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All Journal MANAJEMEN HUTAN TROPIKA Journal of Tropical Forest Management Jurnal Ilmu Dasar Indonesian Journal of Cancer Chemoprevention AGRIVITA, Journal of Agricultural Science Indonesian Journal of Biotechnology Bioeksperimen: Jurnal Penelitian Biologi Pharmacon Majalah Obat Tradisional Journal of Tropical Biodiversity and Biotechnology The Indonesian Biomedical Journal Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal Biologi Tropis Communications in Science and Technology JSFK (Jurnal Sains Farmasi & Klinis) Menara Perkebunan Proceeding Biology Education Conference Berkala Ilmiah Biologi
Tri Rini Nuringtyas
Department Of Biology, Faculty Of Biology, Universitas Gadjah Mada, Jl. Bulaksumur, Sleman, DI Yogyakarta, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health Veterinary

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Journal : Proceeding Biology Education Conference

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Identifikasi Senyawa Curcumin, Bisdemethoxycurcumin dan Demethoxycurcumin Rimpang Curcuma xanthorrhiza Roxb. dan Curcuma longa L. dengan 1H NMR Erwin Nur Indiarto; Tri Rini Nuringtyas; Yekti Asih Purwestri; Respati Tri Swasono; Yosi Bayu Murti
Proceeding Biology Education Conference: Biology, Science, Enviromental, and Learning Vol 15, No 1 (2018): Proceeding Biology Education Conference
Publisher : Universitas Sebelas Maret

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Abstract

Curcumin and its derivates (Bisdemethoxycurcumin, Demethoxycurcumin) are natural dyes found in Curcuma xanthorrhiza dan Curcuma longa. Parmacologic evidence suggests all three are antioxidant, antiinflamatory, and anticancer. The objective of this research was to identify and measure the intensity of Curcumin compounds, Bisdemethoxycurcumin, and Demethoxycurcumin rhizome C. xanthorrhiza and C. longa by using 1H NMR spectra. Rhizome C.xanthorrhiza and C. longa collected from Wonogiri, Central Java. The rhizomes were dried in the oven at 40 °C and were powdered using a blender. The dried powder sample was extracted using methanol-d4  containing 0.01% TMSP and followed by ultrasonication for 15 minutes. The supernatant was separated from the solution by 10.000 rpm centrifugation for 10 minutes. The supernatant was transferred to NMR tube and analysed by using JEOL 500 MHz NMR. The obtained data were analysed by Mnova 12 software and Simca 14. Results of comparsion of 1H NMR spectra of both rhizomes with reference were identified Curcumin, Bisdemethoxycurcumin, Demethoxycurcumin compounds. The highest intensity all of three compound was found in Curcuma longa and with One way Anova test result obtained p<0,05. The two rhizomes show a good separation on the OPLS-DA scoreplot with Q2 82,1% indicating a good model. The study showed that Curcumin, Bisdemethoxycurcumin, Demethoxycurcumin compounds were found in both rhizomes and had different intensity
Co-Authors Adita Yuniati Puspitasari Afifah, Laelatul Aldawood, Abdulrahman Saad ALIM ISNANSETYO Amalia, Alifa Andi Nur Cahyo Andyra, Vania Uly Aries Bagus Sasongko BUDI SETIADI DARYONO Caroline Dwiseptianti Chandra, Klara Kharisma Bunga Charlie Ester de Fretes Damayanti, Frisca Dedi Setiadi Denis FABRE Dewi, Siska Noviana DIAH RACHMAWATI Diani Mentari Dio N. Wijaya Donny Widianto Dwi Indriani Manurung Dwiseptianti, Caroline Dyah Ismoyowati, Dyah Eka Tarwaca Susila Putra Eka Tarwaca Susila Putra Eko Pujiono Endar Marraskuranto Enik Nurlaili Afifah Erwin Nur Indiarto Fajri Marisa Febri Adi Susanto Febri Adi Susanto Hari Purwanto Harno Dwi Pranowo Hendry Tri Sakti Saragih Hiqmah Yusi Yana ILG Nurtjahjaningsih, ILG JAKA WIDADA Krisnanda Surya Dharma Krisnanda Surya Dharma L. Hartanto Nugroho Lailaty, Intani Quarta Liliana Baskorowati Lindia Anggraini Lindia Anggraini Lisna Hidayati Marlyn Dian Laksitorini, Marlyn Dian Mashudi Mashudi Megayani Sri Rahayu Mirtani Naima Muhammad Imam Surya Muhammad Nursid Mustafid Rasyiid Naima, Mirtani Nastiti Wijayanti Nastiti Wijayanti Nastiti Wijayanti Nastiti Wijayanti Nastiti, Anisa Diana Novitasari, Laras Nugroho, Hartanto Nurrahmi Dewi Fajarningsih, Nurrahmi Dewi Pascal MONTORO Purnomo Purnomo Qulbi, Siti Shofa Assyifa Rahma Nurdiyanti Rahma Nurdiyanti Rahmawati, Rahmawati Ramadhani, Fathur Syahrian Rendi Mahadi Rendi Mahadi Respati Tri Swasono Rina Laksmi Hendrati Rina Sri Kasiamdari Riris Istighfari Jenie Riska Wulansari Roberdi, Roberdi Rohman, Randi Abdur Ronny Martien Rudi Hari Murti Rudi Hari Murti Sebastian, Alfino Setiowati, Retno Diah Sigit Dwi Maryanto Sri Wening Sudarsono Sugeng Pudjiono, Sugeng SUKIRNO Sumardi . Surta, Muhammad Imam Susanto, Febri Adi Tony Liwang Tri Joko Raharjo Tri Joko Raharjo Tri Wibawa Triyaningsih Triyaningsih, Triyaningsih Utomo, Condro Wibisono, Mochamat Gunawan Wulansari, Riska Yekti Asih Purwestri Yosi Bayu Murti Zulkifli Zulkifli