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Aktivitas Antioksidan Ekstrak Metanol dan Fraksi N-Heksan-Etil Asetat Buah Paprika Merah (Capsicum annuum L.) Anisah, Nur; Warsi, Warsi; Ramandha, Muhammad Eka Putra; Isasih, Widani Darma; Inayati, Rizqa; Indriani, Nurul
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol. 1 No. 1 (2022): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v1i1.2459

Abstract

Buah paprika merah (Capsicum annuum L.) mengandung diantaranya adalah vitamin E, vitamin C, karotenoid, dan kapsaisinoid yang dapat digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada ekstrak metanol dan fraksi n-heksan-etil asetat buah paprika merah. Buah paprika merah segar diekstraksi dengan metode maserasi menggunakan pelarut metanol teknis kemudian difraksinasi secara bertingkat menggunakan pelarut n-heksan-dietil eter, hasil fraksi tidak larut n-heksan-dietil eter kemudian difraksinasi kembali menggunakan pelarut n-heksan-etil asetat. Fraksi n-heksan-etil asetat diuji secara kualitatif terhadap senyawa karotenoid yaitu β-karoten dengan uji KLT menggunakan fase diam silika gel F254 dan fase gerak metanol: aseton (1:1). Uji kuantitatif aktivitas antioksidan dilakukan dengan metode penangkapan radikal DPPH dengan parameter nilai IC50. Nilai IC50 selanjutnya dianalisis dengan menggunakan SPSS versi 20. Hasil uji kualitatif menunjukkan bahwa ekstrak metanol dan fraksi n-heksan-etil asetat mengandung senyawa β-karoten. Aktivitas antioksidan ekstrak metanol, fraksi n-heksan-etil asetat, dan standar β-karoten memiliki nilai IC50 berturut-turut sebesar 307,91, 281,69, dan 81,26 μg/mL. Berdasarkan hasil statistik, nilai IC50 fraksi n-heksan-etil asetat lebih kecil signifikan apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun lebih besar apabila dibandingkan dengan standar β-karoten. Fraksi n-heksan-etil asetat memiliki aktivitas antioksidan yang lebih poten apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun kurang poten apabila dibandingkan dengan standar β-karoten.
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol 13, No 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels are often considered waste despite being rich in bioactive compounds with potential as natural antioxidants. This study aimed to evaluate the antioxidant activity of an ethanol extract combination of Cavendis banana peel (Musa acuminata) and Kepok banana peel (Musa paradisiaca) using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The extraction process was conducted using 96% ethanol maceration, yielding an extraction efficiency of 9.13%. Phytochemical screening revealed the presence of flavonoids, tannins, saponins, and steroids/terpenoids in the extract. Antioxidant activity was assessed through the DPPH method, resulting in an IC50 value of 6.47 ppm and an AAI value of 5.40, classified as very strong antioxidants. These results are comparable to the positive control (Vitamin C), which had an IC50 value of 6.29 ppm and an AAI value of 5.56. The findings suggest that the ethanol extract combination of Cavendis and Kepok banana peels has significant potential as a natural antioxidant source applicable in the food, pharmaceutical, and cosmetic industries. Recommendations for future research include optimization of extraction methods, isolation of key active compounds, in vivo testing, and functional product formulation development to maximize the extract's potential.
Pelatihan Dasar-Dasar Microsoft Word Siswa SD Negeri 012 Samarinda Awang, Kevin Aditya Agusto; Indriani, Nurul; Azizah, Nur Shafa; syahria; Yodisya, Raihan; Jundillah, Muhammad Labib; Ibrahim, Muhammad Rivani
Pengabdian kepada Masyarakat Bidang Teknologi dan Sistem Informasi (PETISI) Vol. 3 No. 1 (2025): Pengabdian Kepada Masyarakat Bidang Teknologi dan Sistem Informasi
Publisher : Mulawarman University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/petisi.v3i1.2265

Abstract

Pelatihan dasar-dasar Microsoft Word di SDN 012 Samarinda dilaksanakan untuk meningkatkan keterampilan literasi digital siswa kelas VI. Pelatihan ini bertujuan membantu siswa memahami fungsi dan penggunaan fitur dasar Microsoft Word, seperti pembuatan dokumen, pengaturan format teks, dan penyimpanan file, guna mendukung kegiatan belajar mereka di era digital. Metode pelatihan dilakukan secara praktik langsung dengan pendekatan interaktif, di mana siswa diberikan panduan langkah demi langkah tanpa evaluasi formal. Hasil pelatihan menunjukkan peningkatan pemahaman siswa dalam menggunakan Microsoft Word, meskipun beberapa siswa menghadapi kesulitan dalam pengaturan layout dan penyisipan gambar. Antusiasme peserta cukup tinggi, dan mereka merasa pelatihan ini bermanfaat untuk mendukung pembelajaran. Kesimpulannya, pelatihan ini berhasil memberikan dampak positif terhadap keterampilan digital siswa dan diharapkan dapat dilakukan secara berkala untuk memastikan keberlanjutan pembelajaran teknologi informasi di tingkat sekolah dasar.
Antioxidant Activity of Ethanol Extract Combination of Cavendis Banana Peel (Musa acuminata) and Kepok Banana Peel (Musa paradisiaca) Using the DPPH Method Suhada, Adriyan; Ulya, Tuhfatul; Fardani, Roushandy Asri; Pertiwi, Ajeng Dian; Halid, Idham; Pauzan, Pauzan; Ratulangi, Wulan Ratia; Indriani, Nurul; Ariwidiani, Ni Nyoman; Widyan, Rosnalia; Utami, Evi Fatmi; Novianty, Wanda
Prisma Sains : Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Vol. 13 No. 3: July 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/j-ps.v13i3.15782

Abstract

Banana peels, often considered agricultural waste, are rich in bioactive compounds with significant antioxidant potential. This study evaluates the antioxidant activity of a combined ethanol extract from Cavendis (Musa acuminata) and Kepok (Musa paradisiaca) banana peels using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The extraction was performed via maceration with 96% ethanol, yielding 9.13%. Phytochemical analysis identified key compounds including flavonoids, tannins, saponins, and steroids/terpenoids, which are known to exhibit antioxidant properties. The extract demonstrated strong radical scavenging activity with an IC50 of 6.47 ppm and an Antioxidant Activity Index (AAI) of 5.40, comparable to Vitamin C (IC50 = 6.29 ppm; AAI = 5.56). These results indicate a synergistic effect from combining the two banana peel varieties, enhancing antioxidant efficacy beyond that reported for individual peels. This study supports the potential use of Cavendis and Kepok banana peel extracts as sustainable natural antioxidants for application in food preservation, nutraceuticals, and cosmetics. Future work should focus on optimizing extraction methods, detailed phytochemical profiling, stability assessment, and in vivo validation to advance product development and maximize health benefits.
Formulation and Evaluation Testing of Cream Nail Polish from Impatiens balsamina L. Seed Powder Sahra, Baiq Yatmi El; Indriani, Nurul; Sofya, Sri Winarni
Jurnal Multidisiplin Sahombu Vol. 5 No. 5 (2025): Jurnal Multidisiplin Sahombu, July - August (2025)
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cosmetics based on natural ingredients are increasingly favoured due to their perceived safety and environmental friendliness. One traditional plant with potential for development is water cress (Impatiens balsamina L.), which has long been utilised as a traditional medicine. This research aims to design a formulation and evaluate the preparation of cream nail polish with the additional component of water cress powder. This plant is known to contain flavonoids such as kaempferol and quercetin, which are beneficial for maintaining nail health. The study employed an experimental method with four formulations of nail polish, namely F0 (without powder), F1 (0.3%), F2 (0.5%), and F3 (0.75%). The preparation process involved the use of additional materials such as PVP, titanium dioxide, castor oil, methylparaben, and alcohol. Evaluation included organoleptic tests, homogeneity, pH, adhesion, spreadability, and hedonic testing involving 30 adolescent to adult panellists. The results indicated that all formulations exhibited good physical stability, pH values in accordance with standards, and high levels of preference, particularly for formulation F3 in terms of texture and final appearance. The addition of water cress seed powder provides additional benefits for nail moisture and protection. Thus, water cress seed powder can be considered as an alternative ingredient in the production of safer and more environmentally friendly cosmetic products. This research is expected to open new opportunities in the development of herbal-based cosmetics
Effectiveness Test of Ketapang Leaf Extract (Terminalia Catappa L.) as a Hepatoprotective Agent in Mice (Mus musculus) Induced by Acetaminophen Anjani, Desak Sri Ayu; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Jurnal Multidisiplin Sahombu Vol. 5 No. 5 (2025): Jurnal Multidisiplin Sahombu, July - August (2025)
Publisher : Sean Institute

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Abstract

Drug-induced liver injury (DILI) is a leading cause of acute liver failure, with acetaminophen being the most frequent etiological agent. Overdose induces formation of the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI), resulting in glutathione depletion, oxidative stress, and hepatocellular necrosis. This study aimed to evaluate the hepatoprotective effect of ethanolic extract of Terminalia catappa L. leaves in male mice (Mus musculus) with acetaminophen-induced acute liver injury. A post-test only control group design was employed using 20 mice divided into five groups: negative control (Na-CMC), positive control (N-acetylcysteine), and three treatment groups receiving T. catappa extract at doses of 200, 400, and 600 mg/kg BW. Acetaminophen was administered intraperitoneally at 500 mg/kg BW. Serum SGPT and SGOT levels were quantified spectrophotometrically, and phytochemical screening confirmed the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids. Extract administration significantly (p < 0.05) reduced SGPT and SGOT levels compared to the negative control, with a clear dose-dependent trend; the 600 mg/kg BW group achieved biochemical parameters approaching those of the N-acetylcysteine group. The hepatoprotective effect is likely mediated by flavonoid-driven antioxidant and anti-inflammatory mechanisms. These findings indicate that T. catappa extract is a promising, safe, and cost-effective plant-based hepatoprotective agent, meriting further investigation toward clinical application as an adjunct therapy for drug-induced hepatotoxicity
PENGEMBANGAN PRODUK MINYAK KEMIRI MELALUI PEMBERDAYAAN MASYARAKAT DAN PEMASARAN KREATIF DI DESA SELENGEN KECAMATAN KAYANGAN KABUPATEN LOMBOK UTARA Hafiz, Lalu Muhamad Fajri; Azkia, Tina Imro’atun; Indriani, Nurul; Irham, Muhamad; Aprilia, Dwi Ayu; Aini, Zahratul; Yodita, Zahrawana Putri; Utami, Nadia Fitri; Aini, Niza Husnul; Apriani , Nurul Aulia; Suartika, I Made
Jurnal Wicara Vol 1 No 6 (2023): Jurnal Wicara Desa
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/wicara.v1i6.3490

Abstract

Kemiri (Aleurites Moluccana) is a plantation commodity that has the potential to be well developed. This is strongly influenced by the candlenut market which is increasingly open due to the increasing demand for candlenut consumption, both domestically and abroad. The candlenut plant has many benefits, such as being used by people to grow hair, heal skin wounds, diarrhea, asthma and increase analgesic effects. However, the part of the plant that has high economic value is the candlenut seed. The method of implementing activities used to improve the quality of community products in hazelnut oil production uses three methods, namely processing, manufacture or design of packaging and packaging, and marketing. The results of the implementation of community empowerment practical work courses that have been carried out by KKN students in Selengan village try to participate in helping develop candlenut oil products to improve the quality of community products as a source of income in Selengen village.
Pemanfaatan Eklstrak Limbah Kulit Buah Rambutan (Nephelium Lapaceum L). dalam Formulasli Body Lotion Paturrahmi, Wilda Marta; Indrianii, Nurul; Ramandha, Muhammad Eka Putra
Jurnal Penelitian Perawat Profesional Vol 6 No 5 (2024): Oktober 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i5.4469

Abstract

Penelitian ini bertujuan untuk mengetahui efek antioksidan ekstrak kulit buah rambutan (Nephelium lappaceum L.) dalam melembabkan kulit dan menentukan formulasi body lotion yang paling efektif. Kulit buah rambutan mengandung senyawa antioksidan yang berpotensi memberikan manfaat bagi kesehatan kulit.Penelitian eksperimental ini menguji aktivitas antioksidan ekstrak kulit buah rambutan dengan variasi konsentrasi menggunakan metode DPPH. Aktivitas antioksidan diukur dengan spektrofotometer UV-Vis. Ekstrak kemudian diformulasikan ke dalam beberapa variasi body lotion yang dievaluasi profilnya meliputi organoleptis, homogenitas, pH, daya sebar, daya lekat, viskositas, dan iritasi. Hasil penelitian menunjukkan bahwa ekstrak kulit buah rambutan memiliki aktivitas antioksidan yang berpotensi melembabkan kulit. Beberapa formulasi body lotion dengan penambahan ekstrak memenuhi kriteria sediaan yang baik. Ekstrak kulit buah rambutan berpotensi sebagai bahan aktif dalam formulasi body lotion dengan efek melembabkan. Penelitian lebih lanjut diperlukan untuk mengoptimalkan formulasi dan menguji efektivitasnya pada manusia.
Phytochemical Screening, Total Flavonoids and Antioxidants of Kalanchoe Pinnata Linn. Leaves Qomaliyah, Eka Nurul; Indriani, Nurul; Rohma, Atika; Islamiyati, Ricka
Current Biochemistry Vol. 10 No. 1 (2023)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.10.1.1

Abstract

Kalanchoe pinnata Linn. or in Indonesia known as cocor bebek, this plants grow well in temperate and tropical regions. Cocor bebek is used to treat several diseases including skin diseases, wound healing, kidney stones, gallstones, diabetes. The pharmacological activities of cocor bebek leaves have been reported as anti-inflammatory, anti-oxidant and anti-microbial. The objective of this study is to determine the metabolite content of cocor bebek leaves, total flavonoid levels and antioxidant activity. Observations of secondary metabolites of cocor bebek leaves were carried out through qualitative secondary metabolite screening, while total flavonoid levels were carried out quantitatively UV-VIS with quercetin as a comparison, atioksidan activity through DPPH molecular inhibition testing. The results of this study indicate that cocor bebek leaves contain alkaloids, flavonoids, saponins, triterpenoids, tannins and phenols. 200gr of cocor bebek leaves obtained % yield extract is 14.63%. The total favonoid content obtained was 8.77% of quercetin, while the antioxidant inhibition of DPPH molecules obtained IC50 of 97.42 ppm.
KMHD UBG Mengabdi: Pemanfaatan Tanaman Obat Keluarga sebagai Health Maintenance pada Masyarakat Penyakit Kronis Aji Kresnapati, Nyoman Bagus; Indriani, Nurul; Satria Wirananda, I Nengah
Jurnal Ilmiah Pengabdian dan Inovasi Vol. 2 No. 4 (2024): Jurnal Ilmiah Pengabdian dan Inovasi (Juni)
Publisher : Insan Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57248/jilpi.v2i4.419

Abstract

The aim of this activity is to educate residents about the use of Tanaman Obat Keluarga (TOGA) and honey as self-medication in Batu Kumbung Village, Narmada District, West Lombok, NTB. The method of this activity is Komunikasi, Informasi dan Edukasi (KIE) based on Participatory Action Research (PAR), which is a socialization approach using active community participation which aims to explore problems such as health checks for BMI, blood pressure and glucose and from these results, a solution is implemented, namely KEI TOGA and honey to the community. The results of the activity showed that the average age of the community was 36 years, BMI 21.08% (normal 17-25%), blood pressure 119/75 mmHg (normal <130 mmHg), glucose level 95 mg/dL (normal <150 mg/dL), it was concluded that the average health status of the community was in the normal category. The implication of this activity is the community's active role so that this activity is successful and the community receives TOGA education as a self-medication treatment.