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Intan Adevia Rosnarita
Universitas Muhammadiyah Kudus
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Efektivitas Penggunaan Ringer Laktat Vs Ringer Asetat terhadap Durasi Rawat Inap Pasien Demam Berdarah Dengue Erwin Ari Pratiwi; Eko Retnowati; Intan Adevia Rosnarita
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 1 (2025): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i1.7462

Abstract

Dengue hemorrhagic fever (DHF) is an endemic disease with high prevalence in Indonesia, particularly during the rainy season, when incidence rates significantly increase. One of the main treatments is supportive therapy through intravenous fluid administration to prevent shock and aid recovery. Ringer’s lactate and Ringer’s acetate are commonly used crystalloid fluids that differ in electrolyte composition and metabolic pathways in the body. This study aimed to compare the effectiveness of Ringer’s lactate and Ringer’s acetate in relation to the length of hospital stay among DHF patients. This research employed a retrospective analytic observational design, using data from medical records of 154 inpatients at RSUD dr. R. Soetrasno Rembang in 2024. Data analysis included normality testing and independent t-tests. The average length of hospitalization in the Ringer’s lactate group was 4.35 ± 1.121 days, while in the Ringer’s acetate group it was 4.06 ± 1.185 days. Although there was a difference in mean values, statistical analysis showed no significant difference between the two groups (p = 0.131). No significant differences were also found in laboratory parameters (platelets, leukocytes, hemoglobin, hematocrit) or body temperature. Based on these findings, it can be concluded that both types of fluids are equally effective as supportive therapy for DHF patients. Fluid selection may be adjusted according to the patient’s clinical condition, availability, and cost considerations.
PERBANDINGAN EFEKTIVITAS CEFOTAXIME DAN CEFTRIAXONE PADA PASIEN RAWAT INAP PEDIATRI DENGAN PNEUMONIA Intan Adevia Rosnarita; Akhtyasin Akhyasin; Sintia Kusuma Dewi
IJF (Indonesia Jurnal Farmasi) Vol 9, No 1 (2024): IJF (Indonesia Jurnal Farmasi)
Publisher : Universitas Muhammadiyah Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26751/ijf.v9i1.2425

Abstract

The prevalence of pneumonia for pediatrics in Indonesia is quite high. This condition is a concern for clinicians, especially pharmacists in handling the treatment of pneumonia in pediatrics. Treatment of pneumonia for pediatrics needs antibiotic therapy such as cefotaxime and ceftriaxone. This study aims to compare the effectiveness of the use of antibiotics cefotaxime and ceftriaxone in pediatric pneumonia patients at the inpatient installation of RSI Sunan Kudus Period February-April 2021. This study is a non-experimental research study with an observational analytic character, with purposive sampling, statistical analysis was carried out To compare the effectiveness of using cefotaxime and ceftriaxone based on duration of use and clinical symptoms, SPSS was performed using Paired T-Test. Based on the average duration of use for antibiotics cefotaxime 5 days and ceftriaxone 4.41 days. There was no difference in the average use of cefotaxime and ceftriaxone based on clinical symptoms such as cough, retractions, fever, shortness of breath and sore throat. The results of statistical analysis showed that ceftriaxone was more effective than cefotaxime in pediatric pneumonia, while there was no significant difference between ceftriaxone and cefotaxime (α) 0.05. The use of ceftriaxone is more effective in treating pediatric pneumonia than cefotaxime.
Co-Authors Ade Kurnia Bayu Firdaus Adzkia Fitri Ahmad Suriyadi Muslim Akhtyasin Akhyasin AMALIA, SHOFIA Anny Rosiana Masithoh Apriliasari, Fiona Astuti, Amy Arbaatun Nisa Besan, Emma Jayanti Besan, Ulfa Nabila Bintari Tri Sukoharjanti Eko Retnowati Eko Retnowati Emma Jayanti Besan Endang Setyowati Erwin Ari Pratiwi Etikasari, Ria Fahrudin Arif Fairus, Mustika Farni Yuliana Pratiwi Farni Yuliana Pratiwi Fina Aulia Maharani Galih Kurniawan Hadiatussalamah Hadiatussalamah Hasriyani Irvan Shahrul Hidayat Jauharotul Firdausiyah Kinanti Putri Amalia Muadzah Muadzah Muhamad Khudzaifi Muhammad Nurul Fadel Nafisa Zaharani Hidayanti Nanang Munif Yasin Novia Ariani Dewi Priswa, Nindya Ramadhani Annisa Rahim Rengganis, Mutiara Ria Etikasari Riana Putri Rahmawati Ridwanto, Muhammad Sintia Kusuma Dewi Siti Mumfaridatul Mukarromah Wulandari Pramuda Wardani Yahya Adi Alfatih Yuda Anzas Mara Yuda Anzas Mara Yuliasari, Aulia Wahyu Zaenal Fanani Zaimatuddunia, Irma