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Analisis Tingkat Pengetahuan dan Perilaku Swamedikasi Diare terhadap Mahasiswa Farmasi Universitas Tanjungpura: Knowledge and Behaviour Assessment of Diarrhea Self-Medication among Pharmacy Undergraduate in Tanjungpura University Agvina Felicia Esperanza; Liza Pratiwi; Shoma Rizkifani
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1277

Abstract

Self-medication is done to treat minor illnesses, such as diarrhea. Knowledge and behaviour of drugs usage in each individual affect self-medication so that irrational drugs usage can be prevent. This study determines the relationship between semester, knowledge and behaviour about diarrhea self-medication of pharmacy students at Tanjungpura University 2021/2022. The research method was carried out retrospectively in the form of a cross-sectioned questionnaire. Stratified random sampling method was used for sample selection. Rank-spearman analysis was used to analyze the relationship between semester level, knowledge and behaviour of diarrhea self-medication. Based on research, out of 232 respondents, majority of respondents were women, aged 21, obtained drugs from pharmacies without prescription (81,03%) and used adsorbent class for antidiarrheal drugs. Knowledges are classified from good (9,91%), moderate (28,45%) and low (61,64%). Behaviours are classified as appropiate (79,74%) and inappropriate (20,26%). The p-value results show the relationship between semester and knowledge 0,142; relationship between semester and behaviour 0,256 and relationship between knowledge and behaviour 0,318. The conclusion of this study is the relationship between semester and knowledge are categoried very low with positive significant relationship. Relationship between semester and behaviour and relationship between knowledge and behaviour are categoried low with positive significant relationship. Keywords: behaviour, diarrhea, knowledge, self-medication Abstrak Swamedikasi dilakukan untuk mengatasi keluhan atau penyakit ringan seperti penyakit diare. Tingkat pengetahuan dan perilaku individu dalam penentuan dan penggunaan obat diare dapat mempengaruhi swamedikasi diare sehingga tidak terjadi penggunaan obat yang tidak rasional. Penelitian ini bertujuan mengetahui hubungan tingkat semester, pengetahuan dan perilaku mahasiswa farmasi Universitas Tanjungpura tahun 2021/2022 terhadap swamedikasi diare. Metode penelitian dilakukan secara retrospektif potong lintang berbentuk kuesioner. Metode stratified random sampling digunakan untuk pemilihan sampel. Analisis rank-spearman digunakan untuk menganalisis hubungan tingkat semester, pengetahuan dan perilaku responden terhadap swamedikasi diare. Berdasarkan penelitian menunjukkan bahwa dari 232 responden, mayoritas responden adalah perempuan, berusia 21 tahun, memperoleh obat dari apotek tanpa resep (81,03%), dan menggunakan obat diare golongan adsorben. Responden memiliki tingkat pengetahuan yang baik (9,91%), cukup (28,45%) dan kurang (61,64%) dan tingkat perilaku tepat (79,74%) dan tidak tepat (20,26%). Hasil p-value menunjukkan hubungan tingkat semester terhadap pengetahuan yaitu 0,142; hubungan tingkat semester terhadap perilaku 0,256 dan hubungan tingkat pengetahuan dan perilaku 0,318. Kesimpulan dari penelitian ini adalah terdapat hubungan signifikan positif berkategorikan sangat rendah pada tingkat semester terhadap pengetahuan dan hubungan signifikan positif berkategorikan rendah pada tingkat semester terhadap perilaku dan hubungan tingkat pengetahuan terhadap perilaku berkategorikan rendah. Kata Kunci: diare, pengetahuan, perilaku, swamedikasi
EFEKTIVITAS EKSTRAK ETANOL DAN EKSTRAK KLOROFORM SIPUT ONCHIDID (Onchidium thyphae) SEBAGAI PENUMBUH RAMBUT PADA TIKUS (Rattus norvegicus) Wijianto, Bambang; Wijianto, Bambang Wijianto; Pratiwi, liza; Utami, Amanda Yanasari
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/fba2x720

Abstract

Hair loss is a problem that can affect appearance. A natural ingredient that can address hair loss treatment is the extract of the onchidiid snail. This study aims to test the hair growth effectiveness of ethanol and chloroform extracts of the onchidiid snail on white rats (Rattus norvegicus). The test groups of rats were divided into several groups: the Negative Group (CN), the Positive Group (CP) with candlenut oil, Treatment Group I (K1) with Chloroform Extract of the Onchidiid Snail, and Treatment Group II (K2) with Ethanol Extract of the Onchidiid Snail. Hair growth length was measured daily and processed using Image J software. The hair growth effectiveness test showed that over 14 days, the chloroform extract (K1) produced faster results compared to the other three groups, with a hair growth result of 1.61 cm on the 14th day. The findings of this study conclude that the chloroform extract of the onchidiid snail effectively promotes hair growth in male Wistar strain white rats.
Pelatihan Pembuatan Nano Liquid Aromaterapi bagi Kader PKK Desa Wajok Hilir di Kabupaten Mempawah: Training on Manufacturing Aromatherapy Nano liquid for PKK Cadres in Wajok Hilir Village in Mempawah District Pratiwi, Liza; Wijianto, Bambang; Fahrurroji, Andhi; Yuswar, Muhammad Akib
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 3 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i3.6251

Abstract

So far, essential oils have only been used as perfume and sold as raw material. On average, residents of Wajok Hilir village have yards covered with essential oil-producing plants such as lavender, lemongrass, and coconut. The aim of the PKM Program is training in utilizing community resources to make essential oils for aromatherapy in nano-liquid preparations. The development of this product must be oriented towards developing a practice that is easy to apply and environmentally friendly without ignoring environmental health. The solution to overcome existing problems is to provide knowledge to partners about the benefits of nano liquid preparations as aromatherapy and mosquito repellent and training on using essential oils as aromatherapy. Pharmacists provided training on making "nano liquid" products. This training activity will involve PKK cadres from Wajok Hilir village. The output target of this activity is to increase the level of quality empowerment of partners by driving sustainable activity programs from product results. This service activity showed that the 31 participants comprised the majority of women and homemakers, 77.4% with a high school education level. The results of measuring participants' knowledge and skills showed an increase in the pre-test and post-test scores, which were 55.5 and 78.33, respectively. In conclusion, the service activities that have been carried out have increased the knowledge and abilities of participants regarding the use of essential oils as aromatherapy in the form of nano-liquid preparations.
FORMULATION OF FACE PACK POWDER USING SIMPLEX LATTICE DESIGN METHOD Fitri, Aulia Kemala; Pratiwi, Liza; Nurbaeti, Siti Nani
Journal Pharmacy Of Tanjungpura Vol 1, No 2 (2024): APRIL
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Face pack powder is a cosmetic preparation that has been developed in the pharmaceutical industry. In powder dosage formulations, the important components used are binders. This study aimed to obtain an optimal formulation of face pack powder with a combination of binders. The binders combined in this study were carbopol, hydroxypropyl methylcellulose (HPMC), and sodium carboxymethyl cellulose (CMC-Na). The binder combination in the formula was predicted with simplex lattice design (SLD) mehod of Design-Expert ® software. The applied method for making the face pack powder was wet granulation based on 13 runs of software with responses in the form of pH and moisture content. The results showed that the pH of the preparations was in the range of 5.2-6.3 and that the water content was 1.54-2.87%. The pH and water content data were then entered into the software to obtain the optimum composition with a carbopol : HPMC : CMC-Na ratio of 3:1:1. The optimum formulation of the face pack powder is with white color, smooth texture, vanilla scent, pH 5.4, and 1.64% moisture content. The optimum formula data was then analyzed using one-sample t-test to verify that the predicted formula and the experimental results do not differ significantly (p0.05) so that it could be used to design the optimum formula
Formulasi NLC-Stick Ekstrak Bunga Telang (Clitoria ternatea L.) Dengan Variasi Konsentrasi Shea Butter dan Asam Stearat Damanik, Virna Helena; Pratiwi, Liza; Wijianto, Bambang
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 1 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i1.16719

Abstract

NLC of telang flower extract has an effect as a sunscreen to protect the skin from sunlight. Stick preparation in NLC formulation can facilitate the use of sunscreen. This study aims to determine and compare variations in the concentration of Shea Butter (as a Base) and stearic acid (as a Harding Agent) and obtain the results of physical evaluation of variations in the concentration of Shea butter and Stearic Acid. NLCs of telang flower extract were formulated into formulas with varying concentrations of shea butter and stearic acid in the ratio of 80:20; 50:50; 20:80. Furthermore, the physical properties of NLC-Stick of bay flower extract were evaluated, including organoleptic test, homogeneity test, pH test, melting time test, and spreadability test. The results showed that the optimal variation of shea butter and stearic acid concentration was 50:50. The optimum formula of NLC-Stick of telang flower extract has a colour like the active substance, solid shape, soft aroma, homogeneous, pH of 4.56 ± 0.3, melting time test of 21 minutes, and spreadability test of 3 cm. NLC-Stick with varying concentrations of shea butter:stearic acid (50:50) has a physical evaluation that meets the stick requirements.
Optimization of Gel Cream Containing HAMIN™ and HPMC K100M as Bases for Topical Delivery of Diclofenac Sodium Lina Winarti; Amirah Mohd Gazzali; Fania Mufti Mufidah; Fahrauk Faramayuda; Evi Umayah Ulfa; Dwi Nurahmanto; Muhammad Hilmi Afthoni; Liza Pratiwi; Bambang Wijianto
Borneo Journal of Pharmacy Vol. 9 No. 1 (2026): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v9i1.10417

Abstract

Diclofenac sodium, a widely used NSAID, has limited skin permeability, which reduces its topical efficacy; therefore, a gel-cream formulation combining the rapid absorption of gels with the emollient properties of creams is proposed to enhance drug penetration and patient comfort. To further improve delivery, HAMIN™, a novel natural palm oil–based base with excellent biocompatibility and lipid-enhancing properties, will be combined with HPMC K100M. This thickener stabilises viscosity and prolongs skin contact time, supporting better absorption. This study aimed to develop and optimise a topical gel cream for diclofenac sodium using HAMIN™ and HPMC K100M to achieve ideal physical properties and improved skin penetration. The formulation was statistically optimised using a Simplex Lattice Design (SLD), with HAMIN™ (X1) and HPMC K100M (X2) as independent variables, and pH (Y1), spreadability (Y2), viscosity (Y3), extrudability (Y4), release flux (Y5), and permeation flux (Y6) as dependent responses. Optimisation with Design Expert version 13 yielded the ideal composition of 16.84% HAMIN™ and 1.16% HPMC K100M, resulting in predicted values of pH 5.07, spreadability 7 cm, viscosity 4502.25 mPas, extrudability 78.98 N/s, release flux 70.61 µg/cm2/minute, and permeation flux 0.4868 µg/cm2/minute, with a desirability score of 0.829. Despite a slightly lower release flux, the optimised HAMIN™ and HPMC K100M-based gel cream demonstrated superior skin permeation compared to a commercial emulgel for up to 300 minutes. The incorporation of HAMIN™, a natural palm oil base, offers a novel and effective strategy to enhance the topical delivery of diclofenac sodium via a statistically optimised gel cream formulation.
The Effectiveness Assay of Healing Incutions of Nanostructured Lipid Carriers (NLCS) Ethanol Extract of Moringa Leaf (Moringa oleifera) on White Rats (Rattus norvegicus) Bambang Wijianto; Liza Pratiwi
Al-Kauniyah: Jurnal Biologi Vol. 19 No. 2 (2026): AL-KAUNIYAH: JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v19i2.43051

Abstract

Wounds are disruptions of tissue integrity that impair normal physiological function. Nanostructured Lipid Carriers (NLCs) are lipid-based nanosystems that enhance the delivery of bioactive compounds. Moringa oleifera leaves contain bioactive constituents, including isothiocyanates and cytokinins (zeatin), which exhibit antibacterial activity and promote cell proliferation, potentially accelerating wound healing. This study aimed to evaluate the wound-healing effectiveness of NLCs containing Moringa oleifera leaf ethanol extract. An acute open-incision wound model was established in rats, divided into five groups: normal control, betadine ointment (positive control), NLC base (negative control), extract gel, and NLCs containing 5% Moringa oleifera leaf ethanol extract. Treatments were applied topically, and wound healing was monitored by measuring wound area reduction with ImageJ. The percentage of wound closure and area under the curve (AUC) values were calculated and analyzed using one-way ANOVA. Both the extract gel and NLC formulations accelerated wound healing compared with the positive and negative controls. Complete wound closure was achieved on day 8 in the treatment groups, whereas the positive and negative controls reached complete closure on days 10 and 14, respectively. These findings indicate that NLCs containing Moringa oleifera leaf ethanol extract have potential as an effective topical formulation for promoting wound healing.
Pemberdayaan Siswa SMK Bina Dharma Melalui Pembuatan Serbuk Effervescent sebagai Produk Kesehatan Berbasis Etnofarmasi: Empowering Bina Dharma Vocational School Students Through the Production of Effervescent Powder as an Etnopharmacy-Based Health Product Liza Pratiwi; Bambang Wijianto; Muhammad Akib Yuswar; Muhammad Nur Ajwad; Fakhruddin Fakhruddin
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 11 No. 5 (2026): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v11i5.11413

Abstract

Vocational education that combines theory and practice has been proven to be effective in improving students' skills, particularly in preparing them for the challenges of the working world. This study aims to evaluate the effectiveness of the materials and practices used in the production of effervescent moringa powder on students' understanding at SMK Bina Dharma Pratama. The research design used was quasi-experimental with a one-group pretest-posttest design. The study began with a pre-test to assess students' initial knowledge, followed by the provision of materials and practical training in the production of effervescent moringa powder. After the activities, the students were given a posttest to measure their increased understanding. The study's results showed an average score increase from 53.75 (pre-test) to 63.75 (post-test), or approximately 18.6%. This increase indicates a significant learning gain. Despite variations in student results, this finding suggests that practice-based learning can enhance students' technical skills and conceptual understanding in pharmacy. This study contributes to the development of educational methods that integrate theory and practice to enhance students' practical skills and to the implementation of experiential education in vocational training.
TINGKAT PENGETAHUAN MAHASISWA PROGRAM STUDI FARMASI FAKULTAS KEDOKTERAN UNIVERSITAS TANJUNGPURA TENTANG SUN PROTECTION FACTOR PADA SUNSCREEN DALAM PEMILIHAN DAN PENGGUNAAN SUNSCREEN Kapitarauw, Juliana Marta; Susanti, Ressi; Pratiwi, Liza
Journal Pharmacy Of Tanjungpura Vol. 3 No. 2 (2026)
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Paparan radiasi UV yang berasal dari sinar matahari dapat mengakibatkan kerusakan pada sel-sel kulit serta memicu kerusakan DNA yang meningkatkan resiko terjadinya kanker kulit. Sehingga diperlukan proteksi tambahan baik secara fisik dan kimia yaitu dengan menggunakan Tabir Surya (sunscreen). Efisiensi perlindungan sunscreen terhadap paparan radiasi sinar UV di tentukan oleh Sun Protection Factor (SPF) yang menunjukan berapa lama sunscreen dapat melindungi kulit dari paparan sinar matahari. Penelitian ini bertujuan untuk menganalisis tingkat pengetahuan tentang SPF dan mengkaji faktor yang mempengaruhi pemilihan dan penggunaan sunscreen pada Mahasiswa Program Studi Farmasi Fakultas Kedokteran Universitas Tanjungpura. Metode yang digunakan pada penelitian ini adalah probability sampling dengan teknik simple random sampling. Pengumpulan data dilakukan melalui kuesioner dalam bentuk google form dengan total responden 191 orang. Berdasarkan hasil yang diperoleh tingkat pengetahuan Mahasiswa tergolong baik dengan presentase sebesar 85%. Dalam pemilihan dan penggunaan sunscreen 74% mahasiswa memilih sunscreen berdasarkan jenis sunscreen, 69% berdasarkan nilai SPF, 50% berdasarkan iklan TV dan media social, 50% berdasarkan rekomendasi keluarga dan teman, serta 54% berdasarkan rekomendasi celebrity/influencer. Diketahui mahasiswa program studi farmasi paling banyak memilih sunscreen berdasarkan jenis sunscreen yakni physical dan chemical. Kata Kunci : Sunscreen, Pengetahuan, Sun Protection Factor
Nanostructured Lipid Carriers Combinated of Green Coffee (Coffea arabica L.) and Kelulut Honey Design Liza Pratiwi; Any Guntarti
Majalah Obat Tradisional Vol 31, No 2 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.101247

Abstract

Nanostructured Lipid Carriers (NLCs) have great potential as pharmaceuticals and cosmetics. Bioactive compounds in Coffea arabica L. include chlorogenic acid and its derivatives, caffeine, theophylline and theobromine, cafestol, kahweol, tocopherol and trigonelline. The contents of Heterotrigona itama are flavonoids, phenolic acids, proteins, amino acids, ascorbic acid, hydroxy methyl furfuraldehyde (HMF), and enzymes. This research aimed to formulate coffee and honey extracts using a targeted delivery system for topical use on the skin. The research method begins with the extraction process using ethanol solvent's maceration method. NLCs formulate by design expert for lipid, surfactant, and cosurfactant variation were evaluated for transmittance, pH, entrapment efficiency, particle size, transmission electron microscope (TEM), stability, and in vitro activity with DPPH. Based on the evaluation, the optimal NLCs obtained combined (glyceryl monostearate: tocopherol oil): tween 20: (PEG 400: propylenglikol) with a 4.27:24.02:13.71 composition ratio. The optimal NLCs green coffee and kelulut honey extract formulation for transmittance value was 96.98% ± 0.67, pH was 5.26 ± 0.19, and entrapment efficiency was 99.99 % ± 0,00,  particle size was 225 nm ± 0.39, and TEM provided details. Evaluation for antioxidant in vitro, IC50 NLCs optimal formula 72,12 ± 1,24; extract without NLCs 72.59 ± 0.79; and NLCs of base without extract 379.17 ± 2.05. The stability evaluation shows NLCs green coffee and honey extract stable in real-time stability and freeze-thaw cycle. NLCs green coffee and honey extract that was formulated by Design-Expert software has physical characteristics according to requirements, stable, and had antioxidant activity.