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All Journal Sport and Fitness Journal Jurnal Veteriner Indonesia Medicus Veterinus Jurnal Sain Peternakan Indonesia JURNAL PETERNAKAN Damianus Journal of Medicine JITRO (Jurnal Ilmiah dan Teknologi Peternakan Tropis) The Indonesian Biomedical Journal Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Pertanian Agros Jurnal Biotek Jurnal Media Sains Jurnal Sains dan Teknologi Peternakan Jurnal Triton Jurnal Nukleus Peternakan Jurnal Kedokteran Hewan Journal of Urban Health Research Media Penelitian dan Pengembangan Kesehatan Jurnal Sains dan Kesehatan

Ferbian Milas Siswanto

Department Of Chemistry And Biochemistry, School Of Medicine And Health Sciences, Atma Jaya Catholic University Of Indonesia, Jakarta, Indonesia.

Author-ID : 6715508

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary Other

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Bisphenol A Meningkatkan Malondialdehid dan Indeks Apoptosis Hati Tikus (Rattus norvegicus) Jantan Risha Catra Pradhany; I Nyoman Suarsana; I Gusti Ayu Agung Suartini; Ferbian Milas Siswanto
Jurnal Veteriner Vol 23 No 1 (2022)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Bisphenol-A (BPA) merupakan toksikan yang diketahui dampaknya terhadap reproductive toxicities.Namun, beberapa tahun belakangan ini, diketahui pula bahwa BPA menyebabkan stres oksidatif. Stres oksidatif merupakan salah satu faktor penyebab kerusakan organ. Penelitian ini bertujuan untuk membuktikan efek pemberian BPA oral terhadap kadar malondialdehid dan indeks apoptosis pada hati tikus. Penelitian ini menggunakan posttest only control group design. Subjek adalah 14 ekor tikus putih jantan galur Sprague dawley, umur 8-10 minggu, bobot badan berkisar 180 g, dan dalam keadaan sehat. Kelompok kontrol (P0), tujuh ekor tikus, diberikan plasebo berupa 1 mL aquadest selama 21 hari; sedangkan kelompok perlakuan (P1), tujuh ekor tikus, diberikan 400 mg/kgBB tikus BPA selama 21 hari. Hasil menunjukkan bahwa kelompok P1 memiliki kadar MDA hepatik yang lebih tinggi (3,33±0,27 nmol/ mg.prot) dan berbeda nyata (p<0,001) dibandingkan kelompok P0 (2,67±0,14 nmol/mg.prot). Selain itu, kelompok P1 memiliki indeks apoptosis yang lebih tinggi (11,21±2,26%) dan berbeda nyata (p<0,001) dibandingkan kelompok P0 (2,19±0,97%). Berdasarkan hasil tersebut, dapat disimpulkan bahwa pemberian BPA oral meningkatkan malondialdehid dan indeks apoptosis pada hati tikus putih (Rattus norvegicus) jantan.

Prevalensi Penyakit Mastitis pada Ternak Kambing di Kabupaten Majene, Sulawesi Barat Hendro Sukoco; Salmin Salmin; Deka Uli Fahrodi; Nur Saidah Said; Agustina Agustina; Marsudi Marsudi; Ferbian Milas Siswanto; Annisa Putri Cahyani; Ni Putu Vidia Tiara Timur
JURNAL TRITON Vol 13 No 1 (2022): JURNAL TRITON
Publisher : Politeknik Pembangunan Pertanian Manokwari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47687/jt.v13i1.227

Kabupaten Majene menjadi penghasil kambing terbesar di Provinsi Sulawesi Barat. Sistem pemeliharaan kambing yang ada di Kabupaten Majene dilakukan secara tradisional dan semi intensif, karena beternak kambing hanya sebagai usaha sampingan untuk menunjang perekonomian keluarga dan sebagai tabungan. Mastitis adalah salah satu gangguan kesehatan yang sering ditemukan pada ternak kambing. Mastitis merupakan salah satu penyakit yang dapat menyebabkan kerugian ekonomi bagi peternak. Tujuan dari penelitian ini adalah untuk menggambarkan prevalensi penyakit mastitis pada kambing di Kabupaten Majene, Sulawesi Barat. Penelitian ini dilakukan di Kabupaten Majene, Sulawesi Barat pada bulan Mei tahun 2021. Penelitian ini menggunakan metode penelitian kuantitatif dengan pendekatan analisis data sekunder. Data kasus kejadian mastitis pada kambing di Kabupaten Majene, Sulawesi Barat pada tahun 2018-2020 diperoleh dari Dinas Pertanian, Peternakan dan Perkebunan Kabupaten Majene. Analisis data pada penelitian ini menggunakan analisis deskriptif yang bertujuan untuk menggambarkan prevalensi penyakit mastitis pada kambing. Berdasarkan hasil analisis menunjukkan bahwa prevalensi penyakit mastitis pada kambing di Kabupaten Majene mengalami peningkatan dalam rentang waktu dua tahun terakhir. Tingkat prevalensi penyakit mastitis pada tahun 2018 yaitu 0,028%, kemudian pada tahun 2019 terjadi penurunan, menjadi 0,027% dan meningkat pada tahun 2020 menjadi 0,089%. Kecamatan Banggae merupakan satu-satunya wilayah yang mengalami peningkatan jumlah prevalensi mastitis pada kambing dalam 3 tahun terakhir. Sedangkan, di Kecamatan Malunda dan Banggae Timur prevalensi kasus mastitis 0% dari tahun 2018-2020.

PHYLOGENETIC ANALYSIS OF NP AND HN GENE OF NEWLY ISOLATED NDV/Badung-02/AK/14 Ferbian Milas Siswanto; Anak Agung Ayu Mirah Adi
Jurnal Kedokteran Hewan Vol 11, No 2 (2017): June
Publisher : Universitas Syiah Kuala

virus was isolated from suspected Newcastle disease (ND) chicken in backyard farm at Sibang Village, Badung Regency, Bali Province. The isolates were then propagated and confirmed for NDV serologically. RNA isolation was performed by standard Trizol method. Phylogenetic tree analysis of NP gene (nt1020-1561) and HN gene (nt7019-7754) were performed using sequence of Badung-02/AK/14 and selected NDV strains from GenBank. Based on the NP gene sequence, the newly isolate closely related with other NDV strains belong to genotype VII that previously isolated such as Banjarmasin-010/10, Bali-1/07, and Cockatoo/90 with genetic distance 0.2%, 12.6%, and 18.0% respectively. The genetic distance with LaSota/46 virus (genotype II) is 19.6%. Based on HN gene sequence, genetic distance of the Badung-02/AK/14 with other viruses belong to genotype VII such as Banjarmasin-010/10, Bali-1/07, and Cockatoo/90 are 0.4%, 3.7%, and 4.2% respectively. The genetic distance with LaSota/46 virus (genotype II) is 9.0%. There were no difference between the result of nucleotide and amino acid sequence analysis, both in NP and HN gene (P0.05).

LEVEL OF BIOSECURITY APPLICATION IN LAYER CHICKENS FARM IN BANGGAE TIMUR DISTRICT, MAJENE REGENCY Hendro Sukoco; Rustang Rustang; Irma Susanti S; Siti Nuraliah; Suhartina Suhartina; Annisa Putri Cahyani; Suci Andanawari; Dahniar Dahniar; Ferbian Milas Siswanto
Agros Journal of Agriculture Science Vol 25, No 4 (2023): edisi Oktober
Publisher : Fakultas Pertanian, Universitas Janabadra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37159/jpa.v25i4.3476

Biosecurity is something that greatly influences livestock production, especially in reducing the risk and consequences of the introduction of infectious diseases. Therefore, the implementation of biosecurity must be implemented well so that livestock are not easily affected by disease and can produce with good economic efficiency and achieve target production. The aim of this research is to determine the level of biosecurity implementation in layer chickens farms in East Banggae District. This research was carried out in East Banggae District, Majene Regency from August to October 2022 . This type of research uses quantitative descriptive analysis. The sample used in this research was 17 breeders. This research instrument uses a questionnaire whose contents are structured questions/statements, closed answer options using a measurement scale, namely the Guttman scale. The implementation of biosecurity observed in this research is isolation, sanitation and traffic control. Data analysis in this research uses quantitative descriptive analysis. The results of this research show that the application of biosecurity is isolation with a percentage of 75%, sanitation with a percentage of 68.4%, and traffic control with a percentage of 22.2%. Keywords: Biosecurity, East Banggae, Layer Chickens, Majene

PREVALENSI PENYAKIT PINK EYE PADA TERNAK SAPI POTONG DI KABUPATEN MAJENE (Prevalance of pink eye disease in beef cattle in Majene Regency) Hendro Sukoco; Haeryl Nur Asrar; Muhammad Irfan; Ferbian Milas Siswanto
JURNAL NUKLEUS PETERNAKAN Vol 10 No 2 (2023): Desember
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/nukleus.v10i2.12270

Several diseases have been reported to attack beef cattle in Majene Regency, one of which is Pink Eye. In fact, in 2018, 95 cases of Pink Eye disease were found infecting cattle in Majene Regency. This disease does not cause death, but can cause significant economic losses for breeders. This study aims to determine the prevalence of Pink Eye disease in beef cattle in Majene Regency. The location of the research was carried out in Majene Regency and the time of the research was carried out in October 2022. The method used was quantitative descriptive using secondary data. Data was obtained from the Majene Regency Agriculture, Livestock and Plantation Service regarding the number of Pink Eye cases and beef cattle population in 2019-2021. Data were analyzed using quantitative descriptive analysis. Based on research results, it shows that the prevalence of Pink Eye disease in beef cattle in Majene Regency increased in 2019, namely by 0.390% and in 2020 it became 0.996%. However, in 2021 the prevalence of Pink Eye disease will decrease to 0.352%. Tubo Sendana District has a high number of cases of Pink Eye disease every year. It has even become the sub-district with the highest prevalence in 2021 compared to other sub-districts in Majene Regency. Meanwhile, East Banggae and Pamboang Districts have the lowest number of cases and prevalence compared to other Districts in Majene Regency.

Penyakit Mulut dan Kuku (PMK) : Etiologi, Patogenesis, Pencegahan dan Pengendalian Pada Ternak Berkuku Genap atau Belah Sukoco, Hendro; Wahyuni, Sri; Utami, Sri; Cahyani, Annisa Putri; Andanawari, Suci; Siswanto, Ferbian Milas
Jurnal Sain Peternakan Indonesia Vol 18 No 4 (2023)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/jspi.id.18.4.268-273

Foot and Mouth Disease (FMD) was first reported in 1987 in Malang, East Java, caused by imported dairy cattle from the Netherlands. After 36 years of FMD freedom, the disease was re-introduced on 5 May 2022 in East Java. The disease is caused by a virus of the genus Aphthovirus of the Picornaviridae family, which affects even-toed or split-hoofed livestock, both wild and domesticated. Transmission of FMD virus from sick animals to other susceptible animals can occur directly and indirectly. FMD virus can be transmitted rapidly, entering the animal's body directly through the mouth or nose and replicating in epithelial cells in the nasopharyngeal area, then entering the blood (viremia), then multiplying in lymphoglandular glands and epithelial cells in the mouth and footpads resulting in vesicle lesions and blisters. Animals or livestock infected with FMD will show clinical symptoms such as fever up to 41oC, the formation of vesicles or blisters on the mouth, gums, tongue, nipples, and skin around the hooves, hypersalivation, weight loss, and livestock production. Handling and controlling FMD in livestock or animals can be done by isolating and quarantining sick animals, vaccination programs, biosecurity measures in animal husbandry, monitoring livestock traffic, and conducting surveillance.

Epigenetic Alterations in Aging: A Brief Review Ekowati, Ana Lucia; Milas Siswanto, Ferbian
Journal of Urban Health Research Vol. 2 No. 3 (2024): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v2i3.5759

Background: Extensive studies have reported the involvement of epigenetic dynamics in aging. Common epigenetic modifications in aging include the methylation of DNA, rearrangement of chromatin, and regulation of gene expression by non-coding RNA (ncRNA). Some important conclusions that have emerged from various studies in the past few decades are that the lifespan of living organisms is largely determined by epigenetics instead of genetics, where environmental and lifestyle influences that change epigenetic information have a dominant effect. Purpose: This study aims to review current understanding of the mechanisms involved in epigenetic regulation during aging that would provide new insights for the development of strategies to prevent aging. Methods: A search for literature regarding epigenetic regulations in biological aging was carried out in Web of Science and Scopus on “epigenetics” [AND] “aging”. In this study, we used a total of 73 articles published between 2010 and 2024. Results: Aging is accompanied by various alterations in epigenetic marks, including DNA methylation (global hypomethylation in non-CpG regions and hypermethylation OF CpG islands), rearrangement of chromatin (global reduction of histones and redistribution of histone modifications), and ncRNA (particularly miRNA). Epigenetic is a reversible molecular mechanism that allow therapeutic interventions to improve or reverse aging-related pathogenesis. Chemical-based epigenetic manipulation and lifestyle-based epigenetic reprogramming strategies can be developed to improve or reverse aging-related conditions. Conclusion: Based on extensive literature review, we found that epigenetic changes are potential biomarkers for early detection of aging and age-related diseases. Drugs that target key epigenetic signatures are therefore promising to intervene aging. Keywords: aging - age-related disease - biomarker - epigenetic regulation

Prevalensi Penyakit Baliziekte pada Sapi Potong di Kabupaten Majene, Sulawesi Barat Fahrodi, Deka Uli; Said, Nur Saidah; Siswanto, Ferbian Milas; Sukoco, Hendro
Jurnal Ilmu dan Teknologi Peternakan Tropis Vol 9, No 1 (2022): JITRO, January
Publisher : Universitas Halu Oleo

ABSTRAKTujuan dari penelitian ini adalah untuk menggambarkan prevalensi penyakit Baliziekte pada sapi potong di Kabupaten Majene, Sulawesi Barat. Penelitian ini menggunakan metode penelitian kuantitatif dengan pendekatan analisis data sekunder. Data kasus kejadian Baliziekte pada sapi potong di Kabupaten Majene, Sulawesi Barat pada tahun 2018-2020 didapatkan dari Dinas Pertanian, Peternakan dan Perkebunan Kabupaten Majene. Hasil analisis menunjukkan bahwa prevalensi penyakit Baliziekte pada sapi potong di Kabupaten Majene mengalami peningkatan dalam rentang waktu dua tahun terakhir. Jumlah prevalensi penyakit Baliziekte pada tahun 2018 adalah 0,789 %, pada tahun 2019 terjadi penurunan menjadi 0,716 % dan meningkat pada tahun 2020 menjadi 1,257 %. Kecamatan Sendana merupakan satu-satunya daerah dengan peningkatan jumlah kasus Baliziekte pada sapi potong setiap tahunnya, sedangkan Kecamatan Banggae Timur mengalami penurunan jumlah kasus Baliziekte yaitu dari prevalensi 0,078% di tahun 2018 menjadi 0% di tahun 2019 dan 2020. Kecamatan Tubo Sendana merupakan daerah dengan jumlah kasus dan prevalensi tertinggi pada tahun 2020, sedangkan Kecamatan Banggae dan Pamboang merupakan daerah dengan data kasus dan prevalensi 0%. Kata kunci: sapi potong, prevalensi, baliziekte, Kabupaten MajeneThe Prevalence of Baliziekte Disease in Beef Cattle in Majene, West SulawesiABSTRACTThe purpose of this study was to illustrate the prevalence of Baliziekte disease in beef cattle in Majene, West Sulawesi. This study was quantitative research by analyzing the secondary data analysis approach. Data on the Baliziekte incidence in beef cattle in Majene, West Sulawesi in 2018-2020 were obtained from the Department of Agriculture, Livestock and Plantation of Majene Regency. The results of the analysis showed that the prevalence of Baliziekte disease in beef cattle in Majene Regency has increased in the last two years. The prevalence of Baliziekte disease in 2018 was 0.789%, decreased to 0.716% in 2019, and increased sharply to 1.257% in 2020. Sendana District was the only area with an increase in the number of Baliziekte cases in beef cattle every year, while the East Banggae District underwent depletion in the number of Baliziekte cases, from a prevalence of 0.078% in 2018 to 0% in both 2019 and 2020. Tubo Sendana District was the area with the highest number of cases and prevalence in 2020, while the Districts of Banggae and Pamboang were both maintained a 0% case and prevalence throughout the years.Keywords: beef cattle, prevalence, baliziekte, Majene

Desain Primer In Silico Untuk Analisis Expresi Gen Osteopontin (OPN) Sebagai Penanda Kesuburan Pada Kambing Jantan (Capra hircus) Sukoco, Hendro; Suriansyah, Suriansyah; Salmin, Salmin; Cahyani, Annisa Putri; Andanawari , Suci; Akbarrizki , Muzizat; Siswanto, Ferbian Milas
Jurnal Biotek Vol 12 No 2 (2024): DESEMBER
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v12i2.49469

This study aimed to design a pair of primers for analyzing OPN gene expression as a fertility marker in male goats (Capra hircus). The research method employed was an in silico molecular study based on bioinformatics. Nucleotide data were retrieved from the NCBI database using the code NM_001285667.1. The data obtained were processed using Primer-Blast on the NCBI site to identify candidate primers. These candidate primers were subsequently analyzed for secondary structure and primer dimer formation using the Sigma-Aldrich OligoEvaluator.The designed primers were further analyzed for their specifications and sequence similarity with the nucleotide database available on the NCBI site using Primer-Blast and Nucleotide-Blast. The results revealed one pair of primers with ideal criteria: the forward primer 5'-ACCCTCCCGAGTAAGTCCAA-3' and the reverse primer 5'-AGTCCTCCTCTGTGGCATCT-3', capable of amplifying the OPN gene region with a product length of 325 bp. In silico performance tests also demonstrated that the primers could specifically detect the OPN gene in Capra hircus. The primer design for detecting OPN expression is expected to aid in predicting fertility levels in male goats (Capra hircus), thereby enhancing the reproductive efficiency of these livestock.

Article Review: The Role of Blood-sucking Insect Vectors in the Spread of Jembrana Disease in Bali Cattle Sukoco, Hendro; Irfan, Muhammad; Agustina, Agustina; Marsudi, Marsudi; Susanti S, Irma; Cahyani, Annisa Putri; Wahyuni, Sri; Siswanto, Ferbian Milas
Jurnal Peternakan Vol 21, No 2 (2024): September 2024
Publisher : State Islamic University of Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jupet.v21i2.25222

ABSTRACT. Jembrana disease is a contagious disease in cattle and causes enormous economic losses for farmers. This disease, known as bovine lentivirus, was first reported in 1964 in Jembrana District. Jembrana disease specifically attacks Bali cattle at various ages. The cause of this disease is a lentivirus from the Retoviridae family. Jembrana disease transmission occurs by direct contact and is mediated by blood-sucking insect vectors. Not all blood-sucking insects can be vectors for Jembrana disease. Some blood-sucking insects capable of spreading Jembrana disease are Tabanus rubidus flies Culicoides sp mosquitoes, and Aedes lineatopennis, which act as mechanical vectors. As for the Boophilus microplus tick, it is suspected that it acts as a biological vector. Even after re-testing the tick, it could not prove its role as a biological vector for JDV. Prevention and control of this disease can be carried out by vaccination, biosecurity, biosafety, administration of vitamins, isolation of infected livestock, and control of blood-sucking insect vectors by administering insecticides to cages.

Co-Authors A.A. Ayu Putri Permatasari Adrianto, Nicholas Agustina Agustina Akbarrizki , Muzizat Ana Lucia Ekowati Anak Agung Ayu Mirah Adi Andanawari , Suci Andarisuta, Putu Suwarastra Annisa Putri Cahyani Annisa Putri Cahyani Bambang Hadi Kartiko Boedi Prihatini Yenniastoeti Cahyani, Annisa Putri Chela Krisna Denata Dahniar Dahniar Daniel Ardian Soeselo Deka Uli Fahrodi Dewa Ayu Widia Kusuma Ningrat, Dewa Ayu Widia Kusuma Dewi, Ni Putu Eny Sulistya DK, Taufik DWI SURYANTO Erwin Adams Pangkahila Fatqur Rochman Finnegan, Meisy Haeryl Nur Asrar I Dewa Gde Tara Damayanthi, I Dewa Gde Tara I Gede Widhiantara I Gede Widhiantara I Gusti Agung Ayu Suartini I Gusti M. Aman I Gusti Made Aman I Made Kardena I Nyoman Suarsana I Wayan Putu Sutirta Yasa I Wayan Rosiana I Wayan Suryawan Irma Susanti S Irma Susanti S J. A. Pangkahila Linawati Hananta, Linawati Lonah, Lonah Maria Dara Novi Handayani, Maria Dara Novi Marsudi Marsudi Marsudi Marsudi Melita Hidajat Mufassir, Mufassir muhammad irfan Muhammad Irfan Muzizat Akbarrizki, Muzizat Ni Putu Eny Sulistya Dewi Ni Putu Vidia Tiara Timur Novelya , Novelya Nur Hanifah Septiani, Nur Hanifah Nur Saidah Said Pakpahan, Hotmaria Agustina Pamella Haryanto Permatasari, Anak Agung Ayu Putri Putu Dede Yudi Utama, Putu Dede Yudi Risha Catra Pradhany Rita Dewi Rustang Rustang Salmin Salmin Dengo Siti Nuraliah Sri Utami Sri Wahyuni Suci Andanawari Suhartina Suhartina Sukoco, Hendro Suriansyah, Suriansyah Taufan Hendra Wirawan Tri Adi Putra, Tri Adi Wijaya, Ferdian Manuel William William Zita Arieselia Zulfikhar, Rosa

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