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All Journal Alchemy : Journal of Chemistry CHEMPUBLISH JOURNAL Pharmascience Jurnal Geografi Chemistry Indonesian Journal of Chemical Research Indonesian Journal of Chemical Analysis (IJCA) Molekul: Jurnal Ilmiah Kimia Journal of Appropriate Technology for Community Services Jurnal ABDINUS : Jurnal Pengabdian Nusantara Bubungan Tinggi: Jurnal Pengabdian Masyarakat Community Empowerment Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Experimental and Clinical Pharmacy (JECP) Welfare: Jurnal Pengabdian Masyarakat Bohr: Jurnal Cendekia Kimia NAWASENA: Journal of Community Service Helium: Journal of Science and Applied Chemistry
Rizki Rachmad Saputra
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Universitas Palangka Raya, Palangka Raya, 73112, Indonesia
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : CHEMPUBLISH JOURNAL

 1 
Claisen Rearrangement Toward Cyclic Compound on Different Organic Synthesis Methods: Short Review Saputra, Rizki Rachmad; Rosalina, Reny; Pramudita, Dimas; Wulandari, Oktavia Rahmi; Yuneta, Yuneta; Gracia, Amanda Natania; Sugiyani, Tina; Imelya, Marsya
Chempublish Journal Vol. 7 No. 2 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i2.26053

Abstract

The synthesis of functional and complex organic compounds is majorly performed by the Claisen rearrangement method. Claisen rearrangement is one of [3,3] sigmatropic rearrangements, a complex method in the synthesis of organic compounds, where it is mostly used to construct stereoselective compounds. It can be combined with other synthesis methods to synthesize organic compounds giving satisfactory results based on the method used, temperature, time, and yield produced. This review aimed to summarize several recent advances in synthesizing organic compounds through Claisen rearrangement reactions. An understanding of the mechanism and applications of this reaction might improve the ability to synthesize innovative and useful organic compounds in various fields of life sciences.
Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach Priyadi, Muhammad; Saputra, Rizki Rachmad
Chempublish Journal Vol. 7 No. 1 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i1.26098

Abstract

Dental caries is one of the problems in dental disorders suffered by many people. There have been many ways of handling such as using temu kunci and lemongrass plants. This study aims to determine the antibacterial activity of caries in vitro and predict the mechanism of action of the bacteria that cause caries Streptococcus mutans.  Temu kunci and lemongrass were extracted using ethyl acetate solvent. antibacterial tests against Streptococcus mutans were carried out using diffusion tests with a combination treatment of temu kunci: serai extracts 5% b/v: 5% b/v, 5% b/v: 10% b/v, and 10% b/v: 5% b/v. The positive control used amoxicillin and DMSO as a negative control. Potency as an anticaries drug of drived compound from Temu Kunci and Serai were evaluated by molecular docking using glucosyltransferase (3AIC). The results showed that the combination of temu kunci and serai with concentration 10% b/v: 5% b/v has potential as anticaries against Streptococcus mutans. Molecular studies depicted that Panduratin A, Isopanduratin, and 1,3-O-di-p-coumaroylglycerol have great activity toward 3AIC, respectively. Especially for Panduratin A and Isopanduratin, those compound depicted great and similar binding affinity (-8.4 kcal mol-1) that lower than Acarbose as native ligand  (-8.3 kcal mol-1). Furthermore, those compound binding similarity ilustrated activity mechanism similarly with native ligand toward receptor. Additionally, the profiling drug-target interaction suggested Temu Kunci’s derived compounds have great potential as anticaries treatment.   
Exploring the Viability of Waste Durian (Durio zibethinus) Seeds and Cempedak (Artocarpus integer) Seeds as Nutritive Resources: An Analytical Study of Their Suitability via Alcohol and Glucose Assays Syarpin, Syarpin; Saputra, Rizki Rachmad; Haliza , Nur; Anista, Anista; Yanti, Helda; Sisilya, Tahsya Amanda; Fahmi, Rifaldi Lutfi
Chempublish Journal Vol. 7 No. 2 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i2.27983

Abstract

Durian (Durio zibethinus) and Cempedak (Artocarpus integer), prominent staples in Indonesia, harbor seeds that can be harnessed for the production of 'Tapai', a traditional fermented product. This fermentation process within cempedak and durian seeds manifests in the generation of alcohol and glucose at discernible thresholds. Motivated by the prevalent underutilization of durian and cempedak seeds leading to wastage, this study aims to assess the viabilities of Tapai derived from these seeds by scrutinizing their alcohol and glucose profiles. Employing a quantitative descriptive approach, the research centers on cempedak and durian seed Tapais as the primary samples. Focusing on variables like alcohol and glucose content, the investigative technique incorporates distillation and titration using the Luff Schoorl method. Results are subsequently organized in frequency distribution tables following coding and tabulation. Observations reveal that alcohol and glucose levels in cempedak seed Tapai on the 10th day stand at 0.00% and 30.05%, respectively, while on the 15th day, they escalate to 4.88% and 41.92%. In the case of durian seed Tapai, levels on the 10th day are recorded at 4.88% for alcohol and 36.90% for glucose. On the 15th day, these figures rise to 16.57% for alcohol and 46.53% for glucose. Ultimately, this study underscores that the alcohol and glucose concentrations in cempedak and durian seed Tapais experience progressive augmentation over a 5-day period, rendering them safely consumable in moderate quantities.
Co-Authors Abdul Mannan Abed Nego Purba Abidin, Muh Rais Alfanaar, Rokiy Alonge, Titus Adeyemi Anggun Tanduwinata Anista, Anista Ansori Rahman Ariska, Risya Aulanni'am Aulanni'am Ayu Puspita Sari Bela D Chian-Yi Liu Citrariana, Shesanthi Decenly Decenly Decenly, Decenly Dicky Perwira Ompusunggu Dominikus Diki Wahyudi Dongoran, Junita Dwijayanti, Rts. Sherly eka novitasari Erwin Prasetya Toepak Esintia Kristia Fahmi, Rifaldi Lutfi Fairozi, Raiyan Fauziah, Anisa Rahma Gracia, Amanda Natania Gunawan, Yohanes E Gunawan, Yohanes Edy Haliza , Nur Harianja, Henrigen Helmi Auliyah Istiqomah Imelya, Marsya Isaura, Anastasya Jamilah Jamilah Jeddah Yanti Junita Dongoran Kalalinggi, Septaria Yolan Liu, Chian-Yi Maknun, Luluil Mannan, Abdul Marvin Horale Pasaribu Mokhamat Ariefin Muh Rais Abidin Muhammad Priyadi Nababan, Jesika Nainggolan, Yuni Damayanti Ni Luh Kemmy Caesaria Ni Wayan Prema Mulya Sari Oksal, Efriyana Okta Prianus Ozi Adi Saputra, Ozi Adi Paksi, Pandu Gizta Rapi Pramudita, Dimas Prianus, Okta Purba, Abed Nego Qaiyimah, Dinil Reny Rosalina, Reny Retno Agnestisia Rian Ka Praja Riandy Putra Sari, Meiyanti Ratna Kumala Simangunsong, Sri Yulandari Simbolon, Wenika Sisilya, Tahsya Amanda Siska, Amelia Siti Misbah Aisah Siti Unvaresi Misonia Beladona Sugiyani, Tina Sulistiawati, Putri Suma, Joy Angel Aria syarpin, syarpin Tampubolon, Mulani Jeni Lestari Thathit Suprayogi Titus Adeyemi Alonge Togatorop, Hana Esrani Togi Tampubolon Togi Tampubolon Wulandari, Oktavia Rahmi Yahya Febrianto Yanti, Helda Yuliana Yuliana Yuliana Yuneta, Yuneta