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Journal : Jurnal Natural

Potential side effects of medicine on patients with tuberculosis fixed-dose combination in dr. Pirngadi Hospital, Medan EVA SARTIKA DASOPANG; FENNY HASANAH; IDA FAUZIAH; SALMAN SALMAN; TEDY KURNIAWAN BAKRI
Jurnal Natural Volume 20 Number 1, February 2020
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.045 KB) | DOI: 10.24815/jn.v20i1.15285

Abstract

Tuberculosis is caused by the bacterium Mycobacterium tuberculosis, which by only using a few new antibiotics, can kill the bacteria. Tuberculosis treatment has several stages, namely intensive and advanced stages. Compliance with the use of OAT is an imported factor in the success of TB treatment. The use of many drugs can cause side effects that result in patients stopping treatment when it creates the TB treatment process to fail. Improved adherence can do by using a fixed-dose combination OAT. In the intensive phase, the patient will get a fixed-dose combination containing a mixture of four antibiotics. The purpose of this study is to evaluate the potential side effects that occur during fixed-dose combination OAT treatment at an intensive stage and see the level of compliance of patients taking TB drugs. Observational sampling in TB patients was taking OAT at an acute stage by looking at side effects that arise during treatment and then analyzed using statistics and algorithm Naranjo. The results showed the most common potential side effects for fixed-dose combination OAT in the intensive stage were itching, headache and nausea with a percentage of 72% each, joint pain 45%, stomach pain 36.4%, lack of appetite and rashes 27.3% each and reddish color in the urine 18.2%. The results of the analysis using Naranjo logarithm obtained results eight, which means the side effects might cause due to the use of the drug. The results of patient compliance achieved a 100% compliance rate
Potential side effects of medicine on patients with tuberculosis fixed-dose combination in dr. Pirngadi Hospital, Medan EVA SARTIKA DASOPANG; FENNY HASANAH; IDA FAUZIAH; SALMAN SALMAN; TEDY KURNIAWAN BAKRI
Jurnal Natural Volume 20 Number 1, February 2020
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v20i1.15285

Abstract

Tuberculosis is caused by the bacterium Mycobacterium tuberculosis, which by only using a few new antibiotics, can kill the bacteria. Tuberculosis treatment has several stages, namely intensive and advanced stages. Compliance with the use of OAT is an imported factor in the success of TB treatment. The use of many drugs can cause side effects that result in patients stopping treatment when it creates the TB treatment process to fail. Improved adherence can do by using a fixed-dose combination OAT. In the intensive phase, the patient will get a fixed-dose combination containing a mixture of four antibiotics. The purpose of this study is to evaluate the potential side effects that occur during fixed-dose combination OAT treatment at an intensive stage and see the level of compliance of patients taking TB drugs. Observational sampling in TB patients was taking OAT at an acute stage by looking at side effects that arise during treatment and then analyzed using statistics and algorithm Naranjo. The results showed the most common potential side effects for fixed-dose combination OAT in the intensive stage were itching, headache and nausea with a percentage of 72% each, joint pain 45%, stomach pain 36.4%, lack of appetite and rashes 27.3% each and reddish color in the urine 18.2%. The results of the analysis using Naranjo logarithm obtained results eight, which means the side effects might cause due to the use of the drug. The results of patient compliance achieved a 100% compliance rate
Co-Authors Adinda Utami Agung Suharyanto Aisyah , Teti Akmal Simutuah Akmal Simutuah, Akmal Almunadia , Annisa Almunadia, Annisa Anggreini, Dea Anna Juniar Arianti, Nova Ariyanti Kesuma Wardani Arya Tata Prianka Boy Eric Hutabarat Chairul Nisak Dara Santika Daya, Verawati L. Dea Anggraini Debi Meilani Dessy Natalia Siahaan Desy Natalia Siahaan Desy Natalia Siahaan Desy Natalia Siahaan Dhafi, Muhammad Dinda Siti Sakila Emilia Hasibuan, Emilia Ernawaty Ginting Fatia Zahra Fenni Hasanah FENNY HASANAH Fenny Hasanah Fujiko, Muflihah Hajatina Hajatina Handayani Lubis , Salma Handayani Lubis , Salmah Handayani Lubis, Salma Handayani, Salmah Harefa, Niken Septriani Hasanah , Fenny HASANAH, FENNY Hasanah, Fenny IDA FAUZIAH Ida Fauziah, Ida Ika Julianti Tambunan Intan Purnama Sari Irnabila, Salsa Jamilah Nasution Julia Sari, Tahara Kamila, Tazkia Karolina Sitepu Karuna Affa Ade Dea Lathifur Rasyidah Tanjung Lince, Verawati Linda Margata Lubis, Salmah Handayani Lubis, Salmah Handayani Lubis Mariany Razali Mariany Razali Maulida Maulida Muflihah Fujiko Muflihah Fujiko Muharni Saputri Muliani, Wina Nadia Nuzulia Nadia, Syarifah Naswa, Shinta Natalia Siahaan , Desy Ndruru, Mei Kasih Murni Nerdy Nilsya Febrika Zebua, Nilsya Febrika Nova Arianti Nurmala Sari Nuzulia , Nadia Nuzuliai, Nadia Pahmi, Latipah Pane , Ramona Paradina Hayu Ningtyas Pravil Mistryanto Tambunan Putri Aisyah Perbrianti Rahayu, Rina Gusti Ramzayani, Astuti Rasyida Lubis, Dina Yunisma Ratih Paramitha Razali Razali Rini Agnesia Ndruru Rosandra, Cinta Salmah Handayani Lubis salmah handayani Lubis Salman Salman Sandika, Thalita Saputri, Muharni Saputri, Muharni Septi Noiman Lase Shinta Naswa Siahaan , Desy Natalia Siahaan, Desy Natalia Sihotang, Supran Hidayat siti muliani julianty Siti Rahmi Ningrum siti rahmi ningrum Siti Syarah Solly Aryza Sulaini Maspin Sumardi Supomo Supran Hidayat Supran Hidayat Sihotang Susi Ari Kristina Syarah, Siti Syarifah Nadia TEDY KURNIAWAN BAKRI Thaharah, Yelda R. Thaharah, Yelda Ratu Thalita Sandika Utami, Adinda Verawati Lince Vriezka Mierza Yelda Ratu Thaharah Yessi Febriani Yessi Febriani Yessy Febriani Yuni M , Yohana