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All Journal Jurnal Kedokteran Syiah Kuala Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Althea Medical Journal Jurnal Berkala Epidemiologi Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Jurnal NERS Indonesian Journal of Tropical and Infectious Disease Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal Science and Technology Indonesia Journal Of Vocational Health Studies Amerta Nutrition JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology Medicosphere Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Erwin Astha Triyono
Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Medicosphere

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Factors That Reduce The Incidence of Lung Tuberculosis Other Than Isoniazid Preventive Therapy (IPT) in Latent Igra Positive HIV-TB Patients Shinta Karina Yuniati; Tutik Kusmiati; Erwin Astha Triyono; Aryati
Journal of Diverse Medical Research: Medicosphere Vol. 1 No. 4 (2024): J Divers Med Res 2024
Publisher : Faculty of Medical - UPN Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i4.20

Abstract

Background. One crucial public health measure to stop persons living with HIV (PLWHA) from developing active TB is isoniazid preventative therapy (IPT). Only few hospitals in Indonesia continue to offer IPT. Aim. The purpose of this study was to assess how IPT affected the incidence of TB in patients with latent HIV infection. Method. This study uses a prospective cohort design and is quasi-experimental in design. Samples for the study were obtained by convenience sampling and the study was carried out in the inpatient and outpatient departments of UPIPI Dr. Soetomo Hospital. Latent IGRA positive HIV-TB patients who satisfied the inclusion requirements made up the samples. Result. Of the 59 patients who finished the screening exam, 23 fulfilled the inclusion requirements for this study. Using the ELISPOT method, the IGRA T-SPOT.TB test yields 36 (64.29%) negative findings and 23 (35.18%) positive results. After six months of IPT administration, analysis of the data revealed that the incidence of active pulmonary TB in latent HIV-TB patients was 0% in the IPT group and 0% in the non-IPT group. Antiretroviral medication used for more than four years and a CD4+ T lymphocyte count of more than 200 cells/μL were factors that contributed to the lack of pulmonary tuberculosis in both groups. Conclusion. ARV used for more than four years and CD4+ lymphocyte count more than 200 cells/L contributing significantly in pulmonary tuberculosis incidence.
Co-Authors Afif Nurul Hidayati Alfadhila Khairil Sinatrya Amos Pongbulaan Anak Agung Ayu Niti Wedayani Anindita Abigail Anisa Lailatul Fitria Aprilawati, Dwi Arini, Merita Armedy Ronny Hasugian Aryati Aryati Aryati Aryati Aryati Audrey Gracelia Riwu Bambang Wiryanto Bramantono Bramantono, Bramantono Brian Eka Rahman Budiono Budiono Christian Yochanan Christina Avanti Cita Rosita Sigit Prakoeswa Djoko Agus Purwanto Djoni Susanto Dwi Murtiastutik Eddy Bagus Wasito Endang Retnowati Endang Retnowati Endang Wahyu Fitriani Erika Marfiani Erna Kristin Eti Nurwening Sholikhah Eva Lydiawati Faiz Murfid Gunawan Feriawan Tan Firdausa, Sarah Firdausiyah Firdausiyah Hafidh Maulana Harianah Harianah Hazreen B Abdul Majid Hermi Indita I Made Sila Darmana Intan Putri Risky Amalia Iskandar Zulkarnain Ivan Hoesada James Hutagalung Jaya, Halim Priyahau JS. Hutagalung Jusak Nugraha Kartikadewi, Indriani Kartikawati, Tri Kartina, Leny kawilarang, Arthur pohan Kusmiati, Tutik Kusumayanti, A.A.Ayu Mas Linda Astari, Linda M Vitanata M. Yulianto Listiawan Mahdian, Haidar Masyfufah, Lilis Muhammad Amin Musofa Rusli MVS Mahanani Nabil Salim Ambar Nabilah Nono Tri Nugroho Noor Idha Handajani Novanda, Aisyah Wahyu Nurohmawati, Weni Oryza Dwi Nanda Pambudi, Rien Esti Pauline Hadisiswoyo Pudji Lestari R. Heru Prasetyo R. Heru Prasetyo Rachmad, Eka Basuki Rahmadewi Rahmadewi Ramadhani, Putri Nabilah Rehatta, Nancy Margarita Rimbun Rimbun Rohiman, Abu Senda Sulvain Rahmaningrat Shinta Karina Yuniati Siti Rahayu Nadhiroh Siti Surdijati, Siti Sulistiawati Sulistiawati Sulvy Dwi Anggraini Syahru Ramadhaan Unzila Tan, Feriawan Tripudi Asmarawati Umiastuti, Pirlina Usman Hadi Usman Hadi Wahyu Dian Pratiwi Wahyunitisari, Manik Retno Widjaja, Sajuni