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All Journal Journal of Applied Geospatial Information JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) 2-TRIK: TUNAS-TUNAS RISET KESEHATAN BENING Open Access Indonesian Journal of Medical Reviews Global Health Science (GHS) Journal Of Human And Education (JAHE) Formosa Journal of Science and Technology (FJST) Generics: Journal of Research in Pharmacy JOMPA ABDI: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Bhinneka Perigel: Jurnal Penyuluhan Masyarakat Indonesia Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Indonesian Journal of Advanced Research (IJAR) Jurnal Kesehatan Farmasi Jurnal Pengabdian Masyarakat Bangsa Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran JUKEJ: Jurnal Kesehatan Jompa Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan PEDAMAS (Pengabdian Kepada Masyarakat) Jurnal Pendekar Nusantara Natural: Jurnal Pelaksanaan Pengabdian Bergerak Bersama Masyarakat Generics : Journal of Research in Pharmacy Bhakti Sabha Nusantara Journal of Health Research and Technology Karya Kesehatan Journal of Community Engagement International Journal Of Health And Social Behavior International Journal of Health and Medicine Masyarakat: Jurnal Pengabdian Media Pengabdian Kesehatan Indonesia Jurnal Kesehatan Lentera Aisyiyah Jurnal Riset dan Pengabdian Interdisipliner Jurnal Pengabdian Ilmu Kesehatan
Fifin Oktaviani
Pharmacy Study Program, Faculty Of Health Sciences, Universitas Batam, Batam, Indonesia
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Rasionalitas Penggunaan Obat Antihipertensi pada Pasien Rawat Jalan di Rumah Sakit X Kepulauan Riau Tahun 2024 Fifin Oktaviani; Aldhehita Ari Kusumawati; Nasya Efrilianda Putri
Generics: Journal of Research in Pharmacy Vol 6, No 2 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i2.32498

Abstract

Hipertensi merupakan penyakit kardiovaskular kronis yang menjadi kontributor utama morbiditas dan mortalitas global. Penggunaan obat antihipertensi yang tidak rasional berpotensi menurunkan efektivitas terapi dan memperburuk luaran klinis pasien. Penelitian ini bertujuan mendeskripsikan pola penggunaan antihipertensi dan mengevaluasi rasionalitasnya pada pasien rawat jalan di rumah sakit X Kepulauan Riau berdasarkan empat kriteria: tepat indikasi, tepat pasien, tepat obat, dan tepat dosis. Studi observasional non-eksperimental dengan desain retrospektif dilaksanakan pada periode Juli-September 2024. Sebanyak 220 rekam medis dipilih melalui systematic random sampling dan dievaluasi menggunakan JNC 8, AHA/ACC 2017, ISH 2020, dan Pharmacotherapy Handbook DiPiro edisi ke-10. Hasil menunjukkan regimen dominan adalah kombinasi dua obat Amlodipin–Candesartan (24,55%), diikuti kombinasi tiga obat Amlodipin-Candesartan-Bisoprolol (16,36%). Evaluasi rasionalitas memperoleh tepat indikasi 100%, tepat pasien 97,50%, tepat obat 78,64%, dan tepat dosis 99,09%. Temuan ini menegaskan perlunya audit farmakoterapi berkelanjutan dan penguatan kolaborasi klinisi apoteker untuk mengoptimalkan terapi antihipertensi.
Edukasi Pembuatan Jamu Herbal untuk Peningkatan Kesehatan Keluarga di Belakang Padang, Batam Fifin Oktaviani; Hilda Muliana; Heldi Candra; Nisa Andryani Nadapdap
Media Pengabdian Kesehatan Indonesia Vol. 3 No. 2 (2026): JULY
Publisher : Kabar Gizi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62358/mv1vma58

Abstract

Pergeseran gaya hidup modern yang ditandai dengan pola makan tidak sehat dan tingkat stres yang tinggi meningkatkan risiko penyakit degeneratif serta menurunkan daya tahan tubuh. Jamu tradisional merupakan warisan budaya Indonesia yang secara ilmiah terbukti mengandung senyawa bioaktif bermanfaat bagi kesehatan. Ibu-ibu rumah tangga di Kelurahan Belakang Padang, Kota Batam, masih memiliki pengetahuan terbatas dalam mengolah rimpang menjadi jamu yang higienis dan berkualitas. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan dan keterampilan ibu rumah tangga dalam membuat jamu kesehatan berbahan dasar serai, temulawak, kunyit, jahe, dengan pemanis gula merah. Metode yang digunakan adalah penyuluhan, demonstrasi, dan praktik langsung, disertai evaluasi melalui pre-test dan post-test. Kegiatan dihadiri oleh 45 orang ibu rumah tangga pada tanggal 31 Mei 2025. Hasil menunjukkan adanya peningkatan signifikan pengetahuan peserta dari rata-rata 58% menjadi 89% setelah kegiatan, serta kemampuan peserta dalam membuat jamu secara mandiri. Kegiatan ini diharapkan menjadi dasar pengembangan industri rumah tangga berbasis keluarga dan peningkatan derajat kesehatan masyarakat.
Rasionalitas Penggunaan Obat Antihipertensi pada Pasien Rawat Jalan di Rumah Sakit X Kepulauan Riau Tahun 2024 Fifin Oktaviani; Aldhehita Ari Kusumawati; Nasya Efrilianda Putri
Generics: Journal of Research in Pharmacy Vol 6, No 2 (2026): Generics : Journal of Research in Pharmacy
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v6i2.32498

Abstract

Hipertensi merupakan penyakit kardiovaskular kronis yang menjadi kontributor utama morbiditas dan mortalitas global. Penggunaan obat antihipertensi yang tidak rasional berpotensi menurunkan efektivitas terapi dan memperburuk luaran klinis pasien. Penelitian ini bertujuan mendeskripsikan pola penggunaan antihipertensi dan mengevaluasi rasionalitasnya pada pasien rawat jalan di rumah sakit X Kepulauan Riau berdasarkan empat kriteria: tepat indikasi, tepat pasien, tepat obat, dan tepat dosis. Studi observasional non-eksperimental dengan desain retrospektif dilaksanakan pada periode Juli-September 2024. Sebanyak 220 rekam medis dipilih melalui systematic random sampling dan dievaluasi menggunakan JNC 8, AHA/ACC 2017, ISH 2020, dan Pharmacotherapy Handbook DiPiro edisi ke-10. Hasil menunjukkan regimen dominan adalah kombinasi dua obat Amlodipin–Candesartan (24,55%), diikuti kombinasi tiga obat Amlodipin-Candesartan-Bisoprolol (16,36%). Evaluasi rasionalitas memperoleh tepat indikasi 100%, tepat pasien 97,50%, tepat obat 78,64%, dan tepat dosis 99,09%. Temuan ini menegaskan perlunya audit farmakoterapi berkelanjutan dan penguatan kolaborasi klinisi apoteker untuk mengoptimalkan terapi antihipertensi.
Comparative Effectiveness and Safety of Lemborexant Versus Benzodiazepines in Patients with Insomnia: A Systematic Review and Meta-Analysis Kartini Hasballah; Fifin Oktaviani; Heldi Candra; Wilda Fasim Hasibuan
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6976

Abstract

Chronic insomnia is a common sleep disorder that erodes quality of life, cognitive performance, and day-to-day safety. Benzodiazepines remain a mainstay of pharmacological treatment, yet their safety profile is a persistent concern, especially among older adults. Lemborexant, a newer dual orexin receptor antagonist, offers a distinct mechanism and a claim of improved safety. This review set out to weigh the two agents against each other on effectiveness and safety, focusing on daytime somnolence, fall risk, and cognitive impairment. A systematic review and meta-analysis was performed in line with the PRISMA 2020 guideline. Five databases (PubMed/MEDLINE, Scopus, EMBASE, the Cochrane Library, and ScienceDirect) were searched up to April 2026. Randomised controlled trials and comparative observational studies contrasting lemborexant with benzodiazepines or placebo in adults with insomnia were eligible. Risk of bias was appraised with the Cochrane RoB 2.0 tool and the Newcastle-Ottawa Scale. From 747 records, 18 studies entered the qualitative synthesis and 12 the quantitative analysis (n = 49,907 participants). Compared with benzodiazepines, lemborexant produced less daytime somnolence (SMD = -0.34; 95% CI: -0.52 to -0.16; p < 0.001), a lower risk of falls (log OR = -0.51; 95% CI: -0.72 to -0.30; p < 0.001), and less cognitive impairment (SMD = -0.18; 95% CI: -0.34 to -0.02; p = 0.028). Between-study heterogeneity was moderate (I² = 38-51%). Lemborexant shows a more favourable safety profile than benzodiazepines for daytime somnolence, falls, and cognition, particularly in older adults. The findings support considering lemborexant as a first-line pharmacological option for chronic insomnia when non-pharmacological therapy is unavailable or inadequate.
Association of Polypharmacy and Drug-Related Problems with Quality of Life in Hypertensive Patients with Comorbidities Kartini Hasballah; Zaki Mubarak; Heldi Candra; Fifin Oktaviani
Jurnal Ventilator Vol. 3 No. 2 (2025): Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v3i2.2811

Abstract

Hypertension frequently coexists with comorbidities such as type 2 diabetes, dyslipidaemia, and chronic kidney disease. That mix produces polypharmacy and raises the risk of drug-related problems (DRPs), which in turn can erode quality of life (QoL). This study set out to examine the relationship between polypharmacy, DRPs, and QoL in hypertensive patients with comorbidities. An observational cross-sectional study was carried out at the outpatient internal medicine clinic of X Hospital, Batam, from January to June 2024. Consecutive sampling yielded 130 patients meeting the inclusion criteria. Polypharmacy was defined as the concurrent use of five or more medications. DRPs were classified with the Pharmaceutical Care Network Europe (PCNE) V9.1 tool, Bahasa Indonesia version. QoL was measured using the validated Indonesian SF-36 questionnaire. Data were analysed with Spearman rank correlation and multivariate logistic regression. Polypharmacy was present in 63.1% of patients, and DRPs were identified in 76.2%, most commonly drug interactions (31.4%) and dose-selection issues (24.8%). Polypharmacy correlated negatively with total QoL scores (r = -0.542; p < 0.001), as did DRPs (r = -0.418; p < 0.001). Multivariate analysis confirmed polypharmacy (AOR 3.24; 95% CI 1.62-6.48) and DRPs (AOR 2.87; 95% CI 1.41-5.85) as independent predictors of poor QoL. Integrated pharmaceutical care with an explicit focus on medication review is critical for mitigating DRPs and improving QoL in this population.
Evaluation of the Rationality of Antibiotic Use in Acute Respiratory Infection Patients at Hospital X, Batam City Zaki Mubarak; Fifin Oktaviani; Hidayati Hidayati; Aldhehita Ari Kusumawati
Jurnal Anestesi Vol. 4 No. 1 (2026): Januari : Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v4i1.2810

Abstract

Acute respiratory infection (ARI) is among the conditions with the highest antibiotic prescribing rates in health care, even though most cases are of viral origin and self-limiting. Irrational prescribing in this setting is a major driver of antimicrobial resistance. This study aimed to evaluate the rationality of antibiotic use in ARI patients at Hospital X, Batam City. A cross-sectional design was applied, with data collected retrospectively from the medical records of ARI patients who received antibiotics during January-March 2024. Rationality was assessed qualitatively using the Gyssens method, while antibiotic selection was mapped against the WHO 2023 AWaRe classification. Of 96 prescriptions meeting the inclusion criteria, the most frequent antibiotics were amoxicillin (31.3%) and amoxicillin-clavulanic acid (22.9%), with acute pharyngitis (27.1%) as the leading diagnosis. Based on the AWaRe classification, the Access group predominated (68.8%), exceeding the WHO target of 60% or higher. Gyssens evaluation showed that 60.4% of prescriptions were rational (category 0), whereas 39.6% were irrational, with the most common deviations being inappropriate dosing (category IIA; 9.4%), availability of a more effective antibiotic (category IVA; 6.3%), and overly short duration (category IIIB; 5.2%). These findings indicate that although antibiotic selection was relatively appropriate, dosing and duration still require improvement. Strengthening the antimicrobial stewardship programme with emphasis on dose and duration accuracy is recommended to improve treatment quality while curbing resistance in health facilities.
EVALUASI PRAKTIK DISPENSING ANTIBIOTIK PADA PERMINTAAN TANPA RESEP DI APOTEK KOMUNITAS MENGGUNAKAN METODE SIMULATED PATIENT Aldhehita Ari Kusumawati; FIFIN OKTAVIANI; Lita Riastienanda Putri
Jurnal Kesehatan Lentera 'Aisyiyah Vol. 9 No. 1 (2026): Jurnal Kesehatan Lentera 'Aisyiyah
Publisher : BPPM Politeknik 'Aisyiyah Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58170/jkla.v9i1.281

Abstract

Penjualan antibiotik tanpa resep dokter merupakan salah satu faktor utama yang berkontribusi terhadap meningkatnya resistensi antimikroba, terutama di negara berpendapatan rendah dan menengah, termasuk Indonesia. Penelitian ini bertujuan untuk mendeskripsikan proporsi, pola, dan kelengkapan praktik penyerahan antibiotik tanpa resep dokter di apotek komunitas Kota Batam serta mengidentifikasi faktor-faktor yang mendorong praktik tersebut berdasarkan perspektif tenaga kefarmasian. Studi observasional dengan desain potong lintang (cross-sectional) dilakukan pada Maret–Mei 2026 menggunakan metode simulated patient di 74 apotek komunitas berizin yang dipilih melalui systematic random sampling. Skenario yang digunakan berupa permintaan langsung amoksisilin untuk keluhan infeksi saluran pernapasan akut. Data dianalisis secara deskriptif, sedangkan hubungan antarvariabel diuji menggunakan uji chi-square. Dari 74 apotek yang dikunjungi, 33 apotek (44,6%) menyerahkan antibiotik tanpa resep dokter. Amoksisilin kapsul merupakan antibiotik yang paling sering didispensasikan, diikuti oleh sefadroksil kapsul dan sirup, sefiksim 100 mg kapsul, siprofloksasin 500 mg tablet, serta azitromisin 500 mg tablet. Konseling mengenai aturan pakai diberikan pada 81,8% kasus, namun informasi mengenai durasi pengobatan lengkap (27,3%), efek samping (12,1%), dan risiko resistensi antimikroba (6,1%) masih sangat jarang disampaikan. Berdasarkan perspektif tenaga kefarmasian, faktor utama yang mendorong praktik tersebut meliputi permintaan pasien yang persisten, persaingan antar apotek, target finansial pemilik apotek, serta lemahnya penegakan regulasi. Penyerahan antibiotik tanpa resep dokter masih menjadi praktik yang umum di apotek komunitas Kota Batam dan disertai dengan kualitas konseling yang belum memadai.
DAMPAK IMPLEMENTASI SIMRS TERHADAP WAKTU TUNGGU DAN KEPUASAN PASIEN PADA PELAYANAN RESEP RACIKAN DAN NON-RACIKAN DI RS X KEPULAUAN RIAU Lita Riastienanda Putri; FIFIN OKTAVIANI; Hidayati
Jurnal Kesehatan Lentera 'Aisyiyah Vol. 9 No. 1 (2026): Jurnal Kesehatan Lentera 'Aisyiyah
Publisher : BPPM Politeknik 'Aisyiyah Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58170/jkla.v9i1.282

Abstract

Waktu tunggu dan kepuasan pasien merupakan indikator mutu utama pelayanan kefarmasian rumah sakit, khususnya pada resep racikan dan non-racikan. Integrasi Sistem Informasi Manajemen Rumah Sakit (SIMRS) diharapkan dapat mempersingkat waktu tunggu dan meningkatkan kepuasan pasien. Tujuan penelitian untuk menganalisis dampak implementasi SIMRS terhadap waktu tunggu pelayanan resep dan kepuasan pasien di Instalasi Farmasi Rawat Jalan RS X Kepulauan Riau. Metode penelitian ini menggunakan desain kuasi-eksperimental dengan rancangan before-after non-ekuivalen melibatkan 140 resep rawat jalan (100 non-racikan, 40 racikan) yang dibagi menjadi kelompok sebelum dan sesudah implementasi SIMRS. Waktu tunggu diukur sejak resep diserahkan hingga obat diterima pasien, sedangkan kepuasan pasien dinilai menggunakan kuesioner SERVQUAL tervalidasi pada lima dimensi. Data dianalisis menggunakan uji t independen/Mann-Whitney U dan uji Chi-square (α=0,05). Hasil penelitian rerata waktu tunggu resep non-racikan menurun dari 42,5±12,3 menjadi 24,8±8,1 menit, dan resep racikan dari 68,4±15,6 menjadi 41,2±11,4 menit setelah implementasi SIMRS (p<0,001). Skor kepuasan SERVQUAL keseluruhan meningkat dari 3,09 menjadi 4,13 (p<0,001), dengan peningkatan tertinggi pada dimensi daya tanggap. Implementasi SIMRS secara signifikan menurunkan waktu tunggu pelayanan resep dan meningkatkan kepuasan pasien, baik pada pelayanan resep racikan maupun non-racikan. transletkan ke bahasa inggris dengan grammar yang baik
Implementasi Edukasi DAGUSIBU dalam Meningkatkan Literasi Penggunaan Antibiotik pada Kasus Infeksi Gigi dan Mulut di Masyarakat Kartini Hasballah; Zaki Mubarak; Fifin Oktaviani; Aldhehita Ari Kusumawati; Hidayati Hidayati
Jurnal Pengabdian Ilmu Kesehatan Vol. 5 No. 2 (2025): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v5i2.7891

Abstract

Dental and oral infections are among the most common health complaints in the community and are frequently self-treated with antibiotics without a physician's prescription. Inappropriate antibiotic use is one of the main drivers of antimicrobial resistance (AMR), which currently poses a global health threat. This community service activity aimed to improve public literacy regarding the rational use of antibiotics in dental and oral infection cases through a DAGUSIBU (Get, Use, Store, Dispose) educational approach. The activity was carried out in June 2025 in Belakang Padang Subdistrict, Batam City, Riau Islands Province, involving 42 participants. A pre-experimental one-group pretest-posttest method was applied, comprising preparation, implementation (pretest, interactive lecture supported by leaflets and slides, demonstration, and discussion), and evaluation. A validated and reliable knowledge questionnaire was used as the instrument, and data were analyzed using the Wilcoxon test. The results showed an increase in the mean knowledge score from 58.7 (poor category) to 85.3 (good category), with the proportion of participants in the good category rising from 19.0% to 83.3%. The Wilcoxon test yielded p = 0.000 (p < 0.05), indicating a significant difference before and after the education. DAGUSIBU education was proven effective in improving antibiotic-use literacy in dental and oral infection cases and can serve as a community-based strategy to control antibiotic resistance.
Penggunaan Obat yang Aman pada Anak melalui Pendekatan Interprofesional Zaki Mubarak; Kartini Hasballah; Fifin Oktaviani; Hidayati Hidayati; Aldhehita Ari Kusumawati
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 3 No. 1 (2025): February: Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v3i1.2550

Abstract

Medication errors among children in household settings remain a leading cause of preventable harm, particularly in small island areas with limited access to healthcare professionals such as Kasu Island, Belakang Padang District, Batam City. This community service program aimed to improve the knowledge and skills of parents, integrated health post (posyandu) cadres, and early childhood teachers regarding safe medication use in children through an interprofessional approach involving pharmacists, physicians, nurses, and midwives. The activity was conducted on February 2, 2025, through field visits by an interprofessional team to posyandu cadres, using interactive lectures based on the DAGUSIBU principles, demonstrations of liquid dosage measurement, case simulations of fever and diarrhea in children, and interprofessionally facilitated focus group discussions. Evaluation employed a one-group pretest–posttest design involving 42 participants. The results showed a significant increase in the mean knowledge score from 50.4 ± 10.9 to 83.5 ± 7.8 (p<0.001; Wilcoxon test), with the greatest improvement in medicine disposal and prudent antibiotic use. The interprofessional approach effectively strengthened medication literacy in the island community and is recommended for replication in other hinterland areas with sustained mentoring through posyandu.
Co-Authors Agustina, Nurul Albasithu, M Farhan Aldhehita Ari Kusumawati Aldhehita Ari Kusumawati Aldhehita Ari Kusumawati Alysa Dwirini Andini Putri Cecep Kusmana Djoko Wahyono Djoko Wahyono Dwi Ratna Fitriyani Elfasyari, Trie Yuni Endang Yuniarti Fendi Hidayat Hamid, Hazrina Binti Helda Muliana Heldi Candra Heldi Candra Heldi Candra Hidayati Hidayati Hidayati Hidayati Hidayati Hilda Muliana Hilda Muliana Ika Novita Sari Isramilda, Isramilda Istiqomah, Iffah Nur Kartini Hasballah Kurnia, Claudia Angelina Kusumawati, Aldhehita Ari Lita Riastienanda Putri Lita Riastienanda Putri Marsyanda Azzahra Rizqy Mukhamad Najib Mursal Nasya Efrilianda Putri Nisa Andryani Nadapdap Nugrahani, Andita Nursyidah, Nursyidah Putri Meisa Anggesta Rizki Yuli Sari Satria, Mohd Rhana Sri Nova Deltu Sri Nova Deltu Sri Nova Deltu Suci Wahyuliza Ulinnuha, Anisa Wilda Fasim Hasibuan Wilda Fasim Hasibuan Yoga Fitriana Yundelfa, Mandria Zaki Mubarak