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Uji Aktivitas Antibakteri Ekstrak Daun Karamuntin (Rhodomyrtus tomentosa (Aiton) Hassk.) terhadap Bakteri Streptococcus mutans Ramadhanty, Dewi Alfisyah; Lestari, Yulianita Pratiwi Indah; Nashihah, Siti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (858.701 KB) | DOI: 10.35617/jfionline.v15i1.112

Abstract

Abstract: Indonesia has many medicinal plants that can used to treat various diseases. One of the plants is the leaves of karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.). Traditionally, karamunting leaves are used as a treatment in dental caries, wound care, and scabies. This study was aimed to determine the antibacterial effect of karamunting leaves ethanol extract against Streptococcus mutans by the well method. The design of this study was experimental laboratory research. The sample was karamunting leaves ethanol extract. The extracts were evaluated for antibacterial activity against Streptococcus mutans using the well method with a concentration of 6,25%; 12,5%; 25%; and 50% w/v. The result showed karamunting leaves ethanol extract provided an antibacterial activity against Streptococcus mutans with an inhibition zone diameters of 17,7±0,0577; 22,6±0,2516; 25,3±0,1527; and 28,3±0,0577 mm. at the concentration of 6,25% w/v, 12,5% w/v, 25% w/v, and 50% w/v, respectively. karamunting leaves ethanol extract had significant antibacterial activity against Streptococcus mutans at the concentration 50% w/v with inhibition zone diameters of 28,3 mm.
EDUKASI TENTANG DIABETES MELLITUS, UPAYA PENCEGAHAN SAMPAI PENGOBATANNYA, MENUJU DESA KARANG BUNGA SEHAT Mulyani, Tuty; Mi’rajunnisa, Mi’rajunnisa; Yulianita Pratiwi Indah Lestari; Rizka Mulya Miranti; Nurul Fajeriyati
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 2: Juli 2025
Publisher : Bajang Institute

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Abstract

Diabetes Melitus merupakan suatu penyakit akibat penumpukan glukosa dalam darah dan terjadi akibat tubuh tidak memproduksi cukup insulin, atau tidak bisa mempergunakan insulin secara tepat yang ditandai dengan kondisi hiperglikemia dengan gejala khas yaitu buang air kecil terus menerus (dalam jumlah banyak) dengan rasa manis (kencing manis). Diabetes melitus memerlukan penanganan medis, edukasi tentang self management serta dukungan yang berkelanjutan untuk mencegah penyakit komplikasi akut maupun kronis. Tujuan kegiatan ini adalah untuk meningkatkan pemahaman masyarakat terkait Diabetes Mellitus, cara pencegahan serta pengobatannya. Kegiatan ini dilakukan melalui penyuluhan interaktif, pre-test dan post-test, diskusi tanya jawab dan demonstrasi untuk cara penggunaan insulin dengan benar. Peserta pada penyuluhan ini adalah 20 orang ibu-ibu PKK Desa Katang Bunga, Kecamatan Mandastana, Kabupaten Barito Kuala. Kegiatan ini berjalan lancer dan baik. Peserta sangat antusias dan bersemangat dalam mengikuti kegiatan ini. Berdasarkan hasil pre-test dan post-test menunjukkan bahwa terjadi peningkatan pemahaman peserta terkait Diabetes Mellitus, cara pencegahan penyakit hingga penggunaan obat yang tepat.
Warna-warni berbahaya: edukasi bahaya pewarna kimia pada jajanan anak sekolah di desa Karang Bunga Lestari, Yulianita Pratiwi Indah; Miranti, Rizka Mulya; Riyadi, Ahmad Irfan; Raqiqah, Annisa; Hidayatullah, Aulia Fitriani; Silvana, Helen; Syawalia, Khaliza; Zannah, Miftahul
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 6 No. 2 (2025): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v6i2.600

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Children are highly exposed to various snacks sold freely around schools, many of which may contain hazardous synthetic food dyes. These dyes can pose health risks, especially when consumed continuously without supervision. This community service aimed to increase students' awareness at SDN Karang Bunga about the dangers of synthetic food coloring in school snacks. The activity was conducted through counseling and education sessions on June 27, 2024. Methods included presentations, discussions, games, pretests and posttests, and questionnaire-based evaluations. The results showed increased knowledge based on the pretest and posttest scores and high satisfaction from teachers and students. This program is expected to build critical awareness among school-aged children in choosing safe food.
FORMULASI DAN EVALUASI SIFAT FISIK LIP GLOSS TINTA CUMI (LOLIGO SP) Putri, Audy Apriliana; Fayza Nindya Nur’Assyfa; Muhammad Ridha; Nurul Hasni Julianti; Shada Adila Abadi; Yulianita Pratiwi Indah Lestari
Journal of Innovation Research and Knowledge Vol. 4 No. 3: Agustus 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v4i3.8277

Abstract

Tinta cumi memiliki berbagai manfaat dalam pemanfaatannya dalam aktivitas biologis salah satunya sebagai antioksidan, sehingga baik untuk menangkal radikal bebas, melembabkan dan menutrisi kulit bibir. Lip gloss adalah salah satu produk kosmetik yang dimana memiliki berfungsi untuk melembabkan dan memberikan efek kilau yang agak mengkilap di bibir, atau digunakan untuk memberikan efek warna tertentu. Sediaan lip gloss memiliki kaandungan minyak yang tinggi sehingga memberikan kesan melembabkan, berkilau atau glossy dengan bentuk cair dan padatan lunak. Tujuan dari penelitian ini adalah untuk mengetahui sifat fisik dari sediaan lip gloss tinta cumi yang dibuat dengan berbagai konsentrasi formula dengan kontrol negatif dan kontrol positif. Kontrol negatif F0, konsentrasi 0,5% F1, konsentrasi 1% F2, konsentrasi 1,5% F3, dan kontrol negatif F4. Pembuatan ekstak tinta cumi menggunakan metode refluks kemudian dilanjutkan dengan formulasi sediaan dan uji sifat fisik sediaan meliputi uji organoleptis, uji homogenitas, uji ph, uji daya sebar, dan uji viskosistas. Hasil dari semua uji didapat yaitu formulasi 2 dengan konsentrasi 1% ekstrak serbuk tinta cumi yang memiliki sifat fisik terbaik dengan beberapa uji yang dilakukan
REVIEW JURNAL PENGELOLAAN LIMBAH PADAT, CAIR, DAN GAS DALAM INDUSTRI FARMASI REVIEW OF JOURNAL OF SOLID, LIQUID, AND GAS WASTE MANAGEMENT IN PHARMACEUTICAL INDUSTRY Yuspa, Nor Latifah; Yulianita Pratiwi Indah Lestari
Jurnal Cakrawala Ilmiah Vol. 3 No. 12: Agustus 2024
Publisher : Bajang Institute

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Abstract

Pharmaceutical industry waste management is a critical aspect in maintaining environmental and public health. Waste from the pharmaceutical industry includes potentially hazardous solid, liquid, and gaseous wastes. Various management methods have been developed, such as inertization, safe stockpiling, incineration, encapsulation, and deep burial for solid waste; chemical disinfection, sewer disposal, and treatment in wastewater treatment plants for liquid waste; and waste gas treatment technologies for gaseous waste. In Indonesia, PT Indofarma Tbk in Bekasi has implemented various stages of waste management, including reduction, reuse, containerization and collection, internal transportation, internal treatment, temporary storage, external transportation, and outplant treatment. This study used a qualitative methodology with a literature review from the Scopus and SINTA databases, and the results were presented in a descriptive narrative. In conclusion, effective pharmaceutical waste management is essential to minimize negative impacts on the environment and public health.
REVIEW PENGENDALIAN LIMBAH PADAT SERTA BAHAN BERBAHAYA (B3) DI RUMAH SAKIT Muhammad, Muhammad; Annisa Zahra; Suciati Nurrani; Halimi, Halimi; Nor Latifah; Yulianita Pratiwi Indah Lestari
Jurnal Cakrawala Ilmiah Vol. 3 No. 12: Agustus 2024
Publisher : Bajang Institute

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Abstract

Health waste is waste generated from health activities it hospitals. Hospital operations generate a variety of waste byproducts, solid waste that contain hazardous and poisonous bacteria. Operational activities and B3-containing service facilities generate hazardous and toxic waste. The purpose of this study is to learn more about and gain an understanding of how hospitals handle hazardous and toxic chemicals (B3) and solid waste. The purpose of this study is to learn more about and understand how hospitals handle hazardous and toxic materials (B3) as well as solid waste. A review of the literature sourced from reputable pharmaceutical publications, PubMed, Google Scholar, and other literature search results is the methodology employed. The analysis chosen articles was of the hospital's solid and (B3) waste management system. From the literature search, 7 journals out of 1,910 articles were found that matched the criteria with the search string 2015 to 2024. The study's findings demonstrated the necessity of trash sorting for the efficient management of hazardous chemicals (B3) and solid waste in hospitals. collection and destruction. Techniques such as incineration of medical waste and proper segregation of non-medical waste are important to prevent negative impacts on health and the environment.
The analysis of hydroquinone levels in the product of whitening hand and body lotion in online shops, using the UV-Vis spectrophotometry method Mellynia, Sri Agfa; Lestari, Yulianita Pratiwi Indah; Mi'rajunnisa
Jurnal Ilmiah Farmasi Vol. 21 No. 2 (2025): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol21.iss2.art6

Abstract

Background: Hydroquinone serves as a skin-lightening agent by suppressing melanin production. However, its usage in cosmetic formulations has been prohibited under the Indonesian Food and Drug Authority regulations, as stated in Regulation Number 18 of 2015. Despite this restriction, numerous studies show that various whitening hand and body lotion products commonly contain hydroquinone.Objective: This study aimed to conduct a qualitative and quantitative analysis of hydroquinone in body-whitening hand and body lotion products available through online retail platforms.Method: The methodology employed in this study involved the use of Thin Layer Chromatography (TLC) for qualitative analysis, complemented by UV-Vis spectrophotometry, which had undergone prior validation to serve as a quantitative analytical tool.Results: The qualitative analysis conducted via Thin Layer Chromatography (TLC) identified six positive samples containing hydroquinone, characterized by an Rf value of 0.75. According to the validation results, the method demonstrated a linearity value with a correlation coefficient (r) of 0.9976, a limit of detection (LOD) of 0.3862 g/mL, and a limit of quantification (LOQ) of 1.2872 g/mL. An RSD value of 1.912% showed precision, while accuracy was confirmed through a recovery rate of 96.77%. The validation outcomes suggested that this approach is robust for analyzing hydroquinone in body-whitening hand and body lotion products. The UV-Vis spectrophotometry result showed that samples 1 through 6 had hydroquinone in them at levels of 0.0418, 0.0448, 0.0361, 0.0283, 0.0365, and 0.3193%, respectively.Conclusion: The research conducted revealed that the qualitative analysis using Thin-Layer Chromatography (TLC) yielded six positive samples, indicating the presence of hydroquinone. Furthermore, the quantitative analysis indicated that whitening hand and body lotion products available in online shops contained hydroquinone at concentrations ranging from 0.0283 to 0.3193 g/mL. This finding underscores the continued prevalence of prohibited chemicals in certain cosmetic products.
PEMANFAATAN TERATAI PUTIH SEBAGAI BAHAN BAKU PEMBUATAN SELULOSA MIKROKRISTALIN MENGGUNAKAN HIDROLISIS ENZIMATIK DARI RAYAP Coptotermes sp. Yulianita Pratiwi Indah Lestari; Mi'rajunnisa; Raudatul Patimah; Rizka Mulya Miranti; Tuty Mulyani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.742

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Microcrystalline cellulose is still imported by the Pharmaceutical Industry in Indonesia even though Indonesia has large natural resources but they have not been utilized optimally. Microcrystalline cellulose can be obtained from residue (extraction dregs) in the lotus plant extraction process, namely in the form of simplicia powder which will not be used again (organic solid waste). This research aims to obtain microcrystalline cellulose from several parts of the white lotus plant (Nymphaea nouchali Burm. F.) using the enzymatic hydrolysis method using cellulase from the termite Coptotermes sp., then the quality of the powder will be tested and compared with Avicel PH 101. Each part The white lotus is extracted, then the residue is delignified to obtain α-cellulose, then hydrolyzed with crude extract from Coptotermes sp termite cellulase. so that microcrystalline cellulose is obtained which will then be characterized and compared with the commercial version, namely Avicel® PH 101. The highest yield of microcrystalline cellulose is found in leaves with a yield of 95.3%, followed by leaf stalks 89.3%, flower stalks 75.7%, and the yield lowest in interest with a percentage of 74%. The physical characteristics in the form of color reaction, organoleptics, solubility and pH of white lotus microcrystalline cellulose powder show similarities with the comparison standard. It can be concluded that microcrystalline cellulose powder from several parts of the white lotus plant can be an alternative in obtaining cellulose raw materials from natural sources.
EDUKASI BEYOND USE DATE (BUD) DALAM MENDUKUNG KEAMANAN PENGGUNAAN OBAT PADA KESEHATAN KELUARGA DI DESA SEMANGAT BAKTI Ahdyani, Risa; Mi’rajunnisa, Mi’rajunnisa; Lestari, Yulianita Pratiwi Indah; Wahyudi, Muhammad Rezky; Maulidia, Fiona; Yuvela, Gabri; Sa’diah, Rini; Apriliana, Rusnia; Rahmadani, Syifa Askila
Journal of Community Empowerment Vol 5, No 1 (2026): Maret
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jce.v5i1.38601

Abstract

ABSTRAK                                                                                     Keterbatasan akses terhadap fasilitas dan tenaga kefarmasian di Desa Semangat Bakti, Kabupaten Barito Kuala, Provinsi Kalimantan Selatan, berpotensi menyebabkan penggunaan obat yang tidak aman di tingkat rumah tangga. Salah satu permasalahan utama adalah rendahnya pemahaman masyarakat mengenai Beyond Use Date (BUD), yaitu batas waktu aman penggunaan obat setelah kemasan dibuka atau obat diracik. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan kesadaran masyarakat mengenai penggunaan obat yang aman dan rasional melalui edukasi BUD. Penyuluhan melibatkan mitra Ibu Pemberdayaan Kesejahteraan Keluarga (PKK) Desa Semangat Bakti sejumlah 29 orang. Kegiatan diawali dengan koordinasi dan pemenuhan aspek legalitas di tingkat Desa. Penyuluhan dilaksanakan pada tanggal 27 Juni 2025 menggunakan metode ceramah dan diskusi interaktif yang didukung media Microsoft PowerPoint dan leaflet serta contoh produk. Evaluasi dilakukan melalui pretest dan posttest menggunakan kuesioner berisi 10 pernyataan yang dianalisis dengan uji paired sample t-test untuk membandingkan pengetahuan peserta sebelum dan sesudah kegiatan penyuluhan. Hasil analisis menunjukkan terdapat peningkatan pengetahuan peserta yang signifikan setelah penyuluhan (p < 0,05). Kesimpulannya, kegiatan edukasi mengenai BUD efektif dalam meningkatkan pemahaman masyarakat terkait batas waktu aman penggunaan obat dan berpotensi mendorong penerapan penggunaan obat yang lebih aman dan rasional dalam kehidupan sehari-hari.Kata kunci: Edukasi; Ibu PKK; Beyond Use Date. ABSTRACTLimited access to pharmaceutical facilities and qualified pharmaceutical personnel in Semangat Bakti Village, Barito Kuala Regency, South Kalimantan Province, may contribute to unsafe medication practices at the household level. One of the primary challenges identified is the limited community understanding of Beyond Use Date (BUD), defined as the maximum safe period for medication use after the primary packaging has been opened or the product has been compounded. This community service program aimed to improve public knowledge and awareness regarding safe and rational drug use through BUD education. The activity involved 29 members of the Family Welfare Empowerment (PKK) group in Semangat Bakti Village as participants. The program was initiated with coordination and the fulfillment of legal requirements at the village level. The educational intervention was conducted on June 27, 2025, employing lecture-based and interactive discussion methods, supported by Microsoft PowerPoint presentations, leaflets, and sample products. Evaluation was performed using pretest and posttest assessments with a questionnaire consisting of 10 statements. The data were analyzed using a paired sample t-test to compare participants’ knowledge before and after the intervention. The results demonstrated a statistically significant improvement in participants’ knowledge following educational intervention (p < 0.05). In conclusion, BUD-focused education was effective in improving community understanding of safe medication use limits and may contribute to the adoption of safer and more rational medication practices in daily life.Keywords: Education; Family Welfare Empowerment; Beyond Use Date.
Co-Authors Afzan Ridhani Agustina Tri Wahyuni Ahdyani, Risa Annisa Zahra Apriliana, Rusnia Aris Purwanto Asyfa Putri Ramadhani Chasanah, Uswatun Cindy Cenora Dhea Indah Cahyani Dina Azizah Dita Putri Aulia Fandiny, Yeny fatimah Fatimah Fayza Nindya Nur’Assyfa Halimi, Halimi Hasbi As-Shiddiq Hayati, Mardia Hendera Hendera Herman Suryadi Hidayatullah, Aulia Fitriani Hikmah Fitriani Hilmalia Huzaeroh, Anifatu Irfan Zamzani Kamalia, Noor Kusumo, Djati Wulan Maharani, Dewi Malinda Apriliani Maulidia, Fiona Maulidwina Bethasari Maulinda Nur Pramudyas Primia Setyaningrum Mellynia, Sri Agfa Mi'rajunnisa Mi'rajunnisa Mi'rajunnisa Mi'rajunnisa Mi’rajunnisa Mi’rajunnisa Mi’rajunnisa, Mi’rajunnisa Muhammad Muhammad Muhammad Muhammad Muhammad Muhammad Ridha Muhammad Samawi Mulyani, Tuty Munawwarah, Siti Mustharah, Mustika Mustika Muthaharah Nashihah, Siti Nor Azizah Rahmah Sari Nor Latifah Nor Syifa Nurul Fajeriyati Nurul Hasni Julianti Putri Amelia Putri, Audy Apriliana Rahmadani, Syifa Askila Rahmalisa Hafifah Rahmalisa Hafifah Rahmat Fajar Nafarin Rahmawati Rahmawati Raissya Putratama Ramadhanty, Dewi Alfisyah Raqiqah, Annisa Raudatul Patimah Raudatul Patimah Raudatul Patimah, Raudatul Riyadi, Ahmad Irfan Rizka Amalia Rizka Mulya Miranti Rizki Ramadani Rusdah Safitri, Salsabila Nurlaila Salsabilla, Syifa Aulia Saputra, Muhammad Aditya Belly Sari, Cindy Fransiska Sazidan, Akhbar Arya Jouraist Sa’diah, Rini Shada Adila Abadi Silvana, Helen Siti Mursyidah Siti Mursyidah Siti Nur Habibah Soraya Aldeina Soraya Aldeina Suciati Nurrani Sutriyo Syarbani, Syarbani Syawalia, Khaliza Triadisti, Nita Tuty Tuty Mulyani Wahyudi, Muhammad Rezky Yuspa Yuspa Yuspa Yuspa, Nor Latifah Yuspa, Yuspa Yuvela, Gabri Zahra, Raudhatuz Zannah, Miftahul