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All Journal Jurnal Informasi Kesehatan Indonesia (JIKI) Ensiklopedia of Journal Best Journal (Biology Education, Sains and Technology) Jurnal Mandala Pengabdian Masyarakat Jurnal Penelitian Inovatif Indonesian Journal of Health Science INDOGENIUS Jurnal Ilmiah Kesehatan Masyarakat Sehat Rakyat: Jurnal Kesehatan Masyarakat Jurnal Pharmacopoeia Health Research Journal of Indonesia Bencoolen Journal of Pharmacy
Tri Danang Kurniawan
Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Formulasi dan Evaluasi Sediaan Emulgel Ekstrak Etanol 96% Daun Kemangi (Ocimum sanctum L. ) Berlianty Rahmahdini; Rose Intan Perma Sari; Evi Maryanti; Oky Hermansyah; Tri Danang Kurniawan
Health Research Journal of Indonesia Vol 4 No 5 (2026): Health Research Journal of Indonesia
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/hrji.v4i5.1347

Abstract

Daun kemangi (Ocimum sanctum L.) merupakan salah satu tanaman yang mengandung senyawa metabolit sekunder seperti flavonoid, fenolik, dan tanin yang berpotensi dimanfaatkan dalam sediaan farmasi topikal. Salah satu bentuk sediaan yang dapat dikembangkan adalah emulgel, yaitu kombinasi emulsi dan gel yang memiliki kemampuan penyebaran yang baik, mudah diaplikasikan, serta memberikan kenyamanan pada saat penggunaan. Penelitian ini bertujuan untuk memformulasikan ekstrak etanol 96% daun kemangi ke dalam sediaan emulgel serta mengevaluasi karakteristik fisik sediaan yang dihasilkan. Penelitian ini merupakan penelitian eksperimental laboratorium. Ekstrak daun kemangi diperoleh melalui metode maserasi menggunakan pelarut etanol 96%. Selanjutnya, ekstrak diformulasikan ke dalam empat formula, yaitu Formula 0 (tanpa ekstrak), Formula 1 (ekstrak 1%), Formula 2 (ekstrak 2%), dan Formula 3 (ekstrak 3%). Evaluasi karakteristik sediaan meliputi uji organoleptik, homogenitas, pH, viskositas, daya sebar, tipe emulsi, dan uji hedonik. Data hasil pengujian dianalisis secara deskriptif dan disajikan dalam bentuk nilai rata-rata dan simpangan baku. Hasil penelitian menunjukkan bahwa seluruh formula menghasilkan sediaan emulgel dengan bentuk semi padat dan homogen serta memiliki tipe emulsi minyak dalam air (M/A). Nilai pH yang diperoleh berada pada rentang 5,20–6,03 sehingga memenuhi persyaratan pH sediaan topikal, sedangkan nilai viskositas berkisar antara 6.583–9.280 cPs dan masih sesuai dengan standar yang ditetapkan. Hasil uji daya sebar menunjukkan bahwa seluruh formula memiliki kemampuan penyebaran yang baik, sementara hasil uji hedonik menunjukkan bahwa Formula 1 memperoleh tingkat penerimaan panelis tertinggi. Berdasarkan hasil evaluasi tersebut, ekstrak etanol 96% daun kemangi berhasil diformulasikan menjadi sediaan emulgel dengan karakteristik fisik yang memenuhi persyaratan mutu sediaan topikal. Kata kunci: Daun Kemangi, Emulgel, Ekstrak Etanol, Evaluasi Fisik, Formulasi.
Comparison study of vitamin c content in various brands of calamansi syrup from Bengkulu City using UV-Vis Spectrophotometry Mauliani Dwi Nathasyah; Putri Mulia; Samwilson Slamet; Tri Danang Kurniawan; Tika Hardini
Indonesian Journal of Health Science Vol 6 No 2 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i2.2120

Abstract

Calamansi oranges are a good source of vitamin C with high content of 27.43/100 g. Calamansi oranges are commonly processed into calamansi syrup. Calamansi syrup is one of flagship products of Bengkulu City, but information regarding the vitamin C content is not listed on the product packaging. This study aims to compare the vitamin C content of calamansi syrup from various brands in Bengkulu City using UV-Vis spectrophotometry. The study involves five samples of calamansi syrup from different brands. Qualitative analysis was conducted using 0.1% KMnO4, Iodine, and FeSO4 reagents, which showed that all five samples tested positive for containing vitamin C. The determination of the maximum wavelength was done at 265 nm with the regression equation y = 0.0659x + 0.0631 and R2 value of 0.9923. The vitamin C content obtained was 1.681% for Sample A, 5.880% for Sample B, 2.342% for Sample C, 1.979% for Sample D, and 2.478% for Sample E. The Kruskal-Wallis statistical analysis showed a significant difference among the samples (p < 0.05), indicating that the vitamin C content varies among the different brands. In conclusion, the five brands of calamansi syrup available in Bengkulu City contain vitamin C with varying levels.
Determination of total flavonoid content in 70% and 96% ethanol extracts of red seaweed (Eucheuma spinosum) obtaned by maceration using UV-Vis spect Rahma Arenda Syafika; Dwi Kurnia Putri; Suci Rahmawati; Encik Putri Ema Komala; Tri Danang Kurniawan
Indonesian Journal of Health Science Vol 6 No 2 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i2.2162

Abstract

Red seaweed (Eucheuma spinosum) is a marine biological resource containing bioactive compounds such as flavonoids with antioxidant potential. This study aimed to determine and compare the total flavonoid content in 70% and 96% ethanol extracts of Eucheuma spinosum obtained by maceration using a UV-Vis spectrophotometric method.This study employed an experimental laboratory design with a comparative approach. Samples were collected from the coastal area of Bengkulu, processed into simplicia, and extracted using 70% and 96% ethanol. Phytochemical screening was conducted to identify flavonoids, while quantitative analysis was performed using UV-Vis spectrophotometry with quercetin as a standard. Data were analyzed using normality, homogeneity, and independent sample t-test.The results showed that total flavonoid content in 70% ethanol extract was 9.2 ± 0.17 mg QE/g (0.92%), while in 96% ethanol extract it was 10.2 ± 0.12 mg QE/g (1.02%). The data were normally distributed and homogeneous (p > 0.05). The independent sample t-test indicated no significant difference between the two groups (p > 0.05).In conclusion, 96% ethanol tends to be more effective for flavonoid extraction, although the difference is not statistically significant.
Hubungan Pengetahuan dengan Sikap Masyarakat pada Penggunaan Antibiotik di Kelurahan Bumi Ayu Kota Bengkulu Defi Suryanti; Oky Hermansyah; Putri Mulia; Tri Danang Kurniawan; Dwi Dominica
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.7554

Abstract

Irrational use of antibiotics in the community remains a health problem that can increase the risk of antimicrobial resistance, Low levels of public knowledge are suspected to influence the formation of inappropriate attitudes toward antibiotic use. This study aimed to analyze the relationship between the level of knowledge and community attitudes toward antibiotic use in Bumi Ayu Village, Bengkulu City. This study used a quantitative method with an observational analytic design through a cross-sectional approach. The sample consisted of 110 respondents selected using a proportional cluster random sampling technique. Data were collected using questionnaires that had been tested for validity and reliability, with Cronbach’s Alpha values of 0.702 for the knowledge variable and 0.786 for the attitude variable. Data were analyzed using univariate and bivariate analyses with the Chi-Square test. The results showed that most respondents had low knowledge levels, with 50 respondents (45.5%), and poor attitudes, with 50 respondents (45.5%). The bivariate analysis showed a significant relationship between the level of knowledge and community attitudes toward antibiotic use, with a p-value of 0.000 (p < 0.05). Respondents with better knowledge tended to have better attitudes toward antibiotic use. Therefore, continuous health education through health workers and information media is needed to improve public understanding of rational antibiotic use in order to prevent antimicrobial resistance.
Co-Authors : Samwilson Slamet, : Samwilson Amelia Cantika Hendri Anggini dwi silfianti Anissa nayla septri Berlianty Rahmahdini Betta Nirwana Carissa Chindy Putri Wulandari Charly Agustin Defi Suryanti Deni Maryani Dominica, Dwi Dwi Dominica Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Dwi Kurnia Putri Encik Putri Ema Komala Evi Maryanti Fatima Khoirunisa Halimatus Sadiah Hikmawati Hikmawati Ibrahim Ayattulah Ikhsan Ikhsan Ikhsan Ikhsan Ikhsan Ikhsan Ledya Yulianti Maria Eka Patri Y Mauliani Dwi Nathasyah Mega Elfia Mesha Sevia Putri Miftahuljannah Miftahuljannah Muchammad Farid Muhammad Arifin Nabila Aulia Putri Nabila Rasyada Noor Annisa Susanto Oktoviani Oky Hermansyah Oky Hermansyah Oky Hermansyah Oon Sapta perma sari, rose intan Putri Mulia Putri Mulia Rahma Arenda Syafika Regina Anggun Pitri Reza Rahmawati Riani Apriwindi Risky Hadi Wibowo Rizqa Hasanah Rose Intan Perma Sari Rose Intan Perma Sari Rose Intan Perma Sari Rose Intan Perma Sari Rose Samwilson Slamet Samwilson Slamet Samwilson Slamet Savitri Cantika Sipriyadi Suci Rahmawati Suci Rahmawati Suci Rahmawati Suci Rahmawati Syahbananda Zulyan Palse Tiara Cantika Tiara Nisrina Fitri Tika Hardini Vernonia Yora Saki Vernonia Yora Saki Wirahmi, Nori Yendha Dwi Rolitta Yona Harianti Putri