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All Journal BAREKENG: Jurnal Ilmu Matematika dan Terapan ULIN: Jurnal Hutan Tropis Jurnal Riset Teknologi Industri Jurnal Abdi: Media Pengabdian Kepada Masyarakat Bubungan Tinggi: Jurnal Pengabdian Masyarakat Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Multidisciplinary Applied Natural Science Jurnal Hasil Pengabdian Masyarakat (JURIBMAS) Journal of Bio-molecule Research And Engineering Andan Jejama: Indonesian Journal Of Community Engagement
Rico Ramadhan, Rico
Departement Of Chemistry, Faculty Of Science And Technology, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Mechanical Engineering Physics Public Health Social Sciences Transportation Other

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Journal : Journal of Bio-molecule Research And Engineering

 1 
Evaluation on Bioactive Secondary Metabolites from Fingerroot (Boesenbergia rotunda) as a Potent α-Glucosidase Inhibitor: In silico Study: In silico Study Firdaus, Yazdaniar Fajri Halimi; Hariyanto, Nova Alfian; Kurnia, Irmayanti Tri; Lestari, Dinda Ayu; Suwandari, Suhartini; Haq, Kautsar Ul; Phuwapraisirisan, Preecha; Ramadhan, Rico
Journal of Bio-Molecule Research and Engineering Vol 2 No 1 (2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbiome.v2i1.51981

Abstract

Fingerroot (Boesenbergia rotunda) is a medicinal plant that has been reported to have anti-diabetic properties. However, the mechanism of action and the active compounds responsible for this effect are not well understood. In this study, we performed molecular docking study of isolated compound from fingerroot against N-terminal-human intestinal maltase-glucoamylase, one class of α-glucosidase. Inhibiting enzymatic activity of alpha glucosidase could potentially control sugar levels. In addition to panduratin A showing moderate inhibition activity against N-terminal-human intestinal maltase-glucoamylase.
Evaluation potency of Boesenbergia rotunda as antioxidant achieved by free radicals scavenging activities Dinda; Kurnia, Irmayanti Tri; Hariyanto, Nova Alfian; Suwandari, Suhartini; Firdaus, Yazdaniar Fajri Halimi; Mahmuda, Nur Fariha; Phuwapraisirisan, Preecha; Ramadhan, Rico
Journal of Bio-Molecule Research and Engineering Vol 2 No 1 (2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbiome.v2i1.52066

Abstract

Boesenbergia rotunda has antioxidant potential to inhibit free radicals. Antioxidant activity was determined by free radical scavenging activity against DPPH, ABTS and Cuprac. The results showed that the hexane extract of Boesenbergia rotunda had a strong percent antioxidant activity with a value of 91.38, while ascorbic acid as a positive control had a value of 99.85. Antioxidant activity test results showed that hexane and dichloromethane extracts have DPPH, ABTS, and cuprac free radical scavenging activities
Assessment of the Phytochemicals and Antioxidant Activity of Baccaurea bracteata Müll.Arg. and Macaranga lowii King ex Hook.f. from East Kalimantan Dinda; Suwandari, Suhartini; Kurnia, Irmayanti Tri; Hasan, Muhammad Iqbal; Artama, Riro Iraga; Phontree, Kiettipum; Ramadhan, Rico
Journal of Bio-Molecule Research and Engineering Vol 2 No 2 (2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbiome.v2i2.65361

Abstract

This study investigated the total phenolic content and antioxidant activity of Baccaurea bracteata Müll.Arg. and Macaranga lowii King ex Hook.f. from East Kalimantan. The leaves of these plant extracts were evaluated for their total phenolic content (TPC) and antioxidant activity, utilizing the DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay. The findings indicated that Baccaurea bracteata Müll.Arg. demonstrated superior antioxidant activity with a percent inhibition (PI) value of 68.31 ± 0.11%. This research highlights Baccaurea bracteata Müll.Arg. as a promising source of natural antioxidants, characterized by high total phenolic content of 14.76 ± 1.98 mgGAE/g.
Co-Authors A. Budi Prasetyo Abdjan, Muhammad Ikhlas Ahlan Riwahyu Habibi Ahmadi Jaya Permana Al Fatiha, Nazwa Putri Alamsyah, Jumadil Aldrisya Alfa Akustia Widati Alfinda Novi Kristanti Andika Pramudya Wardana Aning Purwaningsih Ardana, M. Tara Mico Artama, Riro Iraga Atik Widiyanti Aulianitha Salsabella Baharin, Siti Nor Atika Bayu Susetya Ananda Budi Prasetyo, Antonius Dinda Dyah Ayu Dewi Listyaningrum Enih Rosamah Enos Tangke Arung, Enos Tangke Fania, Azzahra Fatiha Khairunnisa fatimah Fatimah Firdaus, Yazdaniar Fajri Halimi Handoko Darmokoesoemo Haq, Kautsar Ul Hariyanto, Geraldo Figo Hariyanto, Nova Alfian Harsasi Setyawati Hartati Hartati Hasan, Muhammad Iqbal Irawan Wijaya Kusuma, Irawan Wijaya Juniar, Muhammad Althof Kariza Makanty Kautsar Ul Haq Khoso, Mir Hasan Kurnia, Irmayanti Tri Lestari, Dinda Ayu Mahmuda, Nur Fariha Miratul Khasanah Mochamad Zakki Fahmi Mulyadi Tanjung Nanik Siti Aminah Ni'matuzahroh, Ni'matuzahroh Nur Chamidah Nurliana Phontree, Kiettipum Phuwapraisirisan, Preecha Pujiati Pujiati Purba, Dwiky Julius Purkan Purkan Qurrota A’yuni Rahmadani, Nisfa Amalia Rambe, M. Sofyan Sauri Rimuljo Hendradi Rudi Kartika, Rudi Rudianto Amirta Saragih, M. Setya Perdana Sarah Azzara Dikarulin Sholikhah, Oktaviariesta Habibatus Simbolon, Hasanal Fachri Satia Siti Wafiroh Sofijan Hadi Sri Sumarsih Sri Utami Subur P Pasaribu Suhaili, Suhaili Suwandari, Suhartini Suwinarti, Wiwin Takaya, Yoshiaki Tasya Ananda Putri Tio Christiawan Bramayudha Tokok Adiarto Tokok Ardiarto Ulya, Diana Wardana, Andika Pramudya Yanuardi Raharjo, Yanuardi Yuliansyah Yuliansyah