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All Journal Perspektif : Review Penelitian Tanaman Industri Elkawnie Majalah Obat Tradisional Dentino: Jurnal Kedokteran Gigi Journal of Islamic Pharmacy JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Abditani : Jurnal Pengabdian Masyarakat SRIWIJAYA JOURNAL OF MEDICINE Medika Kartika : Jurnal Kedokteran dan Kesehatan Perspektif, Review Penelitian Tanaman Industri Jurnal Buana Farma AJAD : Jurnal Pengabdian kepada Masyarakat Proceeding of Mulawarman Pharmaceuticals Conferences Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Applied Agricultural Science and Technology Room of Civil Society Development Riset Informasi Kesehatan AGRIC kawanad Borneo Journal of Pharmacy Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Room of Civil Social Development Agroscript: Journal of Applied Agricultural Sciences Journal of Pharmascience
Fahrauk Faramayuda, Fahrauk
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : jurnal buana farma

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TINJAUAN LITERATUR: POTENSI TANAMAN OBAT SEBAGAI SUMBER ANTIOKSIDAN ALAMI Faramayuda, Fahrauk; Safrudin, Nurul Safirah; Windyaswari , Ari Sri
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1623

Abstract

Oxidative stress is a major driver of degenerative diseases, while synthetic antioxidants may pose long-term safety risks. The need for safer natural antioxidants has accelerated the exploration of medicinal plants, which are rich in bioactive compounds with antioxidant potential, particularly flavonoids and polyphenols. This systematic review aimed to classify antioxidant compounds from medicinal plants according to their phytochemical groups and to appraise their therapeutic potential based on recent pharmacological evidence. Articles published between 2015 and 2025 were retrieved from PubMed, Google Scholar, Garuda. Fifteen studies met the inclusion criteria for antioxidant activity testing. The review identified dominant antioxidant constituents, classified by chemical structure, including phenols, polyphenols, flavonoids, quercetin, and flavonoid–hydroquinone derivatives, reported across multiple plant species (Table 1). Plants consistently described as antioxidant sources were reundeu (Straurogyne elongata), moringa (Moringa oleifera), Indonesian bay leaf (Eugenia polyantha), water clover (Marsilea crenata), mango leaves (Mangifera indica), raru wood (Cotylelobium lanceolatum), and Jamaican cherry (Muntingia calabura), exhibiting moderate to strong antioxidant activity mainly in DPPH and FRAP assays. Overall, the findings indicate that antioxidant activity correlates with structural features such as the number and position of hydroxyl (–OH) groups, conjugated systems, and metal-chelating capacity. However, these compounds still face challenges related to poor stability and low bioavailability, suggesting that nanotechnology-based delivery systems may enhance formulation effectiveness. In conclusion, the plants reviewed contain promising antioxidant constituents, with quercetin and flavonoids emerging as the most active compounds, supporting their development as candidates for natural antioxidant-based phytopharmaceutical raw materials in Indonesia.
Co-Authors Adella Shindy Pratiwi Adely, Alyaa Muliahati Adinda Fitriani Adriana, Reyhan Akbar, Tzazkia Febriyana Akhirul Kahfi Syam Amedea, Esanda Zulfi Ami Soega Dwigantina Ananda Tunjung Pertiwi Anggita Esa Putri Fitrichia Aprilia, Trialisa Ari Sr Windyaswari Ari Sri Widyaswari Ari Sri Windyaswari Ari Sri Windyaswari Ari Sri Windyaswari, Ari Sri Ayu, Inna Puspa Bambang WIJIANTO Chandani Nurul Hafizah Citra Permata Sari dessy ratnasari Dewi, Renti Mutiara Dhimas Ariya Wibiksana Dinda Choirunnisa Dwi Ayu Pratiwi Dwi Nurahmanto Dwigantina, Ami Soega Dyah Nur Azizah, Dyah Nur Elfahmi Elfahmi Elfahmi Elfahmi Elfahmi Elfahmi, Elfahmi Ema Mutya Endang Kumolowati Esanda Zulfi Amedea Euis Reni Yuslianti Evi Umayah Ulfa Faizal Hermanto Farhan Fikri Alatas Fitriani, Adinda Fitrichia, Anggita Esa Putri Gazzali, Amirah Mohd Iis Inayati Rakhmat Ismail, Nursafira Khairunnisa Jaka Permana Jovie Mien Dumanauw Julia Ratnawati Julia Ratnawati Khairunisa Harizqi Nurul Husna Limbong, Remare Halomoan Lina Winarti Liza Pratiwi Melani, Putri Dwi Mufidah, Fania Mufti Muhamad Raihan Maulana Muhammad Irwan Mutya, Ema Niken Tunjung Murti Pratiwi Nira Purnamasari, Nira Nur Achsan Al-Hakim Nur Fauziyyah, Salma Alifia Nurhalizah, Dinda Siti Nurhayati, Viola Aditya Nursafira Khairunnisa Ismail Oktiyas Muzaky Luthfi Oktovia El Shara Paramita, Veronika Santi Pertiwi, Ananda Tunjung Pratiwi, Dwi Ayu Purnama, Uwan Purwoko, Agus Putri, Dhiffa Namira Alifia Ramelan, Riska Sigit Remare Halomoan Limbong Renti Mutiara Dewi Reyhan Adriana Deris Ridwan Ilyas Ridzka Magfirah Rifaz Muhammad Sukma Riska Sigit Ramelan Rizka Khoirunnisa Guntina Rizka Khoirunnisa Guntina RIZKA KHOIRUNNISA GUNTINA, RIZKA KHOIRUNNISA Safrudin, Nurul Safirah Septiani, Usi Sigid Pamungkas Wicaksono Silvy Julian Siti Muslichah Soraya Riyanti Soraya Riyanti Soraya Riyanti, Soraya Sufyan Zainul Arifin Sugiyanto Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sukrasno Sultan Salahudin Jamal Sundani Nurono Soewandhi SURYANI Susi Sunarty Sigalingging Suwidjiyo Pramono Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Totik Sri Mariani Tresa Tri Rayani Tresa Tri Rayani, Tresa Tri Trialisa Aprilia Tzazkia Febriyana Akbar Usi Septiani Viola Aditya Nurhayati Weni Widy Astuti Winda Nur Halimah Windyaswari , Ari Sri Wulandari, Yesi Yeni Karlina Yeni Karlina Yeni Karlina, Yeni Yenni Karlina Yesi Desmiaty, Yesi Yesi Wulandari Yuslianti, Euis Reni Zaini Alfahmi