Article Per Year (5 Year)
p-Index From 2021 - 2026
3.006
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Jurnal Kartika Kimia Journal of Midwifery and Nursing JFIOnline JCPS (Journal of Current Pharmaceutical Sciences) JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi Pharmacoscript ad-Dawaa : Journal of Pharmaceutical Sciences Science Midwifery Jurnal Buana Farma Jurnal Abdimas Kartika Wijayakusuma Journal of Science and Technology Research for Pharmacy Jurnal Farmasi Indonesia Kartika : Jurnal Ilmiah Farmasi Jurnal Kefarmasian Indonesia
Suci Nar Vikasari, Suci Nar
Fakultas Farmasi, Universitas Jenderal Achmad Yani, Cimahi, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 29 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Pharmacoscript

 1 
THE EFFECTS OF ARABICA COFFEE (Coffea arabica) FRUIT SKIN FERMENTED WITH KOMBUCHA ON NICOTINE-DEPENDENT MICE Fahmy Ahsanul, Haq; Suci Nar, Vikasari; Muhamad Ridho, Maulana
Pharmacoscript Vol. 9 No. 1 (2026): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v9i1.2763

Abstract

Nicotine is an addictive substance in cigarettes that causes dependence, making it difficult for smokers to quit. Treatment for nicotine dependence has limitations in terms of low effectiveness and side effects. Alternative treatments based on natural ingredients, such as coffee fruit skin or cascara (CA), which is rich in polyphenols, flavonoids, caffeine, and chlorogenic acid, offer neuroprotective potential to reduce nicotine dependence with minimal side effects. Fermentation using kombucha (KO) can increase the content of these bioactive compounds. This study aims to evaluate the effect of cascara fermented with kombucha on mice experiencing nicotine dependence. The study used a Conditioned Place Preference (CPP) design in male Swiss Webster mice induced by nicotine at a dose of 0.5 mg/kg BW. The test animals were given cascara and cascara-kombucha preparations at the same dose of 0.65 mL/20 g BW orally. In the pre-test stage, the initial residence time of the mice in each compartment was measured for baseline preference. The conditioning phase was conducted by administering test preparations and nicotine to selected compartments. The post-test measured the residence time in the nicotine compartment for 15 minutes. The CPP score was calculated as the difference between the post-test and pre-test residence times. Cascara and cascara-kombucha produced lower CPP scores than the nicotine group. Cascara-kombucha showed a better effect with a lower CPP score than cascara alone. Fermented cascara kombucha has suggested potential as an alternative therapy to overcome nicotine dependence.
Co-Authors Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah B. Sutjiatmo Afifah Bambang Sutjiatmo Afifah Bambang Sutjiatmo, Afifah Bambang Aisyah, Salmanda Akhirul Kahfi Syam Ambarsundari Ambarsundari Andi Supriatna Andri R. Rahmadi Andri Reza Rahmadi Anna Choirunnisa, Anna Ari Sri Windyaswari, Ari Sri Asri Wulandari Astuti, Niken Juni Ayu Nurfitiria Rahmi Ayu Nurfitiria Rahmi, Ayu Nurfitiria Bintussolihah, Falna Candra Candra Candra candra Dewi Lidya Ichwana Nasution Dwi Yuliana Prasita Dzikrial Sa’id Elin Yulinah ELIN YULINAH SUKANDAR Elin Yulinah Sukandar Elin Yulinah Sukandar Elivas Simatupang Elivas Simatupang Encep Abdurahman Fahmy Ahsanul, Haq Faizal Hermanto Febrinella, Catellya Fikri Alatas Grace S. Mardiana Hanna Sari Widya Kusuma, Hanna Sari Widya Haq, Fahmy Ahsanul Hartyana Sutarna, Titta Ita Nur Anisa Ita Nur Anisa Khansa Rana Khalifa Kristian, Randi Kuatrina Kuatrina Kuatrina, Kuatrina Kusmaningati, Suswini Kusmayadi, Anandita Tiara Kusumawardhana, Gelar Taufiq Lucky Rachmawan Lucky Rachmawan Melani, Beta Muhamad Ridho, Maulana Nengdiana Permana Niken Juni Astuti Nindy Dwi Siftiani Novia Anggraeni Hanafi Novia Anggraeni Hanafi, Novia Anggraeni Oskar Skarayadi, Oskar Pudjiastuti Kartidjo Pudjiastuti Kartidjo Puput Ayu Perdana Puput Ayu Perdana, Puput Ayu Purwoko, Agus Puspa Sari Dewi Solihah Rachmawan, Lucky Raden Mohamad Herdian Bhakti Rahajeng, Dea Julianti Ramadhan Muhamad Syahrul Redya Hernawati Redya Hernawati, Redya Regita Ayu Lestari Ririn Puspadewi Ririn Puspadewi, Ririn Ririn Sinaga Ririn Sinaga, Ririn RR. Ella Evrita Hestiandari Salmanda Aisyah Setiani, Nur Asni Sheba, Shiane Hanako Shifa A. Savitri Siftiani, Nindy Dwi Simatupang, Elivas Solihah, Puspa Sari Dewi Solihat, Ananda Khairunisa Soraya Riyanti, Soraya Sri Wahyuningsih Sujiatmo, Afifah Bambang Sulaeman Al Jati Supito, Sarasvati Sekar Ayu Suryani Suryani Suryani Sutandi Tatan Syarifuddin Syarifuddin Syarifuddin Syarifuddin Syifa Khoirunnisa, Syifa Tupak, Helma Malini Marol Vina Septiani, Vina WAHYU WIDOWATI Wita Anggraeni Wulan Anggraeni Yulia Ratnawati, Yulia Yulianti, Maulidya Yuliartati, Ni Luh Ade Zahiroh, Fadhilah Haifa