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All Journal BALI MEDICAL JOURNAL (BMJ) CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Journal Pharmaceutical Science and Application (JPSA) Jurnal Ergonomi Indonesia (The Indonesian Journal of Ergonomic) Jurnal Veteriner Jurnal e-Biomedik Jurnal Farmasi Klinik Indonesia The Indonesian Biomedical Journal HIGEIA (Journal of Public Health Research and Development) Universa Medicina Jurnal Pendidikan Kesehatan Rekreasi Indonesian of Health Information Management Journal (INOHIM) Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Jurnal Riset Kefarmasian Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Cahaya Mandalika Journal Sport Science, Healt and Tourism of Mandalika (Jontak) Jurnal Kesehatan Saintika Meditory Journal of Global Pharma Technology Jurnal Kesehatan Terpadu Jurnal Farmasi Indonesia Genitri: Jurnal Pengabdian Masyarakat Bidang Kesehatan UNBI Mengabdi Bali International Scientific Forum

I Ketut Tunas

Program Studi Manajemen Informasi Kesehatan, Fakultas Ilmu-ilmu Kesehatan, Universitas Bali Internasional

Author-ID : 715921

Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Uji Validitas dan Reliabilitas Kuesioner EORTC QLQ C-30 untuk Menilai Kualitas Hidup Pasien Kanker Ginekologi di RSUP Sanglah Denpasar Rini Noviyani; I Ketut Tunas; Ayu Indrayathi; Nyoman G. Budiana
Indonesian Journal of Clinical Pharmacy Vol 5, No 2 (2016)
Publisher : Universitas Padjadjaran

Dampak dari penyakit dan pengobatan kanker dapat diukur dengan indikator kualitas hidup menggunakan kuesioner EORTC QLQ C-30. Penelitian cross-sectional dilakukan menggunakan 30 pasien. Data dikumpulkan melalui metode purposive sampling pada pasien yang memenuhi kriteria inklusi, yaitu wanita berusia 30–70 tahun yang didiagnosis kanker ginekologi, pernah menjalani kemoterapi di RSUP Sanglah Denpasar, dan bersedia menandatangani formulir persetujuan pasca penjelasan. Pasien yang tidak dapat berkomunikasi secara rasional menjadi bagian kelompok eksklusi. Validitas dan reliabilitas instrumen diuji menggunakan analisis faktor konfirmatori dengan program STATA® versi 12. Hasil analisis faktor konfirmatori menunjukkan seluruh item pertanyaan memiliki loading factor ( ) > 0,70 sehingga seluruh butir pertanyaan adalah valid. Uji reliabilitas item memberikan nilai >0,50 untuk seluruh item pertanyaan yang menunjukkan seluruh item pertanyaan adalah reliabel. Hasil perhitungan validitas konstrak menghasilkan nilai VE= 0,90 dan reliabilitas konstrak (RF) adalah 1 yang berarti kuesioner EORTC QLQ C-30 memenuhi validitas dan reliabilitas konstrak. Kuesioner EORTC QLQ C-30 sebagai alat ukur kualitas hidup pasien kanker ginekologi di RSUP Sanglah Denpasar adalah valid dan reliabel.Kata kunci: Analisis faktor konfirmatori, kanker ginekologi, kuesioner EORTC QLQ C-30, RSUP Sanglah Denpasar, uji validitas dan reliabilitas Validity and Reliability of EORTC QLQ C-30 Questionnaire in Assessing Quality of Life of Gynecological Cancer Patients in Sanglah Hospital Denpasar The impacts of cancer and its treatment can be measured by indicators of quality of life using the EORTC QLQ C-30 questionnaire. A cross-sectional study was done on 30 patients in Sanglah Hospital Denpasar. Data were collected through purposive sampling of patients who fit the inclusion criteria: women who were 30–70 years old were diagnosed with gynecological cancer, had chemotherapy in Sanglah Hospital, and had agreed to be part of the research by signing the informed consent form. Patients who were unable to rationally communicate became part of the exclusion group in this research. Validity and reliability of the tools in this study were tested using confirmatory factor analysis with STATA ®version 12. Confirmatory factor analysis indicates that all items have a loading factor ( )> 0.70 so that it can be said that all the questions are valid. Reliability items have the value > 0.50 for all questions which shows all questions are reliable. Construct validity of the results of the calculation produce a value VE = 0.90 and the reliability construct (RF) of 1, which meet both validity and reliability constructs. Questionnaire EORTC QLQ C-30 as a measurement of the quality of life of gynecological cancer patients in Sanglah Hospital are valid and reliable.Key words: EORTC QLQ C-30 questionnaire, confirmatory factor analysis, gynecological cancer,Sanglah Hospital Denpasar, the validity and reliability

Evaluasi Nilai Blood Urea Nitrogen dan Serum Kreatinin pada Pemberian Kemoterapi Paklitaksel-Karboplatin pada Pasien Kanker Serviks Sel Skuamosa Stadium IIB-IIIB Rini Noviyani; Ketut Suwiyoga; Anak A. A. W. P. Dewi; Rasmaya Niruri; I. K. Tunas; I N. G. Budiana
Indonesian Journal of Clinical Pharmacy Vol 3, No 2 (2014)
Publisher : Universitas Padjadjaran

Kemoterapi paklitaksel-karboplatin merupakan salah satu terapi untuk kanker serviks. Toksisitas kemoterapi pada ginjal dapat dinilai menggunakan nilai Blood Urea Nitrogen (BUN) dan serum kreatinin. Pada penelitian potong lintang prospektif ini diperoleh 6 pasien kanker serviks yang memenuhi kriteria penelitian. Pemeriksaan kadar BUN dan serum kreatinin dilakukan sebelum kemoterapi pertama dan sesudah kemoterapi seri ketiga. Rentang waktu kemoterapi pertama ke kemoterapi ketiga adalah tiga minggu. Pengambilan sampel penelitian menggunakan consecutive sampling. Data penelitian dianalisis menggunakan paired test dengan interval kepercayaan 95% dengan SPSS 17.0. Hasil evaluasi nilai BUN dan serum kreatinin sebelum dan sesudah kemoterapi menunjukkan tidak terdapat perbedaan yang bermakna antara sebelum kemoterapi pertama dengan sesudah kemoterapi ketiga (p>0,05). Hasil penelitian ini dapat digunakan dokter sebagai pertimbangan untuk memberikan kemoterapi dengan regimen paklitaksel-karboplatin sesuai prosedur yang berlaku karena terbukti tidak menimbulkan penurunan fungsi ginjal pada pasien kanker serviks skuamosa.Kata kunci: BUN, kanker serviks, kemoterapi, paklitaksel-karboplatin, serum kreatininEvaluation of Blood Urea Nitrogen and Serum Creatinine in Squamous Cell Cervical Cancer Patients Stadium IIb-IIIb Who Receiving Paclitaxel- Carboplatin ChemotherapyPaclitaxel-carboplatin chemotherapy is one of cervical cancer therapy. Renal toxicity from chemotherapy can be assessed using the value of Blood Urea Nitrogen (BUN) and serum creatinine. In a prospective cross sectional study was obtained 6 cervical cancer patients who met the research criterias. Examination of BUN and serum creatinine performed before first and after third chemotherapy with the interval time of 3 weeks. Sampling method using consecutive sampling. Data were analyzed using paired test with 95% confidence intervals using the SPSS 17.0. BUN and serum creatinine before and after chemotherapy values obtained p>0.05. BUN and serum creatinine values showed no significant difference between before the first chemotherapy to after third chemotherapy. The doctor may consider using this combination chemotherapy in accordance with the procedures in force due to chemotherapy using paclitaxel- carboplatin shown to be effective and not cause renal toxicity in squamous cervical cancer patients.Key words: BUN, cervical cancer, chemotherapy, paclitaxel-carboplatin, serum creatinine

Evaluasi Nilai Antigen Squamous Cell Carcinoma Pasien Kanker Serviks Sel Skuamosa Stadium II B–III B yang Menerima Kemoterapi Bleomisin, Oncovin®, Mitomisin, dan Cisplatin Rini Noviyani; Ketut Suwiyoga; Intan Puspa; Nyoman Budiana; Ketut Tunas
Indonesian Journal of Clinical Pharmacy Vol 4, No 2 (2015)
Publisher : Universitas Padjadjaran

Kemoterapi Bleomisin, Oncovin®, Mitomisin, dan Cisplatin (BOMP) merupakan salah satu tatalaksana terapi untuk kanker serviks. Penelitian ini bertujuan mengevaluasi respons kemoterapi regimen BOMP pada pasien kanker serviks sel skuamosa stadium IIB–IIIB dengan antigen SCC. Pada penelitian potong lintang prospective ini diperoleh 12 pasien kanker serviks yang memenuhi kriteria inklusi yang diambil dengan metode consecutive sampling. Pemeriksaan kadar antigen SCC dilakukan dengan cara mengambil darah pasien sebelum kemoterapi BOMP seri pertama dan sesudah kemoterapi BOMP seri ketiga kemudian diperiksa dengan alat ARCHITECT SCC assay. Data dianalisis menggunakan paired test dengan interval kepercayaan 95%. Terdapat penurunan rerata nilai antigen SCC pada penderita kanker serviks tipe sel skuamosa setelah tiga seri kemoterapi BOMP meskipun penurunan tersebut tidak bermakna secara statistik (p>0,05). Perbedaan yang tidak bermakna secara statistik ini mungkin disebabkan kurangnya jumlah pasien yang digunakan. Hasil penelitian ini dapat digunakan oleh dokter sebagai pertimbangan untuk melanjutkan kemoterapi BOMP hingga seri keenam sesuai dengan prosedur yang diberlakukan dengan pemantauan rutin terhadap kondisi pasien khususnya nilai antigen SCC untuk untuk memprediksi prognosis dan respons kemoterapi.Kata kunci: Antigen SCC, BOMP, kanker serviks sel skuamosa, kemoterapi, stadium IIB–IIIBEvaluation of Squamous Cell Carcinoma Antigen Value in Stadium IIB–IIIB Squamous Cell Cervical Cancer Patients which Receiving Bleomycin, Oncovin®, Mitomycin, and Cisplatin ChemotherapyBleomycin, Oncovin®, mitomycin, and cisplatin (BOMP) chemotherapy is one of the management of cervical cancer therapy. The aim of this study was to evaluate the response to BOMP chemotherapy regimens in patients squamous cell cervical cancer stage IIB-IIIB using SCC antigen. In this prospective cross sectional study was obtained 12 cervical cancer patients who met the inclusion criteria, which is taken by using consecutive sampling method. Examination of SCC antigen levels was conducted by taking a patient’s blood before the first series and after the third series of BOMP chemotherapy, then further examined by ARCHITECT SCC assay. Data were analyzed using paired test with 95% confidence intervals. Statistical analysis showed that there were a decrease in the average value of SCC antigen in patients with squamous cell cervical cancer types after 3 series of BOMP chemotherapy although this reduction was not statistically significant (p>0.05). The differences are not statistically significant is probably due to insufficient number of patients used in this study. The doctor may consider to continue chemotherapy until the sixth series in accordance with the procedures by routine monitoring of the patient’s condition, especially SCC antigen values for predicting the prognosis and response of chemotherapy.Key words: BOMP, chemotherapy, SCC antigen, squamous cell of cervical cancer, stadium IIB–IIIB

Efek Kemoterapi Bleomisin, Vincristin, Mitomisin dan Karboplatin terhadap Massa Tumor dan Infiltrasi Parametrium pada Pasien Kanker Serviks: Studi Kasus di RSUP Sanglah Denpasar Rini Noviyani; I Nyoman G. Budiana; I Ketut Tunas; Ayu Indrayathi; Rasmaya Niruri; Ketut Suwiyoga
Indonesian Journal of Clinical Pharmacy Vol 6, No 3 (2017)
Publisher : Universitas Padjadjaran

Penggunaan regimen BOM-cisplatin untuk kemoterapi pasien kanker serviks masih belum memberikan hasil efektivitas yang memuaskan, sehingga dilakukan penggantian agen cisplatin dengan karboplatin. Kemoterapi BOM-karboplatin merupakan salah satu regimen terapi kanker serviks di RSUP Sanglah Denpasar. Informasi tentang efektivitas penggunaan BOM-karboplatin untuk kemoterapi kanker serviks masih sangat minim, maka dari itu penelitian ini dilakukan dengan melihat massa tumor dan infiltrasi parametrium. Penelitian ini merupakan penelitian studi kasus terhadap 9 pasien kanker serviks sel skuamosa stadium IIB–IIIB sebelum dan sesudah kemoterapi BOM-karboplatin di RSUP Sanglah dari bulan Februari hingga Agustus 2015 yang memenuhi kriteria. Pemeriksaan Massa Tumor dan Infiltrasi Parametrium (%CFS) dilakukan sebelum kemoterapi seri I dan sesudah kemoterapi seri III. Pengambilan sampel menggunakan consecutive sampling. Data penelitian dianalisis menggunakan uji normalitas yaitu uji Shapiro-Wilk, selanjutnya dianalisis menggunakan uji t berpasangan dengan taraf kepercayaan 95%, sedangkan data berdistribusi tidak normal ditranformasi ke bentuk fungsi logaritma lalu dianalisis dengan uji Wilcoxon. Berdasarkan analisis statistik diketahui bahwa terdapat penurunan bermakna pada massa tumor dan infiltrasi parametrium kiri sesudah 3 seri kemoterapi dengan nilai p<0,05 yaitu masing-masing p=0,001 dan p=0,025, tetapi tidak terdapat penurunan bermakna pada infiltrasi parametrium kanan dengan nilai p>0.05 yaitu p>0,083.Kata kunci: BOM-cisplatin, cancer free space, kanker serviks, RSUP Sanglah Effect of Chemotherapy Bleomycin, Vincristin, Mitomycin and Carboplatin by Tumor Mass and Infiltration Parametrial for Cervical Cancer Patients: Case Study in Sanglah General Hospital, DenpasarBOM-cisplatin regimen for chemotherapy for cervical cancer patients has not resulted high efficacy, hence a replacement of cisplatin with carboplatin is proposed. BOM-carboplatin chemotherapy is at present a treatment for cervical cancer patients in Sanglah Hospital in Denpasar. Information about the efficacy of using the BOM-carboplatin for cervical cancer chemotherapy is not provided, therefore this research performed by observing tumor mass and parametrial infiltration. This research was carried out using case study method on 9 patients with squamous cell cervical cancer stage IIB–IIIB before and after BOM-carboplatin chemotherapy at Sanglah Hospital from February until August 2015. Examination of tumor mass and parametrial infiltration (%CFS) conducted prior to chemotherapy series I and after chemotherapy series III. Sampling was done consecutively. The research data were analyzed using the normal distribution Shapiro-Wilk test continued by paired t-test with 95% confidence level, while data that is classified otherwise is transformed to logarithmic function and were analyzed using the Wilcoxon test. Based on statistical analysis, there is significant reduction in tumor mass and left parametrial infiltration after the third chemotherapy with (p<0.05) which are p=0.001 and p=0.025, but there is no significant reduction of right parametrial infiltration with p>0.05 that is p>0,083.Keywords: BOM-cisplatin, cancer free space, cervix cancer, Sanglah hospital

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN UBI JALAR UNGU (Ipomea batatas L.) TERHADAP PENURUNAN KADAR MALONDIALDEHID (MDA) PADA TIKUS WISTAR YANG MENGKONSUMSI ARAK Ni Putu Widya Astuti; I Putu Darma Wijaya; I Ketut Tunas
CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Vol 5 No 2 (2017)
Publisher : Magister Program of Applied Chemistry, Udayana University, Bali-INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.274 KB)

ABSTRAK: Pengembangan ubi jalar ungu (Ipomea batatas L.)sebagai pangan fungsional banyak dilakukan di Indonesia. Sedangkan pemanfaatan daun ubi jalar ungu belum banyak digunakan dan hanya sebagai limbah hasil pertanian. Telah dilakukan penelitian tentang aktivitas antioksidan dari daun ubi jalar ungu. Daun ubi jalar ungu mempunyai metabolit sekunder yang berfungsi sebagai antioksidan. Salah satu manfaat dari senyawa antioksidan yaitu untuk meredam radikal bebas yang disebabkan oleh stres oksidatif. Stres oksidatif dapat ditimbulkan dari mengkonsumsi minuman beralkohol. Arak merupakan minuman beralkohol khas dari Bali dan digunakan dalam upacara keagamaan. Tujuan penelitian ini yaitu untuk mengetahui pengaruh pemberian ekstrak daun ubi jalar ungu dalam menurunkan kadar MDA pada tikus wistar yang mengkonsumsi arak. Penelitian menggunakan penelitian eksperimental dengan menggunakan rancangan Pre-test Post-tes kontrol Group Desain. Setiap kelompok diberika arak selama 14 hari dan dihari berikutya diberikan ekstrak etanol daun ubi jalar ungu dengan dosis 50 mg/kg BB (P1), 75 mg/kg BB (P2) dan 100 mg/kg BB (P3). Hasil penelitian menunjukkan adanya pengaruh pemberian ekstrak etanol daun ubi jalar ungu pada pemberian 50, 75 dan 100 mg/kg BB ekstrak dengan p < 0,05. ABSTACT: The development of purple sweet potato (Ipomea batatas L.) as a functional food is mostly done in Indonesia. While the utilization of purple sweet potato leaves has not been widely used and only considered as agricultural waste. There has been several research on the antioxidant activity of purple sweet potato leaves. The purple sweet potato leaves have secondary metabolites function as antioxidants. One of the benefits of antioxidant compounds is to reduce free radicals caused by oxidative stress. Oxidative stress can be generated from consuming alcoholic beverages. Arak or palm wine is a typical alcoholic beverage from Bali and commonly used in religious ceremonies. The purpose of this study was to determine the effect of purple sweet potato extracts in reducing levels of MDA in wistar rats that consumed arak. Experimental study was applied in this research using the design of Pre-test Post-control Group Design tests. Each group was given arak for 14 days and the following day the purple sweet potato ethanol extract was given with doses of 50 mg / kg BW (P1), 75 mg / kg BW (P2) and 100 mg / kg BW (P3). The results showed that thre was an effect of ethanol extract of purple sweet potato leaves on the administration of 50, 75 and 100 mg/kg BW extract respectively with p <0,05.

Ethanol Extract of Spondias pinnata Leaves Reduce Parasite Number and Increase Macrophage Phagocytosis Capacity of Mice Infected by Plasmodium berghei Dewa Ayu Agus Sri Laksemi; I Gusti Kamasan Arijana; I Made Sudarmaja; Ni Luh Ariwati; Ketut Tunas; Putu Ayu Asri Damayanti; Ni Luh Putu Eka Diarthini; I Kadek Swastika; Ida Ayu Dewi Wiryantini
The Indonesian Biomedical Journal Vol 13, No 1 (2021)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v13i1.1286

BACKGROUND: Currently, there is no vaccine against malaria in humans, the development of resistance to anti-malarial drugs, causing the need to find new alternatives to overcome malaria infections. This study aimed to determine effect of Spondias pinnata in increasing cellular immunity, especially phagocytosis activity of peritoneal macrophages against Plasmodium berghei infection.METHODS: This was an experimental study with two stages of research, each stage requires 36 Balb/c mice, aged 2 months and weight 20-25 grams. After one week of acclimatization, the mice were put into 6 different groups, each group consisted of 6 mice. The negative control was a group of mice given distilled water for 14 days then infected by P. berghei in the 15th day. Meanwhile, T1, T2, T3, T4 and T5 groups were given S. pinnata leaves ethanol extract with dose of 25, 50, 100, 200 and 400 mg/kg body weight (BW)/day, respectively, and then infected by P. berghei in the 15th day.RESULTS: The results showed that the lowest parasitemia and the highest capacity of macrophage to phagocytose latex was found in treatment group T3 that received 50 mg/kg BW of S. pinnata leaves ethanol extract. Based on analysis of the Pearson correlation test, there was a significant correlation between percent phagocytosis and parasitemia (p<0.05).CONCLUSION: Ethanol extract of S. pinnata leaves lower the parasite number of P. berghei in Balb/c mice and increase the capacity of macrophage to phagocytose latex. However, the mechanisms of how S. pinnata leaves extract in activating phagocytosis capacity and reducing parasitemia still need further investigation.KEYWORDS: phagocytosis, Plasmodium berghei, parasite number, Spondias pinnata

Dampak Pandemi Covid-19 terhadap Tingkat Stres dan Aktivitas Fisik : Telaah Sistematik I Ketut Tunas
Jurnal Pendidikan Kesehatan Rekreasi Vol. 8 No. 2 (2022): Juni 2022
Publisher : Program Studi Pendidikan Jasmani Kesehatan dan Rekreasi FKIP Universitas PGRI Mahadewa Indonesia bekerjasama dengan Asosiasi Prodi Olahraga Perguruan Tinggi PGRI (APOPI)

Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) penyebab penyakit Coronavirus-19 (Covid-19), telah menimbulkan banyak kasus Covid-19 dan kematian di dunia, kondisi ini masih berlangsung dan terjadi pada tahun 2022 di sejumlah negara di dunia. Pandemi Covid-19 telah berdampak terhadap tatanan kehidupan dunia semenjak pertama kali ditetapkan pada awal tahun 2020. Tujuan review adalah untuk mengetahui dampak pandemi Covid-19 terhadap tingkat aktivitas fisik dan tekanan psikologi khususnya tingkat stres. Metode dalam telaah sistematik ini menggunakan pedoman Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Database Medline (Pubmed) digunakan dalam studi ini yang dipublikasikan antara tahun 1 Maret 2020 sampai dengan 10 April 2022 untuk artikel yang terkait dengan pandemi dan dampaknya terhadap aktivitas fisik dan tingkat stres. Pandemi Covid-19 berdampak terhadap perubahan perilaku pola hidup sehat. Terjadi penurunan tingkat aktivitas fisik di sebagian besar penduduk di dunia. Di samping itu, pandemi juga sangat berpengaruh terhadap peningkatan tingkat stress. Terdapat hungaan yang signifikan antara penurunan tingkat aktivitas fisik dengan peningkatan tingkat stress. Pandemi Covid-19 berpengaruh terhadap aktivitas fisik dan tingkat stress. Terjadi penurunan aktivitas fisik dan peningkatan tingkat stress selama pandemi.

PENGARUH KOMBINASI SODIUM LAURIL SULFAT DAN NATRIUM KLORIDA TERHADAP KARAKTERISTIK SAMPO EKSTRAK LIDAH BUAYA Luh Nela Andriani; I Gusti NAWW Putra; I Ketut Tunas
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.304

The shampoo industry in Indonesia is growing. The shampoo formulation contains 2 main ingredients, namely sodium lauryl sulfate (SLS) and sodium chloride (NaCl). One example of natural ingredients in the manufacture of shampoo is Aloe Vera (Aloe vera L.). This study aims to determine the effect of variations in the concentration of SLS and NaCl on the physical and chemical properties of shampoo. This research is an experimental study with 8 formulas. Includes organoleptic test, homogeneity test, viscosity test, foam height test, specific gravity test, and pH test. Making shampoo preparations by weighing all ingredients according to each formulation, leaving the shampoo for 1 day before testing for 4 weeks of storage.The results showed that the organoleptic test and the homogeneity test of NaCl and SLS had no effect on shampoo. In the specific gravity test and the pH test of NaCl and SLS there was no dominant influence on the specific gravity of shampoo. In the foam height test, the SLS coefficient value is higher than NaCl so that SLS dominantly affects the height of the shampoo foam. In the viscosity test the coefficient value of NaCl is higher than SLS so that NaCl dominantly affects the viscosity of the shampoo. The conclusion from this research is that NaCl has a dominant influence on the physical properties, namely viscosity, while SLS has a dominant influence on the physical properties, namely the height of the shampoo foam.

Perbandingan Kelengkapan Resep Konvensional Dengan Resep Berbasis Online Di Apotek X Wilayah Denpasar Selatan Dhiancinantyan Windydaca Brata Putri; Nyoman Titin Brimantari; I Ketut Tunas
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 4, No 1 (2023): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v4i1.10727

One of the pharmaceutical services is to serve the completeness of prescriptions served in health services such as pharmacies. The completeness of prescription services at online-based pharmacies is still carried out by pharmacists but is limited in nature. As a result of incomplete prescription writing, medication errors can occur which are detrimental to the patient (Isro et al., 2018). This study aims to determine the difference in the completeness of conventional recipes with online-based recipes. This study used an analytical observational design, with a cross-sectional study design, and the sampling method was carried out using purposive sampling technique, so that 50 conventional recipes and 50 online recipes were obtained. Based on the results of research conducted at the south Denpasar pharmacy. The results of the study in the form of administrative, pharmaceutical, clinical studies of conventional prescriptions and online prescriptions can be seen in terms of indicators of patient age, doctor's name, No. Doctor's SIP, doctor's initials, R/ sign, dosage form, dosage strength, drug dose, and drug allergy P Value 0.05. Then in terms of indicators of weight px, address px, date of prescription, and drug rules, the value of P Value is 0.05. So, it can be concluded that there is a significant difference between the completeness of conventional prescriptions and online prescriptions in terms of age px, doctor's name, SIP No. , doctor's initial, R/ sign, dosage form, dosage strength, drug dose, and allergy.

A Brief Review of Probiotic: Action Mechanism, Benefits, and Clinical Application on Human Health Dewa Ayu Agus Sri Laksemi; I Ketut Tunas; Ni Luh Putu Eka Diarthini
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Probiotics are live microorganisms that are commonly used as food supplementation to provide a positive impact on human health. There was an increasing number of studies concerned with the benefit of probiotics due to the enhance community awareness of health. The primarily role of probiotics are known strengthening the epithelial barrier, increasing attachment to the intestinal mucosa, inhibiting the attachment of pathogenic bacteria, competitive exclusion of pathogenic microorganisms, producing anti-microbial substances and thereby modulating host immunity by initiating specific genes activation in the host intestinal tract system. The benefits of probiotics are not only limited to the gastrointestinal system but the mechanism of action includes other organs such as respiratory, urogenital, endocrine, and immune system. Hence, this review study will focus mainly on three aspects such as benefits, action mechanism, and its clinical application of probiotics on human health.Keywords: Action mechanism, Benefits, Clinical application, Probiotics.

Co-Authors ., Ni Putu Ayu Laksmini Anak A. A. W. P. Dewi Ayu Laksmini, Putu Budiana, Nyoman Damayanti, Cokorda Istri Dewa Ayu Agus Sri Laksemi Dewa Ayu Agus Sri Laksmi Dewi Puspita Apsari Dewi, Anak A. A. W. P. Dewi, Ni Ketut Cintya I Gusti Kamasan Arijana I Gusti NAWW Putra I Kadek Swastika I Ketut Suwiyoga I Komang Agus Triastawan I Made Sudarmaja I Made Sudarmaja I Nyoman Gede Budiana I Nyoman Mahayasa Adiputra I Nyoman Mahayasa Adiputra I Nyoman Mangku Karmaya I Putu Darma Wijaya I Putu Prisa Jaya . I Putu Riska Ardinata I. Lesmana Ida Ayu Dewi Wiryantini Intan Puspa Kurniastuti, A.A. Ayu Komang Indah Laksmini , Putu Ayu Luh Nela Andriani Luh Putu Ratna Sundari Made Ary Pradnyawati Made Karma Maha Wirajaya Made Sudiari Manuaba, I.A. Ratih Wulansari Mulana, Viktorinus Alfred Saptiono Ni Kadek Weni Diah Gayatri Ni Luh Ariwati Ni Luh Gde Ari Natalia Yudha Ni Luh Putu Eka Diarthini Ni Luh Rustini Ni Luh Rustini Ni Made Linawati Ni Made Sudiari Ni Putu Aryati Suryaningsih Ni Putu Widya Astuti Ni Wayan Mita Arisia Nurwiyanti, . Nyoman Titin Brimantari Nyoman Trisna Aryanata Oktayanti, Leny Prapti Wujani, Ni Luh Gede Puspa, Intan Putri, Dhiancinantyan Windydaca Brata Putu Ayu Asri Damayanti Putu Ayu Asri Damayanti Putu Ayu Indrayathi Putu Ayu Laksmini Putu Ika Farmani Putu Ika Farmani Putu Ika Karma Farmani Putu Indah Budi Apsari R. Niruri Rasmaya Niruri Rasmaya Niruri Rasmaya Niruri Rini Noviyani Sagun Chandra Yowani Sanjaya, I Putu Maheswara Dharma Septiari, I Gusti Ayu Agung Sri Laksemi, Dewa Ayu Agus Suadnyana, Ida Ayu Astiti Teri, Komang Victorinus Alfred Saptiono Mulana Viktorinus Alfred Saptiono mulana Viktorinus Alfred Saptiono Mulana Viktorinus Alfred Saptiono Mulana Vitalia Fina Carla Rettobjaan Widowati, I Gusti Ayu Rai - Widyani, Ni Made Wimpie I Pangkahila Wintariani, Ni Putu Wirajaya, Karma Maha Yudha, A.A. Ngurah Bagus Arista Yuniantari, Ni Wayan

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