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All Journal Journal of Food and Pharmaceutical Science Biology, Medicine, & Natural Product Chemistry MPI (Media Pharmaceutica Indonesiana) Sebatik Jurnal Mandala Pharmacon Indonesia Kumawula: Jurnal Pengabdian Kepada Masyarakat Reswara: Jurnal Pengabdian Kepada Masyarakat Jurnal Mandala Pengabdian Masyarakat Indonesian Community Journal JURNAL BIOLOGI PAPUA Riset Informasi Kesehatan Amal Ilmiah: Jurnal Pengabdian Kepada Masyarakat Journal of Food and Pharmaceutical Sciences ABDI UNISAP: Jurnal Pengabdian Kepada Masyarakat GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Sains dan Kesehatan Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Claudius Hendraman B. Tobi
Universitas Cenderawasih
Religion Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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SYNTHESIS AND ANTIOXIDATION OF AVOCADO (Persea Americana) LEAVES EXTRACT BY ABTS METHOD IN VITRO Yustisia Dian Advistasari; Novi Elisa; Wulan Kartika Sari; Ainun Fawaid; Dhimas Adhityasmara; Claudius Hendraman B. Tobi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 13 No. 1 (2026)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

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Abstract

Antioxidants play a role in inhibiting the development of metabolic syndrome, which is associated with several diseases. Increased free radical production can cause the body's system to require support from other antioxidants. The use of synthetic antioxidants is still limited due to their potential side effects. Natural antioxidants from natural ingredients, such as Avocado leaves, are needed. The purpose of this study was to determine compounds with antioxidant potential by testing the synthesis and bioequivalence of Avocado leaves extract in Vitro. The research methods used were Fourier Transform Infrared (FTIR) spectroscopy, Gas Chromatography-Mass Spectrometry (GC-MS), and ABTS assay. The results of the FTIR analysis of the Avocado leaves extract showed that the functional groups of organic compound molecules were N-H, H-C=O, C=C, C-O-H, and C-N. This result indicated that the Avocado extract contained phenolic compounds. GC-MS analysis result showed that the phytochemical components with the highest abundance in the Avocado leaves extract were the compounds at peak numbers 1 and 4, namely 9-Octadecenoic acid (Z)-, methyl ester (CAS) and 9-Octadecenoic acid (Z)-(CAS). Antioxidant test showed a linear regression equation of y = 0.267x + 35.007, R2 = 0.9491. This linear regression equation can be interpreted as a very strong and positive correlation. The IC50 value of Avocado leaves extract was 56.154, that categorized as a very strong antioxidant property. So it can be said that Avocado leaves extract has potential as an antioxidant.
SYNTHESIS AND ANTIOXIDATION OF AVOCADO (Persea Americana) LEAVES EXTRACT BY ABTS METHOD IN VITRO Yustisia Dian Advistasari; Novi Elisa; Wulan Kartika Sari; Ainun Fawaid; Dhimas Adhityasmara; Claudius Hendraman B. Tobi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 13 No. 1 (2026)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antioxidants play a role in inhibiting the development of metabolic syndrome, which is associated with several diseases. Increased free radical production can cause the body's system to require support from other antioxidants. The use of synthetic antioxidants is still limited due to their potential side effects. Natural antioxidants from natural ingredients, such as Avocado leaves, are needed. The purpose of this study was to determine compounds with antioxidant potential by testing the synthesis and bioequivalence of Avocado leaves extract in Vitro. The research methods used were Fourier Transform Infrared (FTIR) spectroscopy, Gas Chromatography-Mass Spectrometry (GC-MS), and ABTS assay. The results of the FTIR analysis of the Avocado leaves extract showed that the functional groups of organic compound molecules were N-H, H-C=O, C=C, C-O-H, and C-N. This result indicated that the Avocado extract contained phenolic compounds. GC-MS analysis result showed that the phytochemical components with the highest abundance in the Avocado leaves extract were the compounds at peak numbers 1 and 4, namely 9-Octadecenoic acid (Z)-, methyl ester (CAS) and 9-Octadecenoic acid (Z)-(CAS). Antioxidant test showed a linear regression equation of y = 0.267x + 35.007, R2 = 0.9491. This linear regression equation can be interpreted as a very strong and positive correlation. The IC50 value of Avocado leaves extract was 56.154, that categorized as a very strong antioxidant property. So it can be said that Avocado leaves extract has potential as an antioxidant.
Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of Areca Nut Ethanolic Extract Against Streptococcus mutans and Escherichia coli using Broth Dilution Method Adrianz Mario Tethool; Claudius Hendraman B. Tobi; Mustika Endah Pratiwi
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.1037-1044

Abstract

Antimicrobial Resistance (AMR) is the global problems that continously develop. Two bacteria that are the most pathogenic are Streptococcus mutans (S. mutans) and Escherichia coli (E. coli). The AMR requires new strategies to address this health problem, including the development of new drugs from natural products. Through this study, we aimed to discovering the antibacterial activity of Areca Nuts against S. mutans and E. coli as potential new antibiotics from natural products. The study begin with extration process, then continued with characterization of extract, bacteria identification, and determination of Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). This study obtained the yield percentage of extract was qualified the standard reference (28.95%). The characterization of extract showed the extract meet the qualification based on loss on drying, water content, ash content and total count plate parameters. The MIC values of Areca Nut ethanolic extract against S. mutans is 250 ppm and against E. coli is 62.5 ppm. The MBC values of Areca Nut ethanolic extract against S. mutans is 500 ppm and against E. coli is 62.5 ppm. The result show the ethanol extract of areca nut seeds has antibacterial activity with bactericidal properties, where the ethanol extract of areca nut seeds is more effective against E. coli bacteria than S. mutans bacteria.
Edukasi Perencanaan Menu Berdasarkan Prinsip Gizi Seimbang bagi Lansia dengan Hipertensi di Panti Bina Lanjut Usia Pos 7 Sentani Elisabet Bre Boli; Titi Afelya; Dwi Astuti; Mustika Endah Pratiwi; Claudius Hendraman B. Tobi
ABDI UNISAP: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 2 (2023): ABDI UNISAP: Jurnal Pengabdian Kepada Masyarakat
Publisher : UPT Publikasi dan Penerbitan Universitas San Pedro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59632/abdiunisap.v1i2.169

Abstract

Kebutuhan gizi lansia akan meningkat sejalan dengan peningkatan kejadian sakit, seperti hipertensi. Hipertensi pada lansia membutuhkan lebih banyak perhatian, terutama dalam hal asupan gizi sehari-hari. Panti Bina Lanjut Usia Pos 7 sebagai institusi bagi lansia masih menerapkan prinsip 4 sehat 5 sempurna dalam perencanaan menu. Penting dilakukan perbaikan perencanaan menu gizi seimbang bagi lansia dengan hipertensi. Kegiatan ini bertujuan agar peserta mampu menyusun menu gizi seimbang bagi lansia dengan hipertensi di Panti Bina Lansia Pos 7 Sentani. Metode kegiatan adalah edukasi face to face dan diskusi, serta praktik penyusunan menu. Sasaran kegiatan adalah . Kegiatan akan dilaksanakan dalam 4 tahapan, yaitu advokasi terhadap pihak Panti Bina Lansia Pos 7 Sentani, survei ketersediaan pangan, penerapan perencanaan menu, dan monitoring serta evaluasi. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan keterampilan menyusun menu gizi seimbang para penjamah makanan di Panti Bina Lansia Pos 7 melalui pemberian edukasi. Penjamah makanan Panti Bina Lansia Pos 7 menyusun menu bergizi seimbang selama 3 hari yang terdiri dari makanan-makanan lokal. Meskipun demikian, keberadaan ahli gizi perlu untuk terus memantau perencanaan gizi seimbang yang tepat bagi seluruh lansia dan masalah kesehatan yang dialaminya.
Penguatan Literasi dan Numerasi Anak melalui Permainan Edukatif Kartu Huruf dan Kartu Matematika Sitti Rosnafian Sumardi; Muhammad Hisyam; Mustika Endah Paratiwi; Chlara Thesalonica Luanmasa; Lorenso Apriyanto Bria; Tamara Louraine Jeanette Kainama; Anita Pratiwi; Claudius Hendraman B Tobi; Winda Ade Fitriya B; Febby Seru
I-Com: Indonesian Community Journal Vol 6 No 1 (2026): I-Com: Indonesian Community Journal (Maret 2026)
Publisher : Fakultas Sains Dan Teknologi, Universitas Raden Rahmat Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/i-com.v6i1.9380

Abstract

Penguatan literasi dan numerasi anak sangat penting untuk meningkatkan kualitas pendidikan dasar di Papua. Kegiatan pengabdian masyarakat ini dilaksanakan di Rumah Baca Ayapo, Sentani Timur, Papua, pada 4 dan 12 Juli 2025 dengan melibatkan 26 anak. Metode pelaksanaan dilakukan secara terstruktur melalui tiga tahapan utama: (1) Tahap persiapan, meliputi koordinasi mitra, penyusunan aturan permainan, dan instrumen evaluasi; (2) Tahap pelaksanaan, menggunakan pendekatan partisipatif, demonstratif, dan pelatihan (learning by doing) melalui permainan edukatif kartu huruf serta kartu matematika (MathemaCard: Duel Berhitung); dan (3) Tahap evaluasi, untuk mengukur capaian kognitif serta observasi perilaku afektif. Teknik pengukuran hasil menggunakan instrumen pre-test dan post-test sederhana serta wawancara singkat . Hasil kegiatan menunjukkan peningkatan signifikan pada skor rata-rata literasi (25% menjadi 75%) dan numerasi (20% menjadi 70%). Selain aspek kognitif, media ini efektif meningkatkan rasa percaya diri, motivasi belajar, dan keterampilan sosial anak. Media ini merupakan solusi inovatif yang mudah direplikasi untuk komunitas lokal.
EDUKASI PENANGGULANGAN PENYALAHGUNAAN OBAT DAN MANFAAT KONSUMSI TABLET TAMBAH DARAH PADA REMAJA SMP YPPK ST. PAULUS ABEPURA Mustika Endah Pratiwi; Graciano Aristides Maturbongs; Claudius Hendraman B. Tobi; Andre Anusta Barus; Felycitae Ekalaya Appa; Yohana Krisostoma Anduk Mbulang; Juniarto Mende
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 06 (2025): DESEMBER 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Beberapa fenomena yang marak terjadi di Indonesia terkait perkembangan remaja diantaranya adanya fenomena buruk dari penyalahgunaan NAPZA dan kejadian anemia pada remaja putri. Sasaran kegiatan pengabdian kepada masyarakat ini Adalah siswa-siswi SMP YPPK St. Paulus Abepura kelas VII dengan usia sekitar 13-14 tahun. Adanya kegiatan ini diharapkan dapat memberikan informasi kesehatan yang komprehensif kepada siswa-siswi mengenai penanggulangan penyalahgunaan NAPZA dan pentingnya konsumsi tablet tambah darah pada remaja. Kegiatan pengabdian ini dilakukan melalui metode penyuluhan kelompok. Dalam kegiatan penyuluhan, peserta terlihat antusias dan aktif dapat dilihat dari peserta yang menyimak, mencatat materi penyuluhan, memberikan pertanyaan serta membagikan pengalaman mereka dalam penyalahgunaan NAPZA dan pengalaman terkait anemia dan konsumsi tablet tambah darah. Hasil evaluasi kegiatan menunjukkan sebagian besar pertanyaan yang diberikan pada sesi tanya jawab dapat terjawab dengan benar. Hal ini menunjukkan bahwa penyuluhan yang diberikan berdampak pada pengetahuan secara signifikan pada siswa-siswi kelas VII SMP YPPK St. Paulus Abepura terkait materi penanggulangan penyalahgunaan obat dan pentingnya konsumsi tablet tambah darah.
Co-Authors Abraham Abraham Adrianz Mario Tethool Ainun Fawaid Andre Anusta Barus Anita Pratiwi Annisa Zahra Amaliah Bakri, Nur F. Boli, Elisabet Bre Chlara Thesalonica Luanmasa Cicilya Bernadth Pasang David W. Rumanasen Dhimas Adhityasmara Dian Advistasari, Yustisia Dimara, Makdalena Irpa Dwi Astuti Elisa, Novi Elisabet Bre Boli Elsye Gunawan Embu, Yohanes Dwi Putra Agung Febby Seru Febby Seru Felycitae Ekalaya Appa Fitra Nur Alam Graciano Aristides Maturbongs Gunawan Pamudji Hasan, Tessa Ayuni Ishak Semuel Beno Ismi Rahmawati Jeanne Giofany Boky John Dominggus Kalor John Dominggus Kalor, John Dominggus Juniarto Mende Karelsius Yewi Krisna Dewi Lorenso Apriyanto Bria Maikel Duwit Muayyidah, Nurita A. S. Muhammad Hisyam Muhammad Hisyam Muhammad Hisyam Murti, Bayu Tri Mustika Endah Pratiwi Novi Elisa Nur Fadilah Bakri Nurhidayah, Annisa Opstaria saptarini Pamudji, Gunawan Putri, Athika Darumas Radian Januari Situmeang Rani Dewi Pratiwi Rosa, Stella Rumanasen, David Waranda Rusnaeni Rusnaeni Sari, Wulan Kartika Sitti Rosnafian Sumardi Sitti Rosnafian Sumardi Sri Selviana Sumardi, Sitti Rosnafian Suprapti, Kevry Tabuni, Frengchy Jalsan Charles Tamara Louraine Jeanette Kainama Tamara Louraine Jeanette Kainama Titi Afelya Valerie Vivian Angelica Faomasi Palege Winda Ade Fitriya B Winda Ade Fitriya B Wulan Kartika Sari Wulan Kartika Sari Yabansabra, Yuliana Ruth Yohana Krisostoma Anduk Mbulang Yohanes Dwi Putra Agung Embu Yuliana Ruth Yabansabra Yustisia Dian Advistasari