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All Journal Majalah Obat Tradisional Sistemasi: Jurnal Sistem Informasi JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Cendekia Journal of Pharmacy Jurnal Abdidas Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Abdimas Kartika Wijayakusuma ABDINE Jurnal Pengabdian Masyarakat Jurnal Lentera Jurnal Ilmiah Pengabdian dan Inovasi Jurnal Kesehatan Farmasi Karimah Tauhid Parapemikir Jurnal Ilmiah Farmasi BIOCITY: Journal of Pharmacy Bioscience and Clinical Community Indonesian Journal of Health Research Innovation Jurnal Kesehatan Qamarul Huda
Fitri Apriliany, Fitri
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Sensitivity of Bacteria causing Hospital-Acquired Pneumonia (HAP) in the Intensive Care Unit (ICU) to Empiric Antibiotics APRILIANY, FITRI; Umboro, Recta Olivia; Ersalena, Vera Fitriya; Setiawan, Deni; Cholisah, Elis
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.565

Abstract

The main therapy for the treatment of pneumonia is antibiotics. The use of antibiotics requires special attention to prevent antibiotic resistance. Therefore, it is important to know the pathogenic microorganisms that cause hospital-acquired pneumonia (HAP) infections. This study aimed to describe the sensitivity of negative-positive bacteria to empiric antibiotics in HAP patients. The study method was an analytical descriptive observational study with a cross-sectional design. Data were collected from patient medical records for the period January 2019 – December 2020. Inclusion criteria were ICU patients diagnosed with HAP, aged 15 years, with complete medical records (age, sputum culture, leukocytes, chest x-ray results), treatment history and outcome parameters (vital signs). Exclusion criteria were pregnant patients, involuntary discharge, and ICU stay of less than 48 hours. The data in this study were analyzed descriptively and Likelihood Ratio. The results of the description showed that the empiric antibiotics with sensitivity more than 70% against gram-positive bacteria causing HAP were rifampin (78%), TMP-sulfamethoxazole (78%), vancomycin (100%), and linezolid (100%) while the empiric antibiotics with sensitivity more than 70% against gram-negative bacteria was cefoperazone-sulbactam (≥75%), followed amikacin and imipenem (≥55%). Meanwhile, the empiric antibiotics had a very low sensitivity (≤ 50%) against ESLB-producing bacteria and MRSA. There is a significant relationship between age and educational level factors and bacterial growth in sputum cultures (p<0.05). Conclusion: Vancomycin and linezolid are sensitive to gram-positive bacteria, cefoperazone-sulbactam is sensitive to gram-negative bacteria and resistance to ESLB-producing bacteria and MRSA has occurred.
Hubungan Kejadian Gastritis dengan Riwayat Penggunaan Obat Anti Inflamasi Non Steroid (OAINS) pada Pasien yang Melakukan Pemeriksaan Endoskopi Nirmala Putri, Kintan Nandini; Apriliany, Fitri; Ramdhany, Muh. Wisda Praja
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol. 2 No. 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3319

Abstract

Gastritis is inflammation of the gastric mucosa, one of which is caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs). It is very common that NSAIDs are used to treat pain, fever, and inflammatory processes. This study aims to examine the relationship between the incidence of gastritis and a history of NSAIDs use. The research method use in this study is a retrospective cohort design of which the data is collected through interview of patients and their families. The patients medical records at the Mataram City Regional Hospital was also collected. Testing was carried out using the Pearson Correlation test. The result shows that gastritis patients were dominated by people aged 36-55 years (46.43%) and 49 of them were female (58.33%). The Pearson Correlation test shows no significant relationship between the incidence of gastritis and a history of NSAID use, with a p-value> 0.05 and an r-value < 1. This indicates a weak relationship between gastritis and the use of NSAIDs. Therefore, the history of NSAIDs use is insignificant as the main reason for gastritis. Gastritis can also be caused by other factors such as age, lifestyle, and stress levels.
Pengaruh Reminding melalui Whatsapp Terhadap Kepatuhan Minum Obat pada Pasien Tuberkulosis Paru Saputra, Yovi Agus; Apriliany, Fitri; Ramdhany, Muh. Wisda Praja
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol. 2 No. 2 (2024): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v2i2.3320

Abstract

Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. M. tuberculosis enters the body through inhaled air and spreads in the lungs. In 2021, Mataram City detected a total of 739 tuberculosis cases. Many tuberculosis patients still exhibit low adherence to taking their medication. This research investigates the influence of WhatsApp reminders on medication adherence in pulmonary tuberculosis patients. This is an analytical observational study with a quasi-experimental design that employs a prospective pre-test and post-test approach. The data for this study was collected from outpatient patients at RSUD Kota Mataram. The result indicates a significant improvement in medication adherence among pulmonary tuberculosis patients, with a significant value of the Wilcoxon test (p = 0.000, <0.05). The conclusion drawn from this study is that reminders through WhatsApp influence medication adherence in pulmonary tuberculosis patients at RSUD Kota Mataram.
Aktivitas Antifungi Ekstrak Etanol Daun Parsley (Petroselinum Crispum) Terhadap Pertumbuhan Jamur Candida Albicans Secara Invitro Bimmaharyanto S., Dedent Eka; Umboro, Recta Olivia; Apriliany, Fitri
Jurnal Kesehatan Qamarul Huda Vol. 10 No. 2 (2022): Desember 2022
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/jkqh.v10i2.2022.411

Abstract

Candida albicans merupakan flora normal didalam tubuh manusia. Mikroorganisme  spesies jamur dari golongan deuteromycota ini pada kondisi tertentu dapat bersifat pathogen. Spesies ini adalah salah satu penyebab infeksi oportunistik kandidiasis pada kulit, mulut, organ kelamin. Parsley (Petroselinum crispum) merupakan tanaman aromatik berkhasiat obat. Kandungan senyawa flavanoid pada tanaman ini memiliki khasiat sebagai antifungi. Penelitian ini bertujuan untuk melihat efektivitas dan konsentrasi minimal ekstrak etanol daun parsley (Petroselinum crispum) dalam menghambat pertumbuhan  Candida albicans. Uji aktivitas antifungi dilakukan dengan metode disc diffusion test, menggunakan sampel uji ekstrak etanol 70% daun parsley (Petroselinum crispum) dengan konsentrasi 10%; 30%; 50%; 80% dan 100% (b/V). Kontrol positif menggunakan nystatin 100.000 IU dan kontrol negatif menggunakan aquadest steril. Hasil pengamatan dianalisis secara diskriptif dan diuji menggunakan analisisn statistik ANOVA Kruskal wallis. Hasil penelitian menunjukkan bahwa ekstrak etanol 70% daun parsley (Petroselinum crispum) signifikan efektif menghambat pertumbuhan Candida albicans. Konsentrasi 100% memiliki efek setara dengan kontrol positif. Sedangkan konsentrasi minimum yang mampu menghambat pertumbuhan Candida albicans adalah sebesar 10%.
Uji Invitro Aktivitas Mukolitik Ekstrak Etanol 70% Daun Lamtoro (Leucaena leucocephala (Lam) de Wit) Eka Bimmaharyanto S., Dedent; Umboro, Recta Olivia; Apriliany, Fitri
Jurnal Kesehatan Qamarul Huda Vol. 11 No. 1 (2023): Juni 2023
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/jkqh.v11i1.2023.485

Abstract

Daun lamtoro (Leucaena leucocephala (Lam) de Wit) secara tradisional telah digunakan masyarakat Indonesia sebagai obat batuk. Khasiat mukolitik daun lamtoro diduga dipengaruhi oleh senyawa saponin dan tanin. Penelitian ini bertujuan untuk mengetahui efek mukolitik dan konsentrasi efektif ekstrak etanol 70% daun lamtoro (Leucaena leucocephala (Lam) de Wit) secara in vitro. Metode penelitian ini menggunakan Rancangan Acak Lengkap (RAL), yang terdiri dari satu kelompok kontrol negatif (tween 80), kelompok kontrol positif (asetilsistein) dan 4 kelompok perlakuan konsentrasi ekstrak etanol 70% daun lamtoro (Leucaena leucocephala (Lam) de Wit ) sebesar 5%, 10%, 20%, 30% (b/b). Parameter uji berupa nilai viskositas sampel mucus usus sapi. Hasil uji statistik ANOVA-LSD pada kelompok kontrol negatif dengan kelompok perlakuan konsentrasi 10%,20%,30% menunjukkan adanya perbedaan signifikan (P<0.005) sedangkan pada kelompok perlakuan konsentrasi 30% dengan kontrol positif tidak terdapat perbedaan signifikan. Sehingga dapat disimpulkan bahwa ekstrak etanol 70% daun lamtoro (Leucaena leucocephala (Lam) de Wit) memiliki aktivitas mukolitik pada uji invirtro mukus sapi dengan konsentrasi efektif sebesar 30%.
Korelasi Efektifitas Terapi Ceftriaxone Terhadap Outcome Klinis pada Pasien Balita Community Acquired Pneumonia (CAP) ) Apriliany, Fitri; Fanny Dwi Febriyana; Umboro, Recta Olivia; Bimmaharyanto , Dedent Eka
Jurnal Kesehatan Qamarul Huda Vol. 11 No. 2 (2023): Desember 2023
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/jkqh.v11i2.2023.570

Abstract

Masalah kesehatan utama di Indonesia adalah penyakit infeksi. Community acquired pneumonia (CAP) merupakan salah satu penyakit infeksi yang membutuhkan rawat inap di rumah sakit. CAP termasuk urutan ke 3 penyebab kematian balita. Sehingga, pada program pencegahan dan pengendalian ISPA difokuskan pada pengendalian pneumonia pada balita. Tujuan penelitian ini adalah untuk mengetahui korelasi efektifitas terapi antibiotic ceftriaxone terhadap outcome klinis pada pasien balita CAP. Kriteria inklusi penelitian ini adalah pasien balita usia 0-5 tahun, diagnosa CAP dan sedang dirawat inap. Kriteria eksklusi adalah pasien yang memiliki komplikasi penyakit pneumonia dan usia lebih 5 tahun. Data sosio-demografi, gambaran terapi antibiotik CAP digambarkan secara deskriptif dan analisis korelasi efektifitas terapi antibiotik terhadap outcome menggunakan uji Spearrman. Responden pada penelitian ini sebanyak 70 pasien yang didominasi oleh perempuan (53%) dengan usia 0 hari sampai kurang 2 tahun (64%). Jenis terapi yang digunakan adalah ceftriaxone (81,5%), cefixime (1,4%), cefotaxime (7,1%) dan ampicillin (10%). Hasil menunjukkan bahwa terdapat pengaruh ceftriaxone terhadap outcome klinis pasien yang artinya pemberian ceftriaxone efektif dalam mencapai outcome membaik. Selain itu, tingkat keeratan hubungan (korelasi) yang lemah, tanda korelasi positif memiliki makna bahwa kedua variabel memiliki arah hubungan yang berpola searah (p= 0,001, r= 0,395).
Analysis of Clinical Outcomes Based on Demographic Characteristics of Patients with Type 2 Diabetes Mellitus Apriliany, Fitri; Cholisah, Elis; Zainal, Zainol Akbar; Umboro, Recta Olivia
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 14, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.83586

Abstract

Background: Diabetes is one of the top 10 causes of death worldwide. Many factors increase the risk of mortality and morbidity in patients with diabetes such as age, sex, BMI, educational attainment, and marital status.Objectives: The study aimed to analyze clinical outcomes based on patient demographics.Methods: This method was cross-sectional and was conducted at Antapani Medika Clinic, Bandung. Inclusion criteria for this study were diabetic patients who had complete medical records, and who were receiving oral antidiabetic therapy for at least 6 months. Exclusion criteria for study were patients with diabetes who were on insulin therapy, patients with tuberculosis, and pregnant and lactating women. Data on demographic characteristics were analyzed descriptively. Chi-square and likelihood ratio tests were used to analyze differences in clinical outcomes based on therapy achievement on patient demographics.Results: The results showed that HbA1c target levels were achieved by patients who were 65 years of age or older (68%), had a BMI in non-obese category (80.8%), had diabetes for six years or more (80.8%), were married (62.9%), attended college (68.4%), exercised 3 to 6 times per week (64.9%), did not smoke (61.9%), and had no comorbidities (65.3%). This study concludes that there is an association between BMI and duration of diabetes and achievement HbA1c target (p<0.05).Conclusion: The clinical implications of this study are as a guide for health workers in Indonesia in management of diabetes so that they can provide services to patients according to the medical needs of patients.
Hadapi pandemi covid-19 dengan perilaku hidup bersih dan sehat (PHBS) di era new normal Umboro, Recta Olivia; Apriliany, Fitri; Ersalena, Vera Fitriya
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 4 No 3 (2021)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v4i3.10195

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that can be transmitted to humans. The government of West Nusa Tenggara Province confirmed 3.082 positive cases of Covid-19 with 223 cases in Central Lombok by September 2020. Geographically, Penujak is one of villages in Central Lombok close to Lombok International Airport which is an entry point for local and international tourists. Thus, Lecturers of Division of Pharmacy, Bumigora University conducted Community Service Activity entitled “Sosialisasi Hidup Sehat dan Bersih di Tengah Pandemi Covid-19 dan Pelatihan Pembuatan Hand Sanitizer” which aims to educate societies how to start healthy life. The community service was done by socializing for healthy living and adapting to the new normal, and training to formulating hand sanitizer properly. Therefore, new insights and better understanding were gained in order to live healthily and to implement their skills to produce proper standar for hand sanitizer.
ANALISIS TINGKAT KEPARAHAN INTERAKSI OBAT PADA PASIEN COMMUNITY ACQUIRED PNEUMONIA (CAP) DI RSUD PROVINSI NTB Sekar Ningrat, Lalu Nune; Fitri Apriliany; Nurul Indriani
Indonesian Journal of Health Research Innovation Vol. 1 No. 4 (2024): Indonesian Journal of Health Research Innovation
Publisher : Yayasan Menawan Cerdas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64094/q3vjv691

Abstract

Community Acquired Pneumonia (CAP) adalah suatu infeksi peradangan paru-paru yang menyebabkan adanya gangguan fungsi paru. Pasien CAP umumnya diberikan terapi antibiotik dan non-antibiotik. Tujuan penelitian ini yaitu untuk mengetahui hubungan antara tingkat keparahan interaksi obat dengan lama rawat inap pasien Community Acuired Pneumonia (CAP). Penelitian dilakukan secara deskriptif analitik dengan pengamatan dilakukan secara retrospektif dengan pendekatan studi potong lintang (cross sectional). Pengambilan data ini dilakukan dengan mengumpulkan rekam medis pasien CAP di Instalasi Rawat Inap RSUD Provinsi NTB periode januari-november 2023. Hasil yang didapatkan 94 kejadian (13,8 %) dengan tingkat keparahan major, 485 kejadian (71,4 %) dengan tingkat keparahan moderate dan 101 kejadian (14,8 %) dengan tingkat keparahan minor lalu dilakukan uji hipotesis menggunakan uji kolmogorov smirnov didapati hasil p < 0,05. Terdapat hubungan yang signifikan antara tingkat keparahan interaksi obat dan lama rawat inap pasien ditunjukan dengan nilai (p = 0,000)
Uji Validasi dan Reliabilitas Kuesioner SF-36 Versi Bahasa Indonesia untuk Mengukur Kualitas Hidup Pasien Hemodialisa Gagal Ginjal Kronis Indriswari, Baiq; Apriliany, Fitri; Novitarini
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 4 No 1 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v4i1.5841

Abstract

Chronic kidney disease (CKD) not only impacts physiological aspects but also reduces the patient's quality of life. Assessment of the quality of life is important as an indicator of the success of therapy and disease management. This study aims to determine the validity and reliability of the Indonesian version of the Short Form-36 questionnaire in measuring the quality of life of CKD patients undergoing hemodialysis. This study used a descriptive cross-sectional design with a prospective approach. Data were collected by completing the Short Form-36 questionnaire by CKD patients undergoing outpatient care at RSUD Mataram. Validity analysis was performed using Pearson correlation, while reliability was tested with Cronbach's alpha. The number of respondents was 30 patients. The results showed that the Short Form-36 questionnaire had a Pearson correlation value > 0.40 and a Cronbach's alpha value > 0.70, indicating that this instrument is valid and reliable. Thus, the Indonesian version of the Short Form-36 questionnaire can be used to assess the quality of life of CKD patients.
Co-Authors Afni, Zahratul Hayatil Laila Agus syahid Alfiansyah, Muhammad Wisnu Anita Mursiany Anita Mursiany, Anita Baiq Dinda Puspita Ayu Baiq Mahmudah Bimmaharyanto , Dedent Eka Bimmaharyanto S., Dedent Eka Bimmaharyanto, Dedent Eka Cholisah, Elis Dedent Eka Bimmaharyanto S Dedent Eka Bimmaharyanto S. Dedent Eka Bimmaharyanto Sarsono DENI SETIAWAN Distya Riski Hapsari Dwi Monika Ningrum Eka Bimmaharyanto S., Dedent Elis Cholisah Elis Cholisah Erlianti, Karina Fanny Dwi Febriyana Fatimatuzzahra Fatimatuzzahra Fatimatuzzahra Fuzi Maulana Ash'ari Hady Anshory Hasniah Hasniah Hilda Hastuti I Dewa Putu Pramantara I Dewa Putu Pramantara Indriswari, Baiq Iva Rinia Dewi Karina Erlianti M. Zulfikar Al Fariqi Muhammad Rifqi Ni Komang Dewi Anggita Nirmala Putri, Kintan Nandini Novitarini Nurul Indriani Ramdhany, Muh. Wisda Praja Regina Pricilia Yunika Regina Pricilia Yunika Rizki Rahmadi Pratama Saputra, Yovi Agus Sekar Ningrat, Lalu Nune Sri Winarni Sofya Tamhid, Hady Anshory Triana Hertiani Umboro, Recta Olivia Vera Fitriya Ersalena Vera Fitriya Ersalena Vera Fitriya Ersalena Vera Fitriya Ersalena Widani Darma Isasih Zainal, Zainol Akbar Zullies Ikawati