovarian cancer often doesn’t present specific/clear symptoms. As a result, only a small number of patients are diagnosed at an early stage (20%). The study aimed to analyze the clinical complaints experienced by ovarian cancer patients, both in early and advanced stages before diagnosis. Methods: This descriptive cross-sectional study analyzes clinical complaints before the diagnosis of early and advanced-stage ovarian cancer patients. The study was conducted in the Gynecology-Oncology inpatient ward at Dr. Soetomo Regional General Hospital in 2021, utilizing medical record data. Results: A total of 98 patients (21 patients with early-stage, and 77 patients with advanced-stage) were analyzed. The majority of the patients are aged 45-58 years (49%), work as homemakers (32.7%), and are married (63.3%). The three most common complaints experienced by subjects with early-stage ovarian cancer were abdominal/pelvic pain (23.8%), abdominal/pelvic pressure (28.6%), and abdominal distension (42.9%), while in patients with advanced-stage ovarian cancer were abdominal/ pelvic pain (32.7%), abdominal distension (42.9%), and abdominal discomfort (bloating, early satiety, feeling of fullness, frequent belching, heartburn, nausea and vomiting) (44.2%). Conclusions: The three most common clinical complaints among patients before being diagnosed with early and advanced-stage ovarian cancer in the inpatient ward of Dr. Soetomo Regional General Hospital Surabaya in 2021 were similar. The recognition of these complaints and several risk factors are expected to assist in the earlier diagnosis of ovarian cancer.
Co-Authors Abdurachman Abdurachman Agindra, Bani Agus Prihanto Aisyah Shabrina Alia, Safia Amelia, Elena Ghentilis Fitri Arinda Putri Auna Vanadia Askandar Tjokroprawiro Atika atika Aulia Rachma Nur Azizah Awalia Awaliah Azzahra, Zahwa Arsy Bodová, Klára Budi Santoso Budi Utomo Chrismawan Ardianto Dwiastri Iris Sarwastuti Elena Ghentilis Fitri Amelia Endah Purwanti Ernawati Ernawati Ernawati, Iin Fahmi Achmad Faisal Fahmi, Achmad Fitri Amelia, Elena Ghentilis Hapsari Peni Agustin Tjahyaningtijas HERAWATI, LILIK Hermina Novida, Hermina I'tishom, Reny Ilmanita, Dzikrina Imami, Nabilah Hasna Indri Wahyuni Intan Indah Permatasari IRWANTO Junaidi Khotib Jusak Nugraha Karimah, Azimatul Kuntoro Kuntoro Kuntoro Kuntoro Lely Retno W Lukas Widhiyanto Machin, Abdulloh Martono Tri Utomo Mohammad Hasan Machfoed Mohammad Hasan Machfoed Muhammad Hamdan Muhammad Hamdan Nabilah Hasna Imami Nadya Rinda Eka Rana Naim Rochmawati Nila Kurniasari Novianto, Rifky Alif Nugraha, Priya Paulus Sugianto Prastiya Indra Gunawan Priya Nugraha Puspasari, Riska Rahayu Nofita Sari Rehatta, Nancy Margarita Rejeki, Purwo Sri Riska Puspasari Riska Puspasari Rivarti, Arina Windri Rozalina Loebis, Rozalina Safia Alia Sensusiati, Anggraini Dwi Setianti, Ariani Rahayu Shofwana, Haura Almash Aulia Siti Khaerunnisa Soetojo Soetojo Suhartati Suhartati SUMARNO Sumbawati, Mulia Dian Suroto Suroto Susi Wahyuning Asih Tamara Audrey Kadarusman Turchan, Agus WITA SARASWATI, WITA Wiyli Yustanti Yetti Hernaningsih YUNI YAMASARI