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All Journal Jurnal Teknologi Dan Industri Pangan Berkala Ilmiah Kedokteran Duta Wacana Jurnal Gizi dan Pangan Soedirman (JGPS) Marinade GHIDZA: Jurnal Gizi dan Kesehatan Jurnal Kesmas dan Gizi (JKG) JURNAL FARMASIMED (JFM) Best Journal (Biology Education, Sains and Technology) CITIZEN: Jurnal Ilmiah Mulitidisiplin Indonesia Jurnal Teknologi Pengolahan Pertanian Jurnal Pengmas Kestra (JPK) Journal of Pharmaceutical and Sciences.
Reno Irwanto
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : JURNAL FARMASIMED (JFM)

 1 
ANTIBACTERIAL EFFECTIVENESS TEST OF KECOMBRANG LEAVES (ETLINGERA ELATIOR) ETHANOL EXTRACT ON THE GROWTH OF PROPIONIBACTERIUM ACNES Wati, Siska; Irwanto, Reno; Cholilulah, Andreais Boffil
Jurnal FARMASIMED (JFM) Vol 5 No 1 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i1.1367

Abstract

Propionibacterium acnes merupakan salah satu flora normal pada kulit yang berperan dalam timbulnya jerawat. Bila jumlahnya meningkat bakteri ini akan menjadi patogen dan menimbulkan lesi inflamasi pada kulit. Alternatif yang dapat dilakukan adalah dengan memanfaatkan bahan alamsebagai antibakteri yaitu tanaman kecombrang (Etlingera elatior). Tujuan dari penelitian ini adalahuntuk mengetahui efektivitas antibakteri ekstrak etanol daun kecombrang (Etlingera elatior) terhadappertumbuhan bakteri Propionibacterium acnes. Penelitian ini dilakukan dengan mengekstrak daunkecombrang (Etlingera elatior) dengan metode ekstraksi maserasi menggunakan etanol 96%. Metode: Uji daya hambat dilakukan dengan metode difusi cakram. Sampel terdiri dari 6 perlakuanyaitu ekstrak etanol daun kecombrang dengan konsentrasi 20%, 15%, 10%, 5%, kontrol positif DMSO dan kontrol negatif clindamycin. Hasil penelitian menunjukan ekstrak etanol daun kecombrang dengankonsentrasi 20% mempunyai daya hambat sebesar 20,0 mm (kategori kuat), 15% sebesar 13,5 mm (kategori kuat), 10% sebesar 9,0 (kategori sedang), 5% sebesar 6,0 (kategori lemah). Kesimpulanpenelitian ini adalah daya hambat antibakteri terhadap bakteri Propionibacterium acnes dengankonsentrasi paling efektif adalah 20% dengan kategori kuat 20,0.
TRANSPARENT SOAP FORMULATION WITH VARIOUS LEVELS OF CONCENTRATION OF TEAK LEAF EXTRACT (TECTONA GRANDIS L.F.)AS ANTIBACTERIAL SOAP Pranata, Chandra; Irwanto, Reno; .S, Aminah
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1401

Abstract

The purpose of this study was to examine the organoleptic, homogeneity and antibacterial properties of transparent soap. The treatment used is; F1 (3% teak leaf extract), F2 (6% teak leaf extract), F3 (9% teak leaf extract), and F4 (12% teak leaf extract). The implementation of the research begins with product optimization in advance of the proportion of the use of raw material components. The results of the homogeneity test experiment showed that all formulas were homogeneous and in accordance with SNI standards, then the results of the water content obtained from each preparation proved to meet the requirements set by SNI ( Indonesian National Standard). The results of the pH measurements showed that at pH F0 it remained at 8. The results for measuring pH F1 showed results with a pH of 8. Meanwhile, pH F2 had a pH of 8. The last measurement for pH at pH F3 showed the same pH results as the other formula, namely at pH 8. So that F0, F1, F2, and F3 have the same pH, namely pH 8, where pH 8 is the pH of the positive control, namely soap on the market. Staphylococcus aureus with a concentration of 3% by 13 mm, 6% by 15 mm, 9% by 17 mm, 12% by 20 mm. The greater the concentration of teak leaf extract in transparent solid coir, the greater the inhibition of bacterial growth.
ETHANOL EXTRACT LIQUID SOAP FORMULATION LEAVES OF CELERY (Apium graveolens L.) AGAINST Escherichia coli BACTERIA Irwanto, Reno; Apriani Girsang, Santa Dewi; Maria Ginting, Wira; Novia, Reni
Jurnal FARMASIMED (JFM) Vol 5 No 2 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v5i2.1584

Abstract

Dirty hands will be a source of disease. Soap is a pharmaceutical preparation used to maintain health. Celery (Apium graveolens L.) is a plant of the Apiaceae tribe with a distinctive menthol aroma. This study aimed to determine the inhibitory power of celery leaf extract formulation (Apium graveolens L.) as an antibacterial hand-washing soap. This research method is a type of experimental research. The stages of the research were collecting samples, identifying plants, making simplicia, characterizing simplicia, screening phytochemicals, making extracts and making hand soap formulations of celery leaf extract (Apium graveolens L) at concentrations of 5%, 10%, 15% and antibacterial testing of celery leaves, against Escherichia coli bacteria. The results showed the celery leaf extract soap formulation contained phytochemical compounds of flavonoids, tannins and saponins. The organoleptic test found that the best soap formulation was the F2 formulation with a concentration of 10% at an average level of preference value, namely 3.67 for colour, 3.27 for aroma, and 3.80 for texture. The homogeneity test performed showed that all formulations produced soap with good homogeneity. The height and stability test of the resulting celery extract soap foam ranged from 61-71 mm. The irritation test of the resulting celery extract soap also showed no irritation for all the formulations. The value of the antibacterial activity test found that the F1 formulation showed antibacterial activity with an inhibition zone diameter of 3 (weak), F2 with an inhibition zone of 9 (moderate) and F3 with the antibacterial activity of 12 (strong).
ORGANOLEPTIC TESTS AND ANTIOXIDANT ACTIVITY OF BLACK SOYBEAN (GLYCINE SOJA L) SUPPLEMENTED TAMARILLO(SOLANUM BETACEUM CAV) Irwanto, Reno; Novia, Reni; Rantika, Windy
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1952

Abstract

Degenerative disease refers to metabolic syndrome which occurs as a result of an unhealthy lifestyle. An unhealthy diet results in the emergence of large amounts of free radicals. High free radical content can disrupt cells and their genetic material which can result in degenerative diseases. Antioxidants are compounds that function to protect body cells from damage caused by free radicals that cause degenerative diseases. Soybean juice added with tamarillo is a food ingredient that is a source of antioxidants. The aim of the research was to obtain the best Dutch eggplant formula added to soy milk. The research method used was a Completely Randomized Design (CRD) which involved four additional treatments of Dutch eggplant, namely P1 (50 mL), P2 (55 mL), P3 (60 mL) and P4 (65 mL). Research activities were initially carried out by testing the organoleptic products using the hedonic method by 70 untrained panelists. Product testing is carried out using Then the best product testing results are continued to be tested for antioxidant content. Antioxidant testing The results of the organoleptic test research obtained the highest scores for the color attribute 5.69 (P3), aroma 5.23 (P2), taste 6.09 (P1), texture 4.76 (P1), and overall 5.81 (P1). Based on organoleptic tests, the best formula is 60 mL (P3) then the antioxidant activity test is 0.3374 ppm. The conclusion in this study shows that the best formula in terms of color, taste and overall black soybean juice added with Dutch eggplant has significant antioxidants.
Utilization of Cinnamon Leaves (Cinnamomum burmannii, Blume) and Effectiveness Test as Mouthwash against Oral Microbes Octora, Debi Dinha; Irwanto, Reno; Simarmata, Pratiwi Christa
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2287

Abstract

Oral health is an important aspect to pay attention to because it is part of the digestive system. Disorders in oral health function can impact other bodily health. The use of mouthwash is necessary to improve the cleanliness and health of the mouth, especially when brushing alone is not optimal. The active compounds in mouthwash enhance cleanliness and effectively inhibit the growth of pathogenic oral microflora. Cinnamon leaves have not been widely utilized and are often left unused or discarded. Previous research has been conducted on the potential of the compounds in cinnamon leaves. This research was carried out by determining the best essential oil content of cinnamon leaves through several preliminary treatments and varying distillation times. Active compounds such as cinnamaldehyde, L-linalool, and cinnamyl acetate were found in the cinnamon leaves, making them a potential ingredient for mouthwash formulation. The aim of this study is to produce an effective mouthwash that reduces the growth of pathogenic oral microflora using underutilized local materials. The mouthwash preparation method was modified from several active ingredient mouthwash preparation methods by varying the concentration of cinnamon leaf essential oil at 5%, 10%, and 15%. The formulations were then evaluated for organoleptic properties, stability, homogeneity, and antibacterial activity against S. mutans using the disc diffusion method. The results showed that the preparations remained physically stable and homogeneous during 30 days of storage at room temperature. The cinnamon leaf mouthwash exhibited antibacterial activity against S. mutans, with average inhibition zones of 15.25 mm, 19.06 mm, and 24.34 mm for formulations I, II, and III, respectively. Based on these results, it can be concluded that the cinnamon leaf mouthwash has the potential to inhibit the growth of S. mutans bacteria."
Co-Authors .S, Aminah Agnes Tresya Nababan Alberta Dame Yanti Zega Andreais Boffil Cholilluloh Andreais Boffil Cholilullah Andreais Boffil Cholilullah Andreais Boffil Cholilulloh Anggi Isnani Paranduri Anggraini, Citra Dewi Anwar Kasim Apriani Girsang, Santa Dewi Br Ginting, Luci Riani Chandra, Putra Cholilulah, Andreais Boffil Claudia, Dinda Dede Robiatul Adawiyah Delita Br Panjaitan Desri Meriahta Girsang Didit Hadisiswaya Fadlilah Widyaningsih Feberlian Ndruru Fransiska Rungkat Zakaria Ghefira Ghaetsa, Alda Ginting, Luci Riani Ginting, Wira Maria Herviana, Herviana Hurriyyatun Kabbaro Jelita Manurung Jumsurizal Jumsurizal Keleng Ate Ginting Manurung, Jelita Maria Ginting, Wira Marwita Pratiwi Nainggolan Maya Indra Rasyid Meria Turnip Meriahta Br Girsang Nadia Husna Nadia Husna Nanda Triandita Nanda Triandita, Nanda Nela Eska Putri, Nela Eska Nisya Ayu Rachmawati Novia, Reni Nugraheni, Prastiti Laras Nyimas Rupiah Octora, Debi Dinha Pasaribu, Sudana Fatahillah Pranata, Chandra Pratiwi Christa Simarmata Putra Chandra Raini Panjaitan Rantika, Windy Ratna Sari Dinaryanti Reni Novia Risda Situmorang Risdi, Ardila Sahadi Didi Ismanto Sahrul Diansyah Salmi Angraini Siregar, Annisa Febriana Siregar, Wilda Wahyuni Siska Wati, Siska Sri Novalina Sudana Fatahillah Pasaribu Supriyadi Supriyadi Wira Maria Ginting Yessy Arisman Yessy Arisman Yolanda Fortuga, Nia Yolanda Pane