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All Journal Jurnal Kesehatan Bakti Tunas Husada Journal of Pharmacopolium
Yuliantini, Anne
Sekolah Tinggi Farmasi Bandung, Jl. Soekarno Hatta No.754 Bandung Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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DETEKSI FORMALIN DALAM MAKANAN DENGAN INDIKATOR ALAMI DARI EKSTRAK BUNGA TELANG (CLITORIA TERNATEA L.) Yuliantini, Anne
Journal of Pharmacopolium Vol 1, No 3 (2018)
Publisher : STIKes Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.623 KB)

Abstract

Anthocyanin is a plant dye that can change in the presence of protein. Formalin-containing foods such as fish, chicken, wet noodles, and tofu have proteins that can methylene bond with formalin so that the protein becomes damaged. Anthocyanin color will be change if added to proteins that contain formalin and only protein because proteins are able to change and stabilize anthocyanin color. This study aims to detect the presence of formalin in foods with telang flower extract (Clitoria ternatea L.) which contains high levels of blue anthocyanins. The method used in this study is the result of visual observations assisted by visible spectrophotometer and confirmed by chromatropic acid method. The results showed that the flower extract of telang ethanol was able to detect formalin in food by not showing discoloration when added with telang flower extract which gradually turned into greenish ash while for the negative color results it was stabilized green turkey with a limit of detection of fish, chicken, wet noodles , and know, respectively 1.9654; 1,6987; 2,2514; and 1.5821 mg / g, with a SBR value of 10.845; 9,372; 22,625; and 5.908%. From the results of testing the samples with telang flower extract showed 4 positive samples while the chromatropic acid method 6 positive samples contained formalin.
PENETAPAN KADAR DEKSAMETASON DAN DEKSKLORFENIRAMIN MALEAT SECARA SIMULTAN PADA SEDIAAN SIRUP MENGGUNAKAN METODE KCKT Yuliantini, Anne
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 17, No 2 (2017)
Publisher : STIKes Bakti Tunas Husada Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (378.536 KB) | DOI: 10.36465/jkbth.v17i2.266

Abstract

Salah satu sirup yang mengandung lebih dari satu macam zat aktif adalah sirup campuran deksametason dan deksklorfeniramin maleat. Untuk menjamin kualitas sediaan obat, dilakukan pemeriksaan kadar zat aktif dalam sirup campuran deksametason dan deksklorfeniramin maleat. Tujuan penelitian ini adalahh mendapatkan metode alternatif dalam menentukan kadar deksametason dan deksklorfeniramin maleat secara simultan pada sediaan sirup yang beredar dipasaran dengan metode KCKT yang telah dikembangkan. Analisis dilakukan dengan metode KCKT fase balik dengan kolom C18, fase gerak air-asetonitril (65:35,V/V), laju alir 1,0 mL/menit dan panjang gelombang pengamatan adalah 241 nm. Hasil validasi metode diperoleh nilai batas deteksi, batas kuantisasi, koefisien korelasi, persen perolehan kembali dan nilai RSD yang baik. Dari hasil pengukuran sampel, didapatkan bahwa sampel 1 dan 2 mengandung sebesar 103,383% dan 102,626% (deksametason) dan 102,454% dan 99,349% (deksklorfeniramin maleat) sesuai dengan persyaratan kadar yang terdapat dalam FI V (90,0%-110,0%). Metode KCKT dapat digunakan untuk menentukan kadar dalam sediaan sirup deksametason dan deksklorfeniramin maleat secara simultan.
Co-Authors ., Noneng Juliana, Vina